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MCID: LNG023
MIFTS: 30

Lung Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Lung Leiomyosarcoma

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MalaCards integrated aliases for Lung Leiomyosarcoma:

Name: Lung Leiomyosarcoma 12 15 71
Pulmonary Leiomyosarcoma 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Muscle diseases Respiratory diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5265
NCIt 50 C5667
UMLS 71 C1334448
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Summaries for Lung Leiomyosarcoma

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Disease Ontology : 12 A leiomyosarcoma and sarcoma of lung that is located in the lung.

MalaCards based summary : Lung Leiomyosarcoma, also known as pulmonary leiomyosarcoma, is related to leiomyosarcoma and pulmonary vein leiomyosarcoma. An important gene associated with Lung Leiomyosarcoma is CALB2 (Calbindin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Cytoskeletal Signaling. Affiliated tissues include lung, smooth muscle and myeloid.

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Related Diseases for Lung Leiomyosarcoma

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Diseases related to Lung Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 500)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 30.3 MYOG KIT CHEK2
2 pulmonary vein leiomyosarcoma 30.3 CD34 CALD1
3 pulmonary artery leiomyosarcoma 30.1 KRT7 CD34
4 trachea carcinoma 30.1 KRT7 KIT
5 retroperitoneal leiomyosarcoma 30.1 KIT CD34 CALD1
6 lung sarcoma 29.7 NKX2-1 NAPSA CD34 CALB2
7 mesenchymal cell neoplasm 29.7 MYOG KIT CD34 CALD1
8 glomus tumor 29.6 SYP KIT CD34 CALD1 CALB2
9 angiosarcoma 29.4 MYOG KRT7 KIT CD34 CALB2
10 hemangiopericytoma, malignant 29.3 SYP MYOG KIT CD34 CALD1
11 rhabdomyosarcoma 29.2 SYP MYOG KRT7 KIT CHEK2
12 lung benign neoplasm 29.1 SYP NKX2-1 KRT7 KRT20
13 ovarian melanoma 10.4 CALD1 CALB2
14 intravascular angioleiomyoma 10.4 CD34 CALD1
15 breast myofibroblastoma 10.4 CD34 CALD1
16 spindle cell thymoma 10.4 KRT5 CALB2
17 pacinian tumor 10.4 CD34 CALB2
18 kidney hemangiopericytoma 10.4 CD34 CALB2
19 apocrine adenocarcinoma 10.4 KRT7 KRT5
20 spermatic cord cancer 10.4 KRT5 CD34
21 ovarian fibrothecoma 10.4 KIT CALB2
22 urethra leiomyoma 10.4 KIT CALD1
23 spinal cord sarcoma 10.4 KIT CD34
24 gallbladder leiomyoma 10.4 KIT CD34
25 lymphoepithelioma-like thymic carcinoma 10.4 KRT5 KIT
26 ureter squamous cell carcinoma 10.4 KRT7 KRT5
27 intravenous leiomyomatosis 10.4 CD34 CALD1
28 rete testis neoplasm 10.4 KRT7 CALB2
29 small intestine leiomyosarcoma 10.4 KIT CD34
30 rete testis adenocarcinoma 10.4 KRT7 CALB2
31 central nervous system fibrosarcoma 10.3 KRT7 CD34
32 inverted transitional papilloma 10.3 KRT7 KRT5
33 bartholin's gland disease 10.3 KRT7 CALB2
34 gastric liposarcoma 10.3 KIT CD34
35 cervical mucinous adenocarcinoma 10.3 KRT7 CALD1
36 ceruminoma 10.3 KRT7 KRT5
37 congenital granular cell tumor 10.3 CD34 CALD1
38 gastric leiomyoma 10.3 KIT CALD1
39 cutaneous leiomyosarcoma 10.3 CD34 CALD1
40 vulvar leiomyoma 10.3 CD34 CALD1
41 infiltrating angiolipoma 10.3 CD34 CALD1
42 angiolipoma 10.3 CD34 CALD1
43 microinvasive cervical squamous cell carcinoma 10.3 KRT7 KRT5
44 intravascular fasciitis 10.3 CD34 CALD1
45 retroperitoneal hemangiopericytoma 10.3 KIT CD34
46 epididymal neoplasm 10.3 KRT7 CALB2
47 benign breast adenomyoepithelioma 10.3 KRT7 KRT5
48 extraosseous osteosarcoma 10.3 CD34 CALD1
49 nephrogenic adenofibroma 10.3 KRT7 CD34
50 lung clear cell carcinoma 10.3 KRT7 KRT5

