MCID: LYM010
MIFTS: 41

Lymph Node Tuberculosis

Categories: Immune diseases, Infectious diseases
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Aliases & Classifications for Lymph Node Tuberculosis

MalaCards integrated aliases for Lymph Node Tuberculosis:

Name: Lymph Node Tuberculosis 11 14 16 71
King's Evil 11 43 71
Scrofula 11 71
Tuberculous Lymphadenopathy 11
Tuberculosis, Lymph Node 43
Tuberculous Adenitis 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4889
NCIt 49 C26896
SNOMED-CT 68 10893003
ICD10 31 A18.2
UMLS 71 C0036467 C0041316 C0242830

Summaries for Lymph Node Tuberculosis

Disease Ontology: 11 An extrapulmonary tuberculosis that is located in lymph node, and has symptom lymphadenopathy, has symptom fever, has symptom weight loss, has symptom fatigue, has symptom night sweats and has symptom cough.

MalaCards based summary: Lymph Node Tuberculosis, also known as king's evil, is related to tuberculous peritonitis and lymphadenitis, and has symptoms including fatigue, fever and cough. An important gene associated with Lymph Node Tuberculosis is MIR4536-1 (MicroRNA 4536-1), and among its related pathways/superpathways are T-cell activation SARS-CoV-2 and Hematopoietic Stem Cells and Lineage-specific Markers. The drugs Antiviral Agents and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include lymph node, adrenal cortex and thyroid.

Related Diseases for Lymph Node Tuberculosis

Diseases related to Lymph Node Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 660)
# Related Disease Score Top Affiliating Genes
1 tuberculous peritonitis 31.2 IFNG CRP ALB ADA
2 lymphadenitis 31.2 TNF IFNG CRP
3 skeletal tuberculosis 30.6 IFNG CRP
4 mycobacterium tuberculosis 1 30.4 TNF IFNG CRP CD4 ALB ADA
5 cat-scratch disease 30.3 CRP CD4
6 erythema nodosum 30.3 TNF IFNG CRP
7 pulmonary tuberculosis 30.2 TNF IFNG CRP ALB ADA
8 purpura 30.1 TNF IFNG CRP
9 cryptococcosis 30.1 TNF IFNG CD4
10 scleritis 30.1 TNF IFNG CRP
11 posterior scleritis 30.1 TNF IFNG CRP
12 interstitial lung disease 30.1 TNF IFNG CRP
13 osteomyelitis 30.1 TNF IFNG CRP
14 lymphangioma 30.1 TNF IFNG CD4
15 thyroiditis 30.1 TNF IFNG CRP
16 extrapulmonary tuberculosis 30.0 TNF IFNG CRP CD4 ALB ADA
17 mediastinitis 30.0 CRP CD4 ALB
18 parotitis 30.0 CRP CD4 ALB
19 spondylitis 29.9 TNF IFNG CRP
20 hemorrhagic disease 29.9 CRP CD4 ALB
21 cervical adenitis 29.9 TNF IFNG CRP CD4
22 colitis 29.9 TNF IFNG CRP CD4
23 keratoconjunctivitis 29.9 TNF IFNG ALB
24 hemorrhoid 29.9 TNF CRP ALB
25 paracoccidioidomycosis 29.9 TNF IFNG ALB
26 pleurisy 29.9 TNF IFNG CRP ADA
27 intracranial hypertension 29.8 TNF CRP ALB
28 peptic ulcer disease 29.8 TNF CRP ALB
29 immune deficiency disease 29.8 TNF IFNG CRP CD4 ADA
30 gout 29.7 TNF CRP ALB
31 sarcoidosis 1 29.7 TNF IFNG CRP CD4 ALB ADA
32 intestinal obstruction 29.7 TNF CRP ALB
33 multidrug-resistant tuberculosis 29.7 TNF IFNG CD4 ALB
34 demyelinating polyneuropathy 29.7 TNF CRP CD4 ALB
35 cellulitis 29.7 TNF CRP CD4 ALB
36 pneumonia 29.7 TNF IFNG CRP ALB
37 syphilis 29.7 TNF CRP CD4 ALB
38 bronchitis 29.7 TNF CRP ALB
39 pleural tuberculosis 29.7 TNF IFNG CRP CD4 ADA
40 alcohol use disorder 29.6 TNF CRP CD4 ALB
41 miliary tuberculosis 29.6 TNF IFNG CRP CD4 ALB ADA
42 otitis media 29.6 TNF IFNG CRP ALB
43 neutropenia 29.6 TNF IFNG CRP ALB
44 pancytopenia 29.6 IFNG CRP CD4 ALB
45 abdominal tuberculosis 29.5 TNF IFNG CRP CD4 ALB ADA
46 pneumocystosis 29.4 TNF IFNG CRP CD4 ALB
47 temporal arteritis 29.4 TNF IFNG CRP CD4 ALB
48 skin disease 29.4 TNF IFNG CRP CD4 ALB
49 thrombocytopenia 29.4 TNF IFNG CRP CD4 ALB
50 crohn's disease 29.3 TNF IFNG CRP CD4 ALB

