MCID: LWT001
MIFTS: 40

Low Tension Glaucoma

Categories: Eye diseases

Aliases & Classifications for Low Tension Glaucoma

MalaCards integrated aliases for Low Tension Glaucoma:

Name: Low Tension Glaucoma 12 56 45 15 17 74
Normal Tension Glaucoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13544
ICD9CM 36 365.12
MeSH 45 D057066
SNOMED-CT 69 50485007
ICD10 34 H40.12
UMLS 74 C0152136

Summaries for Low Tension Glaucoma

MalaCards based summary : Low Tension Glaucoma, also known as normal tension glaucoma, is related to glaucoma, normal tension and ocular hypertension. An important gene associated with Low Tension Glaucoma is OPTN (Optineurin), and among its related pathways/superpathways is Neuroscience. The drugs Timolol and Travoprost have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and brain, and related phenotypes are no phenotypic analysis and vision/eye

Related Diseases for Low Tension Glaucoma

Diseases related to Low Tension Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 glaucoma, normal tension 32.2 OPA1 OPTN
2 ocular hypertension 30.3 MYOC OPTN
3 yemenite deaf-blind hypopigmentation syndrome 30.1 OPTN RHO
4 primary angle-closure glaucoma 30.1 MYOC OPTN
5 optic nerve disease 29.6 EDN1 MYOC OPA1 OPTN
6 glaucoma, primary open angle 29.3 ATOH7 CDKN2B-AS1 GAS7 MYOC OPTN WDR36
7 open-angle glaucoma 29.3 ATOH7 CDKN2B-AS1 GAS7 MYOC OPTN TBK1
8 glaucoma 1, open angle, p 11.2
9 intraocular pressure quantitative trait locus 11.2
10 sleep apnea 10.4
11 alzheimer disease 10.3
12 glaucoma 1, open angle, a 10.3 MYOC OPTN
13 apnea, obstructive sleep 10.3
14 excessive tearing 10.3 MYOC OPTN
15 diffuse meningeal melanocytosis 10.3 EDN1 OPTN
16 cataract 10.3
17 myopia 10.3
18 acute retrobulbar neuritis 10.2 EDN1 RHO
19 corneal edema 10.2 MYOC OPTN
20 retinal vein occlusion 10.2
21 scotoma 10.2
22 episodic ataxia, type 6 10.2 SLC1A1 SLC1A3
23 3-methylglutaconic aciduria, type iii 10.1
24 retinal degeneration 10.1
25 primary congenital glaucoma 10.1 MYOC OPTN WDR36
26 juvenile glaucoma 10.1 MYOC OPTN WDR36
27 dicarboxylic aminoaciduria 10.1 SLC1A1 SLC1A3
28 glaucoma 3, primary congenital, a 10.1 MYOC OPTN
29 exfoliation syndrome 10.1
30 retinoschisis 1, x-linked, juvenile 10.1
31 kearns-sayre syndrome 10.1
32 keratoconus 10.1
33 chronic closed-angle glaucoma 10.1
34 neuropathy 10.1
35 nervous system disease 10.0 OPTN RHO TBK1
36 systemic lupus erythematosus 9.9
37 optic atrophy 1 9.9
38 optic nerve hypoplasia, bilateral 9.9
39 hydrocephalus, normal-pressure 9.9
40 helicobacter pylori infection 9.9
41 glaucoma 1, open angle, f 9.9
42 occult macular dystrophy 9.9
43 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
44 hydrocephalus 9.9
45 atrial fibrillation 9.9
46 sensorineural hearing loss 9.9
47 central retinal vein occlusion 9.9
48 thrombophilia 9.9
49 retinal vascular disease 9.9
50 cerebrovascular disease 9.9

Graphical network of the top 20 diseases related to Low Tension Glaucoma:



Diseases related to Low Tension Glaucoma

Symptoms & Phenotypes for Low Tension Glaucoma

MGI Mouse Phenotypes related to Low Tension Glaucoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.35 MYOC OPTN RHO SLC1A3 TBK1
2 vision/eye MP:0005391 9.1 ATOH7 MYOC OPA1 RHO SLC1A1 SLC1A3

