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MCID: LNG095
MIFTS: 35

Lung Abscess

Categories: Respiratory diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
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Aliases & Classifications for Lung Abscess

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MalaCards integrated aliases for Lung Abscess:

Name: Lung Abscess 12 55 44 15 73

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:0060317
ICD10 33 J85.2 J85.1
ICD9CM 35 513.0
MeSH 44 D008169
NCIt 50 C99090
SNOMED-CT 68 73452002
UMLS 73 C0024110
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Summaries for Lung Abscess

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Disease Ontology : 12 A lung disease characterized by microbial infection which causes a type of liquefactive necrosis of the pulmonary tissue and formation of cavities containing necrotic debris or fluid.

MalaCards based summary : Lung Abscess is related to pneumonia and pleural empyema, and has symptoms including hemoptysis An important gene associated with Lung Abscess is LACTB (Lactamase Beta). The drugs Anti-Infective Agents and Antitubercular Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and brain.

Wikipedia : 76 Lung abscess is a type of liquefactive necrosis of the lung tissue and formation of cavities (more than... more...

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Related Diseases for Lung Abscess

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Diseases related to Lung Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
# Related Disease Score Top Affiliating Genes
1 pneumonia 30.6 LACTB MUC5B
2 pleural empyema 11.4
3 aspiration pneumonia 11.4
4 aspergillosis 11.4
5 anaerobic pneumonia 11.0
6 amebiasis 10.7
7 bronchiectasis 10.1
8 lipid pneumonia 10.0 FLNC MUC5B
9 osteomyelitis 10.0
10 pneumothorax 10.0
11 paranasal sinus disease 10.0 FLNC MUC5B
12 lung cancer 10.0
13 bronchial disease 10.0 FLNC MUC5B
14 otitis media 9.9 LACTB MUC5B
15 cystic fibrosis 9.9
16 legionellosis 9.9
17 klebsiella pneumonia 9.9
18 melioidosis 9.9
19 lymphoma 9.9
20 endocarditis 9.9
21 pyelonephritis 9.9
22 allergic bronchopulmonary aspergillosis 9.9
23 influenza 9.9
24 achalasia 9.9
25 mycobacterium fortuitum 9.9
26 respiratory system disease 9.9 FLNC MUC5B
27 gallbladder disease 1 9.8
28 legionnaire disease 9.8
29 ulcerative colitis 9.8
30 colitis 9.8
31 salmonellosis 9.8
32 thrombosis 9.8
33 legionnaires' disease 9.8
34 strongyloidiasis 9.8
35 xanthogranulomatous pyelonephritis 9.8
36 adenocarcinoma 9.8
37 bronchitis 9.8
38 esophageal cancer 9.6
39 hernia, hiatus 9.6
40 systemic lupus erythematosus 9.6
41 pemphigus vulgaris, familial 9.6
42 tetralogy of fallot 9.6
43 lymphoma, hodgkin, classic 9.6
44 ciliary dyskinesia, primary, 1 9.6
45 myasthenia gravis 9.6
46 asthma 9.6
47 patent ductus arteriosus 1 9.6
48 lung cancer susceptibility 3 9.6
49 arthritis 9.6
50 chronic granulomatous disease 9.6

Comorbidity relations with Lung Abscess via Phenotypic Disease Network (PDN):


Bronchiectasis Bronchitis
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Postinflammatory Pulmonary Fibrosis
Protein-Energy Malnutrition Respiratory Failure

Graphical network of the top 20 diseases related to Lung Abscess:



Diseases related to Lung Abscess
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Symptoms & Phenotypes for Lung Abscess

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UMLS symptoms related to Lung Abscess:


hemoptysis
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Drugs & Therapeutics for Lung Abscess

