MCID: LNG016
MIFTS: 31

Lung Papillary Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Lung Papillary Adenocarcinoma

MalaCards integrated aliases for Lung Papillary Adenocarcinoma:

Name: Lung Papillary Adenocarcinoma 12 15
Papillary Lung Adenocarcinoma 17 74
Papillary Adenocarcinoma of the Lung 12

Classifications:



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Disease Ontology 12 DOID:5588
NCIt 51 C5650
UMLS 74 C1335325

Summaries for Lung Papillary Adenocarcinoma

Disease Ontology : 12 A papillary adenocarcinoma that is located in the lung.

MalaCards based summary : Lung Papillary Adenocarcinoma, also known as papillary lung adenocarcinoma, is related to lung cancer susceptibility 3 and papillary adenocarcinoma, and has symptoms including fever, dyspnea and hemoptysis. An important gene associated with Lung Papillary Adenocarcinoma is RRM1 (Ribonucleotide Reductase Catalytic Subunit M1), and among its related pathways/superpathways are Gastric cancer and Glioma. Affiliated tissues include lung and the lung, and related phenotypes are integument and neoplasm

Related Diseases for Lung Papillary Adenocarcinoma

Graphical network of the top 20 diseases related to Lung Papillary Adenocarcinoma:



Diseases related to Lung Papillary Adenocarcinoma

Symptoms & Phenotypes for Lung Papillary Adenocarcinoma

UMLS symptoms related to Lung Papillary Adenocarcinoma:


fever, dyspnea, hemoptysis, coughing

MGI Mouse Phenotypes related to Lung Papillary Adenocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.35 ALK ERCC1 KEAP1 NFE2L2 TP53
2 neoplasm MP:0002006 8.92 ALK ERCC1 NFE2L2 TP53

Drugs & Therapeutics for Lung Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Lung Papillary Adenocarcinoma

Genetic Tests for Lung Papillary Adenocarcinoma

Anatomical Context for Lung Papillary Adenocarcinoma

MalaCards organs/tissues related to Lung Papillary Adenocarcinoma:

42
Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Lung Papillary Adenocarcinoma:

20
The Lung

Publications for Lung Papillary Adenocarcinoma

Articles related to Lung Papillary Adenocarcinoma:

# Title Authors Year
1
Papillary lung adenocarcinoma with psammomatous calcifications. ( 30094154 )
2018
2
c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. ( 27602772 )
2016
3
Lung papillary adenocarcinoma complicated with paraneoplastic autoimmune hemolytic anemia: A case report. ( 26766978 )
2014

Variations for Lung Papillary Adenocarcinoma

Expression for Lung Papillary Adenocarcinoma

Search GEO for disease gene expression data for Lung Papillary Adenocarcinoma.

Pathways for Lung Papillary Adenocarcinoma

GO Terms for Lung Papillary Adenocarcinoma

Cellular components related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.17 EML4 ERCC1 KEAP1 NFE2L2 RRM1 TP53
2 transcription factor TFIID complex GO:0005669 8.96 ERCC1 TP53

Biological processes related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.5 ALK ERCC1 TP53
2 cellular response to drug GO:0035690 9.37 NFE2L2 TP53
3 nucleotide-excision repair GO:0006289 9.26 ERCC1 TP53
4 cellular response to glucose starvation GO:0042149 9.16 NFE2L2 TP53
5 positive regulation of reactive oxygen species metabolic process GO:2000379 8.96 NFE2L2 TP53
6 proteasomal ubiquitin-independent protein catabolic process GO:0010499 8.62 KEAP1 NFE2L2

Molecular functions related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.56 ALK KEAP1 RRM1 TP53
2 transcription factor binding GO:0008134 9.33 KEAP1 NFE2L2 TP53
3 TFIID-class transcription factor complex binding GO:0001094 8.96 ERCC1 TP53
4 disordered domain specific binding GO:0097718 8.8 KEAP1 RRM1 TP53

Sources for Lung Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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