MCID: LYM005
MIFTS: 35

Lymphocele

Categories: Immune diseases

Aliases & Classifications for Lymphocele

MalaCards integrated aliases for Lymphocele:

Name: Lymphocele 12 43 15 71
Lymphocele Adverse Event 71
Lymph Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4347
MeSH 43 D008210
NCIt 49 C78442
SNOMED-CT 67 12167004
UMLS 71 C0024248 C1963162

Summaries for Lymphocele

MalaCards based summary : Lymphocele, also known as lymphocele adverse event, is related to acute kidney tubular necrosis and campomelia, cumming type. An important gene associated with Lymphocele is KLK3 (Kallikrein Related Peptidase 3). The drugs Heparin and Calcium have been mentioned in the context of this disorder. Affiliated tissues include kidney, lymph node and prostate, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 74 A lymphocele is a collection of lymphatic fluid within the body not bordered by epithelial lining. It is... more...

Related Diseases for Lymphocele

Diseases related to Lymphocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)
# Related Disease Score Top Affiliating Genes
1 acute kidney tubular necrosis 30.4 CABIN1 ALB
2 campomelia, cumming type 12.2
3 hydronephrosis 10.5
4 lymphedema 10.4
5 submandibular gland cancer 10.4 KLK3 CABIN1
6 endometrial cancer 10.4
7 cervical carcinosarcoma 10.3 MAPK8IP2 MAPK8IP1
8 thrombophilia due to thrombin defect 10.3
9 ureteral obstruction 10.3
10 end stage renal failure 10.3
11 ileus 10.3
12 cervix small cell carcinoma 10.3 MAPK8IP2 MAPK8IP1
13 papillary squamous carcinoma 10.3 MAPK8IP2 MAPK8IP1
14 female urethral cancer 10.3 KLK3 ERVMER34-1
15 sigmoid disease 10.3 MAPK8IP2 MAPK8IP1
16 cervical incompetence 10.3 PTPRN MAPK8IP1
17 vaginal cancer 10.3 MAPK8IP2 MAPK8IP1
18 urinary tract obstruction 10.2
19 vaginal discharge 10.2 MAPK8IP2 MAPK8IP1
20 hypertensive encephalopathy 10.2 CABIN1 ALB
21 pyuria 10.2 KLK3 ALB
22 ovarian cancer 10.2
23 ascites, chylous 10.2
24 cervical cancer 10.2
25 hydrops, lactic acidosis, and sideroblastic anemia 10.2
26 pulmonary embolism 10.2
27 uterus carcinoma in situ 10.2 PTPRN MAPK8IP1
28 corticosteroid allergy 10.2 CABIN1 ALB
29 hemorrhoid 10.2 KLK3 ALB
30 cervix uteri carcinoma in situ 10.2 PTPRN MAPK8IP1
31 hantavirus hemorrhagic fever with renal syndrome 10.2 CABIN1 ALB
32 oxirane allergy 10.1 ERVMER34-1 ALB
33 suppressor of tumorigenicity 3 10.1
34 lymphoproliferative syndrome 10.1
35 47,xyy 10.1
36 back pain 10.1
37 radiation cystitis 10.1 MAPK8IP2 MAPK8IP1 KLK3
38 pneumocystosis 10.1 CABIN1 ALB
39 paralytic ileus 10.1 ERVMER34-1 ALB
40 pyelitis 10.1 CABIN1 ALB
41 pelvic varices 10.1 KLK3 ALB
42 isthmus cancer 10.0 PTPRN MAPK8IP2 MAPK8IP1
43 aortic aneurysm, familial abdominal, 1 10.0
44 bladder cancer 10.0
45 lipomatosis, multiple 10.0
46 microvascular complications of diabetes 3 10.0
47 microvascular complications of diabetes 4 10.0
48 microvascular complications of diabetes 6 10.0
49 microvascular complications of diabetes 7 10.0
50 scoliosis 10.0

Graphical network of the top 20 diseases related to Lymphocele:



Diseases related to Lymphocele

Symptoms & Phenotypes for Lymphocele

GenomeRNAi Phenotypes related to Lymphocele according to GeneCards Suite gene sharing:

26 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.84 MTOR
2 Decreased viability GR00173-A 9.84 MAPK8IP1
3 Decreased viability GR00221-A-1 9.84 MTOR STK10
4 Decreased viability GR00221-A-2 9.84 MAPK8IP2 STK10
5 Decreased viability GR00221-A-3 9.84 STK10
6 Decreased viability GR00221-A-4 9.84 MTOR MAPK8IP1
7 Decreased viability GR00301-A 9.84 MAPK8IP1
8 Decreased viability GR00342-S-1 9.84 MAPK8IP2 MTOR STK10
9 Decreased viability GR00342-S-2 9.84 MTOR STK10
10 Decreased viability GR00342-S-3 9.84 MAPK8IP2 STK10 MAPK8IP1
11 Decreased viability GR00402-S-2 9.84 MAPK8IP2 MTOR STK10 MAPK8IP1

Drugs & Therapeutics for Lymphocele

Drugs for Lymphocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
2
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
3 Hemostatics Phase 4
4 Coagulants Phase 4
5 Fibrinolytic Agents Phase 4
6 Anticoagulants Phase 4
7 Calcium, Dietary Phase 4
8 calcium heparin Phase 4
9
lanreotide Approved Phase 3 108736-35-2
10
Somatostatin Approved, Investigational Phase 3 51110-01-1, 38916-34-6 53481605
11
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
12 Angiopeptin Phase 3
13 Hormone Antagonists Phase 3
14 Hormones Phase 3
15 Fibrin Tissue Adhesive Phase 3
16
Pasireotide Approved Phase 2 396091-73-9 9941444
17
Octreotide Approved, Investigational 83150-76-9 6400441 383414
18 Pharmaceutical Solutions
19 Antineoplastic Agents, Hormonal

Interventional clinical trials:

(show all 37)
# Name Status NCT ID Phase Drugs
1 A Randomized Control Trial for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection Completed NCT02476357 Phase 4
2 Effect of TachoSil® on Incidence of Symptomatic and Radiographic Lymphoceles After Extended Pelvic Lymph Node Dissection in Prostate and Bladder Cancer. Completed NCT02001857 Phase 4 1 TachoSil hemostatic sponge (9,5 cm x 4,8 cm) placed on each side on the external iliac artery.
3 Does Intraoperative Application of TachoSil Reduce the Number of Lymphocele After Pelvic Lymphadenectomy? Completed NCT03752606 Phase 4
4 A Randomized Controlled Trial for PREvention of VENous ThromboEmbolism Following Radical Prostatectomy (PREVENTER Trial) Completed NCT03006562 Phase 4 Subcutaneous Heparin
5 Prevention of Pelvic Lymphocele by Floseal During Pelvic Lymphadenectomy for Gynecologic Cancer: a Pilot Study Unknown status NCT01974193 Phase 3 Floseal
6 A Collagen-Fibrin Patch (Tachosil®) for the Prevention of Symptomatic Lymphoceles After Pelvic Lymphadenectomy in Women With Gynecologic Malignancies: a Randomized Clinical Trial Completed NCT01470677 Phase 3 Tachosil fibrin patch
7 Evaluation of the Efficacity of Lanreotide LP 90 mg to Minimized the Lymphorrhea Post Axillary Lymphadenectomy in Breast Cancer Completed NCT00630695 Phase 3 Lanreotide LP 90;Placebo lanreotide
8 Efficacy of a Fibrin Sealant (Tissucol Duo®) for the Prevention of Lymphocele After Laparoscopic Pelvic Lymphadenectomy Due to Gynaecological Cancer: a Randomised Controlled Trial Completed NCT03914963 Phase 3
9 Application of the Biological Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplant Completed NCT01631448 Phase 3
10 Observation Versus Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer: A Phase 3 Prospective Multi-institutional Randomised Controlled Trial Recruiting NCT03071289 Phase 3 Cisplatin
11 Evaluation of the Effect of Pasireotide LAR Administration in the Lymphocele Prevention After Axillary Node Dissection for Breast Cancer Completed NCT01356862 Phase 2 PASIREOTIDE;PLACEBO
12 PREvention of Post-mastectomy LYMphoceles by PAdding. A Randomized Prospective Multicenter Study Unknown status NCT02894021
13 Prospective Randomized Trial on Laparoscopic Radical Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Early Stage Cervical Cancer (FIGO Stages IA2-IB1-IIA<2cm) and Advanced Stage Cervical Cancer (FIGO Stages IB2-IIA>2 Cm-IIB) Submitted to NACT With Complete Clinical Response: Thunderbeat Technology Versus Standard Bipolar Electro Surgery Unknown status NCT01717781
14 Prospective Randomized Trial on Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Endometrial Cancer FIGO Stage IB-II: Thunderbeat Technology Versus Standard Bipolar Electro-surgery. Unknown status NCT01717794
15 Assistant Lecturer of Urology in Assiut University Unknown status NCT03338140
16 THE ROLE OF FLOSEAL IN THE PREVENTION OF LYMPHOCELE AND LYMPHATIC ASCITES AFTER LYMPH NODE DISSECTION FOR GYNECOLOGIC CANCER: A RANDOMIZED CONTROLLED TRIAL Completed NCT01679483 FloSeal application
17 Prospective Open Randomized Study to Evaluate the Efficiency of Prophylactic Fenestration of the Peritoneum in Kidney Transplantation in Preventing the Occurrence of Postoperative Lymphoceles Completed NCT01206868
18 Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecological Cancer Completed NCT03765320
19 Application of Cold Plasma Energy for Reduction of Lymphoceles Following Pelvic Lymph Node Dissection During Robot-Assisted Radical Prostatectomy Completed NCT02658851
20 A Pilot Clinical Trial for the Prevention of Lymphoceles After Robotic Pelvic Lymph Node Dissections for Prostate Malignancies Using the da Vinci® EndoWrist® Oneā„¢ Vessel Sealer Completed NCT02035475
21 A Randomized Study Evaluating the Efficacy of the Synthetic Adhesive Solution Ifabond, in Reducing Seroma Formation Post Surgery in Breast Cancer Patients, When Used in Partial Mastectomy With or Without Axillary Lymph Node Dissection Completed NCT01742975
22 Routine Use of Fibrin Sealant Does Not Reduce Postoperative Wound Complications in Patients Undergoing Renal Transplantation: A Randomized Controlled Trial Completed NCT00910052
23 The Impact of Bipolar Energy Modalities on Peri-operative Outcome During Laparoscopic Staging Surgery of Gynecologic Cancers: A Randomized Clinical Trial Completed NCT02822820
24 Prevalence, Complications and Risk Factors for Lymphedema After Pelvic and Paraaortic Lymphadenectomy in Primary Radical Surgery for Early Stage Endometrial Carcinoma. Completed NCT02115477
25 Prospective Randomized Trial on2D Versus 3D Laparoscopic Radical Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Early Stage Cervical Cancer (FIGO Stages IA2-IB1-IIA<2cm) and Advanced Stage Cervical Cancer (FIGO Stages IB2-IIA>2 Cm-IIB) Submitted to NACT With Complete Clinical Response. Completed NCT02320578
26 Study to Evaluate the Efficacy of Early Detection of Lower Extremity Lymphedema After Lymphadenectomy in Gynecological Cancer and Implantation of the Protocol Completed NCT03917771
27 Prospective Randomized Trial on 2D Versus 3D Laparoscopic Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for the Treatment of Endometrial Cancer FIGO Stage IB-II Completed NCT02320565
28 Whole Body Bone Scan vs 18F-Choline PET/CT, Better Detection of Bone Metastases in Prostate Cancer Patients, PROSTAGE I Completed NCT02232685
29 Choline PET/CT vs. Dual Time Point FDG PET/CT. Better Detection of Bone and Lymph Node Metastasis in Prostate Cancer Patients, PROSTAGE II Completed NCT02232724
30 Management of Symptomatic Post-operative Lymphocele With an Patient-controlled, Vascular Catheter: A Validation Study Recruiting NCT02800980
31 The Effect of a Peritoneal Iliac Flap on Lymphocele Formation After Robotic Radical Prostatectomy Recruiting NCT03567525
32 A Prospective Observational Trial on Sentinel Lymph Node Biopsy in Patients With Early Stage Cervical Cancer Recruiting NCT02494063
33 PREventive Effect of FENestration With and Without Clipping on Post-Kidney Transplantation Lymphatic Complications: PREFEN Trial Not yet recruiting NCT03682627
34 Hemopatch to Prevent Lymphatic Leak After Robotic Prostatectomy and Pelvic Lymph Node Dissection: a Randomized Controlled Trial Not yet recruiting NCT04185922
35 Evaluation of Impact of Sandostatin® Injection Before Axillary Clearance on Lymphocele Formation In Patients With Breast Cancer Terminated NCT03791736
36 A Pilot Clinical Trial for the Prevention of Postoperative Lymphoceles Using Absorbable Micorporous Polysaccharide Hemosphere Particles During Robotic Assisted Prostatectomy With Lymph Node Dissection Terminated NCT01644136
37 Choline PET/CT vs. MeAIB PET/CT. Better Detection of Bone and Lymph Node Metastases in Prostate Cancer Patients, PROSTAGE III Withdrawn NCT02232672

