MCID: LNG023
MIFTS: 29

Lung Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases, Respiratory diseases

Aliases & Classifications for Lung Leiomyosarcoma

MalaCards integrated aliases for Lung Leiomyosarcoma:

Name: Lung Leiomyosarcoma 12 15 74
Pulmonary Leiomyosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5265
NCIt 51 C5667
UMLS 74 C1334448

Summaries for Lung Leiomyosarcoma

Disease Ontology : 12 A leiomyosarcoma and sarcoma of lung that is located in the lung.

MalaCards based summary : Lung Leiomyosarcoma, also known as pulmonary leiomyosarcoma, is related to leiomyoma and leukemia, acute myeloid. An important gene associated with Lung Leiomyosarcoma is CHEK2 (Checkpoint Kinase 2), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include lung, liver and the lung, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Lung Leiomyosarcoma

Diseases related to Lung Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 29.6 CD34 KIT
2 leukemia, acute myeloid 28.9 CD34 KIT
3 breast leiomyosarcoma 10.0 CD34 CHEK2
4 leiomyosarcoma 9.9
5 gallbladder leiomyoma 9.9 CD34 KIT
6 liver leiomyoma 9.9 CD34 KIT
7 deep leiomyoma 9.9 CD34 KIT
8 extracutaneous mastocytoma 9.9 CD34 KIT
9 small intestine leiomyosarcoma 9.9 CD34 KIT
10 small intestinal sarcoma 9.9 CD34 KIT
11 gallbladder sarcoma 9.9 CD34 KIT
12 prostate leiomyosarcoma 9.9 CD34 KIT
13 plexiform schwannoma 9.9 CD34 KIT
14 conventional fibrosarcoma 9.9 CD34 KIT
15 peritoneal benign neoplasm 9.9 CD34 KIT
16 diffuse peritoneal leiomyomatosis 9.9 CD34 KIT
17 breast angiosarcoma 9.9 CD34 KIT
18 senile angioma 9.9 CD34 KIT
19 angiomyoma 9.9 CD34 KIT
20 spindle cell liposarcoma 9.9 CD34 KIT
21 mesenchymal cell neoplasm 9.9 CD34 KIT
22 cardiovascular organ benign neoplasm 9.9 CD34 KIT
23 benign perivascular tumor 9.9 CD34 KIT
24 muscle cancer 9.9 CD34 KIT
25 vascular cancer 9.9 CD34 KIT
26 connective tissue cancer 9.9 CD34 KIT
27 neurofibroma 9.8 CD34 KIT
28 leukocyte disease 9.8 CD34 KIT
29 dermatofibrosarcoma protuberans 9.8 CD34 KIT
30 gastrointestinal system cancer 9.8 CD34 KIT
31 acute leukemia 9.8 CD34 KIT
32 bone marrow cancer 9.8 CD34 KIT
33 gastrointestinal stromal tumor 9.8 CD34 KIT
34 myelofibrosis 9.8 CD34 KIT
35 arteriovenous fistula 9.8
36 leukemia 9.8
37 glomus tumor 9.8
38 trachea carcinoma 9.8
39 human immunodeficiency virus infectious disease 9.8
40 myeloid leukemia 9.8
41 pulmonary embolism 9.8
42 myeloma, multiple 9.8 CD34 KIT
43 muscular disease 9.8 CD34 KIT
44 large intestine cancer 9.7 CD34 CHEK2
45 leukemia, chronic myeloid 9.7 CD34 KIT
46 adenoid cystic carcinoma 9.7 CHEK2 KIT
47 hematologic cancer 9.7 CD34 KIT
48 myelodysplastic syndrome 9.5 CD34 CHEK2 KIT

Graphical network of the top 20 diseases related to Lung Leiomyosarcoma:



Diseases related to Lung Leiomyosarcoma

Symptoms & Phenotypes for Lung Leiomyosarcoma

GenomeRNAi Phenotypes related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.35 KIT
2 Decreased substrate adherent cell growth GR00193-A-2 9.35 KIT
3 Decreased substrate adherent cell growth GR00193-A-3 9.35 CHEK2
4 Decreased substrate adherent cell growth GR00193-A-4 9.35 CHEK2 KIT
5 Increased cell viability after pRB stimulation GR00230-A-1 8.62 CHEK2 KIT

MGI Mouse Phenotypes related to Lung Leiomyosarcoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 CD34 CHEK2 KIT

Drugs & Therapeutics for Lung Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Lung Leiomyosarcoma

