MCID: LWT001
MIFTS: 40

Low Tension Glaucoma

Categories: Eye diseases

Aliases & Classifications for Low Tension Glaucoma

MalaCards integrated aliases for Low Tension Glaucoma:

Name: Low Tension Glaucoma 12 56 45 15 17 74
Normal Tension Glaucoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13544
ICD9CM 36 365.12
MeSH 45 D057066
SNOMED-CT 69 50485007
ICD10 34 H40.12
UMLS 74 C0152136

Summaries for Low Tension Glaucoma

MalaCards based summary : Low Tension Glaucoma, also known as normal tension glaucoma, is related to glaucoma, normal tension and ocular hypertension. An important gene associated with Low Tension Glaucoma is OPTN (Optineurin), and among its related pathways/superpathways is Neuroscience. The drugs Timolol and Travoprost have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and brain, and related phenotypes are no phenotypic analysis and vision/eye

Related Diseases for Low Tension Glaucoma

Diseases related to Low Tension Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 glaucoma, normal tension 32.2 OPA1 OPTN
2 ocular hypertension 30.2 MYOC OPTN
3 yemenite deaf-blind hypopigmentation syndrome 30.1 OPTN RHO
4 primary angle-closure glaucoma 30.0 MYOC OPTN
5 optic nerve disease 29.6 EDN1 MYOC OPA1 OPTN
6 glaucoma, primary open angle 29.3 ATOH7 CDKN2B-AS1 GAS7 MYOC OPTN WDR36
7 open-angle glaucoma 29.2 ATOH7 CDKN2B-AS1 GAS7 MYOC OPTN TBK1
8 glaucoma 1, open angle, p 11.2
9 intraocular pressure quantitative trait locus 11.2
10 sleep apnea 10.4
11 alzheimer disease 10.3
12 glaucoma 1, open angle, a 10.3 MYOC OPTN
13 excessive tearing 10.3 MYOC OPTN
14 apnea, obstructive sleep 10.3
15 cleft mitral valve 10.3
16 diffuse meningeal melanocytosis 10.3 EDN1 OPTN
17 cataract 10.3
18 myopia 10.3
19 acute retrobulbar neuritis 10.2 EDN1 RHO
20 corneal edema 10.2 MYOC OPTN
21 retinal vein occlusion 10.2
22 scotoma 10.2
23 episodic ataxia, type 6 10.2 SLC1A1 SLC1A3
24 3-methylglutaconic aciduria, type iii 10.1
25 retinal degeneration 10.1
26 primary congenital glaucoma 10.1 MYOC OPTN WDR36
27 juvenile glaucoma 10.1 MYOC OPTN WDR36
28 dicarboxylic aminoaciduria 10.1 SLC1A1 SLC1A3
29 glaucoma 3, primary congenital, a 10.1 MYOC OPTN
30 kearns-sayre syndrome 10.1
31 keratoconus 10.1
32 chronic closed-angle glaucoma 10.1
33 dural sinus malformation 10.1
34 neuropathy 10.1
35 nervous system disease 10.0 OPTN RHO TBK1
36 systemic lupus erythematosus 9.9
37 optic atrophy 1 9.9
38 optic nerve hypoplasia, bilateral 9.9
39 exfoliation syndrome 9.9
40 hydrocephalus, normal-pressure 9.9
41 helicobacter pylori infection 9.9
42 occult macular dystrophy 9.9
43 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
44 hydrocephalus 9.9
45 atrial fibrillation 9.9
46 sensorineural hearing loss 9.9
47 central retinal vein occlusion 9.9
48 thrombophilia 9.9
49 retinal vascular disease 9.9
50 cerebrovascular disease 9.9

Graphical network of the top 20 diseases related to Low Tension Glaucoma:



Diseases related to Low Tension Glaucoma

Symptoms & Phenotypes for Low Tension Glaucoma

MGI Mouse Phenotypes related to Low Tension Glaucoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.35 MYOC OPTN RHO SLC1A3 TBK1
2 vision/eye MP:0005391 9.1 ATOH7 MYOC OPA1 RHO SLC1A1 SLC1A3

