MCID: LNG091
MIFTS: 24

Lung Mucoepidermoid Carcinoma

Categories: Cancer diseases, Respiratory diseases, Oral diseases, Gastrointestinal diseases

Aliases & Classifications for Lung Mucoepidermoid Carcinoma

MalaCards integrated aliases for Lung Mucoepidermoid Carcinoma:

Name: Lung Mucoepidermoid Carcinoma 12 15
Mucoepidermoid Carcinoma of Lung 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0050932
UMLS 73 C1708778

Summaries for Lung Mucoepidermoid Carcinoma

Disease Ontology : 12 A lung carcinoma that has_material_basis in a combination of squamous cells, mucus secreting cells and intermediate cells.

MalaCards based summary : Lung Mucoepidermoid Carcinoma, also known as mucoepidermoid carcinoma of lung, is related to mucoepidermoid carcinoma and adenocarcinoma, and has symptoms including hemoptysis and wheezing. An important gene associated with Lung Mucoepidermoid Carcinoma is PTPN14 (Protein Tyrosine Phosphatase, Non-Receptor Type 14), and among its related pathways/superpathways are Development Slit-Robo signaling and Guidance Cues and Growth Cone Motility. Affiliated tissues include lung and brain.

Related Diseases for Lung Mucoepidermoid Carcinoma

Diseases related to Lung Mucoepidermoid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mucoepidermoid carcinoma 10.2
2 adenocarcinoma 9.8
3 tubulin, beta 9.7 TUBB TUBB2A
4 charcot-marie-tooth disease, axonal, type 2k 9.4 TUBB TUBB2A

Symptoms & Phenotypes for Lung Mucoepidermoid Carcinoma

UMLS symptoms related to Lung Mucoepidermoid Carcinoma:


hemoptysis, wheezing

Drugs & Therapeutics for Lung Mucoepidermoid Carcinoma

Search Clinical Trials , NIH Clinical Center for Lung Mucoepidermoid Carcinoma

Genetic Tests for Lung Mucoepidermoid Carcinoma

Anatomical Context for Lung Mucoepidermoid Carcinoma

MalaCards organs/tissues related to Lung Mucoepidermoid Carcinoma:

41
Lung, Brain

Publications for Lung Mucoepidermoid Carcinoma

Articles related to Lung Mucoepidermoid Carcinoma:

# Title Authors Year
1
Primary lung mucoepidermoid carcinoma: Analysis of prognostic factors using Surveillance, Epidemiology, and End Results Program (SEER). ( 26663856 )
2015
2
Brain metastasis from a lung mucoepidermoid carcinoma mimicking a brain abscess. ( 26167374 )
2015
3
Mixed lung mucoepidermoid carcinoma and adenocarcinoma with identical mutations in an epidermal growth factor receptor gene. ( 25087791 )
2014
4
t(11;19)(q21;p12~p13.11) and MECT1-MAML2 fusion transcript expression as a prognostic marker in infantile lung mucoepidermoid carcinoma. ( 17618868 )
2007
5
Effects of lovastatin on the fatty acid desaturation in a human lung mucoepidermoid carcinoma grown in nude mice. ( 9132162 )
1996

Variations for Lung Mucoepidermoid Carcinoma

Cosmic variations for Lung Mucoepidermoid Carcinoma:

9
(show top 50) (show all 549)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6213 EGFR lung,NS,carcinoma,mucoepidermoid carcinoma c.2582T>A p.L861Q 7:55191831-55191831 11
2 COSM6966579 ZFHX3 lung,NS,carcinoma,undifferentiated carcinoma c.1172A>G p.Q391R 16:72958974-72958974 8
3 COSM6953383 ZFHX3 lung,NS,carcinoma,undifferentiated carcinoma c.1144G>T p.G382C 16:72959002-72959002 8
4 COSM6980872 YAP1 lung,NS,carcinoma,undifferentiated carcinoma c.1142C>T p.P381L 11:102229729-102229729 8
5 COSM95548 XRCC6 lung,NS,carcinoma,undifferentiated carcinoma c.1159A>C p.I387L 22:41653558-41653558 8
6 COSM95544 XRCC1 lung,NS,carcinoma,undifferentiated carcinoma c.1207A>G p.M403V 19:43546970-43546970 8
7 COSM6980399 WT1 lung,NS,carcinoma,undifferentiated carcinoma c.233G>A p.W78* 11:32434909-32434909 8
8 COSM6938307 WT1 lung,NS,carcinoma,undifferentiated carcinoma c.1156A>T p.K386* 11:32392044-32392044 8
9 COSM95531 WNT8A lung,NS,carcinoma,undifferentiated carcinoma c.368G>C p.G123A 5:138088927-138088927 8
10 COSM95521 WNT10B lung,NS,carcinoma,undifferentiated carcinoma c.1006A>C p.K336Q 12:48966259-48966259 8
11 COSM95485 USP5 lung,NS,carcinoma,undifferentiated carcinoma c.755C>T p.T252I 12:6856877-6856877 8
12 COSM95476 USP38 lung,NS,carcinoma,undifferentiated carcinoma c.994G>C p.A332P 4:143197868-143197868 8
13 COSM96265 USP32 lung,NS,carcinoma,undifferentiated carcinoma c.192T>A p.I64I 17:60301699-60301699 8
14 COSM94159 UBR5 lung,NS,carcinoma,undifferentiated carcinoma c.1555A>G p.S519G 8:102326590-102326590 8
15 COSM94158 UBR5 lung,NS,carcinoma,undifferentiated carcinoma c.2691A>T p.Q897H 8:102305221-102305221 8
16 COSM6983597 U2AF1 lung,NS,carcinoma,undifferentiated carcinoma c.319G>C p.D107H 21:43095467-43095467 8
17 COSM95420 TYK2 lung,NS,carcinoma,undifferentiated carcinoma c.3560G>T p.C1187F 19:10350838-10350838 8
18 COSM6942934 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.1922C>T p.S641L 14:81143980-81143980 8
19 COSM6953382 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.937A>C p.K313Q 14:81142995-81142995 8
20 COSM6966576 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.412C>T p.L138F 14:81091088-81091088 8
21 COSM6980873 TSC2 lung,NS,carcinoma,undifferentiated carcinoma c.1840G>T p.A614S 16:2071510-2071510 8
22 COSM6980394 TSC1 lung,NS,carcinoma,undifferentiated carcinoma c.694G>T p.E232* 9:132921406-132921406 8
23 COSM6980408 TRAF7 lung,NS,carcinoma,undifferentiated carcinoma c.1193C>T p.P398L 16:2173978-2173978 8
24 COSM6940747 TRAF7 lung,NS,carcinoma,undifferentiated carcinoma c.1287C>G p.Y429* 16:2174274-2174274 8
25 COSM95390 TRAF5 lung,NS,carcinoma,undifferentiated carcinoma c.302G>C p.R101T 1:211356392-211356392 8
26 COSM22908 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.376-1G>T p.? 17:7675237-7675237 8
27 COSM11232 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.842A>G p.D281G 17:7673778-7673778 8
28 COSM45304 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.375+1G>A p.? 17:7675993-7675993 8
29 COSM10768 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.535C>T p.H179Y 17:7675077-7675077 8
30 COSM10742 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.578A>G p.H193R 17:7674953-7674953 8
31 COSM11333 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.499C>T p.Q167* 17:7675113-7675113 8
32 COSM10779 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.818G>T p.R273L 17:7673802-7673802 8
33 COSM11354 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.991C>T p.Q331* 17:7673537-7673537 8
34 COSM11073 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.1024C>T p.R342* 17:7670685-7670685 8
35 COSM6815 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.461G>T p.G154V 17:7675151-7675151 8
36 COSM43750 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.811G>T p.E271* 17:7673809-7673809 8
37 COSM6913 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.783-1G>T p.? 17:7673838-7673838 8
38 COSM10645 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.527G>T p.C176F 17:7675085-7675085 8
39 COSM44295 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.993+1G>A p.? 17:7673534-7673534 8
40 COSM13584 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.919+1G>T p.? 17:7673700-7673700 8
41 COSM10660 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 8
42 COSM43753 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.560-1G>A p.? 17:7674972-7674972 8
43 COSM44240 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.514G>T p.V172F 17:7675098-7675098 8
44 COSM44891 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.796G>T p.G266* 17:7673824-7673824 8
45 COSM10889 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.536A>G p.H179R 17:7675076-7675076 8
46 COSM10714 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.473G>T p.R158L 17:7675139-7675139 8
47 COSM95367 TLR5 lung,NS,carcinoma,undifferentiated carcinoma c.1A>G p.M1V 1:223113031-223113031 8
48 COSM95359 TLR4 lung,NS,carcinoma,undifferentiated carcinoma c.337C>A p.P113T 9:117712465-117712465 8
49 COSM95356 TLR2 lung,NS,carcinoma,undifferentiated carcinoma c.1169A>G p.Q390R 4:153704076-153704076 8
50 COSM95347 TLN1 lung,NS,carcinoma,undifferentiated carcinoma c.1087C>T p.P363S 9:35721665-35721665 8

Expression for Lung Mucoepidermoid Carcinoma

Search GEO for disease gene expression data for Lung Mucoepidermoid Carcinoma.

Pathways for Lung Mucoepidermoid Carcinoma

GO Terms for Lung Mucoepidermoid Carcinoma

Cellular components related to Lung Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell body GO:0044297 8.62 EPHA4 TUBB

Biological processes related to Lung Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microtubule cytoskeleton organization GO:0000226 9.16 TUBB TUBB2A
2 microtubule-based process GO:0007017 8.96 TUBB TUBB2A
3 cytoskeleton organization GO:0007010 8.8 PAK6 TUBB TUBB2A

Molecular functions related to Lung Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 TUBB TUBB2A

Sources for Lung Mucoepidermoid Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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