Lymphangioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: LYM022 MIFTS: 52	Lymphangioma Categories: Cancer diseases, Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs Download Expand all tables

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Aliases & Classifications for Lymphangioma

MalaCards integrated aliases for Lymphangioma:

Name: Lymphangioma ¹² ³⁷ ²⁹ ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Congenital Lymphangioma ¹²

Benign Lymphangioma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Neoplasms

Benign neoplasms

Haemangioma and lymphangioma, any site

Lymphangioma, any site

External Ids:

Disease Ontology ¹² DOID:1475

ICD10 ³³ D18.1

ICD9CM ³⁵ 228.1

MeSH ⁴⁴ D008202

NCIt ⁵⁰ C8965

SNOMED-CT ⁶⁸ 154625006 189200000 189875000 more

KEGG ³⁷ H01471

UMLS ⁷³ C0024221

Sources

Summaries for Lymphangioma

MalaCards based summary : Lymphangioma, also known as congenital lymphangioma, is related to orbital lymphangioma and lymphatic malformations. An important gene associated with Lymphangioma is FLT4 (Fms Related Tyrosine Kinase 4), and among its related pathways/superpathways are TGF-Beta Pathway and Focal Adhesion. The drugs Picibanil and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include pancreas, tongue and lymph node, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : ⁷⁶ Lymphangiomas are malformations of the lymphatic system characterized by lesions that are thin-walled... more...

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Related Diseases for Lymphangioma

Diseases related to Lymphangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 219)

#	Related Disease	Score	Top Affiliating Genes
1	orbital lymphangioma	34.1	FLT4 PDPN
2	lymphatic malformations	33.2	FLT4 PROX1
3	capillary lymphangioma	33.0	HBA1 PROX1
4	hemangioendothelioma	30.7	FLT4 KDR
5	epithelioid hemangioendothelioma	30.3	KDR VEGFA
6	hydrocele	30.1	FLT4 VEGFA
7	gorham's disease	30.1	FLT4 IFNA2 VEGFC
8	kaposiform hemangioendothelioma	30.1	FLT4 KDR PROX1
9	hemangioma	28.3	ACTC1 FLT4 KDR PDPN PROX1 VEGFA
10	lymphangiosarcoma	27.2	FLT4 HBA1 PDPN PROX1 VEGFA VEGFC
11	cystic lymphangioma	12.3
12	abdominal cystic lymphangioma	12.3
13	microcystic lymphatic malformation	12.1
14	cavernous lymphangioma	12.1
15	colonic lymphangioma	12.1
16	primary laryngeal lymphangioma	12.0
17	nuchal bleb, familial	11.7
18	cobb syndrome	11.3
19	lymphangiomatosis	11.2
20	mixed cystic lymphatic malformation	11.2
21	diffuse lymphatic malformation	11.1
22	multiple enchondromatosis, maffucci type	10.9
23	infantile myofibromatosis	10.9
24	mucinous cystadenocarcinoma of the pancreas	10.7	PDPN VEGFC
25	hemangioma, capillary infantile	10.6	FLT4 KDR
26	hemifacial spasm	10.6	FLT4 VEGFA
27	infiltrating angiolipoma	10.6	VEGFA VEGFC
28	angiokeratoma circumscriptum	10.5	KDR VEGFA
29	discoid lupus erythematosus	10.5	IFNA2 PDPN
30	radiation proctitis	10.5	KDR VEGFA
31	kuhnt-junius degeneration	10.5	KDR VEGFA
32	pulmonary vein stenosis	10.4	ACTC1 KDR
33	congenital lymphedema	10.4	FLT4 PDPN VEGFC
34	intravascular papillary endothelial hyperplasia	10.4	ACTC1 VEGFA
35	acute hemorrhagic leukoencephalitis	10.4	KDR VEGFA
36	miliaria	10.4	HBA1 PDPN
37	pyogenic granuloma	10.4	ACTC1 VEGFA
38	leukostasis	10.4	KDR VEGFA
39	senile angioma	10.4	HBA1 KDR
40	carcinoid syndrome	10.4	IFNA2 VEGFA
41	hemangioma of liver	10.4	HBA1 IFNA2
42	pediatric angiosarcoma	10.4	HBA1 VEGFA
43	mediastinitis	10.3
44	cavernous hemangioma	10.3
45	pneumatosis cystoides intestinalis	10.3	HBA1 PDPN
46	hypoglycemic coma	10.3	HBA1 VEGFA
47	glomeruloid hemangioma	10.3	HBA1 VEGFA
48	spindle cell sarcoma	10.3	ACTC1 VEGFA
49	pancreatitis	10.3
50	hemangioma-thrombocytopenia syndrome	10.3

