MCID: LNG022
MIFTS: 16

Lung Acinar Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases
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Aliases & Classifications for Lung Acinar Adenocarcinoma

MalaCards integrated aliases for Lung Acinar Adenocarcinoma:

Name: Lung Acinar Adenocarcinoma 11 14
Acinar Adenocarcinoma of the Lung 11

Classifications:



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Disease Ontology 11 DOID:6482
NCIt 49 C5649
UMLS 71 C1332137

Summaries for Lung Acinar Adenocarcinoma

MalaCards based summary: Lung Acinar Adenocarcinoma, also known as acinar adenocarcinoma of the lung, is related to li-fraumeni syndrome and osteogenic sarcoma. An important gene associated with Lung Acinar Adenocarcinoma is ZDHHC5 (Zinc Finger DHHC-Type Palmitoyltransferase 5). Affiliated tissues include lung and breast.

Related Diseases for Lung Acinar Adenocarcinoma

Diseases related to Lung Acinar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 li-fraumeni syndrome 10.0
2 osteogenic sarcoma 10.0
3 lung benign neoplasm 10.0
4 lung papillary adenocarcinoma 9.8 ZDHHC5 NKX2-1

Symptoms & Phenotypes for Lung Acinar Adenocarcinoma

Drugs & Therapeutics for Lung Acinar Adenocarcinoma

Search Clinical Trials, NIH Clinical Center for Lung Acinar Adenocarcinoma

Genetic Tests for Lung Acinar Adenocarcinoma

Anatomical Context for Lung Acinar Adenocarcinoma

Organs/tissues related to Lung Acinar Adenocarcinoma:

MalaCards : Lung, Breast

Publications for Lung Acinar Adenocarcinoma

Articles related to Lung Acinar Adenocarcinoma:

# Title Authors PMID Year
1
Multi-Generational Review of Oncologic Tumors in a Family With TP53 Mutation Presenting With a Pediatric Patient With Osteosarcoma and Lung Acinar Adenocarcinoma. 62
34540492 2021
2
[A Case of Simultaneous Double Cancer with Gastric Metastasis of Breast Cancer and Lung Cancer]. 62
33468788 2020
3
XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway. 62
29805633 2018
4
Inverse correlation between galectin-4 and TTF-1 in lung adenocarcinoma. 62
28725929 2017
5
Combined immunohistochemistry of beta-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer. 62
16451736 2006
6
Monoclonal-antibodies 5g8 and 2h6 are complementary immunohistochemical markers of lung carcinomas. 62
21556544 1995

Variations for Lung Acinar Adenocarcinoma

Expression for Lung Acinar Adenocarcinoma

Search GEO for disease gene expression data for Lung Acinar Adenocarcinoma.

Pathways for Lung Acinar Adenocarcinoma

GO Terms for Lung Acinar Adenocarcinoma

Cellular components related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.91 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
2 Golgi apparatus GO:0005794 9.85 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
3 Golgi membrane GO:0000139 9.56 ZDHHC12 ZDHHC18 ZDHHC23 ZDHHC5
4 membrane GO:0016021 9.53 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
5 membrane GO:0016020 9.53 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

Biological processes related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein targeting to membrane GO:0006612 9.76 ZDHHC23 ZDHHC18 ZDHHC14 ZDHHC12
2 peptidyl-L-cysteine S-palmitoylation GO:0018230 9.56 ZDHHC23 ZDHHC18 ZDHHC14 ZDHHC12
3 telencephalon development GO:0021537 9.43 ZDHHC16 NKX2-1
4 protein palmitoylation GO:0018345 9.4 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

Molecular functions related to Lung Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity GO:0016740 9.73 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
2 protein-cysteine S-palmitoyltransferase activity GO:0019706 9.73 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
3 acyltransferase activity GO:0016746 9.63 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12
4 palmitoyltransferase activity GO:0016409 9.36 ZDHHC5 ZDHHC23 ZDHHC18 ZDHHC16 ZDHHC14 ZDHHC12

Sources for Lung Acinar Adenocarcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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