Drugs & Therapeutics for Low Tension Glaucoma

Drugs for Low Tension Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 50)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Timolol Approved Phase 4,Phase 2,Not Applicable 26839-75-8 5478 33624
2
Travoprost Approved Phase 4 157283-68-6 5282226
3
Brinzolamide Approved Phase 4 138890-62-7 68844
4
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
5
Dipivefrin Approved Phase 4,Not Applicable 52365-63-6 3105
6
Maleic acid Experimental, Investigational Phase 4 110-17-8, 110-16-7 444972
7 Adrenergic Agents Phase 4,Phase 2,Not Applicable
8 Brimonidine Tartrate, Timolol Maleate Drug Combination Phase 4
9 Adrenergic alpha-Agonists Phase 4,Phase 2,Not Applicable
10 Ophthalmic Solutions Phase 4,Phase 2,Not Applicable
11 Antihypertensive Agents Phase 4,Phase 2,Not Applicable
12 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Not Applicable
13 Anti-Arrhythmia Agents Phase 4,Phase 2,Not Applicable
14 Brimonidine Tartrate Phase 4,Phase 2,Not Applicable 70359-46-5
15 Adrenergic beta-Antagonists Phase 4,Phase 2,Not Applicable
16 Adrenergic Antagonists Phase 4,Phase 2,Not Applicable
17 Adrenergic Agonists Phase 4,Phase 2,Not Applicable
18 Pharmaceutical Solutions Phase 4,Phase 2,Not Applicable
19 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
20 Carbonic Anhydrase Inhibitors Phase 4,Phase 2,Not Applicable
21 Benzalkonium Compounds Phase 4
22 Anti-Infective Agents Phase 4
23 Anti-Infective Agents, Local Phase 4
24
Dorzolamide Approved Phase 2,Not Applicable 120279-96-1 5284549 3154
25
Phenytoin Approved, Vet_approved 57-41-0 1775
26
Latanoprost Approved, Investigational Not Applicable 130209-82-4 5311221 5282380
27
Dexamethasone acetate Approved, Investigational, Vet_approved 1177-87-3
28
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
29 Diuretics, Potassium Sparing
30 Convulsants
31 Sodium Channel Blockers
32 Anticonvulsants
33
Bilirubin 635-65-4, 69853-43-6 21252250 5280352
34 Antioxidants
35 Protective Agents
36 Anesthetics ,Not Applicable
37 Central Nervous System Depressants
38 Proxymetacaine Not Applicable
39 Ginkgo Not Applicable
40 Peripheral Nervous System Agents
41 Hormones, Hormone Substitutes, and Hormone Antagonists
42 Hormones
43 Gastrointestinal Agents
44 Antiemetics
45 glucocorticoids
46 Autonomic Agents
47 Antineoplastic Agents, Hormonal
48 Anti-Inflammatory Agents
49 BB 1101
50 Hormone Antagonists

Interventional clinical trials:

