Aliases & Classifications for Lymphocele

MalaCards integrated aliases for Lymphocele:

Name: Lymphocele 12 45 15 74
Lymphocele Adverse Event 74
Lymph Cyst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4347
MeSH 45 D008210
NCIt 51 C78442
SNOMED-CT 69 12167004

Summaries for Lymphocele

MalaCards based summary : Lymphocele, also known as lymphocele adverse event, is related to campomelia, cumming type and ovarian cancer. An important gene associated with Lymphocele is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways is Transcription Androgen Receptor nuclear signaling. The drugs tannic acid and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include kidney, lymph node and prostate, and related phenotype is Decreased ionizing radiation sensitivity.

Wikipedia : 77 A lymphocele is a collection of lymphatic fluid within the body not bordered by epithelial lining. It... more...

Related Diseases for Lymphocele

Graphical network of the top 20 diseases related to Lymphocele:



Diseases related to Lymphocele

Symptoms & Phenotypes for Lymphocele

GenomeRNAi Phenotypes related to Lymphocele according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased ionizing radiation sensitivity GR00232-A-1 8.92 ANKRD11 KLK3 MTOR PGC

Drugs & Therapeutics for Lymphocele

Drugs for Lymphocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved Phase 4,Phase 1,Early Phase 1 1401-55-4
2
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1 104987-11-3 6473866 445643 439492
3
Everolimus Approved Phase 4,Phase 3,Phase 1,Early Phase 1 159351-69-6 70789204 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
5
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 24280-93-1 446541
6
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Early Phase 1 53123-88-9 46835353 5284616 6436030
7
Benzocaine Approved, Investigational Phase 4,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
8
Prednisone Approved, Vet_approved Phase 4,Phase 1 53-03-2 5865
9
Methylprednisolone hemisuccinate Approved Phase 4,Phase 2,Phase 3 2921-57-5
10
Basiliximab Approved, Investigational Phase 4,Phase 3 179045-86-4, 152923-56-3
11
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 2,Phase 3 302-25-0
12
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
13
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
14
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
15
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
16
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
17
Prednisolone hemisuccinate Experimental Phase 4,Phase 2,Phase 3 2920-86-7
18 Hemostatics Phase 4,Phase 3,Not Applicable
19 Coagulants Phase 4,Phase 3,Not Applicable
20 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
21 Anesthetics Phase 4
22 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
23 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
24 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
25 Immunologic Factors Phase 4,Phase 3,Phase 1,Not Applicable,Early Phase 1
26 Antilymphocyte Serum Phase 4,Early Phase 1
27 Calcineurin Inhibitors Phase 4,Phase 3,Early Phase 1
28 Antitubercular Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
29 Thymoglobulin Phase 4,Phase 2,Phase 3,Early Phase 1
30 Antifungal Agents Phase 4,Phase 3,Phase 1,Early Phase 1
31 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
32 Antineoplastic Agents, Hormonal Phase 4,Phase 1,Not Applicable
33 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
34 Antirheumatic Agents Phase 4,Phase 3,Phase 1,Early Phase 1
35 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
36 Dermatologic Agents Phase 4,Phase 3
37 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
