MCID: LNG020
MIFTS: 38

Lung Oat Cell Carcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Lung Oat Cell Carcinoma

MalaCards integrated aliases for Lung Oat Cell Carcinoma:

Name: Lung Oat Cell Carcinoma 12 15
Oat Cell Carcinoma 12
Carcinoma Oat Cell 55

Classifications:



External Ids:

Disease Ontology 12 DOID:5411
SNOMED-CT 68 76817009
UMLS 73 C0262584

Summaries for Lung Oat Cell Carcinoma

MalaCards based summary : Lung Oat Cell Carcinoma, also known as oat cell carcinoma, is related to gallbladder small cell carcinoma and small cell cancer of the lung. An important gene associated with Lung Oat Cell Carcinoma is AVP (Arginine Vasopressin), and among its related pathways/superpathways are Neuroscience and G alpha (s) signalling events. Affiliated tissues include lung, liver and pancreas, and related phenotype is renal/urinary system.

Related Diseases for Lung Oat Cell Carcinoma

Diseases related to Lung Oat Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 gallbladder small cell carcinoma 32.0 CHGA ENO2
2 small cell cancer of the lung 31.3 AVP CALCA CHGA ENO2 POMC
3 inappropriate adh syndrome 30.4 AVP POMC
4 carcinoid syndrome 30.2 CALCA CHGA ENO2
5 diabetes insipidus 30.1 AVP POMC
6 merkel cell carcinoma 29.9 CHGA ENO2
7 islet cell tumor 29.9 CALCA CHGA
8 parathyroid adenoma 29.8 CALCA CHGA
9 small cell carcinoma 29.7 CALCA CHGA ENO2
10 somatostatinoma 29.7 CALCA CHGA ENO2
11 esophagus small cell carcinoma 11.6
12 prostate small cell carcinoma 11.2
13 central nervous system germinoma 10.2 AVP POMC
14 tuberculous epididymitis 10.2 AVP POMC
15 central nervous system germ cell tumor 10.2 AVP POMC
16 conn's syndrome 10.2
17 lactic acidosis 10.2
18 diabetes insipidus, neurohypophyseal 10.2 AVP POMC
19 malignant teratoma 10.2 AVP ENO2
20 lymphocytic hypophysitis 10.1 ENO2 POMC
21 premenstrual tension 10.1 AVP POMC
22 chromophobe adenoma 10.1 AVP POMC
23 pituitary hormone deficiency, combined, 2 10.1 AVP POMC
24 tracheal cancer 10.1 AVP ENO2
25 pituitary carcinoma 10.1 CHGA POMC
26 urinary bladder small cell neuroendocrine carcinoma 10.1 CHGA ENO2
27 intracranial primitive neuroectodermal tumor 10.1 CHGA ENO2
28 pituitary gland disease 10.1 AVP POMC
29 auditory system cancer 10.1 CHGA ENO2
30 small cell carcinoma of the bladder 10.1 CHGA ENO2
31 epithelioid malignant peripheral nerve sheath tumor 10.1 CHGA ENO2
32 pulmonary large cell neuroendocrine carcinoma 10.1 CHGA ENO2
33 adrenal rest tumor 10.1 ENO2 POMC
34 large cell neuroendocrine carcinoma 10.1 CHGA ENO2
35 goblet cell carcinoid 10.1 CHGA ENO2
36 pancreas disease 10.1 AVP POMC
37 cauda equina neoplasm 10.1 CHGA ENO2
38 autonomic nervous system benign neoplasm 10.1 CHGA ENO2
39 nodular ganglioneuroblastoma 10.1 CHGA ENO2
40 pineocytoma 10.1 CHGA ENO2
41 gastric small cell carcinoma 10.1 CHGA ENO2
42 subependymoma 10.1 CHGA ENO2
43 carcinoid tumors, intestinal 10.1 CHGA ENO2
44 respiratory system benign neoplasm 10.1 CHGA ENO2
45 gastric squamous cell carcinoma 10.1 CHGA ENO2
46 papillary ependymoma 10.1 CHGA ENO2
47 duodenal gastrinoma 10.1 CHGA ENO2
48 central neurocytoma 10.1 CHGA ENO2
49 spinal meningioma 10.1 CHGA ENO2
50 spinal canal and spinal cord meningioma 10.1 CHGA ENO2

Graphical network of the top 20 diseases related to Lung Oat Cell Carcinoma:



Diseases related to Lung Oat Cell Carcinoma

Symptoms & Phenotypes for Lung Oat Cell Carcinoma

MGI Mouse Phenotypes related to Lung Oat Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 AVP CHGA OAT POMC

