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MCID: LYM024
MIFTS: 49
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Lymphatic System Disease
Categories:
Immune diseases
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MalaCards integrated aliases for Lymphatic System Disease:
Classifications: |
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MedlinePlus
:
43
The lymphatic system is a network of tissues and organs. It is made up of
Lymph - a fluid that contains white blood cells that defend against germs
Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels.
Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection.
Your bone marrow and thymus produce the cells in lymph. They are part of the system, too.
The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.
MalaCards based summary : Lymphatic System Disease, also known as lymphatic diseases, is related to hemophagocytic lymphohistiocytosis and lymphedema, and has symptoms including edema, axillary lymph node pain and axillary lymph node tenderness. An important gene associated with Lymphatic System Disease is UNC13D (Unc-13 Homolog D), and among its related pathways/superpathways are Deregulation of Rab and Rab Effector Genes in Bladder Cancer and VEGF binds to VEGFR leading to receptor dimerization. The drug Sirolimus has been mentioned in the context of this disorder. Affiliated tissues include lymph node, b cells and bone, and related phenotypes are hematopoietic system and homeostasis/metabolism Disease Ontology : 12 An immune system disease that is located in the lymphatic system. Wikipedia : 76 Lymphatic disease is a class of disorders which directly affect the components of the lymphatic... more... |
UMLS symptoms related to Lymphatic System Disease:edema, axillary lymph node pain, axillary lymph node tenderness MGI Mouse Phenotypes related to Lymphatic System Disease:46
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Drugs for Lymphatic System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
Interventional clinical trials:
Cochrane evidence based reviews: lymphatic diseases |
Genetic tests related to Lymphatic System Disease:
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MalaCards organs/tissues related to Lymphatic System Disease:41
Lymph Node,
B Cells,
Bone,
Bone Marrow,
T Cells,
Spleen,
Thymus
The Foundational Model of Anatomy Ontology organs/tissues related to Lymphatic System Disease:19
The Lymphatic System
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Articles related to Lymphatic System Disease:
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Genes related to Lymphatic System Disease (0 elite genes):(show all 28) - Elite gene
- Cancer Census gene in COSMIC
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Search
GEO
for disease gene expression data for Lymphatic System Disease.
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Cellular components related to Lymphatic System Disease according to GeneCards Suite gene sharing:
Biological processes related to Lymphatic System Disease according to GeneCards Suite gene sharing:
Molecular functions related to Lymphatic System Disease according to GeneCards Suite gene sharing:
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