MCID: LPS019
MIFTS: 20

Lupus Erythematosus Tumidus

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Lupus Erythematosus Tumidus

MalaCards integrated aliases for Lupus Erythematosus Tumidus:

Name: Lupus Erythematosus Tumidus 52 58 71
Intermittent Cutaneous Lupus 52 58
Tumid Lupus Erythematosus 52

Classifications:

Orphanet: 58  
Rare skin diseases


External Ids:

ICD10 via Orphanet 33 L93.2
UMLS via Orphanet 72 C0406636
Orphanet 58 ORPHA90283
UMLS 71 C0406636

Summaries for Lupus Erythematosus Tumidus

NIH Rare Diseases : 52 Tumid erythematosus lupus is considered a rare type of chronic cutaneous lupus erythematosus. Cutaneous lupus erythematosus (CLE) can be divided into acute cutaneous lupus , subacute cutaneous lupus , and chronic cutaneous lupus . Tumid erythematosus lupus is characterized by smooth, non-scarring, pink- to violet-colored pimples (papules) on the skin without any other apparent skin changes, such as scarring. Patients with tumid lupus erythematosus usually do not have other symptoms of systemic lupus erythematosus or other types of cutaneous lupus erythematosus. The papules appear on sun-exposed areas of the face, upper back, V area of the neck, trunk, and arms, and more rarely on thighs and legs. They usually affect equally both sides of the body, but may affect only one side. Normally, the papules clear without leaving scars. The treatment is very effective in most cases, and may include sun protection, anti-malarials drugs , local corticosteroids , topical tacrolimus and light therapy .

MalaCards based summary : Lupus Erythematosus Tumidus, also known as intermittent cutaneous lupus, is related to lupus erythematosus and cutaneous lupus erythematosus. The drugs Alitretinoin and Dermatologic Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and b cells.

Related Diseases for Lupus Erythematosus Tumidus

Diseases related to Lupus Erythematosus Tumidus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)
# Related Disease Score Top Affiliating Genes
1 lupus erythematosus 11.0
2 cutaneous lupus erythematosus 10.8
3 discoid lupus erythematosus 10.7
4 chronic cutaneous lupus erythematosus 10.5
5 exanthem 10.3
6 systemic lupus erythematosus 10.3
7 urticaria 10.3
8 keratosis 10.3
9 skin disease 10.3
10 alopecia 10.3
11 subacute cutaneous lupus erythematosus 10.3
12 gastroesophageal reflux 10.2
13 antiphospholipid syndrome 10.2
14 scleredema adultorum 10.2
15 herpes zoster 10.2
16 catastrophic antiphospholipid syndrome 10.2
17 autoimmune disease 10.2
18 drug-induced lupus erythematosus 10.2
19 marginal zone b-cell lymphoma 10.2
20 lymphoma 10.2
21 dermatomycosis 10.2
22 chronic granulomatous disease 10.2
23 granuloma annulare 10.2
24 b-cell lymphoma 10.2
25 alopecia areata 10.2
26 primary cutaneous marginal zone b-cell lymphoma 10.2

Graphical network of the top 20 diseases related to Lupus Erythematosus Tumidus:



Diseases related to Lupus Erythematosus Tumidus

Symptoms & Phenotypes for Lupus Erythematosus Tumidus

Drugs & Therapeutics for Lupus Erythematosus Tumidus

Drugs for Lupus Erythematosus Tumidus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alitretinoin Approved, Investigational Phase 2 5300-03-8 449171 444795
2 Dermatologic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus Erythematosus: A Multicentre, Open-Label, Prospective Pilot Study Terminated NCT01407679 Phase 2 Alitretinoin

Search NIH Clinical Center for Lupus Erythematosus Tumidus

Genetic Tests for Lupus Erythematosus Tumidus

Anatomical Context for Lupus Erythematosus Tumidus

MalaCards organs/tissues related to Lupus Erythematosus Tumidus:

40
Skin, Testes, B Cells, Endothelial

Publications for Lupus Erythematosus Tumidus

Articles related to Lupus Erythematosus Tumidus:

(show top 50) (show all 72)
# Title Authors PMID Year
1
Lupus Erythematosus Tumidus Mimicking Primary Cutaneous Marginal Zone B-cell Lymphoma. 61
32556349 2020
2
Lupus Erythematosus Tumidus with Pseudolymphomatous Infiltrates: A Case Report. 61
32418941 2020
3
Refractory lupus erythematosus tumidus responsive to tildrakizumab. 61
31442369 2019
4
A unique presentation of lupus erythematosus tumidus in an adolescent boy. 61
31487347 2019
5
Reticular Erythematous Mucinosis: A Rare Cutaneous. 61
31032786 2019
6
Lupus erythematosus tumidus: clinical perspectives. 61
31632119 2019
7
A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus. 61
29668590 2018
8
Lupus erythematosus tumidus: Benign disease in children? 61
29473307 2018
9
A case of a focal oedematous reaction induced by rituximab overlying lupus erythematosus tumidus. 61
28691689 2017
10
An unusual clinical presentation of lupus erythematosus tumidus localized on the thigh. 61
28597962 2017
11
Rituximab in the treatment of recalcitrant generalized lupus erythematosus tumidus. 61
28598547 2017
12
Mepacrine as successful monotherapy for refractory Jessner-Kanof disease: still an important drug in the dermatologic armamentarium. 61
27686749 2017
13
Lupus erythematosus tumidus of the scalp masquerading as alopecia areata. 61
28319635 2017
14
Lupus erythematosus tumidus: A case and discussion of a rare entity in black patients. 61
27981226 2016
15
Ustekinumab-induced drug eruption resembling lymphocytic infiltration (of Jessner-Kanof) and lupus erythematosus tumidus. 61
26616890 2016
16
Smoking is highly associated with discoid lupus erythematosus and lupus erythematosus tumidus: analysis of 405 patients. 61
25411260 2015
17
Lupus erythematosus tumidus: a clinical and histological study of 25 cases. 61
25413356 2015
18
Reticular erythematous mucinosis: histopathological and immunohistochemical features of 25 patients compared with 25 cases of lupus erythematosus tumidus. 61
25087914 2015
19
Lupus erythematosus tumidus: a unique disease entity. 61
25285251 2014
20
Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects. 61
24626656 2014
21
Immunologic and genetic considerations of cutaneous lupus erythematosus: a comprehensive review. 61
23380467 2013
22
[Peculiarities of clinical picture and differential diagnostics of lupus erythematosus tumidus]. 61
23879059 2013
23
Cytokine and chemokine ligand expression in cutaneous lupus erythematosus. 61
22562806 2012
24
Low blood concentration of hydroxychloroquine in patients with refractory cutaneous lupus erythematosus: a French multicenter prospective study. 61
22508872 2012
25
[Lupus erythematosus tumidus: a clinical entity still being defined]. 61
21798482 2011
26
Lupus erythematosus tumidus with discoid lupus erythematosus-induced alopecia of the scalp. 61
22031650 2011
27
Photoprovocation in cutaneous lupus erythematosus: a multicenter study evaluating a standardized protocol. 61
21593767 2011
28
Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: a multicenter, randomized, double-blind, vehicle-controlled trial. 61
21501887 2011
29
Role of anti-tumor necrosis factor-alpha blockers in inducing lupus erythematosus tumidus in "rhupus syndrome". 61
21632691 2011
30
Lupus erythematosus tumidus. 61
21393980 2011
31
Lupus erythematosus tumidus: clinical, histopathological and serological aspects and therapy response of 21 patients. 61
21030340 2010
32
Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlates. 61
20693199 2010
33
Lupus erythematosus tumidus as a separate subtype of cutaneous lupus erythematosus. 61
20408831 2010
34
Lupus erythematosus tumidus is a separate subtype of cutaneous lupus erythematosus. 61
19712116 2010
35
[Drug-induced lupus erythematosus tumidus during treatment with adalimumab]. 61
19229504 2009
36
Bortezomib-induced lupus erythematosus tumidus. 61
19474161 2009
37
The 100th anniversary of lupus erythematosus tumidus. 61
19162244 2009
38
The different faces of cutaneous lupus erythematosus. 61
19357621 2009
39
Lupus erythematosus tumidus: response to antimalarial treatment in 36 patients with emphasis on smoking. 61
19289751 2009
40
[Reticular erythematous plaques]. 61
18806970 2009
41
Recruitment of plasmacytoid dendritic cells in ultraviolet irradiation-induced lupus erythematosus tumidus. 61
19016699 2009
42
Lupus erythematosus tumidus in Japan: a case report and a review of the literature. 61
19562251 2009
43
Comparison of histopathologic-clinical characteristics of Jessner's lymphocytic infiltration of the skin and lupus erythematosus tumidus: Multicenter study of 46 cases. 61
18083273 2008
44
Resistance to hydroxychloroquine due to smoking in a patient with lupus erythematosus tumidus. 61
17854374 2007
45
Lupus erythematosus tumidus induced by sex reassignment surgery. 61
17696264 2007
46
Lymphocytic infiltration (Jessner-Kanof): lupus erythematosus tumidus or a manifestation of borreliosis? 61
17573889 2007
47
Symmetric distribution of lupus erythematosus tumidus on the elbows. 61
16935815 2006
48
Lupus erythematosus tumidus: a series of 26 cases. 61
16700782 2006
49
Lupus erythematosus tumidus: an underestimated entity. 61
16761505 2006
50
Infliximab-induced lupus erythematosus tumidus in a patient with rheumatoid arthritis. 61
16415403 2006

Variations for Lupus Erythematosus Tumidus

Expression for Lupus Erythematosus Tumidus

Search GEO for disease gene expression data for Lupus Erythematosus Tumidus.

Pathways for Lupus Erythematosus Tumidus

GO Terms for Lupus Erythematosus Tumidus

Sources for Lupus Erythematosus Tumidus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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