(show top 50) (show all 63)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety Study of Combigan and 0.5% Timoptic in Normal Tension Glaucoma Unknown status NCT01446497 Phase 4 Brimonidine/Timolol mixed combination;Timolol
2 Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma Completed NCT01995136 Phase 4 Travoprost Ophthalmic Solution 0.004%
3 Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma Completed NCT03150160 Phase 4 brinzolamide 1%/brimonidine 0.2% fixed combination;Placebo;travoprost 0.004% ophthalmic solution
4 Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG) Completed NCT02863705 Phase 4 brimonidine tartrate/timolol malate Ophthalmic Solution;bimatoprost ophthalmic solution 0.01%
5 Effect of Selective Laser Trabeculoplasty Versus Travoprost on Circardian Intraocular Pressure Completed NCT02105311 Phase 4 Travoprost
6 Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study Active, not recruiting NCT03323164 Phase 4 Timolol Maleate;Brimonidine Tartrate
7 Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma Completed NCT03106532 Phase 2 PHP-201 0.25% ophthalmic solution;PHP-201 0.5% ophthalmic solution;Placebo ophthalmic solution
8 COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED) Completed NCT00832377 Phase 2 timolol/dorzolamide combination
9 Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma Completed NCT00317577 Phase 2 brimonidine, timolol
10 Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging Recruiting NCT01864317 Phase 2
11 Psychopathology of Normal-tension Glaucoma in Hong Kong Chinese Out-patient Unknown status NCT00324181
12 Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma Unknown status NCT00321386
13 Metabolomics in Surgical Ophthalmological Patients Unknown status NCT03098316
14 Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma Unknown status NCT01795014
15 Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins Unknown status NCT01794442
16 Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition Unknown status NCT00306657 Not Applicable
17 Protective Effect of Phenytoin on Glaucoma Unknown status NCT00739154
18 Blood Flow of Ophthalmic Artery and Glaucoma Unknown status NCT02656979 Not Applicable Latanoprost
19 Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS) Unknown status NCT00874913 Not Applicable
20 Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348672
21 Pressure Difference Between Brain and Eye: a Possible Cause to Normal Tension Glaucoma. Completed NCT02776449
22 Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension Glaucoma Completed NCT01175902 Not Applicable dorzolamide/timolol;latanoprost
23 Observational Study of the Long-term Effect of Latanoprost in Normal Tension Glaucoma Completed NCT01209624
24 Serum Bilirubin Levels in Normal-tension Glaucoma Completed NCT03387306
25 Systemic Glutathione Level in Normal Tension Glaucoma Completed NCT00570362
26 Autonomic Nervous System Activity and Normal Tension Glaucoma Completed NCT01192061
27 A New View of Normal Tension Glaucoma: Autoregulation and Systemic Blood Pressure Completed NCT00706056
28 Magnetic Resonance Imaging of Patients With Normal Tension Glaucoma Completed NCT00175786
29 Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients Completed NCT01487655
30 Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure Glaucoma Completed NCT01105065 Not Applicable brimonidine 0.15%
31 Isometric Exercise in NTG Completed NCT03921372 Not Applicable
32 Spectral Domain Optical Coherence Tomography Analysis for Glaucoma Completed NCT01612416 Not Applicable
33 Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation Completed NCT01391247
34 Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma Completed NCT01912599 Not Applicable
35 Ocular Blood Flow in Glaucoma Patients - the Leuven Eye Study Completed NCT01840202
36 Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma Completed NCT01488032
37 IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic Completed NCT01254149
38 Alcon® Ex-PRESS® Glaucoma Filtration Device in Japanese Patients Completed NCT02246777 Not Applicable
39 Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments. Completed NCT00347191
40 Study on Ocular Blood Flow and the Orbital Cerebrospinal Fluid Pressure in Glaucoma Completed NCT01802463
41 Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy Completed NCT01862627
42 Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAG Completed NCT01769521 Not Applicable
43 Advanced Glycation End Products as a Biomarker for Accelerated Ageing Completed NCT02863224
44 Evaluation of Corneal Temperature by Infrared Thermography in Glaucoma Patients Completed NCT02674074 Not Applicable
45 Analysis of Visual Pathways in Glaucoma Patients Using a 3tesla-MRI Completed NCT01621841
46 Correlation of Optic Disk Morphology and Ocular Perfusion Parameters in Patients With Primary Open Angle Glaucoma Completed NCT00803504
47 Clinical and Molecular Studies in Families With Glaucoma and Related Diseases Completed NCT00272363
48 Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects Completed NCT00712400 Not Applicable Latanoprost 0.005%, Xalatan®;Placebo
49 Intraocular Pressure and Hemodialysis Midwestern Brazil Completed NCT02405884 Not Applicable
50 Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines? Completed NCT00430287

Search NIH Clinical Center for Low Tension Glaucoma

Cochrane evidence based reviews: low tension glaucoma

Genetic Tests for Low Tension Glaucoma

Anatomical Context for Low Tension Glaucoma

MalaCards organs/tissues related to Low Tension Glaucoma:

42
Eye, Testes, Brain, Heart, Endothelial, Retina, Cerebellum

Publications for Low Tension Glaucoma

Articles related to Low Tension Glaucoma:

(show top 50) (show all 882)
# Title Authors Year
1
Optic disc cupping characteristics of normal pressure hydrocephalus patients with normal-tension glaucoma. ( 30816215 )
2019
2
Low-Tension Glaucoma: An Oxymoron in Ophthalmology. ( 30676934 )
2019
3
Quantitative Analysis of Retinal and Choroidal Vascular Parameters in Patients with Low Tension Glaucoma. ( 30889061 )
2019
4
Different Disc Characteristics Associated With High Myopia and the Location of Glaucomatous Damage in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma. ( 30789526 )
2019
5
Optical Coherence Tomography Angiography of Optic Disc in Eyes With Primary Open-angle Glaucoma and Normal-tension Glaucoma. ( 30624391 )
2019
6
Comparison of Visual Field Progression Rates Among the High Tension Glaucoma, Primary Angle Closure Glaucoma, and Normal Tension Glaucoma. ( 30835290 )
2019
7
Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. ( 30692515 )
2019
8
Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images. ( 31108550 )
2019
9
Correlation between Basal Macular Circulation and Following Glaucomatous Damage in Progressed High-Tension and Normal-Tension Glaucoma. ( 31104053 )
2019
10
Melanopsin-mediated pupillary light reflex and sleep quality in patients with normal tension glaucoma. ( 31062491 )
2019
11
Risk factors for disease progression in low-teens normal-tension glaucoma. ( 31055450 )
2019
12
Differences in Optic Nerve Head Blood Flow Regulation in Normal Tension Glaucoma Patients and Healthy Controls as Assessed with Laser Speckle Flowgraphy During the Water Drinking Test. ( 30950964 )
2019
13
Topographic correlation between macular superficial microvessel density and ganglion cell-inner plexiform layer thickness in glaucoma-suspect and early normal-tension glaucoma. ( 30940619 )
2019
14
When 'glaucomatous fields' are not glaucoma: bilateral calcarine fissure strokes masquerading as glaucoma in a normal tension glaucoma suspect. ( 30902842 )
2019
15
Relationship between macular vessel density and focal electroretinograms in early normal tension glaucoma. ( 30869542 )
2019
16
Baseline Systolic Versus Diastolic Blood Pressure Dip and Subsequent Visual Field Progression in Normal-Tension Glaucoma. ( 30853468 )
2019
17
Myocilin Mutations in Patients With Normal-Tension Glaucoma. ( 30816940 )
2019
18
Corneal Biomechanics Using a Scheimpflug-Based Noncontact Device in Normal-Tension Glaucoma and Healthy Controls. ( 30773853 )
2019
19
Re: "The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study" by Jin and Lee (J. Ocul. Pharmacol. Ther. 34:274-279, 2018). ( 30699063 )
2019
20
Response to Chua et al. re: "The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study". ( 30699062 )
2019
21
Normal-tension glaucoma: managing a case of mistaken identity. ( 30652387 )
2019
22
Normal-tension glaucoma: Pathogenesis and genetics. ( 30651837 )
2019
23
Intraocular pressure change during laparoscopic sacral colpopexy in patients with normal tension glaucoma. ( 30643979 )
2019
24
Segmental inner macular layer analysis with spectral-domain optical coherence tomography for early detection of normal tension glaucoma. ( 30629663 )
2019
25
The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study. ( 30624389 )
2019
26
The association between prelaminar tissue thickness and peripapillary choroidal thickness in untreated normal-tension glaucoma patients. ( 30608458 )
2019
27
Management of normal tension glaucoma. ( 30514477 )
2019
28
Prevalence of Normal-Tension Glaucoma in the Chinese Population: A Systematic Review and Meta-Analysis. ( 30352196 )
2019
29
Using Kalman Filtering to Forecast Disease Trajectory for Patients With Normal Tension Glaucoma. ( 30336130 )
2019
30
Association of Angle Width With Progression of Normal-Tension Glaucoma: A Minimum 7-Year Follow-up Study. ( 30326036 )
2019
31
Investigation of whole mitochondrial genome variation in normal tension glaucoma. ( 30312593 )
2019
32
Intraocular pressure-independent management of normal tension glaucoma. ( 30300625 )
2019
33
Managing normal tension glaucoma by lowering the intraocular pressure. ( 30300624 )
2019
34
Disc haemorrhages in Polish Caucasian patients with normal tension glaucoma. ( 30284408 )
2019
35
Intraocular Pressure (IOP) Change and Frequency of IOP Spike After Cataract Surgery in Normal-tension Glaucoma: A Case-control Study. ( 30601222 )
2018
36
Comparison of intraocular pressure fluctuation before and after cataract surgeries in normal-tension glaucoma patients. ( 30255729 )
2018
37
Ocular Hemodynamics in Acute Nonarteritic Anterior Ischemic Optic Neuropathy Compared to Normal Tension Glaucoma. ( 30601221 )
2018
38
Optical Coherence Tomography Angiography of the Peripapillary Retina in Normal-Tension Glaucoma and Chronic Nonarteritic Anterior Ischemic Optic Neuropathy. ( 29451992 )
2018
39
Blood Pressure and Heart Rate Variability in Primary Open-Angle Glaucoma and Normal Tension Glaucoma. ( 30110187 )
2018
40
Intraocular retinal thickness asymmetry in early stage of primary open angle glaucoma and normal tension glaucoma. ( 30140639 )
2018
41
Measurement and Associations of the Optic Nerve Subarachnoid Space in Normal Tension Glaucoma and Primary Open-Angle Glaucoma. ( 29628114 )
2018
42
Carbohydrate ingestion induces differential autonomic dysregulation in normal-tension glaucoma and primary open angle glaucoma. ( 29879162 )
2018
43
Oxygen venular saturation correlates with a functional loss in primary open-angle glaucoma and normal-tension glaucoma patients. ( 29090841 )
2018
44
The Association of Single-Nucleotide Polymorphisms in the MMP-9 Gene with Normal Tension Glaucoma and Primary Open-Angle Glaucoma. ( 29199866 )
2018
45
The relationship between optic atrophy 1 polymorphism and normal tension glaucoma in Taiwan. ( 30038886 )
2018
46
Association between normal tension glaucoma and the risk of Alzheimer's disease: a nationwide population-based cohort study in Taiwan. ( 30397009 )
2018
47
Ocular hypotensive effects of prostaglandin analogs in Japanese patients with normal-tension glaucoma: a literature review. ( 30275680 )
2018
48
Long-term rate of progression and target intraocular pressure in patients with normal-tension glaucoma in clinical care. ( 30259686 )
2018
49
Re: Lindén et al.: Normal-tension glaucoma has normal intracranial pressure: a prospective study of intracranial pressure and intraocular pressure in different body positions (Ophthalmology. 2018;125:361-368). ( 30243345 )
2018
50
Effect of quantitative intraocular pressure reduction on visual field defect progression in normal tension glaucoma under medical therapy applying Markov model. ( 30214146 )
2018

