MCID: LYM005
MIFTS: 35

Lymphocele

Categories: Immune diseases

Aliases & Classifications for Lymphocele

MalaCards integrated aliases for Lymphocele:

Name: Lymphocele 12 43 15 71
Lymphocele Adverse Event 71
Lymph Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4347
MeSH 43 D008210
NCIt 49 C78442
SNOMED-CT 67 234109007
UMLS 71 C0024248 C1963162

Summaries for Lymphocele

MalaCards based summary : Lymphocele, also known as lymphocele adverse event, is related to acute kidney tubular necrosis and campomelia, cumming type. An important gene associated with Lymphocele is KLK3 (Kallikrein Related Peptidase 3). The drugs Heparin and Hemostatics have been mentioned in the context of this disorder. Affiliated tissues include kidney, lymph node and prostate.

Wikipedia : 74 A lymphocele is a collection of lymphatic fluid within the body not bordered by epithelial lining. It is... more...

Related Diseases for Lymphocele

Diseases related to Lymphocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 acute kidney tubular necrosis 30.4 CABIN1 ALB
2 campomelia, cumming type 12.2
3 hereditary lymphedema i 10.5
4 hydronephrosis 10.5
5 endometrial cancer 10.4
6 submandibular gland cancer 10.4 KLK3 CABIN1
7 exudative vitreoretinopathy 6 10.3 MTOR CABIN1
8 cervical carcinosarcoma 10.3 MAPK8IP2 MAPK8IP1
9 thrombophilia due to thrombin defect 10.3
10 ureteral obstruction 10.3
11 end stage renal disease 10.3
12 ileus 10.3
13 cervix small cell carcinoma 10.3 MAPK8IP2 MAPK8IP1
14 female urethral cancer 10.3 KLK3 ERVMER34-1
15 sigmoid disease 10.3 MAPK8IP2 MAPK8IP1
16 cervical adenosquamous carcinoma 10.3 MAPK8IP2 MAPK8IP1
17 hypertensive encephalopathy 10.3 CABIN1 ALB
18 vaginal discharge 10.2 MAPK8IP2 MAPK8IP1
19 urinary tract obstruction 10.2
20 pyuria 10.2 KLK3 ALB
21 hemorrhoid 10.2 KLK3 ALB
22 ovarian cancer 10.2
23 ascites, chylous 10.2
24 cervical cancer 10.2
25 pulmonary embolism 10.2
26 hantavirus hemorrhagic fever with renal syndrome 10.2 CABIN1 ALB
27 radiation cystitis 10.2 MAPK8IP2 MAPK8IP1 KLK3
28 hemorrhagic cystitis 10.2 CABIN1 ALB
29 oxirane allergy 10.2 ERVMER34-1 ALB
30 prostate neuroendocrine neoplasm 10.2 KLK3 FOLH1
31 bladder lateral wall cancer 10.2 KLK3 FOLH1
32 pneumocystosis 10.2 CABIN1 ALB
33 renal tuberculosis 10.2 STK10 ERVMER34-1
34 bladder tuberculosis 10.1 STK10 ERVMER34-1
35 urethral stricture 10.1 KLK3 FOLH1
36 paralytic ileus 10.1 ERVMER34-1 ALB
37 suppressor of tumorigenicity 3 10.1
38 lymphoproliferative syndrome 10.1
39 47,xyy 10.1
40 back pain 10.1
41 pyelitis 10.1 CABIN1 ALB
42 pelvic varices 10.1 KLK3 ALB
43 cholecystolithiasis 10.1 STK10 ERVMER34-1
44 congenital anomalies of kidney and urinary tract 2 10.1 STK10 ERVMER34-1
45 aortic aneurysm, familial abdominal, 1 10.0
46 bladder cancer 10.0
47 lipomatosis, multiple 10.0
48 microvascular complications of diabetes 3 10.0
49 microvascular complications of diabetes 4 10.0
50 microvascular complications of diabetes 6 10.0

Graphical network of the top 20 diseases related to Lymphocele:



Diseases related to Lymphocele

Symptoms & Phenotypes for Lymphocele

Drugs & Therapeutics for Lymphocele

Drugs for Lymphocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
2 Hemostatics Phase 4
3 Coagulants Phase 4
4 Fibrinolytic Agents Phase 4
5 Anticoagulants Phase 4
6 calcium heparin Phase 4
7
lanreotide Approved Phase 3 108736-35-2
8
Somatostatin Approved, Investigational Phase 3 38916-34-6, 51110-01-1 53481605
9
Cisplatin Approved Phase 3 15663-27-1 2767 441203 84093
10 Hormone Antagonists Phase 3
11 Hormones Phase 3
12 Angiopeptin Phase 3
13 Fibrin Tissue Adhesive Phase 3
14
Pasireotide Approved Phase 2 396091-73-9 9941444
15
Thrombin Approved, Investigational
16
Octreotide Approved, Investigational 83150-76-9 383414 6400441
17 Pharmaceutical Solutions
18 Antineoplastic Agents, Hormonal

Interventional clinical trials:

(show all 39)
# Name Status NCT ID Phase Drugs
1 Effect of TachoSil® on Incidence of Symptomatic and Radiographic Lymphoceles After Extended Pelvic Lymph Node Dissection in Prostate and Bladder Cancer. Completed NCT02001857 Phase 4 1 TachoSil hemostatic sponge (9,5 cm x 4,8 cm) placed on each side on the external iliac artery.
2 Does Intraoperative Application of TachoSil Reduce the Number of Lymphocele After Pelvic Lymphadenectomy? Completed NCT03752606 Phase 4
3 A Randomized Controlled Trial for PREvention of VENous ThromboEmbolism Following Radical Prostatectomy (PREVENTER Trial) Terminated NCT03006562 Phase 4 Subcutaneous Heparin
4 Prevention of Pelvic Lymphocele by Floseal During Pelvic Lymphadenectomy for Gynecologic Cancer: a Pilot Study Unknown status NCT01974193 Phase 3 Floseal
5 A Collagen-Fibrin Patch (Tachosil®) for the Prevention of Symptomatic Lymphoceles After Pelvic Lymphadenectomy in Women With Gynecologic Malignancies: a Randomized Clinical Trial Completed NCT01470677 Phase 3 Tachosil fibrin patch
6 Evaluation of the Efficacity of Lanreotide LP 90 mg to Minimized the Lymphorrhea Post Axillary Lymphadenectomy in Breast Cancer Completed NCT00630695 Phase 3 Lanreotide LP 90;Placebo lanreotide
7 Efficacy of a Fibrin Sealant (Tissucol Duo®) for the Prevention of Lymphocele After Laparoscopic Pelvic Lymphadenectomy Due to Gynaecological Cancer: a Randomised Controlled Trial Completed NCT03914963 Phase 3
8 Application of the Biological Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplant Completed NCT01631448 Phase 3
9 Observation Versus Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer: A Phase 3 Prospective Multi-institutional Randomised Controlled Trial Recruiting NCT03071289 Phase 3 Cisplatin
10 Evaluation of the Effect of Pasireotide LAR Administration in the Lymphocele Prevention After Axillary Node Dissection for Breast Cancer Completed NCT01356862 Phase 2 PASIREOTIDE;PLACEBO
11 PREvention of Post-mastectomy LYMphoceles by PAdding. A Randomized Prospective Multicenter Study Unknown status NCT02894021
12 Prospective Randomized Trial on Laparoscopic Radical Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Early Stage Cervical Cancer (FIGO Stages IA2-IB1-IIA<2cm) and Advanced Stage Cervical Cancer (FIGO Stages IB2-IIA>2 Cm-IIB) Submitted to NACT With Complete Clinical Response: Thunderbeat Technology Versus Standard Bipolar Electro Surgery Unknown status NCT01717781
13 Prospective Randomized Trial on Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Endometrial Cancer FIGO Stage IB-II: Thunderbeat Technology Versus Standard Bipolar Electro-surgery. Unknown status NCT01717794
14 Assistant Lecturer of Urology in Assiut University Unknown status NCT03338140
15 THE ROLE OF FLOSEAL IN THE PREVENTION OF LYMPHOCELE AND LYMPHATIC ASCITES AFTER LYMPH NODE DISSECTION FOR GYNECOLOGIC CANCER: A RANDOMIZED CONTROLLED TRIAL Completed NCT01679483 FloSeal application
16 Prospective Open Randomized Study to Evaluate the Efficiency of Prophylactic Fenestration of the Peritoneum in Kidney Transplantation in Preventing the Occurrence of Postoperative Lymphoceles Completed NCT01206868