Search NIH Clinical Center for Lymphocele

Cochrane evidence based reviews: lymphocele

Genetic Tests for Lymphocele

Anatomical Context for Lymphocele

MalaCards organs/tissues related to Lymphocele:

40
Kidney, Lymph Node, Prostate, Breast, Bone, Liver, Heart

Publications for Lymphocele

Articles related to Lymphocele:

(show top 50) (show all 1134)
# Title Authors PMID Year
1
Predictors of symptomatic lymphocele after kidney transplantation. 61
31486950 2019
2
Surgical strategies for lymphocele prevention in minimally-invasive radical prostatectomy and lymph-node dissection: a systematic review. 61
31797684 2019
3
[Robot-assisted kidney transplantation]. 61
31832746 2019
4
ABO-incompatible living-donor kidney transplantation: Study of 48 patients after desensitisation. 61
31208833 2019
5
Treatment of lymphocele with negative pressure wound therapy post inguinal mass excision: A case-report. 61
31790951 2019
6
A case of laparoscopic fenestration surgery for pelvic lymphocele occurring after laparoscopic radical prostatectomy. 61
31788150 2019
7
Prophylactic abdominal or retroperitoneal drain placement in major uro-oncological surgery: a systematic review and meta-analysis of comparative studies on radical prostatectomy, cystectomy and partial nephrectomy. 61
31664510 2019
8
[Diagnosis and treatment of complications related with lymph-node dissection surgery: Lymphorrea, lymphocele and lymphedema.] 61
31579044 2019
9
Indocyanine green-enhanced fluorescence-guided video-assisted axillary surgery for chronic lymphocele. 61
30549254 2019
10
Bilateral abdominopelvic lymphoceles secondary to huge uterine leiomyomas: A case report. 61
31642137 2019
11
Efficacy and Safety of Lateral Approach-Video Endoscopic Inguinal Lymphadenectomy (L-VEIL) over Open Inguinal Block Dissection: a Retrospective Study. 61
31496610 2019
12
Robotic-assisted kidney transplant: a single center experience with median follow-up of 2.8 years. 61
31489478 2019
13
Sentinel lymph node biopsy in patients with malignant melanoma: analysis of post-operative complications. 61
31368164 2019
14
Effect of Autologous Fibrin Glue on Lymphatic Drainage and Lymphocele Formation in Extended Bilateral Pelvic Lymphadenectomy in Robot-Assisted Radical Prostatectomy. 61
31187653 2019
15
Long-Term Follow-up of Immediate Latissimus Dorsi Flap Reconstruction After Neoadjuvant Chemotherapy and Radiotherapy for Invasive Breast Cancer. 61
31088723 2019
16
[Radical vulvectomy and inguinal lymphadenectomy using a single incision for the treatment of vulvar malignancy]. 61
31434426 2019
17
Full Robot-Assisted Living Donor Nephrectomy and Kidney Transplantation in a Twin Dedicated Operating Room: Initial Experience From a High-Volume Robotic Center. 61
31018770 2019
18
A Novel Technique of Dual Kidney Transplantation (DKT) From Adult Donors. 61
31051165 2019
19
Nonovarian Mimics of Ovarian Malignancy. 61
31375172 2019
20
Incidence of and risk factors for lymphocele formation after lateral pelvic lymph node dissection for rectal cancer: a retrospective study. 61
31454448 2019
21
Single cohort study: ABO-incompatible kidney transplant recipients have a higher risk of lymphocele formation. 61
31456076 2019
22
Can we predict who will need lymphocele drainage following robot assisted laparoscopic prostatectomy (RALP)? 61
31422556 2019
23
Risk factors, complications and management of lymphocele formation after radical prostatectomy: A mini-review. 61
30939628 2019
24
Risk factors for death in kidney transplant patients: analysis from a large protocol biopsy registry. 61
29860340 2019
25
Efficacy of a Fibrin Sealant (Tissucol Duo) for the Preventionof Lymphocele after Laparoscopic Pelvic Lymphadenectomy:A Randomized Controlled Trial. 61
30296475 2019
26
[Use of Vacuum-Assisted Closure Therapy in the Treatment of Postoperative Inguinal Lymphocele after Lymphadenectomy for a Vulvar Apocrine Adenocarcinoma : A Case Report]. 61
31501398 2019
27