Drugs & Therapeutics for Lung Oat Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Lung Oat Cell Carcinoma

Genetic Tests for Lung Oat Cell Carcinoma

Anatomical Context for Lung Oat Cell Carcinoma

MalaCards organs/tissues related to Lung Oat Cell Carcinoma:

41
Lung, Liver, Pancreas, Pituitary, Trachea, Kidney, Breast

Publications for Lung Oat Cell Carcinoma

Articles related to Lung Oat Cell Carcinoma:

(show top 50) (show all 282)
# Title Authors Year
1
Oat-cell carcinoma of the tongue. ( 26956201 )
2016
2
A note from history: the saga of carcinoid and oat-cell carcinoma. ( 18988939 )
2008
3
F-18 FDG PET imaging of urinary bladder oat cell carcinoma with widespread osseous metastases. ( 16855436 )
2006
4
(18)FDG PET in primary oat cell carcinoma of the esophagus. ( 15805695 )
2005
5
Extra-pulmonary oat cell carcinoma: report of two cases. ( 16022138 )
2005
6
Oat cell carcinoma of the oesophagus--a case report and review of literature. ( 16498759 )
2005
7
Progressive encephalomyelitis with rigidity: a paraneoplastic presentation of oat cell carcinoma of the lung. Case report. ( 15273862 )
2004
8
Primary oat cell carcinoma of the breast: imaging features. ( 15385324 )
2004
9
Case report: esophageal collision tumor (oat cell carcinoma and adenocarcinoma) in Barrett's esophagus: immunohistochemical, electron microscopy and LOH analysis. ( 12507278 )
2003
10
Extrapulmonary oat-cell carcinoma presenting as a primary left ventricular tumor: a case report. ( 12011814 )
2002
11
Oat-cell carcinoma of the prostate. Diagnosis, prognosis and therapeutic implications. ( 11598447 )
2001
12
Primary small cell (oat cell) carcinoma of the breast: report of a case and review of the literature. ( 11107070 )
2000
13
Oat cell carcinoma metastasis to the foot. ( 9470118 )
1998
14
Oat cell carcinoma of the tongue from an unknown primary. ( 9557413 )
1998
15
Cytologic diagnosis of a primary pure oat cell carcinoma of the bladder in voided urine. A case report. ( 9990258 )
1997
16
The radiological appearances of small cell (oat cell) carcinoma of the oesophagus. ( 8580063 )
1995
17
Cutaneous sarcoid granulomas with oat cell carcinoma of the lung. ( 8589487 )
1995
18
Oat-cell carcinoma of the esophagus. ( 7976920 )
1994
19
Oat cell carcinoma of the lung in patients with CLL. ( 8027638 )
1994
20
Oncogenic hypophosphataemia and ectopic corticotrophin secretion due to oat cell carcinoma of the trachea. ( 8132816 )
1994
21
Oat cell carcinoma of the gallbladder. A rare and highly lethal neoplasm. ( 8215821 )
1993
22
Spontaneous 19-year regression of oat cell carcinoma with scalene node metastasis. ( 8242565 )
1993
23
An unusual presentation of oat cell carcinoma. ( 8393909 )
1993
24
Oat-cell carcinoma of primary location in the pericardium. A case report. ( 8394036 )
1993
25
Oat cell carcinoma in the pancreas: an unusual cause of Cushing's syndrome. ( 1316198 )
1992
26
Oat cell carcinoma of urinary bladder. ( 1319621 )
1992
27
Adrenal insufficiency due to bilateral metastases from oat cell carcinoma of the oesophagus. ( 1651742 )
1991
28
Is control of the primary tumour worthwhile in non-oat cell carcinoma of the bronchus? ( 1657111 )
1991
29
Ocular metastasis of pulmonary oat cell carcinoma. ( 1667664 )
1991
30
Unusual malignant neoplasms of the esophagus. Oat cell carcinoma, melanoma, and sarcoma. ( 1702494 )
1991
31
Anaplastic small cell (oat cell) carcinoma of the tonsils: report of two cases. ( 2466759 )
1989
32
Oat cell carcinoma of the larynx. A study of six new cases. ( 2538387 )
1989
33
Placental metastasis from maternal bronchial oat cell carcinoma. ( 2540729 )
1989
34
Upper-half body irradiation for oat cell carcinoma of the bronchus. ( 2544242 )
1989
35
Unresectable non-oat cell carcinoma of the lung: definitive radiation therapy. ( 2549566 )
1989
36
Identification of vasopressin-like peptides in the plasma of a patient with the syndrome of inappropriate secretion of antidiuretic hormone and an oat cell carcinoma. ( 2849277 )
1988
37
Primary and secondary oat cell carcinoma of the esophagus: possible diagnosis during esophagoscopy. ( 2827458 )
1988
38
Oat cell carcinoma of the esophagus with multiple differentiation. ( 2852698 )
1988
39
Primary oat cell carcinoma of the common bile duct. ( 2852719 )
1988
40
Omnipause neurons in two cases of opsoclonus associated with oat cell carcinoma of the lung. ( 2827840 )
1987
41
Leg paralysis in man with oat cell carcinoma. ( 3031094 )
1987
42
Long-term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive radiotherapy. Report by the Radiation Therapy Oncology Group. ( 3032394 )
1987
43
Large fraction irradiation with or without misonidazole in advanced non-oat cell carcinoma of the lung: a phase III randomized trial of the RTOG. Radiation Therapy Oncology Group. ( 3034841 )
1987
44
Oat cell carcinoma of the bronchus and acute pancreatitis. ( 3040475 )
1987
45
Primary oat cell carcinoma of the esophagus. ( 3026169 )
1987
46
Primary oat cell carcinoma of the larynx. ( 3030091 )
1987
47
Extrapulmonary oat-cell carcinoma of the tonsil. ( 3030689 )
1987
48
Long term survival case of small (oat) cell carcinoma of the rectum. ( 3033985 )
1987
49
The use of antikeratin antibodies in the immunohistochemical distinction between neuroendocrine (Merkel cell) carcinoma of the skin, lymphoma, and oat cell carcinoma. ( 2425928 )
1986
50
Oat cell carcinoma of the urinary tract. An immunohistochemical and electron microscopic study. ( 2429758 )
1986

Variations for Lung Oat Cell Carcinoma

Cosmic variations for Lung Oat Cell Carcinoma:

9 (show top 50) (show all 548)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6953383 ZFHX3 lung,NS,carcinoma,undifferentiated carcinoma c.1144G>T p.G382C 16:72959002-72959002 6
2 COSM6966579 ZFHX3 lung,NS,carcinoma,undifferentiated carcinoma c.1172A>G p.Q391R 16:72958974-72958974 6
3 COSM6980872 YAP1 lung,NS,carcinoma,undifferentiated carcinoma c.1142C>T p.P381L 11:102229729-102229729 6
4 COSM95548 XRCC6 lung,NS,carcinoma,undifferentiated carcinoma c.1159A>C p.I387L 22:41653558-41653558 6
5 COSM95544 XRCC1 lung,NS,carcinoma,undifferentiated carcinoma c.1207A>G p.M403V 19:43546970-43546970 6
6 COSM6980399 WT1 lung,NS,carcinoma,undifferentiated carcinoma c.233G>A p.W78* 11:32434909-32434909 6
7 COSM6938307 WT1 lung,NS,carcinoma,undifferentiated carcinoma c.1156A>T p.K386* 11:32392044-32392044 6
8 COSM95531 WNT8A lung,NS,carcinoma,undifferentiated carcinoma c.368G>C p.G123A 5:138088927-138088927 6
9 COSM95521 WNT10B lung,NS,carcinoma,undifferentiated carcinoma c.1006A>C p.K336Q 12:48966259-48966259 6
10 COSM95485 USP5 lung,NS,carcinoma,undifferentiated carcinoma c.755C>T p.T252I 12:6856877-6856877 6
11 COSM95476 USP38 lung,NS,carcinoma,undifferentiated carcinoma c.994G>C p.A332P 4:143197868-143197868 6
12 COSM96265 USP32 lung,NS,carcinoma,undifferentiated carcinoma c.192T>A p.I64I 17:60301699-60301699 6
13 COSM94159 UBR5 lung,NS,carcinoma,undifferentiated carcinoma c.1555A>G p.S519G 8:102326590-102326590 6
14 COSM94158 UBR5 lung,NS,carcinoma,undifferentiated carcinoma c.2691A>T p.Q897H 8:102305221-102305221 6
15 COSM6983597 U2AF1 lung,NS,carcinoma,undifferentiated carcinoma c.319G>C p.D107H 21:43095467-43095467 6
16 COSM95420 TYK2 lung,NS,carcinoma,undifferentiated carcinoma c.3560G>T p.C1187F 19:10350838-10350838 6
17 COSM6942934 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.1922C>T p.S641L 14:81143980-81143980 6
18 COSM6953382 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.937A>C p.K313Q 14:81142995-81142995 6
19 COSM6966576 TSHR lung,NS,carcinoma,undifferentiated carcinoma c.412C>T p.L138F 14:81091088-81091088 6
20 COSM6980873 TSC2 lung,NS,carcinoma,undifferentiated carcinoma c.1840G>T p.A614S 16:2071510-2071510 6
21 COSM6980394 TSC1 lung,NS,carcinoma,undifferentiated carcinoma c.694G>T p.E232* 9:132921406-132921406 6
22 COSM6980408 TRAF7 lung,NS,carcinoma,undifferentiated carcinoma c.1193C>T p.P398L 16:2173978-2173978 6
23 COSM6940747 TRAF7 lung,NS,carcinoma,undifferentiated carcinoma c.1287C>G p.Y429* 16:2174274-2174274 6
24 COSM95390 TRAF5 lung,NS,carcinoma,undifferentiated carcinoma c.302G>C p.R101T 1:211356392-211356392 6
25 COSM11232 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.842A>G p.D281G 17:7673778-7673778 6
26 COSM45304 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.375+1G>A p.? 17:7675993-7675993 6
27 COSM10768 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.535C>T p.H179Y 17:7675077-7675077 6
28 COSM10742 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.578A>G p.H193R 17:7674953-7674953 6
29 COSM11333 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.499C>T p.Q167* 17:7675113-7675113 6
