Lung Acinar Adenocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lung Acinar Adenocarcinoma

MalaCards integrated aliases for Lung Acinar Adenocarcinoma:

Name: Lung Acinar Adenocarcinoma ¹¹ ¹⁴

Acinar Adenocarcinoma of the Lung ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:6482

NCIt ⁴⁹ C5649

UMLS ⁷¹ C1332137

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Summaries for Lung Acinar Adenocarcinoma

MalaCards based summary: Lung Acinar Adenocarcinoma, also known as acinar adenocarcinoma of the lung, is related to li-fraumeni syndrome and osteogenic sarcoma. An important gene associated with Lung Acinar Adenocarcinoma is ZDHHC5 (Zinc Finger DHHC-Type Palmitoyltransferase 5). Affiliated tissues include lung and breast.

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Related Diseases for Lung Acinar Adenocarcinoma

Diseases related to Lung Acinar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	li-fraumeni syndrome	10.0
2	osteogenic sarcoma	10.0
3	lung benign neoplasm	10.0
4	lung papillary adenocarcinoma	9.8	ZDHHC5 NKX2-1

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Symptoms & Phenotypes for Lung Acinar Adenocarcinoma

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Drugs & Therapeutics for Lung Acinar Adenocarcinoma

Search Clinical Trials, NIH Clinical Center for Lung Acinar Adenocarcinoma

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Genetic Tests for Lung Acinar Adenocarcinoma

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Anatomical Context for Lung Acinar Adenocarcinoma

Organs/tissues related to Lung Acinar Adenocarcinoma:

MalaCards : Lung, Breast

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Publications for Lung Acinar Adenocarcinoma

Articles related to Lung Acinar Adenocarcinoma:

#	Title	Authors	PMID	Year
1	Multi-Generational Review of Oncologic Tumors in a Family With TP53 Mutation Presenting With a Pediatric Patient With Osteosarcoma and Lung Acinar Adenocarcinoma. ⁶²	Butt H...Macatangay R	34540492	2021
2	[A Case of Simultaneous Double Cancer with Gastric Metastasis of Breast Cancer and Lung Cancer]. ⁶²	Maekawa T...Tani M	33468788	2020
3	XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway. ⁶²	Li C...Zhao J	29805633	2018
4	Inverse correlation between galectin-4 and TTF-1 in lung adenocarcinoma. ⁶²	Hara K...Yao T	28725929	2017
5	Combined immunohistochemistry of beta-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer. ⁶²	Ikeda S...Asahara T	16451736	2006
6	Monoclonal-antibodies 5g8 and 2h6 are complementary immunohistochemical markers of lung carcinomas. ⁶²	Joh K...Aizawa S	21556544	1995

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Genes for Lung Acinar Adenocarcinoma

Genes related to Lung Acinar Adenocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ZDHHC5	Zinc Finger DHHC-Type Palmitoyltransferase 5	Protein Coding	5.54	DISEASES inferred ¹⁴
2	ZDHHC12	Zinc Finger DHHC-Type Palmitoyltransferase 12	Protein Coding	5.06	DISEASES inferred ¹⁴
3	ZDHHC18	Zinc Finger DHHC-Type Palmitoyltransferase 18	Protein Coding	4.93	DISEASES inferred ¹⁴
4	ZDHHC16	Zinc Finger DHHC-Type Palmitoyltransferase 16	Protein Coding	4.92	DISEASES inferred ¹⁴
5	NKX2-1	NK2 Homeobox 1	Protein Coding	4.77	DISEASES inferred ¹⁴
6	SAC3D1	SAC3 Domain Containing 1	Protein Coding	4.74	DISEASES inferred ¹⁴
7	MTFR2	Mitochondrial Fission Regulator 2	Protein Coding	4.71	DISEASES inferred ¹⁴
8	SLC2A5	Solute Carrier Family 2 Member 5	Protein Coding	4.63	DISEASES inferred ¹⁴
9	ZDHHC14	Zinc Finger DHHC-Type Palmitoyltransferase 14	Protein Coding	4.62	DISEASES inferred ¹⁴
10	ZDHHC23	Zinc Finger DHHC-Type Palmitoyltransferase 23	Protein Coding	4.6	DISEASES inferred ¹⁴

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Variations for Lung Acinar Adenocarcinoma

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Expression for Lung Acinar Adenocarcinoma

Search GEO for disease gene expression data for Lung Acinar Adenocarcinoma.

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Pathways for Lung Acinar Adenocarcinoma

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GO Terms for Lung Acinar Adenocarcinoma

Cellular components related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	endoplasmic reticulum	GO:0005783	9.91	ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
2	Golgi apparatus	GO:0005794	9.85	ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
3	Golgi membrane	GO:0000139	9.56	ZDHHC12 ZDHHC18 ZDHHC23 ZDHHC5
4	membrane	GO:0016021	9.53	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
5	membrane	GO:0016020	9.53	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

Biological processes related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein targeting to membrane	GO:0006612	9.76	ZDHHC23 ZDHHC18 ZDHHC14 ZDHHC12
2	peptidyl-L-cysteine S-palmitoylation	GO:0018230	9.56	ZDHHC23 ZDHHC18 ZDHHC14 ZDHHC12
3	telencephalon development	GO:0021537	9.43	ZDHHC16 NKX2-1
4	protein palmitoylation	GO:0018345	9.4	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

Molecular functions related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	transferase activity	GO:0016740	9.73	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
2	protein-cysteine S-palmitoyltransferase activity	GO:0019706	9.73	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
3	acyltransferase activity	GO:0016746	9.63	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
4	palmitoyltransferase activity	GO:0016409	9.36	ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

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Sources for Lung Acinar Adenocarcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LNG022 MIFTS: 16	Lung Acinar Adenocarcinoma Categories: Cancer diseases, Respiratory diseases	Data Licensing For inquiries, contact: [email protected]
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