MCID: LYM010
MIFTS: 36

Lymph Node Tuberculosis

Categories: Immune diseases, Infectious diseases

Aliases & Classifications for Lymph Node Tuberculosis

MalaCards integrated aliases for Lymph Node Tuberculosis:

Name: Lymph Node Tuberculosis 12 15 17 71
King's Evil 12 43 71
Scrofula 12 71
Tuberculous Lymphadenopathy 12
Tuberculosis, Lymph Node 43
Tuberculous Adenitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4889
NCIt 49 C26896
SNOMED-CT 67 10893003
ICD10 32 A18.2
UMLS 71 C0036467 C0041316 C0242830

Summaries for Lymph Node Tuberculosis

Disease Ontology : 12 An extrapulmonary tuberculosis that is located in lymph node, and has symptom lymphadenopathy, has symptom fever, has symptom weight loss, has symptom fatigue, has symptom night sweats and has symptom cough.

MalaCards based summary : Lymph Node Tuberculosis, also known as king's evil, is related to extrapulmonary tuberculosis and abdominal tuberculosis, and has symptoms including fatigue, fever and weight loss. An important gene associated with Lymph Node Tuberculosis is SP110 (SP110 Nuclear Body Protein), and among its related pathways/superpathways are Cytokines and Inflammatory Response and IL12 signaling mediated by STAT4. The drugs Antiviral Agents and Antimetabolites have been mentioned in the context of this disorder. Affiliated tissues include lymph node, lung and skin.

Related Diseases for Lymph Node Tuberculosis

Diseases related to Lymph Node Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 170)
# Related Disease Score Top Affiliating Genes
1 extrapulmonary tuberculosis 30.7 SP110 IFNG CD4
2 abdominal tuberculosis 30.6 IFNG CD4
3 miliary tuberculosis 30.4 IFNG CD4
4 multidrug-resistant tuberculosis 30.3 IFNG CD4
5 pleural tuberculosis 30.1 IFNG CD4
6 cryptococcosis 29.8 IFNG CD4
7 intestinal tuberculosis 29.6 LTA4H IFNG CD4
8 mesenteric lymphadenitis 11.2
9 tuberculous peritonitis 11.2
10 mycobacterium tuberculosis 1 10.9
11 lymphadenitis 10.5
12 pulmonary tuberculosis 10.5
13 panophthalmitis 10.3 IFNG CD4
14 chronic graft versus host disease 10.3 IFNG CD4
15 pericardial tuberculosis 10.3 IFNG CD4
16 neuroretinitis 10.3 IFNG CD4
17 nickel allergic contact dermatitis 10.2 IFNG CD4
18 gastrointestinal tuberculosis 10.2 IFNG CD4
19 oral tuberculosis 10.2 IFNG CD4
20 laryngeal tuberculosis 10.2 IFNG CD4
21 lung abscess 10.2 IFNG CD4
22 sporotrichosis 10.2 IFNG CD4
23 corticosteroid allergy 10.2 IFNG CD4
24 mucocutaneous leishmaniasis 10.2 IFNG CD4
25 chorioretinitis 10.2 IFNG CD4
26 choroiditis 10.2 IFNG CD4
27 gastroduodenitis 10.2 ZBTB32 CD4
28 fungal meningitis 10.2 IFNG CD4
29 tuberculoid leprosy 10.2 IFNG CD4
30 central nervous system tuberculosis 10.2 LTA4H CD4
31 macs syndrome 10.2 IFNG CD4
32 mucormycosis 10.2 IFNG CD4
33 central nervous system vasculitis 10.2 IFNG CD4
34 strongyloidiasis 10.2 IFNG CD4
35 primary systemic mycosis 10.2 IFNG CD4
36 cytomegalovirus retinitis 10.2 IFNG CD4
37 campylobacteriosis 10.1 IFNG EID2
38 autoimmune gastritis 10.1 IFNG CD4
39 sarcoidosis 1 10.1
40 obstructive jaundice 10.1
41 lichen disease 10.1 IFNG CD4
42 histoplasmosis 10.1 IFNG CD4
43 multicentric castleman disease 10.1 IFNG CD4
44 cryptococcal meningitis 10.1 IFNG CD4
45 hypersplenism 10.1 IFNG CD4
46 folliculitis 10.1 IFNG CD4
47 chondrosarcoma 10.0
48 osteogenic sarcoma 10.0
49 langerhans cell histiocytosis 10.0
50 human immunodeficiency virus type 1 10.0

Graphical network of the top 20 diseases related to Lymph Node Tuberculosis:



Diseases related to Lymph Node Tuberculosis

Symptoms & Phenotypes for Lymph Node Tuberculosis

Symptoms:

12
  • fatigue
  • fever
  • weight loss
  • cough
  • lymphadenopathy
  • night sweats

Drugs & Therapeutics for Lymph Node Tuberculosis

Drugs for Lymph Node Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antiviral Agents
2 Antimetabolites
3 Deoxyglucose
4 Anti-Infective Agents
5 Fluorides
6 Fluorodeoxyglucose F18

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Diagnosis of Mediastinal Tuberculous Lymphadenopathy by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) Unknown status NCT01121432
2 Evaluation of Positron Emission Tomography in Extrapulmonary Tuberculosis Completed NCT01613196
3 Value of EBUS-TBNA for Mediastinal Lymph Nodes in Non-small Cell Lung Cancer in a Tuberculosis-endemic Country Completed NCT01156623
4 Significance of Endoscopic Ultrasonography Guided Transbronchial Lymph Node Biopsy (TBNA) and Ultrasound Elastography in Lymph Node Active, not recruiting NCT03391557
5 Role of EBUS-TBNA (Endobronchial Ultrasound Transbronchial Needle Aspiration- in Diagnosing Tuberculosis in Mediastinal and/or Hilar Lymph Nodes Suspended NCT01350674

Search NIH Clinical Center for Lymph Node Tuberculosis

Cochrane evidence based reviews: king's evil

Genetic Tests for Lymph Node Tuberculosis

Anatomical Context for Lymph Node Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Lymph Node Tuberculosis:

19
Lymph Node

MalaCards organs/tissues related to Lymph Node Tuberculosis:

40
Lymph Node, Lung, Skin, Breast, Pituitary, Testes, Thyroid

Publications for Lymph Node Tuberculosis

Articles related to Lymph Node Tuberculosis:

(show top 50) (show all 603)
# Title Authors PMID Year
1
Identification of Differentially Expressed Genes Associated with Lymph Node Tuberculosis by the Bioinformatic Analysis Based on a Microarray. 61
31460784 2020
2
Bacteriologically Determined De Novo Tuberculosis during Tumor Necrosis Factor-α Inhibitor Therapy. 61
31434822 2019
3
Evaluation of the Yield of Histopathology in the Diagnosis of Lymph Node Tuberculosis in Morocco, 2017: Cross-Sectional Study. 61
31599732 2019
4
[Study on the sensitivity of multi-slice spiral CT in diagnosis of lymph node metastasis in different lymph node stations of gastric cancer]. 61
31630498 2019
5
[Febrile rhabdomyolysis revealing an abdominal lymph node tuberculosis in an immunocompetent patient]. 61
31548118 2019
6
Fine needle non-aspiration cytology for the diagnosis of cervical lymph node tuberculosis: a single center experience. 61
30017875 2019
7
A politics of the senses: the political role of theKing's-Evil in Richard Wiseman's Severall Chirurgicall Treatises. 61
29970613 2019
8
Cartridge based nucleic acid amplification test is superior in diagnosing lymphnode tuberculosis. 61
31439187 2019
9
Enhanced Mycobacterial Antigen-Induced Pro-Inflammatory Cytokine Production in Lymph Node Tuberculosis. 61
30994092 2019
10
[One case of tuberculous otitis media with cervical lymph node tuberculosis in child]. 61
31262113 2019
11
DOCK8 deficiency with mediastinal lymph node tuberculosis. 61
31016565 2019
12
Persistent Anemia Combined Increased Serum Sedimentation (ESR) for More Than Two Years Firstly Misdiagnosed as Lymphoma Ultimately Confirmed Systemic Lymph Nodes Tuberculosis by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Pathology: a Case Report and Literature Review. 61
30868854 2019
13
Comparison of the Microwave-Heated Ziehl-Neelsen Stain and Conventional Ziehl-Neelsen Method in the Detection of Acid-Fast Bacilli in Lymph Node Biopsies. 61
30976331 2019
14
The Application of Xpert Mycobacterium tuberculosis/Rifampicin, Quantitative Polymerase Chain Reaction and High Resolution Melting Curve in the Diagnosis of Superficial Lymph Node TB. 61
31333119 2019
15
Diagnostic Accuracy of the Xpert MTB/RIF Assay for Lymph Node Tuberculosis: A Systematic Review and Meta-Analysis. 61
31236407 2019
16
Hodgkin's lymphoma with marked granulomatous reaction: a diagnostic pitfall. 61
31934112 2019
17
An Overlooked Eighteenth-Century Scrofula Pamphlet: Changing Forms and Changing Readers, 1760-1824. 61
31700650 2019
18
Impact of Mycobacterium tuberculosis complex lineages as a determinant of disease phenotypes from an immigrant rich moderate tuberculosis burden country. 61
30587190 2018
19
Immune activation and regulatory T cells in Mycobacterium tuberculosis infected lymph nodes. 61
30409122 2018
20
High IL-6 and VEGF-A levels correlate with delayed wound healing in cervical lymph node tuberculosis patients. 61
30236193 2018
21
[Culture proven extra pulmonary tuberculosis: drug susceptibility and genetic profile analysis]. 61
30479231 2018
22
Pituitary tuberculosis presented with pituitary coma. 61
30430535 2018
23
Man with bilateral inguinal lymphadenopathy. 61
30030235 2018
24
Endothelial lineage-specific interaction of Mycobacterium tuberculosis with the blood and lymphatic systems. 61
30029892 2018
25
Vacuum-assisted closure therapy of paradoxical reaction in tuberculous lymphadenopathy caused by Mycobacterium africanum. 61
29330673 2018
26
Bilateral central retinal artery occlusion as presenting manifestation of human immunodeficiency virus infection. 61
29480272 2018
27
Pathology of lymph node tuberculosis in Yaounde: diagnostic agreement based on the Kappa coefficient. 61
30455787 2018
28
Clinical efficacy of short-course chemotherapy combined with topical injection therapy in treatment of superficial lymph node tuberculosis. 61
29299116 2017
29
Loss of vision and hearing in a case of cervical lymph node tuberculosis: A rare paradoxical reaction. 61
29099011 2017
30
[Endobronchial Ultrasound (EBUS) - an Update 2017]. 61
29139101 2017
31
[Diagnosis value with Xpert Mtb/RIF assay for cervical tuberculous lymphadenitis]. 61
29798226 2017
32
Pattern and predictors of paradoxical response in patients with peripheral lymph node tuberculosis. 61
29135395 2017
33
Primary peripancreatic lymph node tuberculosis as a differential diagnosis of pancreatic neoplasia. 61
28506074 2017
34
Clinical usefulness of 18F-FDG PET/CT for initial staging and assessment of treatment efficacy in patients with lymph node tuberculosis. 61
28426991 2017
35
Lymph node tuberculosis mimicking malignancy on 18F-FDG PET/CT in two patients: A case report. 61
28587415 2017
36
Spontaneous chylothorax revealing a mediastinal and abdominal lymph node tuberculosis. 61
28410698 2017
37
The history of tuberculosis: from the first historical records to the isolation of Koch's bacillus. 61
28515626 2017
38
Tuberculosis After Renal Transplant. 61
28260468 2017
39
Miliary tuberculosis infection during hepatitis C treatment with sofosbuvir and ledipasvir plus ribavirin. 61
28217253 2017
40
Bronchopleural and pleurocutaneous fistula in HIV patient with pulmonary tuberculosis. 61
28725561 2017
41
Tuberculosis infection in children with proteinuria/nephrotic syndrome. 61
29204099 2017
42
Paradoxical reaction associated with cervical lymph node tuberculosis: predictive factors and therapeutic management. 61
27810522 2017
43
Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First Steps. 61
27742638 2016
44
[Recurrent fever, hepatosplenomegaly and eosinophilia in a boy]. 61
27817782 2016
45
A case series and review of Poncet's disease, and the utility of current diagnostic criteria. 61
26354099 2016
46
[A CASE OF LYMPH NODE TUBERCULOSIS ASSOCIATED WITH A FLUID-FILLED MASS IN THE THORACIC WALL DUE TO A PARADOXICAL RESPONSE TO THERAPY]. 61
30646456 2016
47
[Tuberculoma associated with bilateral posterior scleritis secondary to lymph node tuberculosis: A case report]. 61
27157682 2016
48
The King's Evil and the Royal Touch: the medical history of scrofula. 61
27155172 2016
49
Diagnostic performance of interferon-γ release assay for lymph node tuberculosis. 61
26971638 2016
50
Add-on prednisolone in the management of cervical lymph node tuberculosis. 61
27451818 2016

Variations for Lymph Node Tuberculosis

Expression for Lymph Node Tuberculosis

Search GEO for disease gene expression data for Lymph Node Tuberculosis.

Pathways for Lymph Node Tuberculosis

Pathways related to Lymph Node Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.42 IFNG CD4
2 10.07 IFNG CD4

GO Terms for Lymph Node Tuberculosis

Sources for Lymph Node Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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