Graphical network of the top 20 diseases related to Lung Leiomyosarcoma:



Diseases related to Lung Leiomyosarcoma
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Symptoms & Phenotypes for Lung Leiomyosarcoma

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Drugs & Therapeutics for Lung Leiomyosarcoma

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Search Clinical Trials , NIH Clinical Center for Lung Leiomyosarcoma

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Genetic Tests for Lung Leiomyosarcoma

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Anatomical Context for Lung Leiomyosarcoma

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The Foundational Model of Anatomy Ontology organs/tissues related to Lung Leiomyosarcoma:

19
Lung

MalaCards organs/tissues related to Lung Leiomyosarcoma:

40
Lung, Smooth Muscle, Myeloid
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Publications for Lung Leiomyosarcoma

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Articles related to Lung Leiomyosarcoma:

(show top 50) (show all 82)
# Title Authors PMID Year
1
A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy. 61
31152263 2019
2
[Li-Fraumeni syndrome]. 61
30730202 2019
3
Primary pulmonary leiomyosarcoma-case report of a rare aggressive neoplasm. 61
33060989 2019
4
A case of primary pulmonary leiomyosarcoma. 61
31193966 2019
5
[Surgical Treatment of Refractory Chest Tumors Assisted 
by Cardiopulmonary Bypass]. 61
29587914 2018
6
Pulmonary artery leiomyosarcoma: A clinical dilemma. 61
29487255 2018
7
Primary pulmonary leiomyosarcoma: A population-based study. 61
29413053 2018
8
Primary lung sarcoma treated with stereotactic ablative radiotherapy: a case report. 61
28740403 2017
9
Primary pulmonary leiomyosarcoma: A case report. 61
26998080 2016
10
Primary pulmonary leiomyosarcoma with invasion of the pulmonary vein-A case report. 61
26745312 2016
11
Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review. 61
26275258 2015
12
When a pulmonary embolism is not a pulmonary embolism: a rare case of primary pulmonary leiomyosarcoma. 61
26653696 2015
13
Gastrointestinal bleeding in lung leiomyosarcoma history: report of a case. 61
25276388 2014
14
Primary pulmonary leiomyosarcoma. 61
24263234 2014
15
Pulmonary leiomyosarcoma mimicking glomus tumor at first biopsy and surgically treated with isolated left main bronchus resection: rare clinical documentation. 61
23636708 2013
16
Metastatic leiomyosarcoma of the intrapancreatic bile duct. 61
23323239 2013
17
Primary pulmonary leiomyosarcoma -- a case report. 61
22410283 2012
18
[The diagnostic challenge of a rare pulmonary neoplasm]. 61
23079254 2012
19
High-grade primary pulmonary leiomyosarcoma. 61
26761258 2011
20
A case of Epstein-Barr virus-associated pulmonary leiomyosarcoma arising five yr after a pediatric renal transplant. 61
20456653 2011
21
Choroidal metastasis from primary pulmonary leiomyosarcoma. 61
22452689 2011
22
Therapy-related acute myeloid leukemia in a primary pulmonary leiomyosarcoma patient with skin metastasis. 61
23467305 2011
23
Pulmonary leiomyosarcoma metastatic to the thyroid gland: case report and review of the literature. 61
21784409 2011
24
[Primary giant pulmonary leiomyosarcoma]. 61
21695991 2011
25
[A case of primary pulmonary leiomyosarcoma with multiple nodular lesions in the lungs]. 61
21485148 2011
26
[A case of primary pulmonary leiomyosarcoma showing rapid growth and fatal outcome]. 61
21066859 2010
27
[Pulmonary leiomyosarcoma treated with surgery; report of a case]. 61
20533747 2010
28
Diagnosis and management of primary pulmonary leiomyosarcoma. 61
20430913 2010
29
[Primary pulmonary leiomyosarcoma revealed by spontaneous pneumothorax]. 61
19878807 2009
30
Metastatic pulmonary leiomyosarcoma presenting with a long disease-free interval: report of a case. 61
18612791 2008
31
Pulmonary leiomyosarcoma presenting as a pancoast tumor. 61
17673374 2007
32
Contrast-enhanced dynamic magnetic resonance imaging of primary pulmonary leiomyosarcoma. 61
17077604 2006
33
Primary lung leiomyosarcoma detected by bronchoscopy cytology. 61
16078256 2005
34
Intracardiac extension of metastatic pulmonary leiomyosarcoma. 61
16352268 2005
35
[A case of primary pulmonary leiomyosarcoma with history of pneumonia 5 years before]. 61
15168460 2004
36
Epstein-Barr virus-associated pulmonary leiomyosarcoma arising twenty-nine years after renal transplantation. 61
14502177 2003
37
[A case of pulmonary leiomyosarcoma]. 61
12642919 2002
38
Primary pulmonary leiomyosarcoma. Report of a case diagnosed by fine needle aspiration cytology. 61
12365230 2002
39
Pulmonary leiomyosarcoma. 61
12026253 2002
40
Cytological findings of a primary mediastino-pulmonary leiomyosarcoma. Report of a case diagnosed by endoscopic ultrasonography-guided fine needle aspiration. 61
11843945 2001
41
Radiologic findings in primary pulmonary leiomyosarcoma. 61
10798636 2000
42
[Primary leiomyosarcoma of the pulmonary artery--a case report]. 61
10705756 2000
43
[A case of preoperatively diagnosed primary pulmonary leiomyosarcoma]. 61
10707546 1999
44
[Lung leiomyosarcoma 21 years after hysterectomy for uterine leiomyosarcoma: late metastasis?]. 61
10680131 1999
45
Metastatic pulmonary leiomyosarcoma: cytopathologic diagnosis on sputum examination. 61
9557263 1998
46
Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass. 61
9475541 1998
47
Pulmonary leiomyosarcoma. 61
11324500 1997
48
Simultaneous lung and liver resection for primary pulmonary leiomyosarcoma. 61
9097358 1997
49
Pulmonary leiomyosarcoma--report of three cases. 61
9387409 1996
50
Cytology of metastatic leiomyosarcoma. A case report. 61
7484003 1995
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Variations for Lung Leiomyosarcoma

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Expression for Lung Leiomyosarcoma

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Search GEO for disease gene expression data for Lung Leiomyosarcoma.
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Pathways for Lung Leiomyosarcoma

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Pathways related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
NF-kappaB Signaling 4
12.22 KITLG KIT CEACAM5 CD34
2
Cytoskeletal Signaling 4
12.11 KRT7 KRT5 KRT20 CALD1
3
Hematopoietic cell lineage 36
11.54 KITLG KIT CD34
4
Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.41 MYOG KIT CD34
5
C-MYB transcription factor network 1
11.22 KITLG KIT CD34
6
Dendritic Cells Developmental Lineage Pathway 64
11 THBD KIT CD34
7
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
10.99 KITLG KIT CEACAM5 CD34
8
Regulation of KIT signaling 65
10.64 KITLG KIT
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GO Terms for Lung Leiomyosarcoma

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Biological processes related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.33 KRT7 KRT5 KRT20
2 embryonic hemopoiesis GO:0035162 9.26 KITLG KIT
3 negative regulation of blood coagulation GO:0030195 8.96 THBD CD34
4 ectopic germ cell programmed cell death GO:0035234 8.62 KITLG KIT
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Sources for Lung Leiomyosarcoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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