17 A Randomized Control Trial for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection Completed NCT02476357
18 Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecological Cancer Completed NCT03765320
19 Application of Cold Plasma Energy for Reduction of Lymphoceles Following Pelvic Lymph Node Dissection During Robot-Assisted Radical Prostatectomy Completed NCT02658851
20 A Pilot Clinical Trial for the Prevention of Lymphoceles After Robotic Pelvic Lymph Node Dissections for Prostate Malignancies Using the da Vinci® EndoWrist® Oneā„¢ Vessel Sealer Completed NCT02035475
21 A Randomized Study Evaluating the Efficacy of the Synthetic Adhesive Solution Ifabond, in Reducing Seroma Formation Post Surgery in Breast Cancer Patients, When Used in Partial Mastectomy With or Without Axillary Lymph Node Dissection Completed NCT01742975
22 Routine Use of Fibrin Sealant Does Not Reduce Postoperative Wound Complications in Patients Undergoing Renal Transplantation: A Randomized Controlled Trial Completed NCT00910052
23 The Impact of Bipolar Energy Modalities on Peri-operative Outcome During Laparoscopic Staging Surgery of Gynecologic Cancers: A Randomized Clinical Trial Completed NCT02822820
24 Prevalence, Complications and Risk Factors for Lymphedema After Pelvic and Paraaortic Lymphadenectomy in Primary Radical Surgery for Early Stage Endometrial Carcinoma. Completed NCT02115477
25 Study to Evaluate the Efficacy of Early Detection of Lower Extremity Lymphedema After Lymphadenectomy in Gynecological Cancer and Implantation of the Protocol Completed NCT03917771
26 Prospective Randomized Trial on2D Versus 3D Laparoscopic Radical Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Early Stage Cervical Cancer (FIGO Stages IA2-IB1-IIA<2cm) and Advanced Stage Cervical Cancer (FIGO Stages IB2-IIA>2 Cm-IIB) Submitted to NACT With Complete Clinical Response. Completed NCT02320578
27 Whole Body Bone Scan vs 18F-Choline PET/CT, Better Detection of Bone Metastases in Prostate Cancer Patients, PROSTAGE I Completed NCT02232685
28 Prospective Randomized Trial on 2D Versus 3D Laparoscopic Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Endometrial Cancer FIGO Stage IB-II Completed NCT02320565
29 Choline PET/CT vs. Dual Time Point FDG PET/CT. Better Detection of Bone and Lymph Node Metastasis in Prostate Cancer Patients, PROSTAGE II Completed NCT02232724
30 Application of Thrombin Gel Matrix for the Prevention of Lymphocele in Patients With Endometrial Cancer. Recruiting NCT04205864 Thrombi-Gel
31 Management of Symptomatic Post-operative Lymphocele With an Patient-controlled, Vascular Catheter: A Validation Study Recruiting NCT02800980
32 The Effect of a Peritoneal Iliac Flap on Lymphocele Formation After Robotic Radical Prostatectomy Recruiting NCT03567525
33 Hemopatch to Prevent Lymphatic Leak After Robotic Prostatectomy and Pelvic Lymph Node Dissection: a Randomized Controlled Trial Recruiting NCT04185922
34 A Prospective Observational Trial on Sentinel Lymph Node Biopsy in Patients With Early Stage Cervical Cancer Recruiting NCT02494063
35 Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s): is One-sided Salvage Extended Lymph Node Dissection Enough Recruiting NCT04271579
36 PREventive Effect of FENestration With and Without Clipping on Post-Kidney Transplantation Lymphatic Complications: PREFEN Trial Not yet recruiting NCT03682627
37 Evaluation of Impact of Sandostatin® Injection Before Axillary Clearance on Lymphocele Formation In Patients With Breast Cancer Terminated NCT03791736
38 A Pilot Clinical Trial for the Prevention of Postoperative Lymphoceles Using Absorbable Micorporous Polysaccharide Hemosphere Particles During Robotic Assisted Prostatectomy With Lymph Node Dissection Terminated NCT01644136
39 Choline PET/CT vs. MeAIB PET/CT. Better Detection of Bone and Lymph Node Metastases in Prostate Cancer Patients, PROSTAGE III Withdrawn NCT02232672

Search NIH Clinical Center for Lymphocele

Cochrane evidence based reviews: lymphocele

Genetic Tests for Lymphocele

Anatomical Context for Lymphocele

MalaCards organs/tissues related to Lymphocele:

40
Kidney, Lymph Node, Prostate, Breast, Bone, Liver, Heart

Publications for Lymphocele

Articles related to Lymphocele:

(show top 50) (show all 1168)
# Title Authors PMID Year
1
Transposition of the left vertebral artery during endovascular stent-graft repair of the aortic arch. 61
31301891 2020
2
Relation Between Wound Complication and Lymphocele After Kidney Transplantation: A Monocentric Study. 61
32299707 2020
3
Can we predict who will need lymphocele drainage following robot assisted laparoscopic prostatectomy (RALP)? 61
31422556 2020
4
Treatment Outcomes in Patients with Symptomatic Lymphoceles Following Radical Prostatectomy Depend Upon Size and Presence of Infection. 61
32562773 2020
5
Consensus on definition and severity grading of lymphatic complications after kidney transplantation. 61
32227483 2020
6
Hybrid procedures in the dialysis fistula aneurysm treatment. 61
32522136 2020
7
Percutaneous treatment of vascular access-site complications: a ten years' experience in two centres. 61
32507937 2020
8
A Case Series of Retroperitoneal Lymphocele Following Anterior Lumbar Interbody Fusion. 61
32389867 2020
9
Spontaneous lymphocele presenting with obstructive jaundice. 61
31866315 2020
10
Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial. 61
32444264 2020
11
Comparison of lymphatic complications between sentinel node navigation surgery and pelvic lymphadenectomy in patients with cervical cancer. 61
32104889 2020
12
Risk factors for lymphatic complications following lymphadenectomy in patients with endometrial cancer. 61
32416891 2020
13
Utilization of a Peritoneal Interposition Flap to Prevent Symptomatic Lymphoceles After Robotic Radical Prostatectomy and Bilateral Pelvic Lymph Node Dissection. 61
32303137 2020
14
Lomboaortic Lymphadenectomy in Gynecological Oncology: Laparotomy, Laparoscopy or Robot-Assisted Laparoscopy? 61
32472415 2020
15
Diagnostic clues, pitfalls, and imaging characteristics of '-celes' that arise in abdominal and pelvic structures. 61
32356005 2020
16
Transverse versus vertical groin incision for femoral artery approach. 61
32319682 2020
17
Imaging features, complications and differential diagnoses of abdominal cystic lymphangiomas. 61
32296900 2020
18
Early Postoperative Complications and Outcomes of Kidney Transplantation in Moderately Obese Patients. 61
32252995 2020
19
Short term outcomes of minimally invasive selective lateral pelvic lymph node dissection for low rectal cancer. 61
32426097 2020
20
A Case of Left Groin Lymphocele Postoperatively. 61
32351281 2020
21
Lymphovenous anastomosis (LVA) for treatment of iatrogenic lymphocele in the thigh. 61
32343453 2020
22
Peritoneal Flap in Robot-Assisted Radical Prostatectomy. 61
32449896 2020
23
Impact of kidney transplant morbidity on elderly recipients' outcomes. 61
32323169 2020
24
A Systematic Review and Meta-Analysis of Pelvic Drain Insertion After Robot-Assisted Radical Prostatectomy. 61
32037859 2020
25
Development of Ureteral Stenosis/Obstruction in Kidney Transplant. 61
32061424 2020
26
Conventional Lymphangiography (CL) in the Management of Postoperative Lymphatic Leakage (PLL): A Systematic Review. 61
32215900 2020
27
Lymphatic Leaks of the Thigh and Inguinal Region: Combined Plastic Surgery Approaches for an Effective Treatment Algorithm. 61
32118638 2020
28
Incidence of and risk factors for lymphocele formation after lateral pelvic lymph node dissection for rectal cancer: a retrospective study. 61