Genetic Tests for Lung Leiomyosarcoma

Anatomical Context for Lung Leiomyosarcoma

MalaCards organs/tissues related to Lung Leiomyosarcoma:

42
Lung, Liver

The Foundational Model of Anatomy Ontology organs/tissues related to Lung Leiomyosarcoma:

20
The Lung

Publications for Lung Leiomyosarcoma

Articles related to Lung Leiomyosarcoma:

(show all 32)
# Title Authors Year
1
Primary pulmonary leiomyosarcoma: A case report. ( 26998080 )
2016
2
Primary pulmonary leiomyosarcoma with invasion of the pulmonary vein-A case report. ( 26745312 )
2016
3
Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review. ( 26275258 )
2015
4
When a pulmonary embolism is not a pulmonary embolism: a rare case of primary pulmonary leiomyosarcoma. ( 26653696 )
2015
5
Gastrointestinal bleeding in lung leiomyosarcoma history: report of a case. ( 25276388 )
2014
6
High-grade primary pulmonary leiomyosarcoma. ( 26761258 )
2011
7
Metastatic pulmonary leiomyosarcoma presenting with a long disease-free interval: report of a case. ( 18612791 )
2008
8
Contrast-enhanced dynamic magnetic resonance imaging of primary pulmonary leiomyosarcoma. ( 17077604 )
2006
9
Primary lung leiomyosarcoma detected by bronchoscopy cytology. ( 16078256 )
2005
10
Intracardiac extension of metastatic pulmonary leiomyosarcoma. ( 16352268 )
2005
11
Epstein-Barr virus-associated pulmonary leiomyosarcoma arising twenty-nine years after renal transplantation. ( 14502177 )
2003
12
Primary pulmonary leiomyosarcoma. Report of a case diagnosed by fine needle aspiration cytology. ( 12365230 )
2002
13
Pulmonary leiomyosarcoma. ( 12026253 )
2002
14
Cytological findings of a primary mediastino-pulmonary leiomyosarcoma. Report of a case diagnosed by endoscopic ultrasonography-guided fine needle aspiration. ( 11843945 )
2001
15
Radiologic findings in primary pulmonary leiomyosarcoma. ( 10798636 )
2000
16
Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass. ( 9475541 )
1998
17
Case report: Pulmonary leiomyosarcoma presenting as a pseudoaneurysm. ( 9833792 )
1998
18
Pulmonary leiomyosarcoma. ( 11324500 )
1997
19
Simultaneous lung and liver resection for primary pulmonary leiomyosarcoma. ( 9097358 )
1997
20
Pulmonary leiomyosarcoma--report of three cases. ( 9387409 )
1996
21
99mTc(V)-DMSA and 99mTc-MDP uptake and no 67Ga-citrate uptake in a case of primary pulmonary leiomyosarcoma. ( 1327043 )
1992
22
Simultaneous pulmonary leiomyosarcoma and leiomyoma in pediatric HIV infection. ( 1782114 )
1991
23
Pulmonary leiomyosarcoma appearing as a cyst. Report of one case and review of the literature. ( 2413580 )
1985
24
Primary pulmonary leiomyosarcoma with digital clubbing and pleural effusion. Case report. ( 6493180 )
1984
25
Primary pulmonary leiomyosarcoma. Review of the literature and report of a case. ( 6528273 )
1984
26
Primary pulmonary leiomyosarcoma: case report and review of literature. ( 1119863 )
1975
27
Primary pulmonary leiomyosarcoma. Report of 2 cases and review of the literature. ( 4816214 )
1974
28
Pulmonary leiomyosarcoma associated with an arteriovenous fistula. ( 4835091 )
1974
29
Primary pulmonary leiomyosarcoma. Review of the literature and report of one new case. ( 5318907 )
1965
30
Pulmonary leiomyosarcoma; review and report of a case. ( 13487051 )
1958
31
Primary pulmonary leiomyosarcoma. ( 13404915 )
1957
32
Pulmonary leiomyosarcoma in a child. ( 13053337 )
1953

Variations for Lung Leiomyosarcoma

Expression for Lung Leiomyosarcoma

Search GEO for disease gene expression data for Lung Leiomyosarcoma.

Pathways for Lung Leiomyosarcoma

GO Terms for Lung Leiomyosarcoma

Biological processes related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein autophosphorylation GO:0046777 8.96 CHEK2 KIT
2 hemopoiesis GO:0030097 8.62 CD34 KIT

Sources for Lung Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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