Graphical network of the top 20 diseases related to Lymphangioma:

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Symptoms & Phenotypes for Lymphangioma

MGI Mouse Phenotypes related to Lymphangioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	10.06	PDPN ACTC1 PROX1 FLT4 SERPINF1 VEGFA
2	homeostasis/metabolism	MP:0005376	9.92	KDR PDPN ACTC1 PROX1 FLT4 VEGFA
3	immune system	MP:0005387	9.86	KDR PDPN PROX1 FLT4 SERPINF1 VEGFA
4	digestive/alimentary	MP:0005381	9.85	PDPN PROX1 FLT4 SERPINF1 VEGFA IFNG
5	liver/biliary system	MP:0005370	9.55	KDR PROX1 FLT4 VEGFA IFNG
6	muscle	MP:0005369	9.5	PDPN ACTC1 PROX1 FLT4 VEGFA IFNG
7	normal	MP:0002873	9.1	KDR ACTC1 PROX1 FLT4 VEGFA IFNG

Sources

Drugs & Therapeutics for Lymphangioma

Drugs for Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Picibanil

Phase 4,Phase 2,Phase 3

Octreotide

Approved, Investigational

Phase 2

83150-76-9

383414 6400441

Synonyms:

(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa

10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

79517-01-4 (acetate salt)

83150-76-9

AC1L1GVU

AC1L8LCD

AC1L9M4X

C07306

C5H12O2.C4H10

CHEBI:427278

CHEBI:611465

CHEMBL1680

CID383414

CID448601

CID54374

Compound 201 995

Compound 201995

Compound 201-995

D00442

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide

DRG-0115

HMS2090C09

HS-2020

L000453

L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*

Longastatin

LS-177735

LS-187135

NCGC00181796-01

nchembio.184-comp3

NCI60_025753

Octreotida

Octreotida [Spanish]

Octreotide

Octreotide (USAN/INN)

Octreotide [USAN:INN:BAN]

Octreotide acetate

Octreotide acetate salt

Octreotide Acetate Salt

Octreotide-LAR

Octreotidum

Octreotidum [Latin]

Octrotide

SAN 201-995

Sandostatin

Sandostatine

Sandoz 201 995

Sandoz 201995

Sandoz 201-995

SM 201-995

SMS 201-995

SMS-201-995

UNII-RWM8CCW8GP

zacycloicosane-4-carboxamide acetate

Everolimus

Approved

Phase 2

159351-69-6

6442177

Synonyms:

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

001, RAD

07741_FLUKA

159351-69-6

40-O-(2-hydroxyethyl)-rapamycin

40-O-(2-Hydroxyethyl)-rapamycin

42-O-(2-Hydroxyethyl)rapamycin

Afinitor

Certican

CERTICAN(R)

CHEMBL1201755

D02714

DB01590

everolimus

Everolimus

Everolimus (JAN/USAN/INN)

Everolimus [USAN]

LS-143292

MolPort-003-847-342

MolPort-003-925-588

NCGC00167512-01

NVP-RAD-001

RAD 001

RAD, SDZ

RAD001

RAD-001

RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus

RAD-001C

S1120_Selleck

SDZ RAD

SDZ-RAD

UNII-9HW64Q8G6G

Zortress

Miconazole

Approved, Investigational, Vet_approved

Phase 2

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin iv

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (tn)

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Sirolimus

Approved, Investigational

Phase 2

53123-88-9

5284616 6436030 46835353

Synonyms:

(-)-rapamycin

(-)-Rapamycin

1fkb

1pbk

23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine

23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine

23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29

3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

53123-88-9

A422989, NSC226080

AC1L1JH9

AC1L7MJ9

AC1L9ZMV

AC-722

Ambotz53123-88-9

Antibiotic AY 22989

AY 22989

AY22989

AY-22989

BIDD:PXR0165

Bio1_000293

Bio1_000782

Bio1_001271

Bio2_000375

Bio2_000855

BiomolKI2_000084

C07909

C51H79NO13

CBiol_002007

CCRIS 9024

CHEBI:100923

CHEBI:9168

CHEMBL413

CID10213190

CID10795871

CID11949238

CID11959112

CID313006

CID478951

CID5040

CID5284616

CID5358081

CID5374464

CID5460439

CID5497196

CID5924240

CID6436030

CID6610270

CID6610346

CID6711160

CID6713081

CID9833581

CID9854379

CID9854380

CID9962926

CID9962928

D00753

DB00877

DE-109

DivK1c_006936

FT-0082351

heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy

HMS2089A21

HSDB 7284

KBio1_001880

KBio2_000410

KBio2_002978

KBio2_005546

KBio3_000779

KBio3_000780

KBioGR_000410

KBioSS_000410

LCP-Siro

LMPK06000003

LS-143290

MLS000028373

MolMap_000043

MolPort-003-959-433

MS-R001

NCGC00021305-05

nchembio.100-comp4

nchembio.2007.42-comp2

nchembio.79-comp1

nchembio762-comp1

nchembio883-comp3

NCI60_001851

NCIMech_000355

NSC 226080

NSC226080

Perceiva

QTL1_000069

R0395_SIAL

R0395_SIGMA

RAP

RAPA

Rapammune

Rapamune

Rapamune (TN)

rapamycin

Rapamycin

Rapamycin (TN)

Rapamycin C-7, analog 4

Rapamycin from Streptomyces hygroscopicus

Rapamycin Immunosuppressant Drug

RPM

S1039_Selleck

SIIA 9268A

SILA 9268A

SILA9268A

sirolimus

Sirolimus

sirolimús

Sirolimus (RAPAMUNE)

Sirolimus (USAN/INN)

Sirolimus [USAN:BAN:INN]

Sirolimus, Rapamune,Rapamycin

sirolimusum

SMP1_000255

SMR000058564

SpecPlus_000840

UNII-W36ZG6FT64

UNM-0000358684

Wy 090217

WY-090217

Citric Acid

Approved, Nutraceutical, Vet_approved

Phase 1, Phase 2,Phase 2

77-92-9

311

Synonyms:

2-Hydroxy-1,2,3-propanetricarboxylate

2-Hydroxy-1,2,3-propanetricarboxylic acid

2-Hydroxytricarballylate

2-Hydroxytricarballylic acid

3-Carboxy-3-hydroxypentane-1,5-dioate

3-Carboxy-3-hydroxypentane-1,5-dioic acid

Acid monohydrate, citric

Aciletten

Anhydrous citrate

Anhydrous citric acid

beta-Hydroxytricarballylate

beta-Hydroxytricarballylic acid

Chemfill

Citraclean

Citrate

Citretten

Citric acid monohydrate

Citric acid, anhydrous

Citric Acid, Anhydrous

Citro

Citronensaeure

Citronensäure

e 330

e330

H3Cit

Hydrocerol a

Kyselina citronova

Monohydrate, citric acid

Suby g

Uralyt u

uro-Trainer

Phosphodiesterase 5 Inhibitors

Phase 1, Phase 2,Phase 2

Phosphodiesterase Inhibitors

Phase 1, Phase 2,Phase 2

Sildenafil Citrate

Phase 1, Phase 2,Phase 2

171599-83-0

Vasodilator Agents

Phase 1, Phase 2,Phase 2

Antineoplastic Agents, Hormonal

Phase 2

Gastrointestinal Agents

Phase 2

Anti-Bacterial Agents

Phase 2

Antibiotics, Antitubercular

Phase 2

Antifungal Agents

Phase 2

Anti-Infective Agents

Phase 2

Immunosuppressive Agents

Phase 2

Citrate

Nutraceutical

Phase 1, Phase 2,Phase 2

Marimastat

Approved, Investigational

Phase 1

154039-60-8

119031

Synonyms:

(2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide

(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic acid

(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoyl)propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acid

