MCID: LNG023
MIFTS: 27

Lung Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases, Respiratory diseases

Aliases & Classifications for Lung Leiomyosarcoma

MalaCards integrated aliases for Lung Leiomyosarcoma:

Name: Lung Leiomyosarcoma 12 15 71
Pulmonary Leiomyosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5265
NCIt 49 C5667
UMLS 71 C1334448

Summaries for Lung Leiomyosarcoma

Disease Ontology : 12 A leiomyosarcoma and sarcoma of lung that is located in the lung.

MalaCards based summary : Lung Leiomyosarcoma, also known as pulmonary leiomyosarcoma, is related to glomus tumor and leiomyosarcoma. An important gene associated with Lung Leiomyosarcoma is CALB2 (Calbindin 2), and among its related pathways/superpathways are Cardiac conduction and Hepatic ABC Transporters. Affiliated tissues include lung, bone and smooth muscle.

Related Diseases for Lung Leiomyosarcoma

Diseases related to Lung Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 glomus tumor 29.4 CALD1 CALB2
2 leiomyosarcoma 10.5
3 rare tumor 10.1
4 liver fibroma 10.1 KRT5 CALB2
5 malignant biphasic mesothelioma 10.1 KRT5 CALB2
6 benign mesothelioma 10.1 KRT5 CALB2
7 pericardium cancer 10.1 KRT5 CALB2
8 nephrogenic adenoma of the urethra 10.0 KRT5 CALB2
9 lung sarcoma 10.0
10 substernal goiter 10.0 KCNK17 KCNK15
11 cystadenofibroma 10.0 KRT5 CALB2
12 apperceptive agnosia 10.0 KCNK17 KCNK15
13 liver leiomyosarcoma 10.0 KRT5 CALB2
14 thymus clear cell carcinoma 10.0 KRT5 CALB2
15 pericardial mesothelioma 10.0 KRT5 CALB2
16 mucinous stomach adenocarcinoma 10.0 KRT5 CALB2
17 ovarian melanoma 10.0 CALD1 CALB2
18 epididymis adenocarcinoma 10.0 KRT5 CALB2
19 epididymis cancer 10.0 KRT5 CALB2
20 peritoneal benign neoplasm 10.0 CALD1 CALB2
21 uterus perivascular epithelioid cell tumor 10.0 CALD1 CALB2
22 malignant spiradenoma 10.0 KRT5 CALB2
23 ovarian endometrioid stromal sarcoma 10.0 CALD1 CALB2
24 heart cancer 10.0 KRT5 CALB2
25 adenomatoid tumor 9.9 KRT5 CALB2
26 peritoneum cancer 9.9 KRT5 CALB2
27 subareolar duct papillomatosis 9.9 KRT5 CALD1
28 nipple benign neoplasm 9.9 KRT5 CALD1
29 colon leiomyosarcoma 9.9 KRT5 CALD1
30 sarcomatoid mesothelioma 9.9 KRT5 CALB2
31 sarcomatoid squamous cell skin carcinoma 9.9 KRT5 CALD1
32 esophagus sarcoma 9.8 KRT5 CALD1
33 endobronchial lipoma 9.8 KRT5 CALD1
34 uterus leiomyosarcoma 9.8 KRT5 CALD1
35 pleural empyema 9.8
36 active peptic ulcer disease 9.8
37 pneumothorax, primary spontaneous 9.8
38 hemangiopericytoma, malignant 9.8
39 leukemia, acute myeloid 9.8
40 pulmonary disease, chronic obstructive 9.8
41 myelodysplastic syndrome 9.8
42 angiosarcoma 9.8
43 respiratory failure 9.8
44 leiomyoma 9.8
45 pneumothorax 9.8
46 rhabdomyosarcoma 9.8
47 mesenchymal cell neoplasm 9.8
48 fibrosarcoma 9.8
49 lung benign neoplasm 9.8
50 trachea carcinoma 9.8

Graphical network of the top 20 diseases related to Lung Leiomyosarcoma:



Diseases related to Lung Leiomyosarcoma

Symptoms & Phenotypes for Lung Leiomyosarcoma

Drugs & Therapeutics for Lung Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Lung Leiomyosarcoma

Genetic Tests for Lung Leiomyosarcoma

Anatomical Context for Lung Leiomyosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Lung Leiomyosarcoma:

19
Lung

MalaCards organs/tissues related to Lung Leiomyosarcoma:

40
Lung, Bone, Smooth Muscle, Liver, Thyroid, Skin, Myeloid

Publications for Lung Leiomyosarcoma

Articles related to Lung Leiomyosarcoma:

