MCID: LNG016
MIFTS: 28

Lung Papillary Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Lung Papillary Adenocarcinoma

MalaCards integrated aliases for Lung Papillary Adenocarcinoma:

Name: Lung Papillary Adenocarcinoma 12 15
Papillary Adenocarcinoma of the Lung 12
Papillary Lung Adenocarcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5588
NCIt 50 C5650
UMLS 73 C1335325

Summaries for Lung Papillary Adenocarcinoma

MalaCards based summary : Lung Papillary Adenocarcinoma, also known as papillary adenocarcinoma of the lung, is related to bladder squamous cell carcinoma and primary peritoneal carcinoma, and has symptoms including coughing, dyspnea and fever. An important gene associated with Lung Papillary Adenocarcinoma is RRM1 (Ribonucleotide Reductase Catalytic Subunit M1), and among its related pathways/superpathways are DNA Damage and Pathways in cancer. Affiliated tissues include lung, and related phenotypes are integument and neoplasm

Related Diseases for Lung Papillary Adenocarcinoma

Graphical network of the top 20 diseases related to Lung Papillary Adenocarcinoma:



Diseases related to Lung Papillary Adenocarcinoma

Symptoms & Phenotypes for Lung Papillary Adenocarcinoma

UMLS symptoms related to Lung Papillary Adenocarcinoma:


coughing, dyspnea, fever, hemoptysis

MGI Mouse Phenotypes related to Lung Papillary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.35 ALK ERCC1 KEAP1 NFE2L2 TP53
2 neoplasm MP:0002006 8.92 ALK ERCC1 NFE2L2 TP53

Drugs & Therapeutics for Lung Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Lung Papillary Adenocarcinoma

Genetic Tests for Lung Papillary Adenocarcinoma

Anatomical Context for Lung Papillary Adenocarcinoma

MalaCards organs/tissues related to Lung Papillary Adenocarcinoma:

41
Lung

Publications for Lung Papillary Adenocarcinoma

Articles related to Lung Papillary Adenocarcinoma:

# Title Authors Year
1
Lung papillary adenocarcinoma complicated with paraneoplastic autoimmune hemolytic anemia: A case report. ( 26766978 )
2014

Variations for Lung Papillary Adenocarcinoma

Expression for Lung Papillary Adenocarcinoma

Search GEO for disease gene expression data for Lung Papillary Adenocarcinoma.

Pathways for Lung Papillary Adenocarcinoma

Pathways related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 ERCC1 RRM1 TP53
2 11.74 ALK EML4 KEAP1 NFE2L2 TP53
3 11.27 ERCC1 TP53
4 11.27 KEAP1 NFE2L2 TP53
5 11.08 NFE2L2 TP53
6 10.64 KEAP1 NFE2L2
7 10.33 KEAP1 NFE2L2

GO Terms for Lung Papillary Adenocarcinoma

Cellular components related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.23 ALK EML4 ERCC1 KEAP1 NFE2L2 RRM1
2 transcription factor TFIID complex GO:0005669 8.96 ERCC1 TP53

Biological processes related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.54 ALK ERCC1 TP53
2 cellular response to drug GO:0035690 9.4 NFE2L2 TP53
3 nucleotide-excision repair GO:0006289 9.32 ERCC1 TP53
4 cellular response to glucose starvation GO:0042149 9.26 NFE2L2 TP53
5 positive regulation of reactive oxygen species metabolic process GO:2000379 9.16 NFE2L2 TP53
6 proteasomal ubiquitin-independent protein catabolic process GO:0010499 8.96 KEAP1 NFE2L2
7 response to X-ray GO:0010165 8.62 ERCC1 TP53

Molecular functions related to Lung Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.62 ALK KEAP1 RRM1 TP53
2 transcription factor binding GO:0008134 9.33 KEAP1 NFE2L2 TP53
3 damaged DNA binding GO:0003684 9.26 ERCC1 TP53
4 TFIID-class transcription factor binding GO:0001094 8.96 ERCC1 TP53
5 disordered domain specific binding GO:0097718 8.8 KEAP1 RRM1 TP53

Sources for Lung Papillary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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