38 Cyclosporins Phase 4,Phase 3
39 Hormones Phase 4,Phase 3,Phase 2,Phase 1
40 Prednisolone acetate Phase 4,Phase 2,Phase 3
41 Neuroprotective Agents Phase 4,Phase 2,Phase 3
42 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
43 Methylprednisolone Acetate Phase 4,Phase 2,Phase 3
44 Protective Agents Phase 4,Phase 2,Phase 3
45 Autonomic Agents Phase 4,Phase 2,Phase 3
46 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Not Applicable
47 Antiemetics Phase 4,Phase 2,Phase 3
48 Triamcinolone hexacetonide Phase 4,Phase 3
49 Triamcinolone diacetate Phase 4,Phase 3
50 triamcinolone acetonide Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 56)
# Name Status NCT ID Phase Drugs
1 Application of Tachosil During Lymphadenectomy Completed NCT03752606 Phase 4
2 A Study for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection Completed NCT02476357 Phase 4
3 Effect of TachoSil® on Incidence of Symptomatic and Radiographic Lymphoceles After Extended Pelvic Lymph Node Dissection in Prostate and Bladder Cancer. Completed NCT02001857 Phase 4 1 TachoSil hemostatic sponge (9,5 cm x 4,8 cm) placed on each side on the external iliac artery.
4 Clinical Trial of a Silver Eluting Dressing System Completed NCT01229358 Phase 4
5 Improved Induction and Maintenance Immunosuppression in Kidney Transplantation Completed NCT00556933 Phase 4 rabbit anti-thymocyte globulin;mycophenolate mofetil;rabbit anti-thymocyte globulin;sirolimus;tacrolimus
6 Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney Transplantation Completed NCT00305396 Phase 4 Sirolimus
7 SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus Completed NCT00371826 Phase 4 Everolimus (RAD001);Cyclosporine (Calcineurin Inhibitor (CNI));Methylprednisone/prednisone;Mycophenolate sodium (MPA)
8 Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A Completed NCT02328963 Phase 4 Everolimus;mycophenolic acid
9 MMF, Daclizumab and Corticosteroids as Mainstay Immunosuppression in Renal Transplant Patients Completed NCT00231764 Phase 4 daclizumab
10 PREvention of VENous ThromboEmbolism Following Radical Prostatectomy Recruiting NCT03006562 Phase 4 Subcutaneous Heparin
11 Prospective Randomized Trial Comparing Robotic Versus Open Radical Prostatectomy Terminated NCT01365143 Phase 4
12 Prevention of Pelvic Lymphocele by Floseal During Pelvic Lymphadenectomy for Gynecologic Cancer Unknown status NCT01974193 Phase 3 Floseal
13 Efficacy of a Fibrin Sealant for the Prevention of Lymphocele After Lymphadenectomy Completed NCT03914963 Phase 3
14 Tachosil for the Prevention of Symptomatic Lymph Cysts Completed NCT01470677 Phase 3 Tachosil fibrin patch
15 Prevention of Lymphorrhea by Lanreotide in Axillary Dissection for Breast Cancer Completed NCT00630695 Phase 3 Lanreotide LP 90;Placebo lanreotide
16 Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation Completed NCT01631448 Phase 3
17 Myfortic vs. Cellcept in Kidney Transplant Recipients Completed NCT00533624 Phase 2, Phase 3 Mycophenolate Sodium Delayed Release Tablets;Mycophenolate Mofetil
18 12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients Completed NCT01843348 Phase 3 Everolimus;Tacrolimus;Cyclosporin A;Enteric Coated Mycophenolate Sodium (EC-MPS);Mycophenolate mofetil (MMF);Corticosteroids;Simulect
19 A Trial Comparing Observation With Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer Recruiting NCT03071289 Phase 3 Cisplatin
20 Surgical Complications Related to Primary or Interval Debulking in Ovarian Neoplasm Active, not recruiting NCT01461850 Phase 3 Neoadjuvant chemotherapy + Interval Debulking Surgery