(show top 50) (show all 82)
# Title Authors PMID Year
1
A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy. 61
31152263 2019
2
[Li-Fraumeni syndrome]. 61
30730202 2019
3
A case of primary pulmonary leiomyosarcoma. 61
31193966 2019
4
[Surgical Treatment of Refractory Chest Tumors Assisted 
by Cardiopulmonary Bypass]. 61
29587914 2018
5
Pulmonary artery leiomyosarcoma: A clinical dilemma. 61
29487255 2018
6
Primary pulmonary leiomyosarcoma: A population-based study. 61
29413053 2018
7
Primary lung sarcoma treated with stereotactic ablative radiotherapy: a case report. 61
28740403 2017
8
Primary pulmonary leiomyosarcoma: A case report. 61
26998080 2016
9
Primary pulmonary leiomyosarcoma with invasion of the pulmonary vein-A case report. 61
26745312 2016
10
Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review. 61
26275258 2015
11
When a pulmonary embolism is not a pulmonary embolism: a rare case of primary pulmonary leiomyosarcoma. 61
26653696 2015
12
Gastrointestinal bleeding in lung leiomyosarcoma history: report of a case. 61
25276388 2014
13
Primary pulmonary leiomyosarcoma. 61
24263234 2014
14
Pulmonary leiomyosarcoma mimicking glomus tumor at first biopsy and surgically treated with isolated left main bronchus resection: rare clinical documentation. 61
23636708 2013
15
Metastatic leiomyosarcoma of the intrapancreatic bile duct. 61
23323239 2013
16
Primary pulmonary leiomyosarcoma -- a case report. 61
22410283 2012
17
[The diagnostic challenge of a rare pulmonary neoplasm]. 61
23079254 2012
18
High-grade primary pulmonary leiomyosarcoma. 61
26761258 2011
19
A case of Epstein-Barr virus-associated pulmonary leiomyosarcoma arising five yr after a pediatric renal transplant. 61
20456653 2011
20
Therapy-related acute myeloid leukemia in a primary pulmonary leiomyosarcoma patient with skin metastasis. 61
23467305 2011
21
Choroidal metastasis from primary pulmonary leiomyosarcoma. 61
22452689 2011
22
Pulmonary leiomyosarcoma metastatic to the thyroid gland: case report and review of the literature. 61
21784409 2011
23
[A case of primary pulmonary leiomyosarcoma with multiple nodular lesions in the lungs]. 61
21485148 2011
24
[Primary giant pulmonary leiomyosarcoma]. 61
21695991 2011
25
[A case of primary pulmonary leiomyosarcoma showing rapid growth and fatal outcome]. 61
21066859 2010
26
[Pulmonary leiomyosarcoma treated with surgery; report of a case]. 61
20533747 2010
27
Diagnosis and management of primary pulmonary leiomyosarcoma. 61
20430913 2010
28
[Primary pulmonary leiomyosarcoma revealed by spontaneous pneumothorax]. 61
19878807 2009
29
Metastatic pulmonary leiomyosarcoma presenting with a long disease-free interval: report of a case. 61
18612791 2008
30
Pulmonary leiomyosarcoma presenting as a pancoast tumor. 61
17673374 2007
31
Contrast-enhanced dynamic magnetic resonance imaging of primary pulmonary leiomyosarcoma. 61
17077604 2006
32
Primary lung leiomyosarcoma detected by bronchoscopy cytology. 61
16078256 2005
33
Intracardiac extension of metastatic pulmonary leiomyosarcoma. 61
16352268 2005
34
[A case of primary pulmonary leiomyosarcoma with history of pneumonia 5 years before]. 61
15168460 2004
35
Epstein-Barr virus-associated pulmonary leiomyosarcoma arising twenty-nine years after renal transplantation. 61
14502177 2003
36
[A case of pulmonary leiomyosarcoma]. 61
12642919 2002
37
Primary pulmonary leiomyosarcoma. Report of a case diagnosed by fine needle aspiration cytology. 61
12365230 2002
38
Pulmonary leiomyosarcoma. 61
12026253 2002
39
Cytological findings of a primary mediastino-pulmonary leiomyosarcoma. Report of a case diagnosed by endoscopic ultrasonography-guided fine needle aspiration. 61
11843945 2001
40
Radiologic findings in primary pulmonary leiomyosarcoma. 61
10798636 2000
41
[Primary leiomyosarcoma of the pulmonary artery--a case report]. 61
10705756 2000
42
[A case of preoperatively diagnosed primary pulmonary leiomyosarcoma]. 61
10707546 1999
43
[Lung leiomyosarcoma 21 years after hysterectomy for uterine leiomyosarcoma: late metastasis?]. 61
10680131 1999
44
Case report: Pulmonary leiomyosarcoma presenting as a pseudoaneurysm. 61
9833792 1998
45
Metastatic pulmonary leiomyosarcoma: cytopathologic diagnosis on sputum examination. 61
9557263 1998
46
Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass. 61
9475541 1998
47
Pulmonary leiomyosarcoma. 61
11324500 1997
48
Simultaneous lung and liver resection for primary pulmonary leiomyosarcoma. 61
9097358 1997
49
Pulmonary leiomyosarcoma--report of three cases. 61
9387409 1996
50
Cytology of metastatic leiomyosarcoma. A case report. 61
7484003 1995

Variations for Lung Leiomyosarcoma

Expression for Lung Leiomyosarcoma

Search GEO for disease gene expression data for Lung Leiomyosarcoma.

Pathways for Lung Leiomyosarcoma

GO Terms for Lung Leiomyosarcoma

Biological processes related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of ion transmembrane transport GO:0034765 9.26 KCNK17 KCNK15
2 potassium ion transport GO:0006813 9.16 KCNK17 KCNK15
3 potassium ion transmembrane transport GO:0071805 8.96 KCNK17 KCNK15
4 stabilization of membrane potential GO:0030322 8.62 KCNK17 KCNK15

Molecular functions related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 voltage-gated ion channel activity GO:0005244 9.16 KCNK17 KCNK15
2 potassium channel activity GO:0005267 8.96 KCNK17 KCNK15
3 potassium ion leak channel activity GO:0022841 8.62 KCNK17 KCNK15

Sources for Lung Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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