Drugs & Therapeutics for Low Tension Glaucoma

Drugs for Low Tension Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 50)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Timolol Approved Phase 4,Phase 2,Not Applicable 26839-75-8 33624 5478
2
Travoprost Approved Phase 4 157283-68-6 5282226
3
Brinzolamide Approved Phase 4 138890-62-7 68844
4
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
5
Dipivefrin Approved Phase 4,Not Applicable 52365-63-6 3105
6
SB-649868 Experimental, Investigational Phase 4 110-16-7, 110-17-8 444972
7 Adrenergic Antagonists Phase 4,Phase 2,Not Applicable
8 Brimonidine Tartrate, Timolol Maleate Drug Combination Phase 4
9 Brimonidine Tartrate Phase 4,Phase 2,Not Applicable 70359-46-5
10 Adrenergic beta-Antagonists Phase 4,Phase 2,Not Applicable
11 Adrenergic Agonists Phase 4,Phase 2,Not Applicable
12 Anti-Arrhythmia Agents Phase 4,Phase 2,Not Applicable
13 Ophthalmic Solutions Phase 4,Phase 2,Not Applicable
14 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Not Applicable
15 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
16 Adrenergic alpha-Agonists Phase 4,Phase 2,Not Applicable
17 Adrenergic Agents Phase 4,Phase 2,Not Applicable
18 Antihypertensive Agents Phase 4,Phase 2,Not Applicable
19 Pharmaceutical Solutions Phase 4,Phase 2,Not Applicable
20 Carbonic Anhydrase Inhibitors Phase 4,Phase 2,Not Applicable
21 Anti-Infective Agents Phase 4
22 Benzalkonium Compounds Phase 4
23 Anti-Infective Agents, Local Phase 4
24
Dorzolamide Approved Phase 2,Not Applicable 120279-96-1 3154 5284549
25
Phenytoin Approved, Vet_approved 57-41-0 1775
26
Latanoprost Approved, Investigational Not Applicable 130209-82-4 5311221 5282380
27
Dexamethasone acetate Approved, Investigational, Vet_approved 1177-87-3
28
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
29 Diuretics, Potassium Sparing
30 Anticonvulsants
31 Sodium Channel Blockers
32 Convulsants
33
Bilirubin 635-65-4, 69853-43-6 5280352 21252250
34 Protective Agents
35 Antioxidants
36 Anesthetics ,Not Applicable
37 Central Nervous System Depressants
38 Proxymetacaine Not Applicable
39 Ginkgo Not Applicable
40 Peripheral Nervous System Agents
41 Anti-Inflammatory Agents
42 Autonomic Agents
43 BB 1101
44 Hormones
45 glucocorticoids
46 Hormones, Hormone Substitutes, and Hormone Antagonists
47 Gastrointestinal Agents
48 Antineoplastic Agents, Hormonal
49 Hormone Antagonists
50 Antiemetics

Interventional clinical trials:

(show top 50) (show all 62)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety Study of Combigan and 0.5% Timoptic in Normal Tension Glaucoma Unknown status NCT01446497 Phase 4 Brimonidine/Timolol mixed combination;Timolol
2 Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma Completed NCT01995136 Phase 4 Travoprost Ophthalmic Solution 0.004%
3 Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma Completed NCT03150160 Phase 4 brinzolamide 1%/brimonidine 0.2% fixed combination;Placebo;travoprost 0.004% ophthalmic solution
4 Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG) Completed NCT02863705 Phase 4 brimonidine tartrate/timolol malate Ophthalmic Solution;bimatoprost ophthalmic solution 0.01%
5 Effect of Selective Laser Trabeculoplasty Versus Travoprost on Circardian Intraocular Pressure Completed NCT02105311 Phase 4 Travoprost
6 Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study Active, not recruiting NCT03323164 Phase 4 Timolol Maleate;Brimonidine Tartrate
7 Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma Completed NCT03106532 Phase 2 PHP-201 0.25% ophthalmic solution;PHP-201 0.5% ophthalmic solution;Placebo ophthalmic solution
8 COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED) Completed NCT00832377 Phase 2 timolol/dorzolamide combination
9 Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma Completed NCT00317577 Phase 2 brimonidine, timolol
10 Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging Recruiting NCT01864317 Phase 2
11 Psychopathology of Normal-tension Glaucoma in Hong Kong Chinese Out-patient Unknown status NCT00324181
12 Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma Unknown status NCT00321386
13 Metabolomics in Surgical Ophthalmological Patients Unknown status NCT03098316
14 Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma Unknown status NCT01795014
15 Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins Unknown status NCT01794442
16 Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition Unknown status NCT00306657 Not Applicable
17 Protective Effect of Phenytoin on Glaucoma Unknown status NCT00739154
18 Blood Flow of Ophthalmic Artery and Glaucoma Unknown status NCT02656979 Not Applicable Latanoprost
19 Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS) Unknown status NCT00874913 Not Applicable
20 Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348672
21 Pressure Difference Between Brain and Eye: a Possible Cause to Normal Tension Glaucoma. Completed NCT02776449
22 Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension Glaucoma Completed NCT01175902 Not Applicable dorzolamide/timolol;latanoprost
23 Observational Study of the Long-term Effect of Latanoprost in Normal Tension Glaucoma Completed NCT01209624
24 Serum Bilirubin Levels in Normal-tension Glaucoma Completed NCT03387306
25 Systemic Glutathione Level in Normal Tension Glaucoma Completed NCT00570362
26 Autonomic Nervous System Activity and Normal Tension Glaucoma Completed NCT01192061
27 A New View of Normal Tension Glaucoma: Autoregulation and Systemic Blood Pressure Completed NCT00706056
28 Magnetic Resonance Imaging of Patients With Normal Tension Glaucoma Completed NCT00175786
29 Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients Completed NCT01487655
30 Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure Glaucoma Completed NCT01105065 Not Applicable brimonidine 0.15%
31 Spectral Domain Optical Coherence Tomography Analysis for Glaucoma Completed NCT01612416 Not Applicable
32 Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation Completed NCT01391247
33 Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma Completed NCT01912599 Not Applicable
34 Ocular Blood Flow in Glaucoma Patients - the Leuven Eye Study Completed NCT01840202
35 Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma Completed NCT01488032
36 IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic Completed NCT01254149
37 Alcon® Ex-PRESS® Glaucoma Filtration Device in Japanese Patients Completed NCT02246777 Not Applicable
38 Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments. Completed NCT00347191
39 Study on Ocular Blood Flow and the Orbital Cerebrospinal Fluid Pressure in Glaucoma Completed NCT01802463
40 Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy Completed NCT01862627
41 Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAG Completed NCT01769521 Not Applicable
42 Evaluation of Corneal Temperature by Infrared Thermography in Glaucoma Patients Completed NCT02674074 Not Applicable
43 Analysis of Visual Pathways in Glaucoma Patients Using a 3tesla-MRI Completed NCT01621841
44 Correlation of Optic Disk Morphology and Ocular Perfusion Parameters in Patients With Primary Open Angle Glaucoma Completed NCT00803504
45 Clinical and Molecular Studies in Families With Glaucoma and Related Diseases Completed NCT00272363
46 Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects Completed NCT00712400 Not Applicable Latanoprost 0.005%, Xalatan®;Placebo
47 Intraocular Pressure and Hemodialysis Midwestern Brazil Completed NCT02405884 Not Applicable
48 Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines? Completed NCT00430287
49 Study on the Impact of Ocular Anesthetic Procedures in Ocular Blood Flow Completed NCT01840215
50 Will Listening to Music Make it Easier to Take a Visual Field Test? Completed NCT01027039

Search NIH Clinical Center for Low Tension Glaucoma

Cochrane evidence based reviews: low tension glaucoma

Genetic Tests for Low Tension Glaucoma

Anatomical Context for Low Tension Glaucoma

MalaCards organs/tissues related to Low Tension Glaucoma:

42
Eye, Testes, Brain, Heart, Endothelial, Cerebellum, Retina

Publications for Low Tension Glaucoma

Articles related to Low Tension Glaucoma:

(show top 50) (show all 741)
# Title Authors Year
1
Optic disc cupping characteristics of normal pressure hydrocephalus patients with normal-tension glaucoma. ( 30816215 )
2019
2
Low-Tension Glaucoma: An Oxymoron in Ophthalmology. ( 30676934 )
2019
3
Quantitative Analysis of Retinal and Choroidal Vascular Parameters in Patients with Low Tension Glaucoma. ( 30889061 )
2019
4
Different Disc Characteristics Associated With High Myopia and the Location of Glaucomatous Damage in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma. ( 30789526 )
2019
5
Optical Coherence Tomography Angiography of Optic Disc in Eyes With Primary Open-angle Glaucoma and Normal-tension Glaucoma. ( 30624391 )
2019
6
Comparison of Visual Field Progression Rates Among the High Tension Glaucoma, Primary Angle Closure Glaucoma, and Normal Tension Glaucoma. ( 30835290 )
2019
7
Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. ( 30692515 )
2019
8
Disc haemorrhages in Polish Caucasian patients with normal tension glaucoma. ( 30284408 )
2019
9
Managing normal tension glaucoma by lowering the intraocular pressure. ( 30300624 )
2019
10
Intraocular pressure-independent management of normal tension glaucoma. ( 30300625 )
2019
11
Management of normal tension glaucoma. ( 30514477 )
2019
12
The association between prelaminar tissue thickness and peripapillary choroidal thickness in untreated normal-tension glaucoma patients. ( 30608458 )
2019
13
The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study. ( 30624389 )
2019
14
Segmental inner macular layer analysis with spectral-domain optical coherence tomography for early detection of normal tension glaucoma. ( 30629663 )
2019
15
Intraocular pressure change during laparoscopic sacral colpopexy in patients with normal tension glaucoma. ( 30643979 )
2019
16
Normal-tension glaucoma: Pathogenesis and genetics. ( 30651837 )
2019
17
Normal-tension glaucoma: managing a case of mistaken identity. ( 30652387 )
2019
18
Response to Chua et al. re: "The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study". ( 30699062 )
2019
19
Re: "The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study" by Jin and Lee (J. Ocul. Pharmacol. Ther. 34:274-279, 2018). ( 30699063 )
2019
20
Corneal Biomechanics Using a Scheimpflug-Based Noncontact Device in Normal-Tension Glaucoma and Healthy Controls. ( 30773853 )
2019
21
Myocilin Mutations in Patients With Normal-Tension Glaucoma. ( 30816940 )
2019
22
Baseline Systolic Versus Diastolic Blood Pressure Dip and Subsequent Visual Field Progression in Normal-Tension Glaucoma. ( 30853468 )
2019
23
Relationship between macular vessel density and focal electroretinograms in early normal tension glaucoma. ( 30869542 )
2019
24
When 'glaucomatous fields' are not glaucoma: bilateral calcarine fissure strokes masquerading as glaucoma in a normal tension glaucoma suspect. ( 30902842 )
2019
25
Intraocular Pressure (IOP) Change and Frequency of IOP Spike After Cataract Surgery in Normal-tension Glaucoma: A Case-control Study. ( 30601222 )
2018
26
Comparison of intraocular pressure fluctuation before and after cataract surgeries in normal-tension glaucoma patients. ( 30255729 )
2018
27
Ocular Hemodynamics in Acute Nonarteritic Anterior Ischemic Optic Neuropathy Compared to Normal Tension Glaucoma. ( 30601221 )
2018
28
Blood Pressure and Heart Rate Variability in Primary Open-Angle Glaucoma and Normal Tension Glaucoma. ( 30110187 )
2018
29
Intraocular retinal thickness asymmetry in early stage of primary open angle glaucoma and normal tension glaucoma. ( 30140639 )
2018
30
The Association of Single-Nucleotide Polymorphisms in the MMP-9 Gene with Normal Tension Glaucoma and Primary Open-Angle Glaucoma. ( 29199866 )
2018
31
Measurement and Associations of the Optic Nerve Subarachnoid Space in Normal Tension Glaucoma and Primary Open-Angle Glaucoma. ( 29628114 )
2018
32
Oxygen venular saturation correlates with a functional loss in primary open-angle glaucoma and normal-tension glaucoma patients. ( 29090841 )
2018
33
The relationship between optic atrophy 1 polymorphism and normal tension glaucoma in Taiwan. ( 30038886 )
2018
34
Association between normal tension glaucoma and the risk of Alzheimer's disease: a nationwide population-based cohort study in Taiwan. ( 30397009 )
2018
35
The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study. ( 29297751 )
2018
36
Relationship between corneal biomechanical properties and structural biomarkers in patients with normal-tension glaucoma: a retrospective study. ( 29334923 )
2018
37
Ocular and Clinical Characteristics Associated with the Extent of Posterior Lamina Cribrosa Curve in Normal Tension Glaucoma. ( 29343781 )
2018
38
Heart rate variability in normal tension glaucoma: A case-control study. ( 29384857 )
2018
39
Association between meibomian gland dysfunction and compliance of topical prostaglandin analogs in patients with normal tension glaucoma. ( 29385185 )
2018
40
Long-term progression of visual field defects and related factors in medically treated normal tension glaucoma. ( 29440866 )
2018
41
Comparison of retinal microvascular changes in eyes with high-tension glaucoma or normal-tension glaucoma: a quantitative optic coherence tomography angiographic study. ( 29450622 )
2018
42
Results of Nailfold Capillaroscopy in Patients with Normal-Tension Glaucoma. ( 29451988 )
2018
43
Normal tension glaucoma: review of current understanding and mechanisms of the pathogenesis. ( 29456252 )
2018
44
Heart rate variability: the comparison between high tension and normal tension glaucoma. ( 29515686 )
2018
45
Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal-tension glaucoma. ( 29532640 )
2018
46
Laser speckle flowgraphy derived characteristics of optic nerve head perfusion in normal tension glaucoma and healthy individuals: a Pilot study. ( 29593269 )
2018
47
The clinical effectiveness of tafluprost on Japanese normal-tension glaucoma patients. ( 29593379 )
2018
48
The role of corneal hysteresis during the evaluation of patients with possible normal-tension glaucoma. ( 29606853 )
2018
49
White Matter Abnormalities and Correlation With Severity in Normal Tension Glaucoma: A Whole Brain Atlas-Based Diffusion Tensor Study. ( 29625454 )
2018
50
Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma. ( 29651339 )
2018