30 COSM10779 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.818G>T p.R273L 17:7673802-7673802 6
31 COSM11354 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.991C>T p.Q331* 17:7673537-7673537 6
32 COSM11073 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.1024C>T p.R342* 17:7670685-7670685 6
33 COSM6815 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.461G>T p.G154V 17:7675151-7675151 6
34 COSM43750 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.811G>T p.E271* 17:7673809-7673809 6
35 COSM6913 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.783-1G>T p.? 17:7673838-7673838 6
36 COSM10645 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.527G>T p.C176F 17:7675085-7675085 6
37 COSM44295 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.993+1G>A p.? 17:7673534-7673534 6
38 COSM13584 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.919+1G>T p.? 17:7673700-7673700 6
39 COSM10660 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 6
40 COSM43753 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.560-1G>A p.? 17:7674972-7674972 6
41 COSM44240 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.514G>T p.V172F 17:7675098-7675098 6
42 COSM44891 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.796G>T p.G266* 17:7673824-7673824 6
43 COSM10889 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.536A>G p.H179R 17:7675076-7675076 6
44 COSM10714 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.473G>T p.R158L 17:7675139-7675139 6
45 COSM22908 TP53 lung,NS,carcinoma,undifferentiated carcinoma c.376-1G>T p.? 17:7675237-7675237 6
46 COSM95367 TLR5 lung,NS,carcinoma,undifferentiated carcinoma c.1A>G p.M1V 1:223113031-223113031 6
47 COSM95359 TLR4 lung,NS,carcinoma,undifferentiated carcinoma c.337C>A p.P113T 9:117712465-117712465 6
48 COSM95356 TLR2 lung,NS,carcinoma,undifferentiated carcinoma c.1169A>G p.Q390R 4:153704076-153704076 6
49 COSM95347 TLN1 lung,NS,carcinoma,undifferentiated carcinoma c.1087C>T p.P363S 9:35721665-35721665 6
50 COSM95342 TLN1 lung,NS,carcinoma,undifferentiated carcinoma c.5624C>T p.S1875L 9:35705660-35705660 6

Expression for Lung Oat Cell Carcinoma

Search GEO for disease gene expression data for Lung Oat Cell Carcinoma.

Pathways for Lung Oat Cell Carcinoma

Pathways related to Lung Oat Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 AVP CALCA ENO2 POMC
2 11.3 AVP CALCA POMC

GO Terms for Lung Oat Cell Carcinoma

Cellular components related to Lung Oat Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 AVP CALCA CHGA ENO2 POMC
2 secretory granule GO:0030141 8.8 AVP CHGA POMC

Biological processes related to Lung Oat Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.43 AVP CALCA POMC
2 positive regulation of cell growth GO:0030307 9.32 AVP INO80
3 generation of precursor metabolites and energy GO:0006091 9.16 AVP POMC
4 cell-cell signaling GO:0007267 9.13 AVP CALCA POMC
5 regulation of blood pressure GO:0008217 8.8 CALCA CHGA POMC

Molecular functions related to Lung Oat Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.13 AVP CALCA POMC
2 hormone activity GO:0005179 8.8 AVP CALCA POMC

Sources for Lung Oat Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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