21 Pasireotide LAR Administration in Lymphocele Prevention After Axillary Node Dissection for Breast Cancer Completed NCT01356862 Phase 2 PASIREOTIDE;PLACEBO
22 Neoadjuvant Chemotherapy in Epithelial Ovarian Cancer Recruiting NCT02125513 Phase 2 carboplatin and paclitaxel followed by surgery
23 Tolerance by Engaging Antigen During Cellular Homeostasis Recruiting NCT03504241 Phase 1 alemtuzumab;belatacept;sirolimus;mycophenolate mofetil;mycophenolate acid;prednisone
24 PREvention of Post-mastectomy LYMphoceles by PAdding Unknown status NCT02894021 Not Applicable
25 Thunderbeat Technology vs Standard Bipolar Electro-surgery in Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for Endometrial Cancer Unknown status NCT01717794 Not Applicable
26 Lymphedema After Primary Surgery for Endometrial Cancer Unknown status NCT02115477
27 Thunderbeat Technology vs Standard Bipolar Electro Surgery in Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy for Cervical Cancer Unknown status NCT01717781 Not Applicable
28 Cold Plasma for the Reduction of Lymphoceles Following PLND Completed NCT02658851 Not Applicable
29 Prevention of Lymphoceles After Robotic PLND Completed NCT02035475 Not Applicable
30 Prophylactic Fenestration of the Peritoneum in Kidney Transplantation Completed NCT01206868 Not Applicable
31 Efficacy Study of FloSeal for Prevention of Lymphocele After Lymphadenectomy for Gynecologic Cancer Completed NCT01679483 Not Applicable FloSeal application
32 Efficacy Study of Ifabond in Breast Cancer Surgery Completed NCT01742975 Not Applicable
33 The Comparison of Conventional and Advanced Bipolar Energy Modalities During Laparoscopic Staging Surgery of Gynecologic Cancers Completed NCT02822820 Not Applicable
34 Fibrin Sealant in Renal Transplantation Completed NCT00910052 Not Applicable
35 2D Versus 3D Radical Laparoscopic Hysterectomy for Cervical Cancer: a Prospective Randomized Trial Completed NCT02320578 Not Applicable
36 2D Versus 3D Radical Laparoscopic Hysterectomy for Endometrial Cancer: a Prospective Randomized Trial Completed NCT02320565 Not Applicable
37 Dead Space Closure With Quilting Suture Versus Conventional Closure With Drainage Completed NCT02263651 Not Applicable
38 Sentinel Lymph Node Detection in Endometrial Cancer Completed NCT02690259 Not Applicable
39 Radiofrequency Ablation vs Conventional Surgery for Superficial Venous Insufficiency Completed NCT02588911 Not Applicable
40 Open Anterograde Radical Prostatectomy Compared to Open Retrograde Technique Completed NCT02687308 Not Applicable
41 Management of Symptomatic Post-operative Lymphocele Recruiting NCT02800980
42 Peritoneal Iliac Flap and Lymphocele Formation After Robotic Radical Prostatectomy Recruiting NCT03567525 Not Applicable
43 Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection Recruiting NCT03765320
44 Sentinel Lymph Node Dissection (SLND) in Patients With Apparent Early Stage Endometrial Cancer Recruiting NCT02834988
45 The AbsorbaSeal Vascular Closure Device Trial Recruiting NCT03730571 Not Applicable
46 Efficacy of the Standard Treatment and Fusion Ontogenetic Surgery for Gynecologic Cancers Recruiting NCT02986568 Not Applicable Cisplatin;Cisplatin;5-fluorouracil, Cisplatin;5-fluorouracil, Cisplatin;Doxorubicin, Cisplatin
47 ADNEXMR Scoring System: Impact of an MR Scoring System on Therapeutic Strategy of Pelvic Adnexal Masses Recruiting NCT02664597 Not Applicable
48 Sentinel Lymph Node Biopsy in Patients With Early Stages Cervical Cancer Recruiting NCT02494063
49 Use of the Sentinel Node Biopsy for Early Endometrial Cancer. Recruiting NCT02545348
50 Preventive Fenestration With and Without Clipping in Kidney Transplantation Not yet recruiting NCT03682627 Not Applicable