Variations for Low Tension Glaucoma

Expression for Low Tension Glaucoma

Search GEO for disease gene expression data for Low Tension Glaucoma.

Pathways for Low Tension Glaucoma

Pathways related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 OPTN RHO SLC1A1 SLC1A3

GO Terms for Low Tension Glaucoma

Biological processes related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.69 CDKN2B-AS1 EDN1 TBK1
2 positive regulation of cell migration GO:0030335 9.67 CDKN2B-AS1 EDN1 MYOC
3 visual perception GO:0007601 9.65 OPA1 RHO WDR36
4 amino acid transport GO:0006865 9.52 SLC1A1 SLC1A3
5 response to light stimulus GO:0009416 9.46 RHO SLC1A3
6 positive regulation of heart rate GO:0010460 9.43 EDN1 SLC1A1
7 glutamate secretion GO:0014047 9.4 SLC1A1 SLC1A3
8 L-glutamate transmembrane transport GO:0015813 9.37 SLC1A1 SLC1A3
9 L-glutamate import across plasma membrane GO:0098712 9.32 SLC1A1 SLC1A3
10 positive regulation of xenophagy GO:1904417 9.26 OPTN TBK1
11 D-aspartate import across plasma membrane GO:0070779 9.16 SLC1A1 SLC1A3
12 L-glutamate import GO:0051938 8.96 SLC1A1 SLC1A3
13 L-aspartate import across plasma membrane GO:0140009 8.62 SLC1A1 SLC1A3

Molecular functions related to Low Tension Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 amino acid transmembrane transporter activity GO:0015171 9.32 SLC1A1 SLC1A3
2 L-glutamate transmembrane transporter activity GO:0005313 9.26 SLC1A1 SLC1A3
3 glutamate binding GO:0016595 9.16 SLC1A1 SLC1A3
4 high-affinity glutamate transmembrane transporter activity GO:0005314 8.96 SLC1A1 SLC1A3
5 glutamate:sodium symporter activity GO:0015501 8.62 SLC1A1 SLC1A3

Sources for Low Tension Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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