(2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide

15039-60-8

154039-60-8

AC1L3O2N

BB 2516

BB-2516

C100342

C15H29N3O5

CHEBI:50662

CHEMBL279785

CID119031

D03795

DB00786

LS-45634

Marimastat

Marimastat (USAN/INN)

Marimastat [USAN]

UNII-D5EQV23TDS

Selenium

Approved, Investigational, Vet_approved

Phase 1

7782-49-2

Synonyms:

Se(2+)

Se2+

Selanediide

Selen

Selenide

Selenide(2-)

Selenio

Sélénium

Selenium dication

Selenium elemental

Selenium ion (se2+)

Selenium metallicum

Selenium, elemental

Antioxidants

Phase 1

Micronutrients

Phase 1

Protective Agents

Phase 1

Trace Elements

Phase 1

Pancrelipase

Approved, Investigational

53608-75-6

Anesthetics

Not Applicable

pancreatin

Interventional clinical trials:

(show all 19)

#	Name	Status	NCT ID	Phase	Drugs
1	OK432 (Picibanil) in the Treatment of Lymphatic Malformations	Active, not recruiting	NCT03427619	Phase 4	OK432
2	Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations	Completed	NCT00010452	Phase 2, Phase 3	picibanil
3	A Study to Evaluate Sildenafil for the Treatment of Lymphatic Malformations	Completed	NCT01290484	Phase 1, Phase 2	Sildenafil
4	Sildenafil for the Treatment of Lymphatic Malformations	Recruiting	NCT02335242	Phase 2	Sildenafil 20 mg tablets
5	Trial of Taselisib in Overgrowth	Recruiting	NCT03290092	Phase 1, Phase 2	Taselisib (GDC0032);Taselisib (GDC0032)
6	Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage Surgery	Recruiting	NCT02437825	Phase 2	octreotide
7	Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies	Active, not recruiting	NCT00975819	Phase 2	sirolimus
8	Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations	Not yet recruiting	NCT03243019	Phase 2	rapamycin
9	Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options.	Completed	NCT00261391	Phase 1	Marimastat
10	Selenium in the Treatment of Complicated Lymphatic Malformations	Terminated	NCT01212965	Phase 1	Selenium
11	Imaging of Lymphatic Anomalies	Completed	NCT02744027	Not Applicable
12	Diagnosis of Hemangiomas and Vascular Malformations	Completed	NCT00577213
13	Lymphatic Anomalies Registry	Recruiting	NCT02399527
14	AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)	Recruiting	NCT02250456
15	Development of a Specific Scale of Life'Quality for Children With Low-flow Vascular Malformations	Recruiting	NCT03440827	Not Applicable
16	Registry for Vascular Anomalies Associated With Coagulopathy	Recruiting	NCT00576888
17	Airway Vascular Lesions	Active, not recruiting	NCT00866827
18	Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders	Enrolling by invitation	NCT00833599		NIRFLI with ICG
19	Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions	Terminated	NCT02494388

Search NIH Clinical Center for Lymphangioma

Cochrane evidence based reviews: lymphangioma

Sources

Genetic Tests for Lymphangioma

Genetic tests related to Lymphangioma:

#	Genetic test	Affiliating Genes
1	Lymphangioma ²⁹

Sources

Anatomical Context for Lymphangioma

MalaCards organs/tissues related to Lymphangioma:

⁴¹

Pancreas, Tongue, Lymph Node, Colon, Spleen, Adrenal Gland, Endothelial

Sources

Publications for Lymphangioma

Articles related to Lymphangioma:

(show top 50) (show all 1055)

#	Title	Authors	Year
1	Genital Warts, Lymphangioma, and Treatment with Imiquimod. ( 29803364 )	Padilla-EspaA+a L....MillA!n-Cayetano J.F.	2018
2	A rare cause of small-bowel bleeding: haemorrhagic small-bowel lymphangioma diagnosed by antegrade double-balloon enteroscopy. ( 29351701 )	Gaeta L....Despott E.J.	2018
3	Ileal Cystic Lymphangioma presenting with Acute Appendicitis. ( 29386763 )	Lui S.A....Mali V.P.	2018
4	Lymphangioma circumscriptum of the tongue: A case with marked hemorrhagic component. ( 29315723 )	Alrashdan M.S....Alorjani M.	2018
5	Lymphangioma Of Tongue. ( 29504356 )	Bajpai M....Kumar M.	2018
6	Isolated splenic lymphangioma presenting as a huge mass causing anemia and abdominal distension in an adult patient: a case report. ( 29656712 )	Efared B....Chbani L.	2018
7	Acquired lymphangioma circumscriptum of the genitals in an individual with chronic hidradenitis suppurativa. ( 29387752 )	Piernick D.M....Daveluy S.	2018
8	Lymphangioma of the Esophagus. ( 29867174 )	Min M....Liu Y.	2018
9	Lymphangioma circumscriptum of the vulva in a patient with Noonan syndrome. ( 29232041 )	Schirra A....Streit E.	2018
10	Endoscopic submucosal dissection of a giant esophageal lymphangioma. ( 29742767 )	Hu L....Wu H.	2018
11	An Unusual Aspirate and Microbiopsy of a Pancreas Cyst Diagnostic for Pancreatic Lymphangioma. ( 29574030 )	Trindade A.J....Rishi A.	2018
12	Lymphangioma on 68Ga-NOTA-Evans Blue PET/MRI. ( 29742595 )	Hou G....Cheng W.	2018
13	Lymphangioma circumscriptum treated with combination of Bleomycin sclerotherapy and Radiofrequency ablation. ( 29979907 )	Khurana A....Malhotra P.	2018
14	Splenic lymphangioma in an adult. ( 29543313 )	Al-Mendalawi M.D....Al-Shaikh S.A.	2018
15	Percutaneous full endoscopic treatment of cystic lymphangioma of cauda equina: a case report. ( 29658356 )	Kim H.S....Oh S.H.	2018
16	Mediastinal lymphangioma in an adult. ( 29397964 )	Nasser M....Cottin V.	2018
17	A young woman with steroid-responsive, IgG4-positive plasma cell-enriched cystic lymphangioma and chylous ascites. ( 29881573 )	Al Zaki A.A....Chen L.Y.C.	2018
18	Sirolimus-induced regression of a large orbital lymphangioma. ( 29405800 )	LagrA"ze W.A....RAPssler J.	2018
19	Lymphangioma Circumscriptum Post Radiotherapy for Penile Cancer Treated with COa88 Laser. ( 29782301 )	Schulz D....Solovan C.	2018
20	Symptomatic lymphangioma of the adrenal gland: a case report. ( 29876049 )	Liechti R....Metzger J.	2018
21	Cystic Lymphangioma: Are Triglycerides Always Measurable? ( 29686910 )	FranAsois S....Mana F.	2018
22	Lymphangioma Circumscriptum in Vulva with Klippel-Trenaunay Syndrome. ( 29451158 )	Liu X.Y....Zhang J.Z.	2018
23	Genital Warts, Lymphangioma, and Treatment with Imiquimod. ( 29803363 )	Monteagudo B....SuA!rez-Amor O.	2018
24	Percutaneous therapy of a mediastinal lymphangioma with fibrin glue: case report with clinical success after 4A years. ( 29361923 )	Zhou S....Du J.	2018
25	A Supernumerary Nipple-Like Clinical Presentation of Lymphangioma Circumscriptum. ( 29796322 )	Taylor D....Silapunt S.	2018
26	Surgery of multiple lymphangioma in small bowel: a rare case report of chronic gastrointestinal bleeding. ( 29333427 )	Lim D.R....Shin E.J.	2018
27	Retroperitoneal cystic lymphangioma in an adult: A case report. ( 29785367 )	Chaker K....Nouira Y.	2018
28	A case of extensive acquired progressive lymphangioma. ( 29633311 )	Larkin S.C....Tollefson M.M.	2018
29	Lymphangioma circumscriptum der Vulva bei einer Patientin mit Noonan-Syndrom. ( 29314699 )	Schirra A....Streit E.	2018
30	Spontaneous rupture of a retroperitoneal lymphangioma: Understanding chylous signal with chemical-shift and TrueFISP MR sequence. ( 29910170 )	CrombAc A....Kind M.	2018
31	Recurring Giant Mediastinal Cystic Lymphangioma. ( 28363031 )	Rali P....Malik K.	2017
32	Vulvar lymphangioma circumscriptum: comparison of primary and acquired forms in a cohort of 57 patients. ( 28758249 )	Simon L....Vignes S.	2017
33	An adult case of lymphangioma of the hepatoduodenal ligament mimicking a hepatic cyst. ( 28050777 )	Kohashi T....Nakahara H.	2017
34	Acquired progressive lymphangioma: Case report with partial response to imiquimod 5% cream. ( 28940760 )	Salman A....Ergun T.	2017
35	Cystic lymphangioma in a 44-year-old woman. ( 28451011 )	Sellami M....Ghorbel A.	2017
36	Cystic lymphangioma of spleen in adults. ( 28122799 )	Duvvada S....Kalluri T.	2017
37	Splenic lymphangioma in an adult. ( 29114705 )	Al-Shaikh S.A....Harb Z.F.	2017
38	Epididymal Cystic Lymphangioma Presenting as Scrotal Swelling in a Post Surgery Case of Carcinoma Rectum- A Case Report. ( 29207807 )	Haroon M....Iqubal K.	2017
39	Cystic lymphangioma of the lesser omentum in a pregnant woman: a case report and review of the literature. ( 28976139 )	Ozdemir O....Unal D.T.	2017
40	Pancreatic Lymphangioma: A Diagnostic and Treatment Dilemma. ( 28738930 )	Nodit L....Hubbard E.	2017
41	A prospective study of the role of intralesional bleomycin in orbital lymphangioma. ( 28300684 )	Raichura N.D....Mukherjee B.	2017
42	A Large Hemispherical Colon Lymphangioma. ( 28050035 )	Katayama Y....Tamano M.	2017
43	Transient Reactive Eruptive Lymphangiectasia Following Partial Vulvectomy for Chronic Acquired Lymphangioma. ( 28859749 )	Wirth P.J....Lin L.	2017
44	Mixed Lymphangioma and Cavernous Hemangioma Within the Ulnar Nerve: A Case Report. ( 28391718 )	Prater M.C....Janz B.A.	2017
45	Small bowel volvulus in an adult with mesenteric lymphangioma and ascariasis. ( 28266164 )	Wei M.Y....Grossberg P.	2017
46	Natural Course of Fetal Axillary Lymphangioma Based on Prenatal Ultrasound Studies. ( 29119576 )	Tongsong T....Charoenratana C.	2017
47	Thoracoscopic resection of a huge mediastinal cystic lymphangioma. ( 29268428 )	Zhou H....Liu L.	2017
48	Imaging findings of axillary cystic lymphangioma in adult. ( 28735807 )	Karabulut D....TunAsbilek N.	2017
49	Incidental finding of (131)I uptake in mesenteric cystic lymphangioma on post-therapy (131)I SPECT/CT imaging. ( 28215398 )	Shao G....Li S.	2017
50	Cystic Lymphangioma of the Colon: Endoscopic Removal beyond the Frontiers of Size. ( 28512390 )	Badipatla K.R....Nayudu S.K.	2017

Sources

Genes for Lymphangioma

Genes related to Lymphangioma (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	FLT4	Fms Related Tyrosine Kinase 4	Protein Coding	31.95	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	19151999 11742043 17584927 (more) 12060670 10697276 11585321 10590384
2	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	27.66	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	19151999 11742043
3	PROX1	Prospero Homeobox 1	Protein Coding	24.82	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : DISEASES inferred (show sections)	12060670 17584927
4	PDPN	Podoplanin	Protein Coding	22.72	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	14559986 10931742 16670463 (more) 11585321 17584927
5	KDR	Kinase Insert Domain Receptor	Protein Coding	21.1	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	IFNA2	Interferon Alpha 2	Protein Coding	20.17	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	19.98	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	ACTC1	Actin, Alpha, Cardiac Muscle 1	Protein Coding	19.27	Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	10922105
9	HBA1	Hemoglobin Subunit Alpha 1	Protein Coding	16.88	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	IFNG	Interferon Gamma	Protein Coding	16.67	GeneCards inferred via : Publications (show sections)
11	SERPINF1	Serpin Family F Member 1	Protein Coding	16.67	GeneCards inferred via : Publications (show sections)

Sources

Variations for Lymphangioma

Sources

Expression for Lymphangioma

Search GEO for disease gene expression data for Lymphangioma.