Search NIH Clinical Center for Lymphocele

Cochrane evidence based reviews: lymphocele

Genetic Tests for Lymphocele

Anatomical Context for Lymphocele

MalaCards organs/tissues related to Lymphocele:

42
Kidney, Lymph Node, Prostate, Breast, Liver, Pancreas, Heart

Publications for Lymphocele

Articles related to Lymphocele:

(show top 50) (show all 360)
# Title Authors Year
1
Comparison Between Bipolar Lymphatic Vessels Cautery and Suture Ligature in Prevention of Postrenal Transplant Lymphocele Formation: A Randomized Controlled Trial. ( 29697354 )
2019
2
Standardized intraoperative application of an absorbable polysaccharide hemostatic powder to reduce the incidence of lymphocele after kidney transplantation - a prospective trial. ( 30099769 )
2019
3
The application of fibrin sealant for the prevention of lymphocele after lymphadenectomy in patients with gynecological malignancies: A systematic review and meta-analysis of randomized controlled trials. ( 30660344 )
2019
4
Lymphatic supermicrosurgery for the treatment of recurrent lymphocele and severe lymphorrhea. ( 30767257 )
2019
5
Reduction of lymphocele rate in patients undergoing sentinel node biopsy for melanoma by intraoperative placement of plant-based hemostatic powder: Results of a prospective trial. ( 30799018 )
2019
6
Ultrasound characteristics of a symptomatic and asymptomatic lymphocele after pelvic and/or paraaortic lymphadenectomy. ( 30910151 )
2019
7
Lymphangiography and Lymphatic Embolization for the Management of Pelvic Lymphocele After Radical Prostatectomy in Prostatic Cancer. ( 30919025 )
2019
8
Risk factors, complications and management of lymphocele formation after radical prostatectomy: A mini-review. ( 30939628 )
2019
9
Unusual lymphocele following radical cystectomy with orthotopic neobladder. ( 31000926 )
2019
10
Regarding "Incidence and risk factors of groin lymphocele formation after venoarterial extracorporeal membrane oxygenation in cardiogenic shock patients". ( 29579476 )
2018
11
Incidence and risk factors of groin lymphocele formation after venoarterial extracorporeal membrane oxygenation in cardiogenic shock patients. ( 28822659 )
2018
12
An unusual localization of seven months delayed pelvic lymphocele following radical retropubic prostatectomy: Case report and literature review. ( 29524857 )
2018
13
Transinguinal interstitial (intranodal) lymphatic embolization to treat high-output postoperative lymphocele. ( 29551619 )
2018
14
Bevacizumab Does Not Reduce the Lymphocele Rate in Advanced Ovarian Cancer After Complete Cytoreductive Surgery. ( 29599346 )
2018
15
Prospective Randomized Controlled Trial Exploring the Effect of TachoSil on Lymphocele Formation After Extended Pelvic Lymph Node Dissection in Prostate Cancer. ( 29775698 )
2018
16
Treatment of refractory groin lymphocele by surrounding supermicrosurgical lymphaticovenous anastomosis. ( 29788678 )
2018
17
Functional significance and risk factors for lymphocele formation after renal transplantation. ( 29864262 )
2018
18
Embolization-sclerotherapy of a refractory large volume post-operative pelvic lymphocele. ( 29988753 )
2018
19
The role of pelvic lymphocele in the development of early postoperative complications. ( 30212991 )
2018
20
Intranodal Glue Embolization for the Management of Postsurgical Groin Lymphocele and Lymphorrhea. ( 30217746 )
2018
21
Efficacy of a Fibrin Sealant (Tissucol Duo) for the Preventionof Lymphocele after Laparoscopic Pelvic Lymphadenectomy:A Randomized Controlled Trial. ( 30296475 )
2018
22
Abdominal Lymphocele Following Anterior Lumbar Interbody Fusion: A Case Report. ( 30510867 )
2018
23
Indocyanine green-enhanced fluorescence-guided video-assisted axillary surgery for chronic lymphocele. ( 30549254 )
2018
24
Colloid Osmotic Pressure Participates on the Post-transplant Lymphocele Pathogenesis. ( 30577216 )
2018
25
Lymphocele infection due to Peptoniphilus harei after radical prostatectomy. ( 29153289 )
2018
26
Robotic prostatectomy leading to a delayed MRSA infected lymphocele: a case report and review of the literature. ( 29344094 )
2018
27
