MCID: LYM040
MIFTS: 57

Lymphoblastic Lymphoma

Categories: Blood diseases, Cancer diseases, Immune diseases, Rare diseases

Aliases & Classifications for Lymphoblastic Lymphoma

MalaCards integrated aliases for Lymphoblastic Lymphoma:

Name: Lymphoblastic Lymphoma 38 12 76 53 15
Precursor Cell Lymphoblastic Leukemia Lymphoma 73
Precursor Cell Lymphoblastic Lymphoma 73
Lymphoma, Lymphoblastic 53
Lymphoma Lymphoblastic 55

Classifications:



External Ids:

Disease Ontology 12 DOID:0080147
ICD10 33 C83.5

Summaries for Lymphoblastic Lymphoma

Disease Ontology : 12 A lymphoma that has material basis in immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage and located in primarily lymph nodes or located in extranodal sites.

MalaCards based summary : Lymphoblastic Lymphoma, also known as precursor cell lymphoblastic leukemia lymphoma, is related to acute t cell leukemia and leukemia, acute lymphoblastic. An important gene associated with Lymphoblastic Lymphoma is ZMYM2 (Zinc Finger MYM-Type Containing 2), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional misregulation in cancer. The drugs Arranon and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone and bone marrow, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Wikipedia : 76 Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the... more...

Related Diseases for Lymphoblastic Lymphoma

Diseases related to Lymphoblastic Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 acute t cell leukemia 32.1 NOTCH1 TAL1 TRB
2 leukemia, acute lymphoblastic 30.9 DNTT KMT2A MME
3 lymphocytic leukemia 30.3 CD5 DNTT KMT2A MME NOTCH1 TAL1
4 leukemia, acute lymphoblastic 3 30.1 CDKN2B DNTT KMT2A MME MPO
5 acute lymphocytic leukemia 30.0 CDKN2B MME NOTCH1 TAL1
6 acute leukemia 29.8 DNTT KMT2A MPO TAL1
7 8p11 myeloproliferative syndrome 29.8 FGFR1 ZMYM2
8 myeloid sarcoma 29.7 DNTT KMT2A MPO PTPRC
9 lymphosarcoma 29.7 BCL6 CD5 PTPRC
10 thymoma 29.7 CD5 DNTT PTPRC TRB
11 ewing's family of tumors 29.7 CDKN2B FLI1
12 peripheral t-cell lymphoma 29.6 BCL6 CD5 MME
13 diffuse large b-cell lymphoma 29.6 BCL6 CD5 MME
14 burkitt lymphoma 29.6 BCL6 DNTT MME
15 b-cell lymphomas 29.6 BCL6 CD5 MME
16 acute biphenotypic leukemia 29.6 DNTT KMT2A MPO
17 dendritic cell tumor 29.5 DNTT MPO PTPRC
18 pediatric lymphoma 29.5 DNTT MME
19 lymphoma, hodgkin, classic 29.5 BCL6 CD5 MME PTPRC
20 leukemia, chronic myeloid 29.5 CDKN2B DNTT FGFR1 KMT2A MPO
21 mantle cell lymphoma 29.2 BCL6 CD5 MME PTPRC
22 leukemia, chronic lymphocytic 29.2 BCL6 CD5 DNTT NOTCH1 PTPRC
23 leukemia, acute myeloid 29.2 CDKN2B DNTT KMT2A MME MPO PTPRC
24 lymphoma, non-hodgkin, familial 29.0 BCL6 CD5 CDKN2B DNTT MME NOTCH1
25 precursor t-cell acute lymphoblastic leukemia 28.8 CDKN2B DNTT KMT2A MPO NOTCH1 TAL1
26 t-cell childhood lymphoblastic lymphoma 12.5
27 precursor t-lymphoblastic lymphoma/leukemia 12.4
28 precursor b lymphoblastic lymphoma/leukemia 12.2
29 precursor lymphoblastic lymphoma/leukemia 12.2
30 childhood precursor t-lymphoblastic lymphoma/leukemia 12.1
31 precursor t-lymphoblastic lymphoma/leukemia refractory 12.1
32 chromosome 8p11 myeloproliferative syndrome 11.2
33 lymphoma 11.1
34 leukemia 10.6
35 myasthenic syndrome, congenital, 6, presynaptic 10.2 FGFR1 ZMYM2
36 photokeratitis 10.2 DNTT PTPRC
37 chromosomal triplication 10.2 BCL6 KMT2A
38 immunodeficiency 18 10.2 PTPRC TAL1
39 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.2 BCL6 PTPRC
40 sarcoma 10.1
41 ovarian lymphoma 10.1 MME PTPRC
42 hematopoietic stem cell transplantation 10.1
43 t-cell/histiocyte rich large b cell lymphoma 10.1 BCL6 MME
44 breast lymphoma 10.1 BCL6 CD5
45 extraskeletal ewing sarcoma 10.1 FLI1 PTPRC
46 myeloproliferative neoplasm 10.1
47 composite lymphoma 10.1 BCL6 CD5
48 erythroleukemia, familial 10.1 FLI1 TAL1
49 tracheal lymphoma 10.1 CD5 MME
50 central nervous system hematologic cancer 10.1 BCL6 MME

Graphical network of the top 20 diseases related to Lymphoblastic Lymphoma:



Diseases related to Lymphoblastic Lymphoma

Symptoms & Phenotypes for Lymphoblastic Lymphoma

GenomeRNAi Phenotypes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 BCL6 CD5 KMT2A NOTCH1 PTPRC ZMYM2

MGI Mouse Phenotypes related to Lymphoblastic Lymphoma:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.22 BCL6 CD5 CDKN2B DNTT FGFR1 FLI1
2 immune system MP:0005387 10.21 BCL6 CD5 CDKN2B DNTT FGFR1 FLI1
3 homeostasis/metabolism MP:0005376 10.16 BCL6 CDKN2B DNTT FGFR1 KMT2A MME
4 cardiovascular system MP:0005385 10.1 BCL6 DNTT FGFR1 FLI1 KMT2A MPO
5 mortality/aging MP:0010768 10.02 BCL6 CDKN2B FGFR1 FLI1 KMT2A MPO
6 integument MP:0010771 9.95 CD5 CDKN2B FGFR1 KMT2A MME NOTCH1
7 liver/biliary system MP:0005370 9.85 BCL6 FLI1 KMT2A MME NOTCH1 PTPRC
8 muscle MP:0005369 9.73 BCL6 FGFR1 FLI1 KMT2A MPO NOTCH1
9 no phenotypic analysis MP:0003012 9.63 BCL6 CD5 CDKN2B FGFR1 KMT2A PTPRC
10 normal MP:0002873 9.5 BCL6 CD5 DNTT FGFR1 KMT2A NOTCH1
11 renal/urinary system MP:0005367 9.1 CDKN2B FGFR1 KMT2A NOTCH1 PTPRC TAL1

Drugs & Therapeutics for Lymphoblastic Lymphoma

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Arranon 18 49 NELARABINE GlaxoSmithKline October 2005

Drugs for Lymphoblastic Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 493)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 302-25-0
2
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
3
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 57-22-7, 2068-78-2 5978
4
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-05-2, 1959-05-2 126941
5
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
6
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2921-57-5
7
Vindesine Approved, Investigational Phase 4,Phase 3,Phase 2 59917-39-4, 53643-48-4 40839
8
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 6055-19-2, 50-18-0 2907
9
Thioguanine Approved Phase 4,Phase 3,Phase 2,Phase 1 154-42-7 2723601
10
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 33419-42-0 36462
11
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 147-94-4 6253
12
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 23214-92-8 31703
13
Cladribine Approved, Investigational Phase 4,Phase 2,Phase 1 4291-63-8 20279
14
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 20830-81-3 30323
15
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1177-87-3
16
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
17
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-05-9 6006 143
18
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 174722-31-7 10201696
19
Ifosfamide Approved Phase 4,Phase 2,Phase 3,Phase 1 3778-73-2 3690
20
Lenograstim Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 135968-09-1
21
Busulfan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 55-98-1 2478
22
Thiotepa Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 52-24-4 5453
23
Azacitidine Approved, Investigational Phase 4,Phase 2,Phase 1 320-67-2 9444
24
Morphine Approved, Investigational Phase 4,Phase 3,Not Applicable 57-27-2 5288826
25
Decitabine Approved, Investigational Phase 4,Phase 2,Phase 1 2353-33-5 451668
26
Epirubicin Approved Phase 4,Phase 2 56420-45-2 41867
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-30-3 6037
28
Prednisolone hemisuccinate Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2920-86-7
29
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 31703
30 6-Mercaptopurine Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Prednisolone acetate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
33 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
34 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
36 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37
asparaginase Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Etoposide phosphate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
40 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Vitamin B Complex Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
42 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
43 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
45 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
46 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
50 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 655)
# Name Status NCT ID Phase Drugs
1 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4 Dexamethasone/Prednisolone;Cyclophosphamide;Vincristine;Daunorubicin;Asparaginase;G-CSF;Mercaptopurine;Cytarabine;Methotrexate;VP16;Vindesine;Adriamycin;Thioguanine;HDARAC;Cladribine
2 Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults Completed NCT00199082 Phase 4 Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone/Prednisolone;VP16;Ifosfamide;Methotrexate;G-CSF;Rituximab;Vincristine/Vindesine
3 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4 cyclophosphamide;thiotepa
4 A Clinical Trial of Decitabine in Relapsed or Refractory T-lymphoblastic Lymphoma Recruiting NCT03558412 Phase 4 Decitabine
5 ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors Recruiting NCT02938741 Phase 4 Anti-human Thymoglobulin;Placebo
6 Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma Unknown status NCT00004228 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;prednisone;thioguanine;vincristine sulfate
7 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003650 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisone;vincristine sulfate
8 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3 ketamine hydrochloride
9 Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia Unknown status NCT00445497 Phase 3 amoxicillin-clavulanate potassium;ciprofloxacin
10 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003423 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;mercaptopurine;methotrexate;prednisolone;thioguanine;vincristine sulfate
11 Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma Unknown status NCT00003728 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;leucovorin calcium;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisolone;therapeutic hydrocortisone;thioguanine;vincristine sulfate;vindesine
12 Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia Unknown status NCT00020865 Phase 3 cefepime hydrochloride;levofloxacin
13 Monoclonal Antibodies in Detecting Residual Disease in Patients Who Have Been Treated for Non-Hodgkin's Lymphoma Unknown status NCT00003338 Phase 2, Phase 3
14 Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma Unknown status NCT00003337 Phase 3
15 Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome Unknown status NCT00002989 Phase 3 busulfan;cyclophosphamide;idarubicin;melphalan
16 Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma Unknown status NCT00003815 Phase 3 carmustine;cyclophosphamide;cytarabine;doxorubicin hydrochloride;etoposide;melphalan;prednisolone;vincristine sulfate
17 Combination Chemotherapy Followed By Radiation Therapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma Unknown status NCT00053768 Phase 3 EPOCH regimen;cyclophosphamide;doxorubicin hydrochloride;etoposide;prednisone;vincristine sulfate
18 Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma Unknown status NCT00052936 Phase 3 CHOP regimen;cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
19 Interferon Alfa-2b Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma Unknown status NCT00003924 Phase 3
20 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Completed NCT00408005 Phase 3 Asparaginase;Cyclophosphamide;Cytarabine;Daunorubicin Hydrochloride;Dexamethasone;Doxorubicin Hydrochloride;Leucovorin Calcium;Mercaptopurine;Methotrexate;Nelarabine;Pegaspargase;Prednisone;Thioguanine;Vincristine Sulfate
21 Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma Completed NCT00003187 Phase 2, Phase 3 cyclophosphamide;cyclosporine;cytarabine;methotrexate;methylprednisolone
22 A Study of Actonel for the Prevention of Bone Loss Completed NCT00452439 Phase 3 Actonel (Risedronate)
23 Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma Completed NCT00002766 Phase 3 carmustine;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;mercaptopurine;methotrexate;mitoxantrone hydrochloride;pegaspargase;prednisone;vincristine sulfate
24 Study of Treatment High Risk and/or Low Risk Acute Lymphoblastic leukémia(ALL) Adults Stage III Completed NCT00483132 Phase 3 interferon alpha 2a
25 Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications Completed NCT00799461 Phase 3
26 Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma Completed NCT01230983 Phase 3 asparaginase;cytarabine;dexrazoxane hydrochloride;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;prednisone;therapeutic hydrocortisone;vincristine sulfate
27 Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia Completed NCT00002700 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;mitoxantrone hydrochloride;prednisolone;prednisone;therapeutic hydrocortisone;vincristine sulfate
28 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
29 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3 American ginseng
30 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
31 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3 sodium ferric gluconate complex in sucrose
32 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
33 Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count Completed NCT00003805 Phase 3 piperacillin sodium;piperacillin-tazobactam;tazobactam sodium;vancomycin
34 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
35 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
36 Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer Completed NCT00265837 Phase 3
37 St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer Completed NCT00005805 Phase 3
38 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3 Fragmin
39 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
40 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
41 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
42 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
43 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
44 Combination Chemotherapy in Treating Older Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma Completed NCT00002576 Phase 3 cyclophosphamide;doxorubicin hydrochloride;mitoxantrone hydrochloride;prednisolone;vincristine sulfate
45 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
46 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
47 Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Completed NCT00369564 Phase 3 glutamic acid
48 Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases Completed NCT00438958 Phase 3
49 Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer Completed NCT00053053 Phase 3
50 Treatment for Chronic Pain in Patients With Advanced Cancer Completed NCT00003687 Phase 3 dextromethorphan hydrobromide;morphine sulfate

Search NIH Clinical Center for Lymphoblastic Lymphoma

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Lymphoblastic Lymphoma cell therapies at LifeMap Discovery.

Genetic Tests for Lymphoblastic Lymphoma

Anatomical Context for Lymphoblastic Lymphoma

MalaCards organs/tissues related to Lymphoblastic Lymphoma:

41
T Cells, Bone, Bone Marrow, B Cells, Lymph Node, B Lymphoblasts, Myeloid

The Foundational Model of Anatomy Ontology organs/tissues related to Lymphoblastic Lymphoma:

19
Primarily Lymph Nodes Or

Publications for Lymphoblastic Lymphoma

Articles related to Lymphoblastic Lymphoma:

(show top 50) (show all 672)
# Title Authors Year
1
Transformation of T-Cell Acute Lymphoblastic Lymphoma to Peripheral T-Cell Lymphoma: A Report of Two Cases. ( 29682368 )
2018
2
Lymphoblastic Lymphoma Involving Multiple Vertebrae. ( 28962960 )
2018
3
Pediatric Patient With T-Cell Lymphoblastic Lymphoma and Acute Vision Loss. ( 29121170 )
2018
4
Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group. ( 29090524 )
2018
5
Terminal deoxynucleotidyl transferase (TdT)-negative T-cell lymphoblastic lymphoma with loss of the T-cell lineage-specific marker CD3 at relapse: a rare entity with an aggressive outcome. ( 29884716 )
2018
6
Patients over 40 years old with precursor T-cell lymphoblastic lymphoma have different prognostic factors comparing to the youngers. ( 29348421 )
2018
7
Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma. ( 29047158 )
2018
8
Myositis in bilateral calves mimicking lymphoma on interim PET/CT in a patient with T-lymphoblastic lymphoma. ( 29590432 )
2018
9
Allogeneic hematopoietic stem cell transplantation should be in preference to conventional chemotherapy as post-remission treatment for adults with lymphoblastic lymphoma. ( 29712994 )
2018
10
Acute lymphoblastic leukemia and lymphoblastic lymphoma in adolescents and young adults. ( 29418064 )
2018
11
A case report of B lymphoblastic lymphoma with brain metastases: Clinical and pathological significance of head trauma misdiagnosis. ( 29768334 )
2018
12
Successful treatment of pulmonary invasive fungal infection by <i>Penicillium</i> non<i>-marneffei</i> in lymphoblastic lymphoma: case report and literature review. ( 29881585 )
2018
13
Precursor T-Lymphoblastic Lymphoma Associated with t(8;9)(p11.2;q33): A Case Report and Review of the Literature. ( 29614500 )
2018
14
T Cell-Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation for Treatment of T-Lymphoblastic Lymphoma. ( 29930241 )
2018
15
Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial-mesenchymal transition via regulating the PI3K/AKT/mTOR pathway. ( 29483777 )
2018
16
Diagnostic challenges in T-lymphoblastic lymphoma, early T-cell precursor acute lymphoblastic leukemia or mixed phenotype acute leukemia: A case report. ( 30313079 )
2018
17
Coexistence of T-cell lymphoblastic lymphoma and acute myeloid leukemia mimicking acute lymphocytic leukemia. ( 30004087 )
2018
18
T-Cell Acute Lymphoblastic Lymphoma Presenting as Dissecting Cellulitis and Cavernous Sinus Syndrome. ( 30418330 )
2018
19
Outcome of adult T-lymphoblastic lymphoma depends on ALL-type chemotherapy, prognostic factors, and performance of allogeneic hematopoietic stem cell transplantation. ( 29995776 )
2018
20
Expression and significance of CD47, PD1 and PDL1 in T-cell acute lymphoblastic lymphoma/leukemia. ( 30466764 )
2018
21
Philadelphia chromosome-positive lymphoblastic lymphoma-Is it rare or underdiagnosed? ( 29913129 )
2018
22
Treatment of young adults with Philadelphia-negative acute lymphoblastic leukemia and lymphoblastic lymphoma: Hyper-CVAD vs. pediatric-inspired regimens. ( 30058716 )
2018
23
A Young Manwith a Mass: Non-Early Precursor T-Cell Lymphoblastic Lymphoma. ( 30138599 )
2018
24
Phase II Clinical Trial for Newly Diagnosed Children and Adolescents with Localized Lymphoblastic Lymphoma (Japanese Leukemia/Lymphoma Study Group Trial LLB-NHL03) : Study Protocol for Nationwide Multicenter Trial. ( 30140093 )
2018
25
Lymphoblastic Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group (ILROG). ( 30238900 )
2018
26
B-lymphoblastic lymphoma with the TCF3-PBX1 fusion gene. ( 30262566 )
2018
27
T-lymphoblastic lymphoma after previous thymoma: how NGS helps establishing the diagnosis and procures new insights. ( 30301393 )
2018
28
T-cell lymphoblastic lymphoma involving the ocular adnexa: report of two cases and review of the current literature. ( 30396307 )
2018
29
A Rare Presentation of Precursor B-cell Lymphoblastic Lymphoma in a Child. ( 30410844 )
2018
30
B-cell lymphoblastic lymphoma of the nictitating membrane as the first presenting sign in a 2-year-old Springer Spaniel. ( 30455930 )
2018
31
MEG3 affects the progression and chemoresistance of T-cell lymphoblastic lymphoma by suppressing epithelial-mesenchymal transition via the PI3K/mTOR pathway. ( 30556337 )
2018
32
Case Report: A Cryptosporidium infection in a patient with relapsed T-lymphoblastic lymphoma undergoing allogeneic stem cell transplantation. ( 29140544 )
2017
33
Indolent T-lymphoblastic proliferation concomitant with acinic cell carcinoma mimicking T-lymphoblastic lymphoma: case report and literature review. ( 29143359 )
2017
34
Myeloid Neoplasia and Lymphoblastic Lymphoma with Eosinophilia After RAI: A Case Report. ( 28958974 )
2017
35
Clinical impact of miR-223 expression in pediatric T-Cell lymphoblastic lymphoma. ( 29296210 )
2017
36
Immunophenotypic analysis of adult patients with T-cell lymphoblastic lymphoma treated with hyper-CVAD. ( 28778131 )
2017
37
Clinical characteristics and outcomes of previously untreated patients with adult onset T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma with hyper-CVAD based regimens. ( 28646517 )
2017
38
Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma. ( 28827401 )
2017
39
A CD34-negative <i>MYC</i>-rearranged B-lymphoblastic lymphoma aberrantly expresses CD3 and CD5. ( 28280048 )
2017
40
Image Gallery: Primary cutaneous precursor B-lymphoblastic lymphoma in an infant. ( 29313927 )
2017
41
The inhibitory effect of MEG3/miR-214/AIFM2 axis on the growth of T-cell lymphoblastic lymphoma. ( 28534937 )
2017
42
Lymphoblastic lymphoma of the palate. ( 28966460 )
2017
43
B-cell lymphoblastic lymphoma presenting as solitary temporal mass with amplification of AML1/RUNX1: case report. ( 28933515 )
2017
44
Successful Treatment of Mediastinal I^I' T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation. ( 29200146 )
2017
45
Prognostic Factors and Outcomes of Adult Lymphoblastic Lymphoma in the United States. ( 28647403 )
2017
46
Philadelphia chromosome-positive B-lymphoblastic lymphoma involving the genitourinary system and bone at initial diagnosis and relapse. ( 28935645 )
2017
47
JSH guideline for tumors of hematopoietic and lymphoid tissues-leukemia: 3. Acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL). ( 29067593 )
2017
48
Mathematical model of T-cell lymphoblastic lymphoma: disease, treatment, cure or relapse of a virtual cohort of patients. ( 28082512 )
2017
49
Safety and efficacy of nelarabine in children and young adults with relapsed or refractory T-lineage acute lymphoblastic leukaemia or T-lineage lymphoblastic lymphoma: results of a phase 4 study. ( 28771663 )
2017
50
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017

Variations for Lymphoblastic Lymphoma

Expression for Lymphoblastic Lymphoma

Search GEO for disease gene expression data for Lymphoblastic Lymphoma.

Pathways for Lymphoblastic Lymphoma

GO Terms for Lymphoblastic Lymphoma

Biological processes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of hematopoietic stem cell differentiation GO:1902036 9.4 KMT2A TAL1
2 cellular response to extracellular stimulus GO:0031668 9.37 CDKN2B PTPRC
3 embryonic hemopoiesis GO:0035162 9.32 KMT2A TAL1
4 megakaryocyte development GO:0035855 9.26 FLI1 TAL1
5 generation of neurons GO:0048699 9.16 FGFR1 TAL1
6 megakaryocyte differentiation GO:0030219 8.96 CDKN2B TAL1
7 regulation of cell proliferation GO:0042127 8.92 BCL6 FGFR1 NOTCH1 TAL1

Molecular functions related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity GO:0003700 9.65 BCL6 FLI1 KMT2A NOTCH1 TAL1
2 heparin binding GO:0008201 9.33 FGFR1 MPO PTPRC
3 RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 9.13 FLI1 KMT2A TAL1
4 chromatin binding GO:0003682 9.02 BCL6 FLI1 MPO NOTCH1 TAL1

Sources for Lymphoblastic Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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