MCID: LNG036
MIFTS: 26

Lung Leiomyoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Lung Leiomyoma

MalaCards integrated aliases for Lung Leiomyoma:

Name: Lung Leiomyoma 12 15
Pulmonary Leiomyoma 12
Leiomyoma of Lung 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5136
NCIt 51 C5660
UMLS 74 C1334447

Summaries for Lung Leiomyoma

Disease Ontology : 12 A lung benign neoplasm that derives from some smooth muscle cell.

MalaCards based summary : Lung Leiomyoma, also known as pulmonary leiomyoma, is related to leiomyoma and myoma. An important gene associated with Lung Leiomyoma is MIR221 (MicroRNA 221), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Signaling by ERBB4. Affiliated tissues include lung and smooth muscle.

Related Diseases for Lung Leiomyoma

Diseases related to Lung Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 29.6 ESR1 PGR
2 myoma 10.0 ESR1 PGR
3 vestibular gland benign neoplasm 10.0 ESR1 PGR
4 bartholin's gland adenoma 10.0 ESR1 PGR
5 vulvar syringoma 10.0 ESR1 PGR
6 glassy cell carcinoma of the cervix 10.0 ESR1 PGR
7 vulvar benign neoplasm 10.0 ESR1 PGR
8 trigonitis 10.0 ESR1 PGR
9 vulvar leiomyoma 10.0 ESR1 PGR
10 predominantly cortical thymoma 10.0 ESR1 PGR
11 breast medullary carcinoma 10.0 ESR1 PGR
12 breast scirrhous carcinoma 10.0 ESR1 PGR
13 bartholin's gland benign neoplasm 10.0 ESR1 PGR
14 oncocytic breast carcinoma 10.0 ESR1 PGR
15 progesterone-receptor positive breast cancer 10.0 ESR1 PGR
16 progesterone resistance 10.0 ESR1 PGR
17 endometrial squamous cell carcinoma 10.0 ESR1 PGR
18 cribriform carcinoma 10.0 ESR1 PGR
19 endometrial mucinous adenocarcinoma 10.0 ESR1 PGR
20 adenoid basal cell carcinoma 9.9 ESR1 PGR
21 apocrine adenocarcinoma 9.9 ESR1 PGR
22 peritoneal benign neoplasm 9.9 ESR1 PGR
23 gender identity disorder 9.9 ESR1 PGR
24 deep angioma 9.9 ESR1 PGR
25 diffuse peritoneal leiomyomatosis 9.9 ESR1 PGR
26 leiomyomatosis 9.9 ESR1 PGR
27 synchronous bilateral breast carcinoma 9.9 ESR1 PGR
28 breast adenoid cystic carcinoma 9.9 ESR1 PGR
29 female reproductive endometrioid cancer 9.9 ESR1 PGR
30 cervical carcinosarcoma 9.9 ESR1 PGR
31 estrogen excess 9.9 ESR1 PGR
32 intramuscular hemangioma 9.9 ESR1 PGR
33 glycogen-rich clear cell breast carcinoma 9.9 ESR1 PGR
34 mammographic density 9.9 ESR1 PGR
35 cervical clear cell adenocarcinoma 9.9 ESR1 PGR
36 retinitis pigmentosa 47 9.9 ESR1 PGR
37 inflammatory breast carcinoma 9.9 ESR1 PGR
38 retinitis pigmentosa 20 9.9 ESR1 PGR
39 adenosarcoma 9.9 ESR1 PGR
40 luminal breast carcinoma 9.9 ESR1 PGR
41 endometriosis of ovary 9.9 ESR1 PGR
42 endometriosis 9.9 ESR1 PGR
43 breast benign neoplasm 9.9 ESR1 PGR
44 thoracic benign neoplasm 9.9 ESR1 PGR
45 uterine corpus cancer 9.9 ESR1 PGR
46 lipid-rich carcinoma 9.9 ESR1 PGR
47 smooth muscle tumor 9.9 ESR1 PGR
48 uterine benign neoplasm 9.9 ESR1 PGR
49 endometritis 9.9 ESR1 PGR
50 prostatic hypertrophy 9.9 ESR1 PGR

Graphical network of the top 20 diseases related to Lung Leiomyoma:



Diseases related to Lung Leiomyoma

Symptoms & Phenotypes for Lung Leiomyoma

Drugs & Therapeutics for Lung Leiomyoma

Search Clinical Trials , NIH Clinical Center for Lung Leiomyoma

Genetic Tests for Lung Leiomyoma

Anatomical Context for Lung Leiomyoma

MalaCards organs/tissues related to Lung Leiomyoma:

42
Lung, Smooth Muscle

Publications for Lung Leiomyoma

Articles related to Lung Leiomyoma:

# Title Authors Year
1
Sterile Bronchopleural Fistula Following Surgical Removal of Primary Lung Leiomyoma Inducing Secondary Hypertrophic Osteoarthropathy. ( 29519996 )
2018
2
Right middle lobectomy for a primary pulmonary leiomyoma: a case report. ( 20184689 )
2009
3
Pulmonary leiomyoma--a case report. ( 8128743 )
1993
4
Pedunculated pulmonary leiomyoma with large cyst formation. ( 8239825 )
1993
5
Pulmonary leiomyoma. ( 4826252 )
1974
6
Pulmonary leiomyoma. ( 18730327 )
1970
7
Pulmonary leiomyoma. ( 5362909 )
1969

Variations for Lung Leiomyoma

Expression for Lung Leiomyoma

Search GEO for disease gene expression data for Lung Leiomyoma.

Pathways for Lung Leiomyoma

Pathways related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.4 ESR1 PGR
2
Show member pathways
10.99 ESR1 PGR
3
Show member pathways
10.58 ESR1 PGR

GO Terms for Lung Leiomyoma

Biological processes related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.32 ESR1 PGR
2 transcription initiation from RNA polymerase II promoter GO:0006367 9.16 ESR1 PGR
3 transcription, DNA-templated GO:0006351 8.96 ESR1
4 positive regulation of protein kinase B signaling GO:0051897 8.96 ESR1 MIR221
5 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.26 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
3 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
4 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Lung Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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