MCID: LNG013
MIFTS: 31

Lung Lymphoma

Categories: Blood diseases, Cancer diseases, Immune diseases, Respiratory diseases

Aliases & Classifications for Lung Lymphoma

MalaCards integrated aliases for Lung Lymphoma:

Name: Lung Lymphoma 12 15
Pulmonary Lymphoma 12 70
Primary Lung Lymphoma 70
Lymphoma of Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6760
UMLS 70 C0519063 C1704383

Summaries for Lung Lymphoma

MalaCards based summary : Lung Lymphoma, also known as pulmonary lymphoma, is related to intravascular large b-cell lymphoma and lymphoproliferative syndrome. An important gene associated with Lung Lymphoma is MALT1 (MALT1 Paracaspase), and among its related pathways/superpathways are B cell receptor signaling pathway (KEGG) and NF-kappaB Signaling. The drugs Radiopharmaceuticals and Fluoroazomycin arabinoside have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and colon, and related phenotypes are hematopoietic system and immune system

Related Diseases for Lung Lymphoma

Diseases related to Lung Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 intravascular large b-cell lymphoma 29.7 MME CD5 BCL6
2 lymphoproliferative syndrome 29.7 TNFRSF8 CD5 BCL6
3 lymphosarcoma 29.7 TNFRSF8 BCL6
4 lymphoma, hodgkin, classic 29.5 TNFRSF8 PAX5 BCL6
5 follicular lymphoma 29.5 MME CD5 BCL6
6 primary central nervous system lymphoma 29.3 PAX5 BCL6
7 sezary's disease 29.3 TNFRSF8 CD5 BCL6
8 nodal marginal zone lymphoma 29.3 SPN MME CD5 BCL6
9 angioimmunoblastic t-cell lymphoma 29.2 TNFRSF8 MME BCL6
10 central nervous system lymphoma 29.1 PAX5 MALT1 BCL6
11 lymphoma 29.0 TNFRSF8 PAX5 MALT1 CD5 BCL6
12 peripheral t-cell lymphoma 29.0 TNFRSF8 MME CD5 BCL6
13 reticulosarcoma 29.0 TNFRSF8 PAX5 BCL6
14 immune deficiency disease 28.7 TNFRSF8 SPN CD79A CD5 BCL6
15 pleural empyema 28.7 TNFRSF8 PAX5 CD79A BCL6
16 burkitt lymphoma 28.6 TNFRSF8 PAX5 MME BCL6
17 lymphoplasmacytic lymphoma 28.4 PAX5 MME CD79A CD5 BCL6
18 leukemia, acute lymphoblastic 28.3 TNFRSF8 PAX5 MME CD5 BCL6
19 b-cell lymphoma 28.1 TNFRSF8 PAX5 MME MALT1 CD5 BCL6
20 cll/sll 28.1 SPN PAX5 MME CD79A CD5 BCL6
21 lymphoma, non-hodgkin, familial 27.8 TNFRSF8 SPN PAX5 MME MALT1 CD79A
22 leukemia, chronic lymphocytic 27.6 TNFRSF8 SPN PAX5 MME CD79A CD5
23 lymphoma, mucosa-associated lymphoid type 27.6 TNFRSF8 SPN PAX5 MME MALT1 CD79A
24 marginal zone b-cell lymphoma 27.3 TNFRSF8 SPN PAX5 MME MALT1 CD79A
25 diffuse large b-cell lymphoma 27.3 TNFRSF8 SPN PAX5 MME MALT1 CD79A
26 thyrotoxic exophthalmos 10.1 MME CD5
27 endocrine exophthalmos 10.1 MME CD5
28 hilar lung carcinoma 10.1 MME CD79A
29 lung hilum cancer 10.1 MME CD79A
30 nodal marginal zone b-cell lymphoma 10.1 MALT1 BCL6
31 liver lymphoma 10.1 MME CD79A
32 parapsoriasis 10.1 TNFRSF8 CD5
33 eye lymphoma 10.1 CD5 BCL6
34 actinobacillosis 10.1 CD79A CD5
35 follicular mucinosis 10.1 TNFRSF8 CD5
36 chest wall lymphoma 10.1 MME BCL6
37 retroperitoneal lymphoma 10.1 TNFRSF8 MME
38 heart lymphoma 10.1 MME BCL6
39 ovarian lymphoma 10.1 MME BCL6
40 orbital cellulitis 10.0 TNFRSF8 MME
41 acute orbital inflammation 10.0 TNFRSF8 MME
42 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.0 TNFRSF8 BCL6
43 central epithelioid sarcoma 10.0 TNFRSF8 MME
44 lymphomatoid granulomatosis 10.0
45 t-cell adult acute lymphocytic leukemia 10.0 TNFRSF8 CD5
46 vulvar proximal-type epithelioid sarcoma 10.0 TNFRSF8 MME
47 orofaciodigital syndrome viii 10.0 MALT1 BCL6
48 hodgkin's lymphoma, mixed cellularity 10.0 TNFRSF8 SPN
49 plasma protein metabolism disease 10.0 MME CD5
50 pilar sheath acanthoma 10.0 TNFRSF8 MME

Graphical network of the top 20 diseases related to Lung Lymphoma:



Diseases related to Lung Lymphoma

Symptoms & Phenotypes for Lung Lymphoma

MGI Mouse Phenotypes related to Lung Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 BCL6 CD5 CD79A MALT1 PAX5 SPN
2 immune system MP:0005387 9.23 BCL6 CD5 CD79A MALT1 MME PAX5

Drugs & Therapeutics for Lung Lymphoma

Drugs for Lung Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Radiopharmaceuticals Phase 1, Phase 2
2 Fluoroazomycin arabinoside Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I/II Imaging Study of 1-a-D-(5-deoxy-5-[18]F-fluoroarabinofuranosyl)-2-nitroimidazole ([18]F-FAZA) in Patients With Known Squamous Cell Carcinoma of the Head & Neck, Small Cell and Non-Small Cell Carcinoma of the Lung, Lymphoma, Glioblastoma Multiforme, Neuroendocrine Tumours or Renal Cell Carcinoma Terminated NCT00323076 Phase 1, Phase 2 18F-FAZA PET Imaging
2 A Multi-Centre, Randomized Controlled Trial of Self-Management and Activation to Reduce Treatment-Related Toxicities in Patients Receiving Adjuvant or First-Line Metastatic Oral or Systematic Therapy for Colorectal, Lymphoma or Lung Cancer (SMARTCare) Active, not recruiting NCT03849950

Search NIH Clinical Center for Lung Lymphoma

Genetic Tests for Lung Lymphoma

Anatomical Context for Lung Lymphoma

MalaCards organs/tissues related to Lung Lymphoma:

40
Lung, Skin, Colon, Pancreas, Thyroid, Prostate, Pituitary

Publications for Lung Lymphoma

Articles related to Lung Lymphoma:

(show top 50) (show all 344)
# Title Authors PMID Year
1
Pulmonary mucosa-associated lymphoid tissue lymphoma: CT findings and pathological basis. 61
33523526 2021
2
Enhancing the differentiation of pulmonary lymphoma and fungal pneumonia in hematological patients using texture analysis in 3-T MRI. 61
32822054 2021
3
The characteristic computed tomography findings of pulmonary B-cell non-Hodgkin's lymphoma and their role in predicting patient survival. 61
33532276 2021
4
Clinicopathological characteristics and prognostic factors of primary pulmonary lymphoma. 61
33717584 2021
5
A Rare Case of Benign Hamartoma and Malignant Primary Pulmonary Lymphoma Coexisting in a Patient Mimicking Invasive Pulmonary Mycosis: a Case Report and Literature Review. 61
33616322 2021
6
Primary pulmonary lymphoma presenting as nodules and masses: a case report and literature review. 61
33478202 2021
7
Treatment and prognosis of primary pulmonary lymphoma: A long-term follow-up study. 61
32779796 2021
8
[Experience with Secondary Pulmonary Lymphoma Diagnosed by Surgical Biopsy]. 61
33271573 2020
9
Proximity to Oil Refineries and Risk of Cancer: A Population-Based Analysis. 61
33269338 2020
10
Primary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation: A case report. 61
33327289 2020
11
Mucosa-associated lymphoid tissue lymphoma with isolated endobronchial involvement. 61
33088571 2020
12
Mimickers of pulmonary lymphoma. 61
32586652 2020
13
T-cell and NK-cell lymphomas in the lung. 61
32448591 2020
14
Primary pulmonary Hodgkin's lymphoma with pulmonary histoplasmosis. 61
33162658 2020
15
Effect of Sustained Smoking Cessation Counseling and Provision of Medication vs Shorter-term Counseling and Medication Advice on Smoking Abstinence in Patients Recently Diagnosed With Cancer: A Randomized Clinical Trial. 61
33048154 2020
16
Abatacept in rheumatoid arthritis and the risk of cancer: a world observational post-marketing study. 61
31880308 2020
17
Synchronous primary pulmonary adenocarcinoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: A case report and literature review. 61
32702827 2020
18
Amyloid nodule and primary pulmonary lymphoma in the same lung: Radiologic-pathologic correlation of a rare combination. 61
32419890 2020
19
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. 61
33506766 2020
20
Mesenteric lymphadenopathy is a key to diagnosis of radiologically challenging pulmonary lymphoma. 61
32351041 2020
21
Ibrutinib resistance in a patient with transformed diffuse large B-cell lymphoma from primary pulmonary mucosa-associated lymphoid tissue lymphoma. 61
31931656 2020
22
Comparison of radiologic characteristics and pathological presentations of primary pulmonary lymphoma in 22 patients. 61
31880183 2020
23
Diagnostic Performance and Reliability of Non-Enhanced Imaging Characterization Quotients for the Differentiation of Infectious and Malignant Pulmonary Nodules in Hematological Patients Using 3T MRI. 61
31648350 2020
24
Clinical, morphological features and prognostic factors associated with interstitial lung disease in primary SjÓ§gren's syndrome: A systematic review from the Italian Society of Rheumatology. 61
31843713 2020
25
Diffuse Large B-Cell Lymphoma Arising from the Lesion of Chronic Lobar Atelectasis. 61
32115495 2020
26
Primary Pulmonary Diffuse Large B Cell Lymphoma Mimicking Metastasis: A Case Report and Literature Review. 61
32606794 2020
27
Primary pulmonary lymphoma manifesting as diffuse ground glass opacities: a case report and literature review. 61
32922618 2020
28
Simultaneous occurrence of invasive pulmonary aspergillosis and diffuse large B-cell lymphoma: case report and literature review. 61
31906982 2020
29
Asymptomatic patient with "lumpy and bumpy" airways. A case of pulmonary MALToma. 61
33393656 2020
30
Simultaneous bilateral spontaneous pneumothorax as the first manifestation of primary pulmonary MALT lymphoma. 61
33062114 2020
31
Primary lung intravascular large B-Cell lymphoma clinically mimicking sarcoidosis: A rare case report and review of literature. 61
31921597 2020
32
F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Images of Severe Primary Lung Lymphoma. 61
31949381 2020
33
Primary pulmonary lymphoma: imaging findings in 30 cases. 61
31583557 2019
34
Prognostic factors and nomogram for survival prediction in patients with primary pulmonary lymphoma: a SEER population-based study. 61
31322026 2019
35
A Case of Lung Involvement in Peripheral T Cell Lymphoma. 61
31625353 2019
36
Pulmonary mucosa-associated lymphoid tissue lymphoma mimicking lung cancer. 61
31428404 2019
37
Alveolar Sarcoidosis With Intense FDG Uptake, Mimicking Multi-focal Pneumonia and Infiltrative Lung Malignancy. 61
31274614 2019
38
Impact of Oncology Drug Shortages on Chemotherapy Treatment. 61
30739322 2019
39
Dilated Air Bronchogram Inside Areas of Consolidation: A Tomographic Finding Suggestive of Pulmonary Lymphoma. 61
30606629 2019
40
Pulmonary MALT Lymphoma has variable features on CT. 61
31209274 2019
41
Clinical features and outcomes of pulmonary lymphoma: A single center experience of 180 cases. 61
31097092 2019
42
Diagnostic and Therapeutic Implications of Pulmonary Lymphoma Associated With Nodular Amyloidosis. 61
30395852 2019
43
Primary Pulmonary Lymphoma: A Retrospective Analysis of 27 Cases in a Single Tertiary Hospital. 61
30904047 2019
44
Abatacept initiation in rheumatoid arthritis and the risk of cancer: a population-based comparative cohort study. 61
30535094 2019
45
Primary pulmonary lymphoma in children. 61
30736822 2019
46
A Rare Case of Primary Pulmonary Anaplastic Large Cell Lymphoma. 61
31583219 2019
47
Rare Primary Pulmonary Marginal Zone Lymphoma Presenting with Incidental Pulmonary Nodules. 61
31016061 2019
48
Multiple cystic lung lesions and autoimmune thrombocytopaenia developing after chemotherapy for pulmonary indolent B-cell lymphoma with plasmacytic differentiation. 61
30567252 2018
49
Contrast-Enhanced Ultrasound in Pulmonary Lymphoma: A Small Pilot Study. 61
29732588 2018
50
Diffuse large B cell lymphoma with superimposed lung abscess: potential role for intracavitary fibrinolytic therapy through a percutaneous drain to facilitate lung abscess drainage. 61
30567091 2018

Variations for Lung Lymphoma

Expression for Lung Lymphoma

Search GEO for disease gene expression data for Lung Lymphoma.

Pathways for Lung Lymphoma

GO Terms for Lung Lymphoma

Cellular components related to Lung Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 SPN CD79A CD5

Biological processes related to Lung Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell activation GO:0042113 8.62 MALT1 CD79A

Molecular functions related to Lung Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.8 TNFRSF8 SPN CD79A

Sources for Lung Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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