Lung Acinar Adenocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lung Acinar Adenocarcinoma

MalaCards integrated aliases for Lung Acinar Adenocarcinoma:

Name: Lung Acinar Adenocarcinoma ¹² ¹⁵

Acinar Adenocarcinoma of the Lung ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:6482

NCIt ⁵⁰ C5649

UMLS ⁷⁰ C1332137

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Summaries for Lung Acinar Adenocarcinoma

MalaCards based summary : Lung Acinar Adenocarcinoma, also known as acinar adenocarcinoma of the lung, is related to nipples, supernumerary and vulva adenocarcinoma. An important gene associated with Lung Acinar Adenocarcinoma is TNKS (Tankyrase), and among its related pathways/superpathways is Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds. Affiliated tissues include lung and breast.

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Related Diseases for Lung Acinar Adenocarcinoma

Diseases related to Lung Acinar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)

#	Related Disease	Score	Top Affiliating Genes
1	nipples, supernumerary	9.9	PIP KRT20
2	vulva adenocarcinoma	9.9	PIP KRT20
3	vulvar apocrine adenocarcinoma	9.9	PIP KRT20
4	eyelid carcinoma	9.9	PIP KRT20
5	malignant syringoma	9.9	PIP KRT20
6	anal canal adenocarcinoma	9.8	PIP KRT20
7	gastric diffuse adenocarcinoma	9.8	PIP KRT20
8	eccrine sweat gland cancer	9.8	PIP KRT20
9	sweat gland cancer	9.8	PIP KRT20
10	linitis plastica	9.8	PIP KRT20
11	peritoneal serous adenocarcinoma	9.8	PIP KRT20
12	papillary cystadenocarcinoma	9.8	PIP KRT20
13	breast neuroendocrine neoplasm	9.8	PIP KRT20
14	cherubism	9.8	TNKS AXIN1
15	cystic basal cell carcinoma	9.8	PIP KRT20
16	borst-jadassohn intraepidermal carcinoma	9.8	PIP KRT20
17	paget disease, extramammary	9.8	PIP KRT20
18	anal canal carcinoma	9.8	PIP KRT20
19	signet ring cell adenocarcinoma	9.7	PIP KRT20
20	mammary paget's disease	9.7	PIP KRT20
21	rectum adenocarcinoma	9.7	PIP KRT20
22	arthrogryposis, renal dysfunction, and cholestasis 1	9.6	TNKS AXIN1
23	skin benign neoplasm	9.6	PIP KRT20

Graphical network of the top 20 diseases related to Lung Acinar Adenocarcinoma:

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Symptoms & Phenotypes for Lung Acinar Adenocarcinoma

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Drugs & Therapeutics for Lung Acinar Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Lung Acinar Adenocarcinoma

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Genetic Tests for Lung Acinar Adenocarcinoma

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Anatomical Context for Lung Acinar Adenocarcinoma

MalaCards organs/tissues related to Lung Acinar Adenocarcinoma:

⁴⁰

Lung, Breast

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Publications for Lung Acinar Adenocarcinoma

Articles related to Lung Acinar Adenocarcinoma:

#	Title	Authors	PMID	Year
1	[A Case of Simultaneous Double Cancer with Gastric Metastasis of Breast Cancer and Lung Cancer]. ⁶¹	Maekawa T...Tani M	33468788	2020
2	XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway. ⁶¹	Li C...Zhao J	29805633	2018
3	Inverse correlation between galectin-4 and TTF-1 in lung adenocarcinoma. ⁶¹	Hara K...Yao T	28725929	2017
4	Combined immunohistochemistry of beta-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer. ⁶¹	Ikeda S...Asahara T	16451736	2006
5	Monoclonal-antibodies 5g8 and 2h6 are complementary immunohistochemical markers of lung carcinomas. ⁶¹	Joh K...Aizawa S	21556544	1995

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Genes for Lung Acinar Adenocarcinoma

Genes related to Lung Acinar Adenocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TNKS	Tankyrase	Protein Coding	5.31	DISEASES inferred ¹⁵
2	PIP	Prolactin Induced Protein	Protein Coding	5.1	DISEASES inferred ¹⁵
3	RBM47	RNA Binding Motif Protein 47	Protein Coding	5.06	DISEASES inferred ¹⁵
4	AXIN1	Axin 1	Protein Coding	4.85	DISEASES inferred ¹⁵
5	KRT20	Keratin 20	Protein Coding	4.77	DISEASES inferred ¹⁵
6	LGALS4	Galectin 4	Protein Coding	4.57	DISEASES inferred ¹⁵

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Variations for Lung Acinar Adenocarcinoma

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Expression for Lung Acinar Adenocarcinoma

Search GEO for disease gene expression data for Lung Acinar Adenocarcinoma.

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Pathways for Lung Acinar Adenocarcinoma

Pathways related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds ¹	9.88	TNKS AXIN1

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GO Terms for Lung Acinar Adenocarcinoma

Biological processes related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of canonical Wnt signaling pathway	GO:0090263	8.62	TNKS AXIN1

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Sources for Lung Acinar Adenocarcinoma

¹ BioSystems

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³⁸ LncRNADisease

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⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

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⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

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⁶⁷ SNOMED-CT

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⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia