Lymphoblastic Lymphoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: LYM040 MIFTS: 57	Lymphoblastic Lymphoma Categories: Blood diseases, Cancer diseases, Immune diseases, Rare diseases
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Aliases & Classifications for Lymphoblastic Lymphoma

MalaCards integrated aliases for Lymphoblastic Lymphoma:

Name: Lymphoblastic Lymphoma ³⁹ ¹² ⁷⁷ ⁵⁴ ¹⁵

Precursor Cell Lymphoblastic Leukemia Lymphoma ⁷⁴

Precursor Cell Lymphoblastic Lymphoma ⁷⁴

Lymphoma, Lymphoblastic ⁵⁴

Lymphoma Lymphoblastic ⁵⁶

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Blood diseases Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Neoplasms

Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

Non-follicular lymphoma

Lymphoblastic (diffuse) lymphoma

External Ids:

Disease Ontology ¹² DOID:0080147

ICD10 ³⁴ C83.5

UMLS ⁷⁴ C0079748 C1961102

Sources

Summaries for Lymphoblastic Lymphoma

Disease Ontology : ¹² A lymphoma that has material basis in immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage and located in primarily lymph nodes or located in extranodal sites.

MalaCards based summary : Lymphoblastic Lymphoma, also known as precursor cell lymphoblastic leukemia lymphoma, is related to acute t cell leukemia and leukemia, acute lymphoblastic. An important gene associated with Lymphoblastic Lymphoma is ZMYM2 (Zinc Finger MYM-Type Containing 2), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional misregulation in cancer. The drugs Arranon and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and bone, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Wikipedia : ⁷⁷ Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the... more...

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Related Diseases for Lymphoblastic Lymphoma

Diseases related to Lymphoblastic Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 173)

#	Related Disease	Score	Top Affiliating Genes
1	acute t cell leukemia	31.9	CD7 NOTCH1 TAL1 TRB
2	leukemia, acute lymphoblastic	31.1	DNTT KMT2A MME
3	acute lymphocytic leukemia	30.4	CDKN2B MME NOTCH1 TAL1
4	leukemia, acute lymphoblastic 3	30.1	CDKN2B DNTT KMT2A MME MPO
5	lymphocytic leukemia	29.9	CD5 DNTT KMT2A MME NOTCH1 TAL1
6	ewing's family of tumors	29.8	CDKN2B FLI1
7	myeloid sarcoma	29.8	DNTT KMT2A MPO PTPRC
8	8p11 myeloproliferative syndrome	29.8	FGFR1 ZMYM2
9	bone marrow cancer	29.7	FGFR1 KMT2A MPO ZMYM2
10	acute biphenotypic leukemia	29.7	DNTT KMT2A MPO
11	dendritic cell tumor	29.7	DNTT MPO PTPRC
12	thymoma	29.5	CD5 DNTT PTPRC TRB
13	leukemia, chronic myeloid	29.5	CDKN2B DNTT FGFR1 KMT2A MPO
14	acute leukemia	29.5	CD7 DNTT KMT2A MPO TAL1
15	peripheral t-cell lymphoma	29.4	BCL6 CD5 MME
16	diffuse large b-cell lymphoma	29.4	BCL6 CD5 MME
17	lymphosarcoma	29.3	BCL6 CD5 PTPRC
18	lymphoma, hodgkin, classic	29.2	BCL6 CD5 MME PTPRC
19	mantle cell lymphoma	28.9	BCL6 CD5 MME PTPRC
20	leukemia, acute myeloid	28.5	CD7 CDKN2B DNTT KMT2A MME MPO
21	precursor t-cell acute lymphoblastic leukemia	28.5	CD7 CDKN2B DNTT KMT2A MPO NOTCH1
22	lymphoma, non-hodgkin, familial	28.1	BCL6 CD5 CD7 CDKN2B DNTT MME
23	t-cell childhood lymphoblastic lymphoma	12.5
24	precursor t-lymphoblastic lymphoma/leukemia	12.4
25	precursor b lymphoblastic lymphoma/leukemia	12.3
26	precursor lymphoblastic lymphoma/leukemia	12.3
27	childhood precursor t-lymphoblastic lymphoma/leukemia	12.2
28	precursor t-lymphoblastic lymphoma/leukemia refractory	12.2
29	chromosome 8p11 myeloproliferative syndrome	11.3
30	lymphoma	11.1
31	leukemia	10.7
32	myasthenic syndrome, congenital, 6, presynaptic	10.3	FGFR1 ZMYM2
33	photokeratitis	10.3	DNTT PTPRC
34	chromosomal triplication	10.3	BCL6 KMT2A
35	hodgkin's lymphoma, lymphocytic-histiocytic predominance	10.3	BCL6 PTPRC
36	immunodeficiency 18	10.3	PTPRC TAL1
37	ovarian lymphoma	10.2	MME PTPRC
38	t-cell/histiocyte rich large b cell lymphoma	10.2	BCL6 MME
39	chronic monocytic leukemia	10.2	MPO PTPRC
40	extraskeletal ewing sarcoma	10.2	FLI1 PTPRC
41	erythroleukemia, familial	10.2	FLI1 TAL1
42	sarcoma	10.2
43	central nervous system hematologic cancer	10.2	BCL6 MME
44	plasmablastic lymphoma	10.1	BCL6 NOTCH1 PTPRC
45	burkitt lymphoma	10.1
46	thymoma, familial	10.1
47	hematopoietic stem cell transplantation	10.1
48	myeloproliferative neoplasm	10.1
49	hypereosinophilic syndrome	10.1
50	acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	10.1	DNTT KMT2A MPO

Graphical network of the top 20 diseases related to Lymphoblastic Lymphoma:

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Symptoms & Phenotypes for Lymphoblastic Lymphoma

GenomeRNAi Phenotypes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

²⁷

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.17	BCL6 CD5 CD7 KMT2A NOTCH1 PTPRC

MGI Mouse Phenotypes related to Lymphoblastic Lymphoma:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	10.21	BCL6 CD5 CD7 CDKN2B DNTT FGFR1
2	immune system	MP:0005387	10.18	BCL6 CD5 CD7 CDKN2B DNTT FGFR1
3	homeostasis/metabolism	MP:0005376	10.1	BCL6 CDKN2B DNTT FGFR1 KMT2A MME
4	cardiovascular system	MP:0005385	10	BCL6 FGFR1 FLI1 KMT2A MPO NOTCH1
5	integument	MP:0010771	9.87	CD5 CDKN2B FGFR1 KMT2A MME NOTCH1
6	liver/biliary system	MP:0005370	9.73	BCL6 FLI1 KMT2A MME NOTCH1 PTPRC
7	no phenotypic analysis	MP:0003012	9.63	BCL6 CD5 CDKN2B FGFR1 KMT2A PTPRC
8	normal	MP:0002873	9.5	BCL6 CD5 DNTT FGFR1 KMT2A NOTCH1
9	renal/urinary system	MP:0005367	9.1	CDKN2B FGFR1 KMT2A NOTCH1 PTPRC TAL1

Sources

Drugs & Therapeutics for Lymphoblastic Lymphoma

FDA approved drugs:

#	Drug Name	Active Ingredient(s) ¹⁹	Company	Approval Date
1	Arranon ¹⁹ ⁵⁰	NELARABINE	GlaxoSmithKline	October 2005
FDA Label: Arranon Disease/s that Drug Treats:Lymphoblastic Leukemia Indications and Usage: ¹⁹ ARRANON is a nucleoside metabolic inhibitor indicated for the treatment ofpatients with T-cell acute lymphoblastic leukemia and T-cell lymphoblasticlymphoma whose disease has not responded to or has relapsed followingtreatment with at least two chemotherapy regimens. This use is based on theinduction of complete responses. Randomized trials demonstrating increasedsurvival or other clinical benefit have not been conducted. (1) DrugBank Targets: ¹⁶ DNA Mechanism of Action: ¹⁹ Target: DNA synthesis Action: disruptor --> apoptosis FDA: Nelarabine is a pro-drug of the deoxyguanosine analogue 9-Î²-D-arabinofuranosylguanine266 (ara-G), a nucleoside metabolic inhibitor. Nelarabine is demethylated by adenosine deaminase267 (ADA) to ara-G, mono-phosphorylated by deoxyguanosine kinase and deoxycytidine kinase, and268 subsequently converted to the active 5â-triphosphate, ara-GTP. Accumulation of ara-GTP in269 leukemic blasts allows for incorporation into deoxyribonucleic acid (DNA), leading to inhibition270 of DNA synthesis and cell death. Other mechanisms may contribute to the cytotoxic and271 systemic toxicity of nelarabine.

Drugs for Lymphoblastic Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 692)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Methotrexate

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

1959-05-2, 59-05-2

126941

Prednisone

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

53-03-2

5865

Dasatinib

Approved, Investigational

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

302962-49-8

3062316

Dexamethasone acetate

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

1177-87-3

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

50-02-2

5743

leucovorin

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

58-05-9

143 6006

Idarubicin

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

58957-92-9

42890

Daunorubicin

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

20830-81-3

30323

Cytarabine

Approved, Experimental, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

147-94-4, 65-46-3

6253

Vincristine

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

2068-78-2, 57-22-7

5978

Mercaptopurine

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

50-44-2

667490

Sargramostim

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

123774-72-1, 83869-56-1

rituximab

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable

174722-31-7

10201696

Cyclophosphamide

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

50-18-0, 6055-19-2

2907

Lenograstim

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

135968-09-1

Methylprednisolone

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

83-43-2

6741

Methylprednisolone hemisuccinate

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

2921-57-5

Prednisolone phosphate

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

302-25-0

Prednisolone

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

50-24-8

5755

Pegaspargase

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

130167-69-0

Doxorubicin

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

23214-92-8

31703

Cladribine

Approved, Investigational

Phase 4,Phase 2,Phase 1,Not Applicable

4291-63-8

20279

Etoposide

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

33419-42-0

36462

Thioguanine

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

154-42-7

2723601

Fludarabine

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

75607-67-9, 21679-14-1

30751

Vindesine

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

53643-48-4, 59917-39-4

40839

Teniposide

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

29767-20-2

34698

Ifosfamide

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable

3778-73-2

3690

Thiotepa

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

52-24-4

5453

Mitoxantrone

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

65271-80-9

4212

Hydrocortisone

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

50-23-7

5754

Hydrocortisone acetate

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

50-03-3

Miconazole

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

22916-47-8

4189

Epirubicin

Approved

Phase 4,Phase 3,Phase 2

56420-45-2

41867

Busulfan

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

55-98-1

2478

Micafungin

Approved, Investigational

Phase 4,Phase 2

235114-32-6

477468 3081921

Posaconazole

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

171228-49-2

147912

Dopamine

Approved

Phase 4,Not Applicable

62-31-7, 51-61-6

681

Methylphenidate

Approved, Investigational

Phase 4,Not Applicable

113-45-1

4158

Oprelvekin

Approved, Investigational

Phase 4,Phase 2

145941-26-0

Morphine

Approved, Investigational

Phase 4,Phase 3,Not Applicable

57-27-2

5288826

Decitabine

Approved, Investigational

Phase 4,Phase 1,Phase 2,Not Applicable

2353-33-5

451668

Azacitidine

Approved, Investigational

Phase 4,Phase 1,Phase 2,Not Applicable

320-67-2

9444

inotuzumab ozogamicin

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1

635715-01-4

Nicotine

Approved

Phase 4,Not Applicable

54-11-5

89594 942

Benzocaine

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

1994-09-7, 94-09-7

2337

tannic acid

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

1401-55-4

Amphotericin B

Approved, Investigational

Phase 4,Phase 3,Phase 2

1397-89-3

5280965 14956

Tyrosine

Approved, Investigational, Nutraceutical

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

60-18-4

6057

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

59-30-3

6037

Interventional clinical trials:

(show top 50) (show all 2062)

#	Name	Status	NCT ID	Phase	Drugs
1	Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients	Unknown status	NCT02690922	Phase 4	Dasatinib;prednisone;dexamethasone;methotrexate
2	Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia	Unknown status	NCT01990807	Phase 4	Idarubicin(IDA)
3	The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia	Unknown status	NCT00846703	Phase 4	6-mercaptopurine, Methotrexate;6-mercaptopurine, Methotrexate, Vincristine, Dexamethasone
4	German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia	Unknown status	NCT00198978	Phase 4	Cyclophosphamide;Dexamethasone / Prednisolone;Cytarabine;Idarubicin;Granulocyte-Colony-Stimulating Factor;Mercaptopurine;Methotrexate;Rituximab;HDARAC;Vincristine;Depocyte;Asparaginase
5	Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003	Unknown status	NCT00222612	Phase 4	Standard childhood UK ALL protocol;Intensified treatment including Capizzi maintenance
6	German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)	Unknown status	NCT00198991	Phase 4	Cyclophosphamide;Dexamethasone;Vincristine;daunorubicin;Asparaginase;Methotrexate;Cytarabine;Mercaptopurine;G-CSF;Vindesine;VP16;Prednisolone;Adriamycin;Thioguanine;VM26;Idarubicin;Fludarabine;Cladribine
7	Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study	Unknown status	NCT02894645	Phase 4	Prednisolone;Dexamethasone;L-Asparaginase;Vincristine;Methotrexate;Daunorubicin;Doxorubicin;Cyclophosphamide;Cytarabine;6-Mercaptopurine;Thioguanine;Fludarabine;Imatinib
8	Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses	Unknown status	NCT00192673	Phase 4	PEG-asparaginase
9	HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL	Unknown status	NCT01873807	Phase 4	IDA;CTX;VP-16
10	Intensification Therapy of Mature B-ALL, Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults	Unknown status	NCT00797810	Phase 4	Rituximab
11	Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission	Unknown status	NCT01901666	Phase 4	Growth Hormone
12	German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults	Completed	NCT00199017	Phase 4	Dexamethasone/Prednisolone;Cyclophosphamide;Vincristine;Daunorubicin;Asparaginase;G-CSF;Mercaptopurine;Cytarabine;Methotrexate;VP16;Vindesine;Adriamycin;Thioguanine;HDARAC;Cladribine
13	Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults	Completed	NCT00199082	Phase 4	Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone/Prednisolone;VP16;Ifosfamide;Methotrexate;G-CSF;Rituximab;Vincristine/Vindesine
14	Bone Marrow Transplantation in Treating Patients With Hematologic Cancer	Completed	NCT00003398	Phase 4	cyclophosphamide;thiotepa
15	Pulses of Vincristine and Dexamethasone in BFM Protocols for Children With Acute Lymphoblastic Leukemia	Completed	NCT00411541	Phase 4	vincristine;dexamethasone
16	Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia	Completed	NCT01358253	Phase 4	Cyclophosphamide;Doxorubicin;Vincristine;Dexamethasone;Cytarabine;Methotrexate;Rituximab;6-Mercaptopurine;Prednisone;L-asparaginase
17	LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia	Completed	NCT00526409	Phase 4	Prednisolone;Daunorubicin;Vincristine;L-Asparaginase;Cyclophosphamide;Methotrexate;Cytosine Arabinoside
18	PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia	Completed	NCT00494897	Phase 4	Asparaginase;Cyclophosphamide;Cytarabine;Daunorubicin;Mercaptopurine;Prednisone;Vincristine;Methotrexate
19	Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia	Completed	NCT00199095	Phase 4	Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone;Idarubicin;Ifosfamide;Methotrexate;Mercaptopurine;VM26;Vincristine
20	LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive	Completed	NCT00526305	Phase 4	Vincristine;Daunorubicin;Prednisone;L-Asparaginase;Mitoxantrone;Cytosine Arabinoside;Hydrocortisone;Mercaptopurine;Cyclophosphamide;Dexamethasone
21	ALL-REZ BFM 2002: Multi-Center Study for Children With Relapsed Acute Lymphoblastic Leukemia	Completed	NCT00114348	Phase 4
22	German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)	Completed	NCT00199069	Phase 4	Asparaginase;Vincristine;Daunorubicin, Adriamycin;Cyclophosphamide;Ifosfamide;Cytarabine;Mitoxantrone;Methotrexate;6-Mercaptopurine;6-Thioguanine;VM26;Dexamethasone / Prednisolone
23	German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)	Completed	NCT00199056	Phase 4	Dexamethasone / Prednisolone;Cyclophosphamide;Methotrexate;Vincristine / Vindesine;Daunorubicin;Asparaginase;G-CSF;Cytarabine;6-Mercaptopurine;VP16;Adriamycin;Thioguanine;VM26;Idarubicin;Fludarabine;Ifosfamide
24	Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab	Completed	NCT00199004	Phase 4	Cyclophosphamide;Dexamethasone / Prednisolone;Vincristine;Daunorubicin;Asparaginase;Methotrexate;Cytarabine;Mercaptopurine;G-CSF;Vindesine;VP16;Adriamycin;Thioguanine;VM26;Rituximab
25	Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome	Completed	NCT01200355	Phase 4	micafungin;posaconazole
26	Learning Impairments Among Survivors of Childhood Cancer	Completed	NCT00576472	Phase 4	Methylphenidate
27	LAL-BR/2001: Study Treatment to Low Risk ALL	Completed	NCT00526175	Phase 4	Prednisone;Vincristine;Daunorubicin;L-Asparaginase;Cyclophosphamide;Methotrexate;Cytosine Arabinoside;Mercaptopurine;VP-16
28	Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL	Completed	NCT02314273	Phase 4	rhIL-11
29	The Study on the Pharmacokinetics of PEG-rhG-CSF in Children and Adolescents	Completed	NCT02953730	Phase 4	PEG-rhG-CSF
30	Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase	Completed	NCT01061177	Phase 4	Nilotinib
31	A Clinical Trial of Decitabine in Relapsed or Refractory T-lymphoblastic Lymphoma	Recruiting	NCT03558412	Phase 4	Decitabine
32	ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors	Recruiting	NCT02938741	Phase 4	Anti－human Thymoglobulin;Placebo
33	Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia	Recruiting	NCT02618109	Phase 4
34	Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years)	Recruiting	NCT01366898	Phase 4	Dexamethasona, Idarubicine, ARA-C, Methotrexate
35	A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients	Recruiting	NCT03677596	Phase 4	inotuzumab ozogamicin-dose level 2;Inotuzumab ozogamicin-dose level 1
36	Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE	Recruiting	NCT01491763	Phase 4	Imatinib
37	Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid	Recruiting	NCT01906671	Phase 4	Xaluprine;Puri-Nethol
38	PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years	Recruiting	NCT01358201	Phase 4	vINCRISTINE;Dexamethasone;Methotrexate;Cytosine arabinoside
39	ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)	Recruiting	NCT02670564	Phase 4
40	Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia	Recruiting	NCT02036489	Phase 4	Vincristine;Daunorubicin;Prednisone;L-asparaginase;Ciclophosphamide;Metotrexate;ARA-C;Hidrocortisone;Mercaptopurine;VP-16;Dexametasone
41	G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor	Recruiting	NCT02933333	Phase 4
42	Treatment of High Risk Adult Acute Lymphoblastic Leukemia	Active, not recruiting	NCT00853008	Phase 4	Vincristine;Daunorubicin;Prednisone;Mitoxantrone;Cytosine Arabinoside;Dexamethasone;Methotrexate (MTX);Cytarabine;ASP;Mercaptopurine;Teniposide;Hydrocortisone
43	Vaccinating Children After Chemotherapy	Active, not recruiting	NCT02447718	Phase 4
44	Determinants of Mercaptopurine Toxicity in Paediatric Acute Lymphoblastic Leukemia Maintenance Therapy	Enrolling by invitation	NCT03920813	Phase 4	Mercaptopurine
45	A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT	Enrolling by invitation	NCT03176849	Phase 4
46	ProphyALL - Study on the Safety of Liposomal Amphotericin B to Prevent Antifungal Infections in Elderly Patients With Acute Lymphoblastic Leukemia	Terminated	NCT00386997	Phase 4	liposomal amphotericin B (AmBisome®)
47	Atomoxetine for Children With Acquired Attentional Disorders Following Completion of Chemotherapy for ALL	Terminated	NCT00299234	Phase 4	Atomoxetine
48	Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma	Unknown status	NCT00004228	Phase 3	asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;prednisone;thioguanine;vincristine sulfate
49	Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma	Unknown status	NCT00003650	Phase 3	asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisone;vincristine sulfate
50	Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain	Unknown status	NCT01316744	Phase 3	ketamine hydrochloride

Search NIH Clinical Center for Lymphoblastic Lymphoma

Inferred drug relations via UMLS ⁷⁴ / NDF-RT ⁵² :

asparaginase

cyclophosphamide

idarubicin

idarubicin hydrochloride

ifosfamide

mercaptopurine

pegaspargase

sargramostim

Cell-based therapeutics:

Data from LifeMap, the Embryonic Development and Stem Cells Database

Read about Lymphoblastic Lymphoma cell therapies at LifeMap Discovery.

Stem-cell-based therapeutic approaches for Lymphoblastic Lymphoma:

	Blood stem cell transplantation for hematological diseases
	Hematopoietic stem cells for treatment of hematologic malignancies
	Peripheral blood stem cells for treatment of hematologic malignancies

Embryonic/Adult Cultured Cells Related to Lymphoblastic Lymphoma:

	Peripheral blood-derived hematopoietic stem cells (family)
	Bone marrow-derived hematopoietic stem cells

Sources

Genetic Tests for Lymphoblastic Lymphoma

Sources

Anatomical Context for Lymphoblastic Lymphoma

MalaCards organs/tissues related to Lymphoblastic Lymphoma:

⁴²

T Cells, B Cells, Bone, Bone Marrow, Myeloid, B Lymphoblasts, Kidney

The Foundational Model of Anatomy Ontology organs/tissues related to Lymphoblastic Lymphoma:

²⁰

Primarily Lymph Nodes Or

Sources

Publications for Lymphoblastic Lymphoma

Articles related to Lymphoblastic Lymphoma:

(show top 50) (show all 692)

#	Title	Authors	Year
1	Non-leukemic pediatric mixed phenotype acute leukemia/lymphoma: Genomic characterization and clinical outcome in a prospective trial for pediatric lymphoblastic lymphoma. ( 30578714 )	Martin-Guerrero I...Oschlies I	2019
2	FDG PET/CT Demonstrated Precursor B-cell Lymphoblastic Lymphoma in a Pediatric Patient With Hemophilia B. ( 31021910 )	Liu Z...Yang J	2019
3	Steroid-induced Bradycardia During Induction Chemotherapy in Children and Young Adults Diagnosed With Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma. ( 30994505 )	Duffy C...Borinstein SC	2019
4	A Case of Renal Involvement in B Lymphoblastic Lymphoma Leukemia. ( 30775881 )	Zhang L...Liu JJ	2019
5	Expression and significance of CD47, PD1 and PDL1 in T-cell acute lymphoblastic lymphoma/leukemia. ( 30466764 )	Yang K...Xi Y	2019
6	A Young Man with a Mass: Non-Early Precursor T-Cell Lymphoblastic Lymphoma. ( 30138599 )	Jiang Y...Kanaan Z	2019
7	B-lymphoblastic lymphoma with TCF3-PBX1 fusion gene. ( 30262566 )	Kubota-Tanaka M...Takagi M	2019
8	T-lymphoblastic lymphoma after previous thymoma: how NGS helps establishing the diagnosis and procures new insights. ( 30301393 )	Le Clef Q...Tzankov A	2019
9	Orbital precursor B-lymphoblastic lymphoma involving the extraocular muscles in a 56-year-old male and a review of the literature. ( 30675202 )	Ejstrup R...Heegaard S	2019
10	Cutaneous involvement as the first manifestation of T-lymphoblastic lymphoma and review of the literature. ( 30680766 )	Montes-Torres A...Adrados M	2019
11	Acral Involvement of Lymphoblastic Lymphoma Revealed on FDG PET/CT. ( 30688741 )	Wen Z...Zhuang H	2019
12	Sustained Response to Imatinib in a Pediatric Patient with Concurrent Myeloproliferative Disease and Lymphoblastic Lymphoma Associated with a CCDC88C-PDGFRB Fusion Gene. ( 30726835 )	Bielorai B...Toren A	2019
13	Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma. ( 30742097 )	V?zquez-Dom?nguez I...Fern?ndez-Piqueras J	2019
14	S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma. ( 30805584 )	Mar?n-Rubio JL...Villa-Morales M	2019
15	Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities. ( 30809797 )	Burkhardt B...Hermiston ML	2019
16	Clinical Predictors and Prognostic Model for Pediatric Lymphoblastic Lymphoma Treated With Uniform BFM90 Protocol: A Single-Center Experience of 65 Patients From Asia. ( 30905539 )	Patel A...Bakhshi S	2019
17	Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma. ( 30914738 )	L?pez-Nieva P...Fern?ndez-Piqueras J	2019
18	Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review. ( 30915242 )	Khurana S...Roy V	2019
19	Circ-LAMP1 promotes T-cell lymphoblastic lymphoma progression via acting as a ceRNA for miR-615-5p to regulate DDR2 expression. ( 30922709 )	Deng L...Yang F	2019
20	Complete Blood Count Score Model Integrating Reduced Lymphocyte-Monocyte Ratio, Elevated Neutrophil-Lymphocyte Ratio, and Elevated Platelet-Lymphocyte Ratio Predicts Inferior Clinical Outcomes in Adult T-Lymphoblastic Lymphoma. ( 30952822 )	Feng X...Zhang M	2019
21	Prognostic and predictive value of a microRNA signature in adults with T-cell lymphoblastic lymphoma. ( 30953029 )	Tian XP...Cai QQ	2019
22	Double-hit pancreatic B-lymphoblastic lymphoma with a variant translocation t(2;18)(p11;q21). ( 30963474 )	Yamamoto K...Minami H	2019
23	Endovascular mechanical thrombectomy for superior sagittal sinus thrombosis in a patient with T-lymphoblastic lymphoma treated with L-asparaginase. ( 31092500 )	Bond A...Mortimer A	2019
24	Diagnostic challenges in T-lymphoblastic lymphoma, early T-cell precursor acute lymphoblastic leukemia or mixed phenotype acute leukemia: A case report. ( 30313079 )	Wang P...Feng Y	2018
25	Coexistence of T-cell lymphoblastic lymphoma and acute myeloid leukemia mimicking acute lymphocytic leukemia. ( 30004087 )	Liu K...Li W	2018
26	T-Cell Acute Lymphoblastic Lymphoma Presenting as Dissecting Cellulitis and Cavernous Sinus Syndrome. ( 30418330 )	Mattingly JJ...Yalamanchili SS	2018
27	Outcome of adult T-lymphoblastic lymphoma depends on ALL-type chemotherapy, prognostic factors, and performance of allogeneic hematopoietic stem cell transplantation. ( 29995776 )	Hu M...Jin J	2018
28	Allogeneic hematopoietic stem cell transplantation should be in preference to conventional chemotherapy as post-remission treatment for adults with lymphoblastic lymphoma. ( 29712994 )	Yang L...Luo Y	2018
29	Secondary Thymoma among Adult Treated For Acute Lymphoblastic Lymphoma/Leukemia: Report of a Case and Review of the Literature. ( 30607194 )	Bendari M...Quessar A	2018
30	Bcl-2 maturation pattern in T-cells distinguishes thymic neoplasm/hyperplasia, T-lymphoblastic lymphoma, and reactive lymph nodes. ( 28718205 )	Ward N...Smith MD	2018
31	Immunophenotypic analysis of adult patients with T-cell lymphoblastic lymphoma treated with hyper-CVAD. ( 28778131 )	Kato H...Kinoshita T	2018
32	Myeloid Neoplasia and Lymphoblastic Lymphoma with Eosinophilia After Radioactive Iodine: A Case Report. ( 28958974 )	B?y?k?im?ek M...Ergin M	2018
33	Lymphoblastic Lymphoma Involving Multiple Vertebrae. ( 28962960 )	Li D...Wu Z	2018
34	Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma. ( 29047158 )	Abaza Y...Ravandi F	2018
35	Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group. ( 29090524 )	Rau RE...Hunger SP	2018
36	FGFR1 translocation with concurrent myeloproliferative neoplasm, systemic mastocytosis, and lymphoblastic lymphoma: a case report. ( 29107667 )	Chang K...Lin CW	2018
37	Pediatric Patient With T-Cell Lymphoblastic Lymphoma and Acute Vision Loss. ( 29121170 )	Chen TH...Shah HA	2018
38	Case Report: A Cryptosporidium infection in a patient with relapsed T-lymphoblastic lymphoma undergoing allogeneic stem cell transplantation. ( 29140544 )	Schiller J...Fl?mann R	2018
39	Indolent T-lymphoblastic proliferation concomitant with acinic cell carcinoma mimicking T-lymphoblastic lymphoma: case report and literature review. ( 29143359 )	Yasuda H...Komatsu N	2018
40	Successful Treatment of Mediastinal γδ T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation. ( 29200146 )	Hori D...Kobayashi K	2018
41	Patients over 40 years old with precursor T-cell lymphoblastic lymphoma have different prognostic factors comparing to the youngers. ( 29348421 )	Dong M...Chen Q	2018
42	Acute lymphoblastic leukemia and lymphoblastic lymphoma in adolescents and young adults. ( 29418064 )	McNeer JL...Bleyer A	2018
43	Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial-mesenchymal transition via regulating the PI3K/AKT/mTOR pathway. ( 29483777 )	Huang Y...Guo Y	2018
44	Myositis in bilateral calves mimicking lymphoma on interim PET/CT in a patient with T-lymphoblastic lymphoma. ( 29590432 )	Seo M...Park SH	2018
45	Precursor T-Lymphoblastic Lymphoma Associated with t(8;9)(p11.2;q33): A Case Report and Review of the Literature. ( 29614500 )	Lv H...Wang Y	2018
46	Transformation of T-Cell Acute Lymphoblastic Lymphoma to Peripheral T-Cell Lymphoma: A Report of Two Cases. ( 29682368 )	Markow M...Hussaini MO	2018
47	A case report of B lymphoblastic lymphoma with brain metastases: Clinical and pathological significance of head trauma misdiagnosis. ( 29768334 )	Shi J...Wu S	2018
48	Successful treatment of pulmonary invasive fungal infection by Penicillium non-marneffei in lymphoblastic lymphoma: case report and literature review. ( 29881585 )	Ram?rez I...Cardona R	2018
49	Terminal deoxynucleotidyl transferase (TdT)-negative T-cell lymphoblastic lymphoma with loss of the T-cell lineage-specific marker CD3 at relapse: a rare entity with an aggressive outcome. ( 29884716 )	Hassan M...Qamar MA	2018
50	Philadelphia chromosome-positive lymphoblastic lymphoma-Is it rare or underdiagnosed? ( 29913129 )	Alshomar A...El Fakih R	2018

Sources

Genes for Lymphoblastic Lymphoma

Genes related to Lymphoblastic Lymphoma (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	ZMYM2	Zinc Finger MYM-Type Containing 2	Protein Coding	32.13	DISEASES inferred ¹⁵ GeneCards inferred via : Disorders Publications (show sections)
2	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	30.13	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	11190795 7503935
3	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	28.09	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Disorders (show sections)	11919391
4	TAL1	TAL BHLH Transcription Factor 1, Erythroid Differentiation Factor	Protein Coding	28.08	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	9116269 9171354
5	BCL6	BCL6 Transcription Repressor	Protein Coding	27.73	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	11133771 9310496
6	NOTCH1	Notch Receptor 1	Protein Coding	27.65	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	18663146
7	CDKN2B	Cyclin Dependent Kinase Inhibitor 2B	Protein Coding	27.03	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	7882348 8656689 8637248 (more) 15475071
8	FLI1	Fli-1 Proto-Oncogene, ETS Transcription Factor	Protein Coding	26.48	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	19349856 11117787
9	CEP85L	Centrosomal Protein 85 Like	Protein Coding	26.32	GeneCards inferred via : Disorders Expressions (show sections)
10	MPO	Myeloperoxidase	Protein Coding	25.75	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	7513945 8037168
11	DNTT	DNA Nucleotidylexotransferase	Protein Coding	25.1	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	11190795 18480005 7937725 (more) 9042293 9175304 16217262 9353824 19633642 18341382 17885674 9343323 9227346 9422326 1996546 1859892 9110287
12	MME	Membrane Metalloendopeptidase	Protein Coding	23.02	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	TRB	T Cell Receptor Beta Locus	Protein Coding	22.46	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	1701841 15132850
14	CD5	CD5 Molecule	Protein Coding	22.42	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
15	KMT2A	Lysine Methyltransferase 2A	Protein Coding	22.16	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	10602439
16	CD7	CD7 Molecule	Protein Coding	20.59	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	1701841 7741140

Sources

Variations for Lymphoblastic Lymphoma

Sources

Expression for Lymphoblastic Lymphoma

Search GEO for disease gene expression data for Lymphoblastic Lymphoma.

Sources

Pathways for Lymphoblastic Lymphoma

Pathways related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	12.17	BCL6 FLI1 MPO PTPRC TAL1
2	Transcriptional misregulation in cancer ³⁸	11.89	BCL6 FLI1 KMT2A MPO
3	Hematopoietic cell lineage ³⁸	11.44	CD5 CD7 DNTT MME
4	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁶	11.09	CD5 MME MPO NOTCH1 PTPRC
5	B Cell Development Pathways ⁶⁶	10.98	BCL6 CD5 MME PTPRC

Sources

GO Terms for Lymphoblastic Lymphoma

Biological processes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of hematopoietic stem cell differentiation	GO:1902036	9.4	KMT2A TAL1
2	cellular response to extracellular stimulus	GO:0031668	9.37	CDKN2B PTPRC
3	embryonic hemopoiesis	GO:0035162	9.32	KMT2A TAL1
4	megakaryocyte development	GO:0035855	9.26	FLI1 TAL1
5	generation of neurons	GO:0048699	9.16	FGFR1 TAL1
6	megakaryocyte differentiation	GO:0030219	8.96	CDKN2B TAL1
7	regulation of cell proliferation	GO:0042127	8.92	BCL6 FGFR1 NOTCH1 TAL1

Molecular functions related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	heparin binding	GO:0008201	9.33	FGFR1 MPO PTPRC
2	RNA polymerase II distal enhancer sequence-specific DNA binding	GO:0000980	9.13	FLI1 KMT2A TAL1
3	chromatin binding	GO:0003682	9.02	BCL6 FLI1 MPO NOTCH1 TAL1

Sources

Sources for Lymphoblastic Lymphoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia

Lymphoblastic Lymphoma

Aliases & Classifications for Lymphoblastic Lymphoma

MalaCards integrated aliases for Lymphoblastic Lymphoma:

Classifications:

External Ids:

Summaries for Lymphoblastic Lymphoma

Related Diseases for Lymphoblastic Lymphoma

Diseases related to Lymphoblastic Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Lymphoblastic Lymphoma:

Symptoms & Phenotypes for Lymphoblastic Lymphoma

GenomeRNAi Phenotypes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Lymphoblastic Lymphoma:

Drugs & Therapeutics for Lymphoblastic Lymphoma

FDA approved drugs:

Drugs for Lymphoblastic Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 74 / NDF-RT 52 :

Cell-based therapeutics:

Genetic Tests for Lymphoblastic Lymphoma

Anatomical Context for Lymphoblastic Lymphoma

MalaCards organs/tissues related to Lymphoblastic Lymphoma:

The Foundational Model of Anatomy Ontology organs/tissues related to Lymphoblastic Lymphoma:

Publications for Lymphoblastic Lymphoma

Articles related to Lymphoblastic Lymphoma:

Genes for Lymphoblastic Lymphoma

Genes related to Lymphoblastic Lymphoma (0 elite genes):

Variations for Lymphoblastic Lymphoma

Expression for Lymphoblastic Lymphoma

Pathways for Lymphoblastic Lymphoma

Pathways related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

GO Terms for Lymphoblastic Lymphoma

Biological processes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

Molecular functions related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

Sources for Lymphoblastic Lymphoma

Inferred drug relations via UMLS ⁷⁴ / NDF-RT ⁵² :