MCID: LNG036
MIFTS: 23

Lung Leiomyoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Lung Leiomyoma

MalaCards integrated aliases for Lung Leiomyoma:

Name: Lung Leiomyoma 12 15
Pulmonary Leiomyoma 12
Leiomyoma of Lung 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5136
NCIt 50 C5660
SNOMED-CT 68 707374005
UMLS 73 C1334447

Summaries for Lung Leiomyoma

MalaCards based summary : Lung Leiomyoma, also known as pulmonary leiomyoma, is related to angiomyolipoma and leiomyoma. An important gene associated with Lung Leiomyoma is MIR221 (MicroRNA 221
Benign metastasizing leiomyomas are indeed most likely benign lesions, and up-regulation of miR-221 expression is an accurate way to differentiate leiomyosarcoma from benign metastasizing leiomyoma.), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Signaling by ERBB4. Affiliated tissues include lung.

Related Diseases for Lung Leiomyoma

Diseases related to Lung Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 angiomyolipoma 29.2 ESR1 PGR
2 leiomyoma 28.9 ESR1 PGR
3 vulvar syringoma 9.9 ESR1 PGR
4 vestibular gland benign neoplasm 9.9 ESR1 PGR
5 bartholin's gland adenoma 9.9 ESR1 PGR
6 glassy cell carcinoma of the cervix 9.9 ESR1 PGR
7 vulvar benign neoplasm 9.9 ESR1 PGR
8 trigonitis 9.9 ESR1 PGR
9 vulvar leiomyoma 9.9 ESR1 PGR
10 predominantly cortical thymoma 9.9 ESR1 PGR
11 breast medullary carcinoma 9.9 ESR1 PGR
12 breast scirrhous carcinoma 9.9 ESR1 PGR
13 progesterone resistance 9.9 ESR1 PGR
14 progesterone-receptor positive breast cancer 9.9 ESR1 PGR
15 cribriform carcinoma 9.9 ESR1 PGR
16 oncocytic breast carcinoma 9.9 ESR1 PGR
17 endometrial squamous cell carcinoma 9.9 ESR1 PGR
18 gastric signet ring cell adenocarcinoma 9.9 ESR1 PGR
19 endometrial mucinous adenocarcinoma 9.9 ESR1 PGR
20 adenoid basal cell carcinoma 9.9 ESR1 PGR
21 apocrine adenocarcinoma 9.9 ESR1 PGR
22 gender identity disorder 9.9 ESR1 PGR
23 bartholin's gland benign neoplasm 9.9 ESR1 PGR
24 deep angioma 9.9 ESR1 PGR
25 synchronous bilateral breast carcinoma 9.9 ESR1 PGR
26 breast adenoid cystic carcinoma 9.9 ESR1 PGR
27 cervical carcinosarcoma 9.9 ESR1 PGR
28 estrogen excess 9.9 ESR1 PGR
29 intramuscular hemangioma 9.9 ESR1 PGR
30 glycogen-rich clear cell breast carcinoma 9.9 ESR1 PGR
31 mammographic density 9.9 ESR1 PGR
32 retinitis pigmentosa 47 9.9 ESR1 PGR
33 uterine corpus cancer 9.9 ESR1 PGR
34 adenomyosis 9.9 ESR1 PGR
35 retinitis pigmentosa 20 9.9 ESR1 PGR
36 luminal breast carcinoma 9.9 ESR1 PGR
37 adenosarcoma 9.9 ESR1 PGR
38 cervical clear cell adenocarcinoma 9.9 ESR1 PGR
39 breast benign neoplasm 9.9 ESR1 PGR
40 thoracic benign neoplasm 9.9 ESR1 PGR
41 endometriosis of ovary 9.9 ESR1 PGR
42 inflammatory breast carcinoma 9.9 ESR1 PGR
43 mixed cell type cancer 9.9 ESR1 PGR
44 lipid-rich carcinoma 9.9 ESR1 PGR
45 uterine benign neoplasm 9.9 ESR1 PGR
46 reproductive organ benign neoplasm 9.9 ESR1 PGR
47 smooth muscle tumor 9.9 ESR1 PGR
48 pancreatic mucinous cystadenoma 9.9 ESR1 PGR
49 endometritis 9.9 ESR1 PGR
50 prostatic hypertrophy 9.8 ESR1 PGR

Graphical network of the top 20 diseases related to Lung Leiomyoma:



Diseases related to Lung Leiomyoma

Symptoms & Phenotypes for Lung Leiomyoma

Drugs & Therapeutics for Lung Leiomyoma

Search Clinical Trials , NIH Clinical Center for Lung Leiomyoma

Genetic Tests for Lung Leiomyoma

Anatomical Context for Lung Leiomyoma

MalaCards organs/tissues related to Lung Leiomyoma:

41
Lung

Publications for Lung Leiomyoma

Articles related to Lung Leiomyoma:

# Title Authors Year
1
Sterile Bronchopleural Fistula Following Surgical Removal of Primary Lung Leiomyoma Inducing Secondary Hypertrophic Osteoarthropathy. ( 29519996 )
2018
2
(P016) Bilateral Giant Renal Angiomyolipomas and Lung Leiomyomas Associated With Tuberous Sclerosis: A Case Report. ( 27083655 )
2016

Variations for Lung Leiomyoma

Expression for Lung Leiomyoma

Search GEO for disease gene expression data for Lung Leiomyoma.

Pathways for Lung Leiomyoma

Pathways related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.4 ESR1 PGR
2
Show member pathways
10.99 ESR1 PGR
3
Show member pathways
10.58 ESR1 PGR

GO Terms for Lung Leiomyoma

Biological processes related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.26 ESR1 PGR
2 transcription initiation from RNA polymerase II promoter GO:0006367 9.16 ESR1 PGR
3 positive regulation of protein kinase B signaling GO:0051897 8.96 ESR1 MIR221
4 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Lung Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.26 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
3 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
4 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Lung Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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