31454448 2020
29
Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair. 61
31176637 2020
30
Surgical Strategies for Lymphocele Prevention in Minimally Invasive Radical Prostatectomy and Lymph Node Dissection: A Systematic Review. 61
31797684 2020
31
Lipofilled Mini Dorsi Flap: An Efficient Less Invasive Concept for Immediate Breast Reconstruction. 61
32032119 2020
32
Treatment of lymphocele with negative pressure wound therapy post inguinal mass excision: A case-report. 61
31790951 2020
33
[Robot-assisted kidney transplantation]. 61
31832746 2020
34
Harmonic Focus Versus Conventional Electrocautery for Femoral Artery Exposure: a "Direct" Comparison on the Same Patients. 61
32123678 2020
35
Sclerotherapy With OK-432 for the Treatment of Symptomatic Lymphocele After Lymph Node Dissection: A Retrospective Comparative Cohort Study. 61
32000251 2020
36
Combined lymphovenous anastomosis and deep inferior epigastric perforator flap with lymphatic tissue preservation for defect reconstruction and lymphedema-lymphocele prevention after medial thigh sarcoma resection: A case report. 61
31951055 2020
37
Contemporary lymphatic interventions for post-operative lymphatic leaks. 61
32055491 2020
38
Bilateral abdominopelvic lymphoceles secondary to huge uterine leiomyomas: A case report. 61
31642137 2020
39
Predictors of symptomatic lymphocele after kidney transplantation. 61
31486950 2019
40
Polidocanol echosclerotherapy treatment for lymphocele: case report and review. 61
31921320 2019
41
Single cohort study: ABO-incompatible kidney transplant recipients have a higher risk of lymphocele formation. 61
31456076 2019
42
Effect of using magnifying loupe glasses on lymphocele formation and surgical outcomes in gynecologic oncology. 61
32231857 2019
43
A Comparison of Different Valgancyclovir Formulations in the Universal 6-Month Prophylaxis Against CMV Infection in Renal Transplant Recipients: A Randomized Single-Centre Study. 61
32109215 2019
44
A case of laparoscopic fenestration surgery for pelvic lymphocele occurring after laparoscopic radical prostatectomy. 61
31788150 2019
45
ABO-incompatible living-donor kidney transplantation: Study of 48 patients after desensitisation. 61
31208833 2019
46
Indocyanine green-enhanced fluorescence-guided video-assisted axillary surgery for chronic lymphocele. 61
30549254 2019
47
[Diagnosis and treatment of complications related with lymph-node dissection surgery: Lymphorrea, lymphocele and lymphedema.] 61
31579044 2019
48
Prophylactic abdominal or retroperitoneal drain placement in major uro-oncological surgery: a systematic review and meta-analysis of comparative studies on radical prostatectomy, cystectomy and partial nephrectomy. 61
31664510 2019
49
Sentinel lymph node biopsy in patients with malignant melanoma: analysis of post-operative complications. 61
31368164 2019
50
Robotic-assisted kidney transplant: a single center experience with median follow-up of 2.8 years. 61
31489478 2019

Variations for Lymphocele

Expression for Lymphocele

Search GEO for disease gene expression data for Lymphocele.

Pathways for Lymphocele

GO Terms for Lymphocele

Biological processes related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor-mediated endocytosis GO:0006898 9.33 MAPK8IP2 MAPK8IP1 ALB
2 positive regulation of endocytosis GO:0045807 8.96 MAPK8IP2 MAPK8IP1
3 regulation of JNK cascade GO:0046328 8.62 MAPK8IP2 MAPK8IP1

Molecular functions related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAP-kinase scaffold activity GO:0005078 8.62 MAPK8IP2 MAPK8IP1

Sources for Lymphocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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