Sources

Pathways for Lymphangioma

Pathways related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 24)

#	Super pathways	Score	Top Affiliating Genes
1	TGF-Beta Pathway ⁶⁴ Show member pathways JAK-STAT Pathway ⁶⁴ JNK Pathway ⁶⁴ MAPK Family Pathway ⁶⁴ Regulation of eIF4 and p70S6K ⁶⁴ SOCS Pathway ⁶⁴	13.19	FLT4 IFNA2 IFNG KDR VEGFA VEGFC
2	Focal Adhesion ³⁷ ¹ Show member pathways HGF Pathway ⁶⁴ Integrin-mediated Cell Adhesion ¹	12.67	FLT4 KDR VEGFA VEGFC
3	PI3K-Akt signaling pathway ³⁷ Show member pathways Human papillomavirus infection ³⁷	12.63	FLT4 IFNA2 KDR VEGFA VEGFC
4	MAPK signaling pathway ¹ ³⁷	12.54	FLT4 KDR VEGFA VEGFC
5	Ras signaling pathway ³⁷ Show member pathways Rap1 signaling pathway ³⁷	12.48	FLT4 KDR VEGFA VEGFC
6	Pathways in cancer ³⁷	12.44	FLT4 IFNA2 IFNG VEGFA VEGFC
7	VEGF Pathway (Qiagen) ⁶⁴ Show member pathways CCKBR-Gastrin Stimulated Signaling ⁶⁴ Development VEGF-family signaling ²² Neurophilin interactions with VEGF and VEGFR ⁶⁶ VEGF Family Ligands and Receptor Interactions ⁶⁴	12.11	FLT4 KDR VEGFA VEGFC
8	RhoGDI Pathway ⁶⁴ Show member pathways Fc-GammaR-Mediated Phagocytosis in Macrophages ⁶⁴	12.05	FLT4 KDR VEGFA VEGFC
9	VEGF Signaling Pathway ⁶⁷ ⁶¹ Show member pathways Nanoparticle-mediated activation of receptor signaling ¹ TGF-beta Signaling ⁶⁷	12.02	KDR VEGFA VEGFC
10	Tyrosine Kinases / Adaptors ⁴	11.89	FLT4 KDR VEGFC
11	Fluid shear stress and atherosclerosis ³⁷	11.84	IFNG KDR VEGFA
12	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.81	KDR PROX1 VEGFA
13	Immune response IFN gamma signaling pathway ²² Show member pathways IFN-gamma pathway ¹	11.81	FLT4 IFNG KDR VEGFC
14	Signaling events mediated by VEGFR1 and VEGFR2 ¹ Show member pathways VEGFR1 specific signals ¹	11.42	FLT4 KDR VEGFA VEGFC
15	Angiogenesis (CST) ⁴	11.3	FLT4 KDR PDPN PROX1 VEGFC
16	Type II interferon signaling (IFNG) ¹	11.19	IFNA2 IFNG
17	African trypanosomiasis ³⁷	11.16	HBA1 IFNG
18	HIF-2-alpha transcription factor network ¹	11.14	KDR VEGFA
19	Vemurafenib Pathway, Pharmacodynamics ⁶¹	11.06	FLT4 KDR VEGFA
20	Angiogenesis (WikiPathways) ¹	10.96	KDR VEGFA
21	VEGFR3 signaling in lymphatic endothelium ¹	10.94	FLT4 VEGFC
22	Hypertrophy Model ¹	10.86	IFNG VEGFA
23	miR-148a/miR-31/FIH1/HIF1andalpha;-Notch signaling in glioblastoma ¹	10.41	VEGFA VEGFC
24	VEGF ligand-receptor interactions ⁶⁶ Show member pathways VEGF binds to VEGFR leading to receptor dimerization ⁶⁶	10.13	FLT4 KDR VEGFA VEGFC

Sources

GO Terms for Lymphangioma

Cellular components related to Lymphangioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.5	ACTC1 HBA1 IFNA2 IFNG SERPINF1 VEGFA
2	extracellular region	GO:0005576	9.23	FLT4 HBA1 IFNA2 IFNG KDR SERPINF1

Biological processes related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 38)