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Drugs for Lung Abscess (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Infective Agents Phase 4,Phase 3,Not Applicable
2 Antitubercular Agents Phase 4,Phase 3,Not Applicable
3 Anti-Bacterial Agents Phase 4,Phase 3,Not Applicable
4 Antibiotics, Antitubercular Phase 4,Phase 3,Not Applicable
5
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
6
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
7
Sulbactam Approved Phase 3 68373-14-8
8 Estradiol valerate Approved, Investigational, Vet_approved Phase 3 979-32-8
9
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
10
Polyestradiol phosphate Approved Phase 3 28014-46-2
11
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
12
Ampicillin Approved, Vet_approved Phase 3 69-53-4 6249
13
Tigecycline Approved Phase 3 220620-09-7 5282044
14
Colistin Approved Phase 3 1264-72-8, 1066-17-7 5311054
15
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
16
Meropenem Approved, Investigational Phase 3 119478-56-7 64778 441130
17
Amikacin Approved, Investigational, Vet_approved Phase 3 37517-28-5 37768
18 Contraceptives, Oral, Combined Phase 3
19 Contraceptives, Oral Phase 3
20 Nucleic Acid Synthesis Inhibitors Phase 3
21 Estradiol 3-benzoate Phase 3
22 Norgestimate, ethinyl estradiol drug combination Phase 3
23 Topoisomerase Inhibitors Phase 3
24 Contraceptive Agents Phase 3
25 beta-Lactamase Inhibitors Phase 3
26 Estradiol 17 beta-cypionate Phase 3
27 Fluoroquinolones Phase 3
28 Thienamycins Phase 3
29 Pharmaceutical Solutions Phase 3
30
Sultamicillin Approved, Investigational 76497-13-7
31
Salmon Calcitonin Approved, Investigational Not Applicable 47931-85-1 16129616
32
Calcitonin gene-related peptide Investigational Not Applicable 83652-28-2
33 Bone Density Conservation Agents Not Applicable
34 calcitonin Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
2 BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
3 A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) Completed NCT01970371 Phase 3 plazomicin;colistin;meropenem;tigecycline;antibiotic of Investigator's choice
4 Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia Completed NCT01799993 Phase 3 Amikacin Inhalation Solution (BAY41-6551);Aerosolized Placebo
5 Diagnosis of Invasive Pulmonary Aspergillosis by Direct Lung Tissue Aspergillus Galactomannan Antigen Detection From Aspirate by Ultrasound-guided Fine Needle Aspiration Unknown status NCT01301755
6 Special Use-Result Surveillance of Unasyn-S (Kit) for Intravenous Use - A Surveillance on High-dose (>6 g Daily) Administration ‐ Completed NCT01793688 Sulbactam Sodium/Ampicillin Sodium
7 Procalcitonin Antibiotic Consensus Trial (ProACT) Completed NCT02130986 Not Applicable
8 Viral Testing and Biomarkers to Reduce Antibiotic Use for Respiratory Infections Completed NCT01907659 Not Applicable
9 Biomarkers for Diagnosis of Lung Nodules Recruiting NCT01085864
10 An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care Recruiting NCT03191071 Not Applicable

Search NIH Clinical Center for Lung Abscess

Cochrane evidence based reviews: lung abscess

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Genetic Tests for Lung Abscess

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Anatomical Context for Lung Abscess

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MalaCards organs/tissues related to Lung Abscess:

41
Lung, Skin, Brain, Liver, Kidney, Bone, Heart
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Publications for Lung Abscess

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Articles related to Lung Abscess:

(show top 50) (show all 681)
# Title Authors Year
1
Lung abscess following bronchoscopy due to multidrug-resistant Capnocytophaga sputigena adjacent to lung cancer with high PD-L1 expression. ( 29703650 )
2018
2
Evidence of clinical response and stability of Ceftolozane/Tazobactam used to treat a carbapenem-resistant Pseudomonas Aeruginosa lung abscess on an outpatient antimicrobial program. ( 29471023 )
2018
3
Long-term sequelae after lung abscess in children - Two tertiary centers' experience. ( 29454633 )
2018
4
Pediatric Lung Abscess: Immediate Diagnosis by Point-of-Care Ultrasound. ( 29851922 )
2018
5
Lung abscess caused by <i>Streptococcus pneumoniae</i> serotype 6B. ( 29487787 )
2018
6
Transbronchial drainage using endobronchial ultrasonography with guide sheath for lung abscess: A case report. ( 29768382 )
2018
7
Lung abscess seen on echocardiography. ( 29846549 )
2018
8
An unusual case of lung abscess secondary to round pneumonia caused by recurrent <i>Klebsiella pneumoniae</i> strain and the role of occult metastases tumor. ( 29719793 )
2018
9
Lung abscess or empyema? Taking a closer look. ( 29581405 )
2018
10
Correction: <i>Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides</i>. ( 29555816 )
2018
11
Standard and Novel Additional (Optional) Therapy for Lung Abscess by Drainage Using Bronchoscopic Endobronchial Ultrasonography with a Guide Sheath (EBUS-GS). ( 29984749 )
2018
12
The Transbronchial Drainage of a Lung Abscess Using Endobronchial Ultrasonography with a Modified Guide Sheath. ( 29984758 )
2018
13
Failure of ceftolozane-tazobactam salvage therapy in complicated pneumonia with lung abscess. ( 29988582 )
2018
14
Pulmonary sequestration mimicking lung abscess in old age. ( 30117665 )
2018
15
Burkholderia pseudomallei infection presenting with a lung abscess and osteomyelitis in an adult man: A case report. ( 30170455 )
2018
16
Clinical, Radiological and Bacteriological Profile of Lung Abscess - An Observational Hospital Based Study. ( 30337980 )
2018
17
Sternoclavicular joint osteomyelitis extending to lung abscess complicated by Staphylococcal infective endocarditis. ( 28660126 )
2017
18
A rare case of community acquired serratia lung abscess in a patient with cardiac bronchus. ( 28667656 )
2017
19
A Community-acquired Lung Abscess Attributable to Streptococcus pneumoniae which Extended Directly into the Chest Wall. ( 28049987 )
2017
20
Image Characteristics of Lung Abscess by Convex-Probe Endobronchial Ultrasound. ( 28696970 )
2017
21
Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides. ( 28847872 )
2017
22
Lung Abscess as Delayed Manifestation of Pulmonary Arterial Narrowing After Sleeve Resection. ( 28734443 )
2017
23
Large Lung Abscess with Pulmonary Artery Pseudoaneurysm. ( 28214135 )
2017
24
A case of lung abscess successfully treated by transbronchial drainage using a guide sheath. ( 28361002 )
2017
25
A case of relapsed lung abscess caused by Eubacterium brachy infection following an initial diagnosis of pulmonary actinomycosis. ( 28856090 )
2017
26
Lung Abscess: An Early Complication of Lung Transplantation in a Patient with Cystic Fibrosis. ( 29321838 )
2017
27
Lung Abscess Remains a Life-Threatening Condition in Pediatrics - A Case Report. ( 29967884 )
2017
28
Understanding the Lung Abscess Microbiome: Outcomes of Percutaneous Lung Parenchymal Abscess Drainage with Microbiologic Correlation. ( 28321543 )
2017
29
Primary lung abscess caused by Staphylococcus lugdunensis. ( 28751155 )
2017
30
Predictors of Outcome in Modern Surgery for Lung Abscess. ( 28249343 )
2017
31
Surgery of a nocardia lung abscess presenting as a tension pyopneumothorax. ( 28387128 )
2017
32
Subclavian Artery Pseudoaneurysm Following Lung Abscess in a Child. ( 29243021 )
2017
33
The multistep road to ventilator-associated lung abscess: A retrospective study of S.aureus ventilator-associated pneumonia. ( 29261721 )
2017
34
INVASIVE SALMONELLOSIS PRESENTING AS A LUNG ABSCESS: A CASE REPORT. ( 29644825 )
2017
35
Detection of Fusobacterium nucleatum in two cases of empyema and lung abscess using paromomycin-vancomycin supplemented Brucella HK agar. ( 28034636 )
2016
36
First Case of Lung Abscess due to Salmonella enterica Serovar Abony in an Immunocompetent Adult Patient. ( 27429814 )
2016
37
Double jeopardy - concurrent lung abscess and pleural empyema. ( 27208219 )
2016
38
Mycotic bronchial artery aneurysmal rupture in the early stage of lung abscess: A case report. ( 27326956 )
2016
39
Osteomyelitis and lung abscess due to Aspergillus fumigatus in a chronic granulomatous disease patient. ( 28681028 )
2016
40
Neonatal osteomyelitis of the first rib causing lung abscess. ( 27879302 )
2016
41
Case of a neutrophilic dermatosis involving lung abscess after influenza vaccination. ( 27511432 )
2016
42
Lung abscess from Staphylococcus aureus after varicella infection in a 3-month-old infant. ( 27349422 )
2016
43
Should we be alarmed by a lung abscess? ( 27728641 )
2016
44
Lung Abscess Causing Airway Obstruction Requiring Temporary Tracheobronchial Stenting. ( 27454478 )
2016
45
Hodgkin lymphoma mimicking lung abscess. ( 28007734 )
2016
46
Broncho-biliary fistula secondary to biliary obstruction and lung abscess in a patient with pancreatic neuro-endocrine tumor. ( 26994644 )
2016
47
Lung Abscess: Atypical Presentation of Achalasia. ( 27079347 )
2016
48
Endobronchial Instillation of DNase to Facilitate Bronchoscopic Drainage of a Lung Abscess. ( 26653195 )
2015
49
The Whole Picture. A 23-Year-Old Diabetic Female with Persistent Pneumonia and Chronic Lung Abscess. ( 26317272 )
2015
50
Bronchoscopic drainage of a malignant lung abscess. ( 25887013 )
2015
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Variations for Lung Abscess

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Expression for Lung Abscess

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Search GEO for disease gene expression data for Lung Abscess.
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Pathways for Lung Abscess

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GO Terms for Lung Abscess

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Cellular components related to Lung Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Z disc GO:0030018 8.62 FLNC JPH2
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Sources for Lung Abscess

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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