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MCID: LNG023
MIFTS: 23

Lung Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Lung Leiomyosarcoma

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MalaCards integrated aliases for Lung Leiomyosarcoma:

Name: Lung Leiomyosarcoma 12 15 73
Pulmonary Leiomyosarcoma 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Muscle diseases Respiratory diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5265
NCIt 50 C5667
UMLS 73 C1334448
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Summaries for Lung Leiomyosarcoma

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Disease Ontology : 12 A leiomyosarcoma and sarcoma of lung that is located in the lung.

MalaCards based summary : Lung Leiomyosarcoma, also known as pulmonary leiomyosarcoma, is related to gallbladder leiomyoma and liver leiomyoma. An important gene associated with Lung Leiomyosarcoma is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include the lung and lung.

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Related Diseases for Lung Leiomyosarcoma

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Diseases related to Lung Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 gallbladder leiomyoma 9.8 CD34 KIT
2 liver leiomyoma 9.8 CD34 KIT
3 deep leiomyoma 9.8 CD34 KIT
4 extracutaneous mastocytoma 9.8 CD34 KIT
5 leiomyosarcoma 9.8
6 small intestine leiomyosarcoma 9.8 CD34 KIT
7 small intestinal sarcoma 9.8 CD34 KIT
8 gallbladder sarcoma 9.8 CD34 KIT
9 prostate leiomyosarcoma 9.8 CD34 KIT
10 diffuse cutaneous mastocytosis 9.8 CD34 KIT
11 sarcomatoid squamous cell skin carcinoma 9.8 CD34 KIT
12 gastric leiomyosarcoma 9.8 CD34 KIT
13 breast angiosarcoma 9.8 CD34 KIT
14 plexiform schwannoma 9.8 CD34 KIT
15 conventional fibrosarcoma 9.8 CD34 KIT
16 senile angioma 9.8 CD34 KIT
17 angiomyoma 9.8 CD34 KIT
18 spindle cell liposarcoma 9.8 CD34 KIT
19 mesenchymal cell neoplasm 9.7 CD34 KIT
20 spindle cell synovial sarcoma 9.7 CD34 KIT
21 muscle cancer 9.7 CD34 KIT
22 connective tissue cancer 9.7 CD34 KIT
23 organ system benign neoplasm 9.7 CD34 KIT
24 leukocyte disease 9.7 CD34 KIT
25 dermatofibrosarcoma protuberans 9.7 CD34 KIT
26 cell type cancer 9.7 CD34 KIT
27 gastrointestinal system cancer 9.6 CD34 KIT
28 leiomyoma 9.6 CD34 KIT
29 acute leukemia 9.6 CD34 KIT
30 bone marrow cancer 9.6 CD34 KIT
31 gastrointestinal stromal tumor 9.6 CD34 KIT
32 myelofibrosis 9.5 CD34 KIT
33 leukemia, chronic myeloid 9.5 CD34 KIT
34 hematologic cancer 9.4 CD34 KIT
35 leukemia, acute myeloid 9.3 CD34 KIT
36 myelodysplastic syndrome 9.2 CD34 KIT
37 ewing sarcoma 9.0 CD34 KIT

Graphical network of the top 20 diseases related to Lung Leiomyosarcoma:



Diseases related to Lung Leiomyosarcoma
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Symptoms & Phenotypes for Lung Leiomyosarcoma

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Drugs & Therapeutics for Lung Leiomyosarcoma

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Search Clinical Trials , NIH Clinical Center for Lung Leiomyosarcoma

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Genetic Tests for Lung Leiomyosarcoma

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Anatomical Context for Lung Leiomyosarcoma

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The Foundational Model of Anatomy Ontology organs/tissues related to Lung Leiomyosarcoma:

19
The Lung

MalaCards organs/tissues related to Lung Leiomyosarcoma:

41
Lung
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Publications for Lung Leiomyosarcoma

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Articles related to Lung Leiomyosarcoma:

# Title Authors Year
1
Gastrointestinal bleeding in lung leiomyosarcoma history: report of a case. ( 25276388 )
2014
2
Primary lung leiomyosarcoma detected by bronchoscopy cytology. ( 16078256 )
2005
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Variations for Lung Leiomyosarcoma

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Expression for Lung Leiomyosarcoma

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Search GEO for disease gene expression data for Lung Leiomyosarcoma.
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Pathways for Lung Leiomyosarcoma

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Pathways related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
NF-kappaB Signaling 4
11.92 CD34 KIT
2
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.43 CD34 KIT
3
Hematopoietic cell lineage 37
11.31 CD34 KIT
4
Innate Lymphoid Cell Differentiation Pathways 65
11.16 CD34 KIT
5
C-MYB transcription factor network 1
11.05 CD34 KIT
6
Dendritic Cells Developmental Lineage Pathway 65
10.82 CD34 KIT
7
B Cell Development Pathways 65
10.35 CD34 KIT
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GO Terms for Lung Leiomyosarcoma

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Cellular components related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.96 CD34 KIT
2 external side of plasma membrane GO:0009897 8.62 CD34 KIT

Biological processes related to Lung Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 8.96 CD34 KIT
2 hemopoiesis GO:0030097 8.62 CD34 KIT
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Sources for Lung Leiomyosarcoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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