#	Name	GO ID	Score	Top Affiliating Genes
1	multicellular organism development	GO:0007275	9.95	FLT4 KDR PDPN PROX1 SERPINF1 VEGFA
2	regulation of signaling receptor activity	GO:0010469	9.94	IFNA2 IFNG VEGFA VEGFC
3	negative regulation of apoptotic process	GO:0043066	9.93	ACTC1 FLT4 KDR PDPN VEGFA
4	positive regulation of cell migration	GO:0030335	9.85	KDR PDPN VEGFA
5	angiogenesis	GO:0001525	9.85	FLT4 KDR VEGFA VEGFC
6	positive regulation of cell proliferation	GO:0008284	9.85	FLT4 IFNG KDR PROX1 VEGFA VEGFC
7	regulation of cell shape	GO:0008360	9.83	KDR PDPN VEGFA
8	positive regulation of angiogenesis	GO:0045766	9.82	KDR VEGFA VEGFC
9	kidney development	GO:0001822	9.8	PROX1 SERPINF1 VEGFA
10	lung development	GO:0030324	9.77	PDPN PROX1 VEGFA
11	positive regulation of protein phosphorylation	GO:0001934	9.76	FLT4 IFNG KDR VEGFA
12	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.73	IFNA2 IFNG VEGFA
13	negative regulation of gene expression	GO:0010629	9.72	IFNA2 IFNG KDR SERPINF1 VEGFA
14	vasculogenesis	GO:0001570	9.7	FLT4 KDR VEGFA
15	positive chemotaxis	GO:0050918	9.68	VEGFA VEGFC
16	positive regulation of cell migration involved in sprouting angiogenesis	GO:0090050	9.67	KDR VEGFA
17	positive regulation of focal adhesion assembly	GO:0051894	9.67	KDR VEGFA
18	positive regulation of protein complex assembly	GO:0031334	9.66	IFNG VEGFA
19	positive regulation of protein autophosphorylation	GO:0031954	9.66	VEGFA VEGFC
20	positive regulation of peptidyl-serine phosphorylation of STAT protein	GO:0033141	9.65	IFNA2 IFNG
21	positive regulation of neuroblast proliferation	GO:0002052	9.65	VEGFA VEGFC
22	positive regulation of blood vessel endothelial cell migration	GO:0043536	9.65	KDR VEGFA VEGFC
23	cell migration involved in sprouting angiogenesis	GO:0002042	9.63	KDR VEGFA
24	induction of positive chemotaxis	GO:0050930	9.63	VEGFA VEGFC
25	positive regulation of positive chemotaxis	GO:0050927	9.62	KDR VEGFA
26	lymph vessel development	GO:0001945	9.61	FLT4 PROX1
27	vascular endothelial growth factor signaling pathway	GO:0038084	9.61	FLT4 KDR
28	cellular response to vascular endothelial growth factor stimulus	GO:0035924	9.61	FLT4 KDR VEGFA
29	positive regulation of cellular component movement	GO:0051272	9.59	PDPN VEGFA
30	skeletal muscle thin filament assembly	GO:0030240	9.58	ACTC1 PROX1
31	positive regulation of protein kinase C signaling	GO:0090037	9.58	FLT4 VEGFA
32	positive regulation of mast cell chemotaxis	GO:0060754	9.57	VEGFA VEGFC
33	vascular endothelial growth factor receptor signaling pathway	GO:0048010	9.56	FLT4 KDR VEGFA VEGFC
34	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	GO:0038033	9.51	KDR VEGFA
35	actin-mediated cell contraction	GO:0070252	9.49	ACTC1 PDPN
36	lymphangiogenesis	GO:0001946	9.33	FLT4 PDPN PROX1
37	positive regulation of endothelial cell migration	GO:0010595	9.26	FLT4 KDR PROX1 VEGFA
38	positive regulation of endothelial cell proliferation	GO:0001938	9.02	FLT4 KDR PROX1 VEGFA VEGFC

Molecular functions related to Lymphangioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chemoattractant activity	GO:0042056	9.16	VEGFA VEGFC
2	cytokine activity	GO:0005125	9.13	IFNA2 IFNG VEGFA
3	vascular endothelial growth factor-activated receptor activity	GO:0005021	8.62	FLT4 KDR

Sources

Sources for Lymphangioma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia