LNCR1
MCID: LNG109
MIFTS: 26

Lung Cancer Susceptibility 1 (LNCR1)

Categories: Cancer diseases, Rare diseases, Respiratory diseases
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Aliases & Classifications for Lung Cancer Susceptibility 1

MalaCards integrated aliases for Lung Cancer Susceptibility 1:

Name: Lung Cancer Susceptibility 1 57 71
Lung Cancer Susceptibility 57 12 75
Lncr1 57

Classifications:



External Ids:

OMIM® 57 608935
UMLS 71 C1837089

Summaries for Lung Cancer Susceptibility 1

MalaCards based summary: Lung Cancer Susceptibility 1, also known as lung cancer susceptibility, is related to high grade glioma and lung cancer susceptibility 3. An important gene associated with Lung Cancer Susceptibility 1 is LNCR1 (Lung Cancer 1). Affiliated tissues include lung, myeloid and endothelial.

Wikipedia: 75 Lung cancer susceptibility tests suggest the probability or susceptibility an individual may have of... more...

More information from OMIM: 608935

Related Diseases for Lung Cancer Susceptibility 1

Diseases in the Lung Cancer Susceptibility 3 family:

Lung Cancer Susceptibility 1 Lung Cancer Susceptibility 4
Lung Cancer Susceptibility 5

Diseases related to Lung Cancer Susceptibility 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 high grade glioma 30.9 LNCR3 LNCR1
2 lung cancer susceptibility 3 11.7
3 lung cancer susceptibility 5 11.5
4 lung cancer 11.5
5 smoking as a quantitative trait locus 3 11.5
6 lung cancer susceptibility 4 11.4
7 small cell cancer of the lung 10.5
8 tobacco addiction 10.3
9 lung squamous cell carcinoma 10.3
10 squamous cell carcinoma 10.3
11 small cell carcinoma 10.2
12 adenocarcinoma 10.2
13 lung benign neoplasm 10.2
14 ataxia-telangiectasia 10.2
15 xeroderma pigmentosum, variant type 10.2
16 tumor suppressor gene on chromosome 11 10.2
17 telangiectasis 10.1
18 cleft lip 10.1
19 cleft lip/palate 10.1
20 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.0
21 pulmonary disease, chronic obstructive 10.0
22 bap1 tumor predisposition syndrome 10.0
23 inherited cancer-predisposing syndrome 10.0
24 leukemia, acute lymphoblastic 9.9
25 leukemia 9.9
26 hematologic cancer 9.9
27 t-cell acute lymphoblastic leukemia 9.9
28 precursor t-cell acute lymphoblastic leukemia 9.9
29 aryl hydrocarbon hydroxylase inducibility 9.9
30 cataract 4, multiple types 9.9
31 exostoses, multiple, type ii 9.9
32 oculodentodigital dysplasia 9.9
33 inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 1 9.9
34 down syndrome 9.9
35 adrenocortical carcinoma, hereditary 9.9
36 neuraminidase deficiency 9.9
37 squamous cell carcinoma, head and neck 9.9
38 xeroderma pigmentosum, complementation group a 9.9
39 xeroderma pigmentosum, complementation group c 9.9
40 xeroderma pigmentosum, complementation group d 9.9
41 fanconi anemia, complementation group b 9.9
42 taqi polymorphism 9.9
43 retinitis pigmentosa 11 9.9
44 hyperinsulinemic hypoglycemia, familial, 2 9.9
45 nephronophthisis 4 9.9
46 nasopharyngeal carcinoma 9.9
47 acetyl-coa acetyltransferase-2 deficiency 9.9
48 leptin deficiency or dysfunction 9.9
49 inclusion body myopathy with early-onset paget disease of bone with or without frontotemporal dementia 1 9.9
50 silicosis 9.9

Graphical network of the top 20 diseases related to Lung Cancer Susceptibility 1:



Diseases related to Lung Cancer Susceptibility 1

Symptoms & Phenotypes for Lung Cancer Susceptibility 1

Clinical features from OMIM®:

608935 (Updated 08-Dec-2022)

Drugs & Therapeutics for Lung Cancer Susceptibility 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Correlation Between Lung Cancer Susceptibility, Drug Response and Genetic Polymorphism Unknown status NCT01280448

Search NIH Clinical Center for Lung Cancer Susceptibility 1

Genetic Tests for Lung Cancer Susceptibility 1

Anatomical Context for Lung Cancer Susceptibility 1

Organs/tissues related to Lung Cancer Susceptibility 1:

MalaCards : Lung, Myeloid, Endothelial, Colon, Breast, Testis, Liver

Publications for Lung Cancer Susceptibility 1

Articles related to Lung Cancer Susceptibility 1:

(show top 50) (show all 692)
# Title Authors PMID Year
1
A major lung cancer susceptibility locus maps to chromosome 6q23-25. 62 57
15272417 2004
2
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. 57
19946270 2010
3
Varied manifestations of a familial lymphoproliferative disorder. 57
806230 1975
4
Familial aggregation of lung cancer in humans. 57
13985327 1963
5
Impact of GTF2H1 and RAD54L2 polymorphisms on the risk of lung cancer in the Chinese Han population. 62
36384536 2022
6
Synergistic polymorphic interactions of phase II metabolizing genes and their association toward lung cancer susceptibility in North Indians. 62
36251537 2022
7
Determining Association between Lung Cancer Mortality Worldwide and Risk Factors Using Fuzzy Inference Modeling and Random Forest Modeling. 62
36361041 2022
8
A Novel apaQTL-SNP for the Modification of Non-Small-Cell Lung Cancer Susceptibility across Histological Subtypes. 62
36358727 2022
9
[Association of CDH1, FANCB and APC Gene Polymorphisms 
with Lung Cancer Susceptibility in Chinese Population]. 62
36172730 2022
10
DNA repair in lung cancer: a large-scale quantitative analysis for polymorphisms in DNA repairing pathway genes and lung cancer susceptibility. 62
35984915 2022
11
Association between long non-coding RNA HOTAIR polymorphism and lung cancer risk: A systematic review and meta-analysis. 62
35837044 2022
12
A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians. 62
35500836 2022
13
Lung cancer susceptibility beyond smoking history: opportunities and challenges. 62
35958329 2022
14
Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. 62
35502931 2022
15
Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk. 62
35773316 2022
16
Single nucleotide polymorphisms in FOXP1 and RORA of the lymphocyte activation-related pathway affect survival of lung cancer patients. 62
35693292 2022
17
Association of Interleukin-8 Promoter Genotypes With Taiwan Lung Cancer Risk. 62
35220213 2022
18
The Association Between Cyclooxygenase-2 -1195G/A (rs689466) Gene Polymorphism and the Clinicopathology of Lung Cancer in the Japanese Population: A Case-Controlled Study. 62
35450217 2022
19
Potential Impact of Cancer Susceptibility Genes on Lung Cancer Metastasis. 62
35479964 2022
20
MALAT1 Polymorphisms and Lung Cancer Susceptibility in a Chinese Northeast Han Population. 62
35928715 2022
21
A Germline Mutation in ATR Is Associated With Lung Adenocarcinoma in Asian Patients. 62
35712480 2022
22
Association of NAT-2 gene polymorphisms toward lung cancer susceptibility and prognosis in North Indian patients treated with platinum-based chemotherapy. 62
34911343 2022
23
Clinical Value Screening, Prognostic Significance, and Key Gene Identification of TrkB in Laryngeal Carcinoma. 62
36033826 2022
24
Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer. 62
35101137 2022
25
Identification of Genetic Variants Associated with Sex-Specific Lung-Cancer Risk. 62
34945000 2021
26
Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy. 62
34672683 2021
27
Lung cancer is also a hereditary disease. 62
34670806 2021
28
Association of TIMP-2 Rs8179090 Genotypes With Lung Cancer Risk in Taiwan. 62
34732411 2021
29
Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival. 62
33651148 2021
30
Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with nonsmall cell lung cancer survival. 62
34058013 2021
31
The relevance analysis of GSTP1 rs1695 and lung cancer in the Chinese Han population. 62
34596453 2021
32
Interleukin polymorphisms and protein levels associated with lung cancer susceptibility and phenotypes. 62
34219580 2021
33
The shared genetic architecture between epidemiological and behavioral traits with lung cancer. 62
34475455 2021
34
Cannabis Use, Pulmonary Function, and Lung Cancer Susceptibility: A Mendelian Randomization Study. 62
33852959 2021
35
Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients. 62
33400994 2021
36
DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility. 62
33939316 2021
37
Association between p73 G4C14-to-A4T14 polymorphism and lung cancer risk: A systematic review and meta-analysis. 62
33484055 2021
38
Influence of CMTM8 polymorphisms on lung cancer susceptibility in the Chinese Han population. 62
33395025 2021
39
Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients. 62
34052967 2021
40
Association between NEAT1 polymorphism and the risk of lung cancer: A protocol for systematic review and meta-analysis. 62
33879681 2021
41
Genetic Variants of CLEC4E and BIRC3 in Damage-Associated Molecular Patterns-Related Pathway Genes Predict Non-Small Cell Lung Cancer Survival. 62
34692492 2021
42
Genetic variants of DOCK2, EPHB1 and VAV2 in the natural killer cell-related pathway are associated with non-small cell lung cancer survival. 62
34094683 2021
43
Exploration of Lung Cancer-Related Genetic Factors via Mendelian Randomization Method Based on Genomic and Transcriptomic Summarized Data. 62
34938740 2021
44
The association study between CYP24A1 gene polymorphisms and risk of liver, lung and gastric cancer in a Chinese population. 62
33065483 2020
45
Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis. 62
33327254 2020
46
Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis. 62
33256112 2020
47
Association between miRNA-146a polymorphism and lung cancer susceptibility: A meta-analysis involving 6506 cases and 6576 controls. 62
32640303 2020
48
Polymorphisms in Neuronal Growth Regulator 1 and Otoancorin Alternate the Susceptibility to Lung Cancer in Chinese Nonsmoking Females. 62
32552051 2020
49
Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer. 62
32072637 2020
50
Interaction between common variants of MDM2 and PPP1R13L and CD3EAP and TP53 SNPs in relation to lung cancer risk among Chinese. 62
32953734 2020

Variations for Lung Cancer Susceptibility 1

Expression for Lung Cancer Susceptibility 1

Search GEO for disease gene expression data for Lung Cancer Susceptibility 1.

Pathways for Lung Cancer Susceptibility 1

GO Terms for Lung Cancer Susceptibility 1

Sources for Lung Cancer Susceptibility 1

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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