Variations for Low Tension Glaucoma

Expression for Low Tension Glaucoma

Search GEO for disease gene expression data for Low Tension Glaucoma.

Pathways for Low Tension Glaucoma

Pathways related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 OPTN RHO SLC1A1 SLC1A3

GO Terms for Low Tension Glaucoma

Biological processes related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.69 CDKN2B-AS1 EDN1 TBK1
2 positive regulation of cell migration GO:0030335 9.67 CDKN2B-AS1 EDN1 MYOC
3 visual perception GO:0007601 9.65 OPA1 RHO WDR36
4 amino acid transport GO:0006865 9.52 SLC1A1 SLC1A3
5 response to light stimulus GO:0009416 9.46 RHO SLC1A3
6 positive regulation of heart rate GO:0010460 9.43 EDN1 SLC1A1
7 glutamate secretion GO:0014047 9.4 SLC1A1 SLC1A3
8 L-glutamate transmembrane transport GO:0015813 9.37 SLC1A1 SLC1A3
9 L-glutamate import across plasma membrane GO:0098712 9.32 SLC1A1 SLC1A3
10 positive regulation of xenophagy GO:1904417 9.26 OPTN TBK1
11 D-aspartate import across plasma membrane GO:0070779 9.16 SLC1A1 SLC1A3
12 L-glutamate import GO:0051938 8.96 SLC1A1 SLC1A3
13 L-aspartate import across plasma membrane GO:0140009 8.62 SLC1A1 SLC1A3

Molecular functions related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-glutamate transmembrane transporter activity GO:0005313 9.26 SLC1A1 SLC1A3
2 glutamate binding GO:0016595 9.16 SLC1A1 SLC1A3
3 high-affinity glutamate transmembrane transporter activity GO:0005314 8.96 SLC1A1 SLC1A3
4 glutamate:sodium symporter activity GO:0015501 8.62 SLC1A1 SLC1A3

Sources for Low Tension Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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