Doxycycline sclerotherapy for post-traumatic inguinal lymphocele in a child. ( 29367372 )
2018
28
A Breast Reconstruction Using a Breast Prosthesis and Capsular Flap for a Lymphocele Patient. ( 29184742 )
2017
29
Delayed lymphocele formation following lateral lumbar interbody fusion of the spine. ( 27349755 )
2017
30
Postoperative Lymphocele Formation after Pelvic Lymph Node Dissection at the Time of Radical Prostatectomy Should Not Be Considered an Inevitable Consequence of the Approach. ( 27595375 )
2017
31
Reply from Authors re: Jens Uwe Stolzenburg, Iason Kyriazis, Evangelos Liatsikos. Postoperative Lymphocele Formation after Pelvic Lymph Node Dissection at the Time of Radical Prostatectomy Should Not Be Considered an Inevitable Consequence of the Approach. Eur Urol 2017;71:159-60: Which Lymphatic Vessels Have To Be Secured During Pelvic Lymph Node Dissection for Prostate Cancer? ( 27666998 )
2017
32
Prevention and management of lymphocele formation following kidney transplantation. ( 28011070 )
2017
33
Treatment of Post-transplant Lymphocele in Children. ( 28132852 )
2017
34
Critical appraisal of consecutive 36 cases of post renal transplant lymphocele: a proposed algorithm. ( 28138768 )
2017
35
Lymphocele after Lipoma Removal in Inner Thigh. ( 28223756 )
2017
36
Prophylaxis of lymphocele formation after kidney transplantation via peritoneal fenestration: a systematic review. ( 28295643 )
2017
37
Prevention of lymphocele by using gelatin-thrombin matrix as a tissue sealant after pelvic lymphadenectomy in patients with gynecologic cancers: a prospective randomized controlled study. ( 28382800 )
2017
38
Delayed Infection of a Lymphocele following RARP in a Patient with Nonspecific Symptoms. ( 28396817 )
2017
39
Microbiological evaluation of infected pelvic lymphocele after robotic prostatectomy: potential predictors for culture positivity and selection of the best empirical antimicrobial therapy. ( 28439680 )
2017
40
P.L.E.A.T.-Preventing Lymphocele Ensuring Absorption Transperitoneally: A Robotic Technique. ( 28554519 )
2017
41
Lymphocele Following Liposuction in the Thigh. ( 28664307 )
2017
42
Rate of Symptomatic Lymphocele Formation After Extraperitoneal vs Transperitoneal Robot-Assisted Radical Prostatectomy and Bilateral Pelvic Lymphadenectomy. ( 28741376 )
2017
43
Evaluation of sclerotherapy for the treatment of infected postoperative lymphocele. ( 28805604 )
2017
44
Nomogram predicting risk of lymphocele in gynecologic cancer patients undergoing pelvic lymph node dissection. ( 28989920 )
2017
45
Modern lymphatic dissection techniques for preventing post renal transplant lymphocele. ( 29151791 )
2017
46
A successful case of a para-aortic lymphocele treated with autologous peripheral blood injection. ( 29484065 )
2017
47
Symptomatic Lymphocele Formation After Sentinel Lymph Node Biopsy for Early Stage Cervical Cancer. ( 26260297 )
2016
48
Successful Treatment of Massive Pulmonary Embolism With Catheter-Directed Thrombolysis in a Patient With Lymphocele: A Rare Cause of Thromboembolism. ( 26381364 )
2016
49
Prospective Randomized Study to Compare Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Therapeutic Lymph Node Dissection With or Without the Use of an Ultrasonic Scalpel. ( 26714939 )
2016
50
The incidence and sequela of lymphocele formation after robot-assisted extended pelvic lymph node dissection. ( 26800257 )
2016

Variations for Lymphocele

Expression for Lymphocele

Search GEO for disease gene expression data for Lymphocele.

Pathways for Lymphocele

Pathways related to Lymphocele according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.79 KLK3 MTOR

GO Terms for Lymphocele

Biological processes related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.33 KLK3 PCSK7 PGC
2 multicellular organism growth GO:0035264 8.96 ANKRD11 MTOR
3 protein catabolic process GO:0030163 8.62 MTOR PGC

Molecular functions related to Lymphocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type peptidase activity GO:0008236 8.96 KLK3 PCSK7
2 peptidase activity GO:0008233 8.8 KLK3 PCSK7 PGC

Sources for Lymphocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....