Graphical network of the top 20 diseases related to Lymph Node Tuberculosis:



Diseases related to Lymph Node Tuberculosis

Symptoms & Phenotypes for Lymph Node Tuberculosis

Symptoms:

11
  • fatigue
  • fever
  • cough
  • weight loss
  • lymphadenopathy
  • night sweats

Drugs & Therapeutics for Lymph Node Tuberculosis

Drugs for Lymph Node Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antiviral Agents
2 Anti-Infective Agents
3 Fluorodeoxyglucose F18
4 Antimetabolites
5 Deoxyglucose

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Diagnosis of Mediastinal Tuberculous Lymphadenopathy by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) Unknown status NCT01121432
2 Evaluation of Positron Emission Tomography in Extrapulmonary Tuberculosis Completed NCT01613196
3 Immunology Dysregulation in Lymphadenitis Tuberculosis : An Observational Study Using Patient' Block Paraffins 2019 Until 2021 Completed NCT05202548

Search NIH Clinical Center for Lymph Node Tuberculosis

Cochrane evidence based reviews: king's evil

Genetic Tests for Lymph Node Tuberculosis

Anatomical Context for Lymph Node Tuberculosis

Organs/tissues related to Lymph Node Tuberculosis:

FMA: Lymph Node
MalaCards : Lymph Node, Adrenal Cortex, Thyroid, Lung, Skin, Salivary Gland, T Cells

Publications for Lymph Node Tuberculosis

Articles related to Lymph Node Tuberculosis:

(show top 50) (show all 1177)
# Title Authors PMID Year
1
Thyroid tuberculosis diagnosed as papillary thyroid carcinoma with fever of unknown origin. 62
34657776 2022
2
The diagnostic and prognostic value of plasma circulating circNUP98 for nasopharyngeal carcinoma. 62
36330641 2022
3
Retrospective observational study to compare Xpert MTB/RIF assay with other diagnostic tests in lymph node tuberculosis. 62
36412467 2022
4
Botanical Description, Traditional Uses, Phytochemistry, and Pharmacology of the Genus Artabotrys: A Review. 62
36222471 2022
5
The royal touch: Scrofula and defining monarchy. 62
36202382 2022
6
Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children. 62
36065889 2022
7
Xpert MTB/RIF Assay for the Diagnosis of Lymph Node Tuberculosis in Children: A Systematic Review and Meta-Analysis. 62
35956230 2022
8
Heterotopic squamous epithelial inclusion cyst in a cervical lymph node in a child: a case report and literature review. 62
35958003 2022
9
Diagnosis and Management of Occult Cervical Tuberculous Lymphadenopathy. 62
34842464 2022
10
An atypical presentation of tuberculous gumma heralding a diagnosis of lymph node tuberculosis: Hindsight is 20/20. 62
35542318 2022
11
Disseminated tuberculosis following invasive procedures for peripancreatic lymph node tuberculosis with portal vein obstruction: a case report. 62
35334085 2022
12
An Adult Female Presenting With "Scrofula-Tubercular Lymphadenitis" a Rare Encounter: A Case Report. 62
35785004 2022
13
A Novel Approach of Targeting Linezolid Nanoemulsion for the Management of Lymph Node Tuberculosis. 62
35571844 2022
14
Primary mediastinal lymph node tuberculosis diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration: Literature review and case report. 62
35345566 2022
15
Asymptomatic gastric tuberculosis in the gastric body mimicking an isolated microscopic erosion: A rare case report. 62
35212291 2022
16
Bilateral optic neuritis as a first presentation of lymph node tuberculosis. 62
34321330 2022
17
Prunella vulgaris L. - A Review of its Ethnopharmacology, Phytochemistry, Quality Control and Pharmacological Effects. 62
35814234 2022
18
Chinese endemic medicinal plant Bolbostemma paniculatum (Maxim.) Franquet: A comprehensive review. 62
36160391 2022
19
Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child. 62
35663608 2022
20
A case of paradoxical reaction after treatment of generalized tuberculous lymphadenopathy in a peritoneal dialysis patient. 62
35308055 2022
21
Research of childhood tuberculosis in suspected populations by molecular methods: A multicenter study in China. 62
36339333 2022
22
The Role of Core Needle Biopsy Pathology Combined with Molecular Tests in the Diagnosis of Lymph Node Tuberculosis. 62
35140479 2022
23
Dominant expansion of CD4+, CD8+ T and NK cells expressing Th1/Tc1/Type 1 cytokines in culture-positive lymph node tuberculosis. 62
35617254 2022
24
Some Manifestations of Tuberculosis in Otorhinolaryngology - Case Series and a Short Review of Related Data from South-Eastern Europe. 62
35668856 2022
25
Case Report: Primary Mediastinal Large B-Cell Lymphoma Invasion of Extranodal Thyroid Tissue Mimicking Tuberculosis and Confounded by Similar Ultrasonic Appearance. 62
35664739 2022
26
Analysis of misdiagnosis and 18F-FDG PET/CT findings of lymph node tuberculosis. 62
35694951 2022
27
Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis. 62
35251730 2022
28
Lymph Node Tuberculosis in Otolaryngological Practice: A Study of 68 Cases at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso. 62
35605587 2022
29
Ultrasound-Based Radiomics Can Classify the Etiology of Cervical Lymphadenopathy: A Multi-Center Retrospective Study. 62
35656511 2022
30
Royal disease (Vasilios nósos): Substantiating one of the names of tuberculosis in Greek, from "Atakta" dictionary by Adamantios Korais, (1832-1835). 62
35350256 2022
31
Rare presentation of tuberculous hypertrophic pachymeningitis diagnosed by a biopsy of abdominal lymphadenopathy. 62
35320986 2022
32
Historical Review of Ethnopharmacology in Karelia (1850s-2020s): Herbs and healers. 62
34496265 2022
33
A proposed CT classification of progressive lung parenchymal injury complicating pediatric lymphobronchial tuberculosis: From reversible to irreversible lung injury. 62
34515414 2021
34
Lymph Node Tuberculosis With Erythema Nodosum and Bone Nodules on Magnetic Resonance Imaging. 62
32925446 2021
35
Disseminated lymph node tuberculosis after splenectomy: an unusual case report in an adolescent. 62
34819021 2021
36
Real-time next-generation sequencing on shell-vial culture to contribute to diagnosis of lymphatic tuberculosis: a case report. 62
34343856 2021
37
Miliary brain tuberculosis in an infant. 62
34401018 2021
38
Utility of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of tuberculous lymphadenitis compared to GeneXpert in a tertiary health care center in Northern Odisha, India. 62
34752310 2021
39
Mandibular tuberculosis fortuitously discovered after surgical resection of an ameloblastoma: A case report. 62
34583263 2021
40
BCG re-vaccination in Malawi: 30-year follow-up of a large, randomised, double-blind, placebo-controlled trial. 62
34534489 2021
41
A review of Cremastra appendiculata (D.Don) Makino as a traditional herbal medicine and its main components. 62
34166737 2021
42
[Analysis on specific effect of acupoints at the upper arms in treatment of scrofula and goiter]. 62
34628753 2021
43
Intrahepatic arterial pseudoaneurysm secondary to lymph node tuberculosis. 62
34455994 2021
44
Magnetic resonance imaging in response assessment of mediastinal tuberculous lymphadenopathy: Going beyond size. 62
34472520 2021
45
Tuberculosis lymph node granulomas: using transcriptomics to discover immunopathology paradigms and guide host-directed therapy. 62
34338227 2021
46
Diagnostic Performance of EUS-Guided Sampling in Indeterminate Radiological Diagnosis of Pancreatic Disease and Intra-Abdominal Lymphadenopathy. 62
34501294 2021
47
Value of Serum Adenosine Deaminase (ADA) in Distinguishing between Tuberculous and Non-tuberculous Lymphadenopathies. 62
34226459 2021
48
Outcome of lymph node tuberculosis management with conventional treatment with and without prednisolone. 62
33427091 2021
49
[Clinical analysis of lateral cervical approach in the treatment of cervical lymphatic tuberculosis complicated with parapharyngeal space abscess]. 62
34304486 2021
50
Vulval lymphangiectasia in pregnancy-a rare case report. 62
33779006 2021

Variations for Lymph Node Tuberculosis

Expression for Lymph Node Tuberculosis

Search GEO for disease gene expression data for Lymph Node Tuberculosis.

Pathways for Lymph Node Tuberculosis

GO Terms for Lymph Node Tuberculosis

Biological processes related to Lymph Node Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of amyloid-beta clearance GO:1900222 9.62 TNF IFNG
2 negative regulation of lipid storage GO:0010888 9.56 TNF CRP
3 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.46 TNF IFNG
4 positive regulation of nitrogen compound metabolic process GO:0051173 9.26 TNF IFNG
5 positive regulation of vitamin D biosynthetic process GO:0060557 8.92 TNF IFNG

Sources for Lymph Node Tuberculosis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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