Surgical Complications in Kidney Transplantation: An Overview of a Portuguese Reference Center. 61
31155198 2019
28
Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair. 61
31176637 2019
29
Lymphangiography and Lymphatic Embolization for the Management of Pelvic Lymphocele After Radical Prostatectomy in Prostatic Cancer. 61
30919025 2019
30
Factors Influencing Lymphocele Development After Kidney Transplant: Single Center Experience. 61
31250740 2019
31
Transposition of the left vertebral artery during endovascular stent-graft repair of the aortic arch. 61
31301891 2019
32
Sentinel node navigation surgery in cervical and endometrial cancer: a review. 61
31070770 2019
33
Comparison of clinical feasibility and oncological outcomes between video endoscopic and open inguinal lymphadenectomy for penile cancer: A systematic review and meta-analysis. 61
31145338 2019
34
Lymphatic supermicrosurgery for the treatment of recurrent lymphocele and severe lymphorrhea. 61
30767257 2019
35
Perinephric transplant fluid collection approach and management. 61
31249219 2019
36
Tissue sealants for the prevention of lymphoceles after radical inguinal lymph node dissection in patients with melanoma: A systematic review and individual patient data meta-analysis. 61
30674074 2019
37
Reduction of lymphocele rate in patients undergoing sentinel node biopsy for melanoma by intraoperative placement of plant-based hemostatic powder: Results of a prospective trial. 61
30799018 2019
38
Actinomyces odontolyticus infection 3 months post-robotic-assisted laparoscopic prostatectomy. 61
30981988 2019
39
The application of fibrin sealant for the prevention of lymphocele after lymphadenectomy in patients with gynecological malignancies: A systematic review and meta-analysis of randomized controlled trials. 61
30660344 2019
40
Development of symptomatic lymphoceles after radical prostatectomy and pelvic lymph node dissection is independent of surgical approach: a single-center analysis. 61
30796729 2019
41
Treatment of varicose veins, international consensus on which major complications to discuss with the patient: A Delphi study. 61
30012048 2019
42
Unusual lymphocele following radical cystectomy with orthotopic neobladder. 61
31000926 2019
43
The transposed femoral vein arteriovenous fistula for hemodialysis. 61
30073914 2019
44
Ultrasound characteristics of a symptomatic and asymptomatic lymphocele after pelvic and/or paraaortic lymphadenectomy. 61
30910151 2019
45
Initial experience of video endoscopic inguinal Lymphadenectomy in a center located at northeast brazilian region. 61
30676302 2019
46
Toward sutureless laparoscopic inguinal hernia repair in children? 61
30896137 2019
47
Prevention of lymphorrhea in aortic lymphadenectomy. 61
30833448 2019
48
Predictors of Lymphoceles in Women Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecologic Cancer: A Retrospective Cohort Study. 61
30875912 2019
49
Indocyanine Green as a Beacon Light in Laparoscopy: A New Application in Transplant Surgery: A Case Report. 61
30879583 2019
50
Comparison Between Bipolar Lymphatic Vessels Cautery and Suture Ligature in Prevention of Postrenal Transplant Lymphocele Formation: A Randomized Controlled Trial. 61
29697354 2019

Variations for Lymphocele

Expression for Lymphocele

Search GEO for disease gene expression data for Lymphocele.

Pathways for Lymphocele

GO Terms for Lymphocele

Biological processes related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of endocytosis GO:0045807 9.16 MAPK8IP2 MAPK8IP1
2 receptor-mediated endocytosis GO:0006898 9.13 MAPK8IP2 MAPK8IP1 ALB
3 regulation of JNK cascade GO:0046328 8.62 MAPK8IP2 MAPK8IP1

Molecular functions related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kinesin binding GO:0019894 8.96 MAPK8IP2 MAPK8IP1
2 MAP-kinase scaffold activity GO:0005078 8.62 MAPK8IP2 MAPK8IP1

Sources for Lymphocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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