MCID: LYM041
MIFTS: 10

Lymphocytes Absent

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Lymphocytes Absent

MalaCards integrated aliases for Lymphocytes Absent:

Name: Lymphocytes Absent 53

Classifications:



Summaries for Lymphocytes Absent

MalaCards based summary : Lymphocytes Absent is related to paroxysmal nocturnal hemoglobinuria and hemoglobinuria. An important gene associated with Lymphocytes Absent is LBR (Lamin B Receptor). The drugs Vidarabine and alemtuzumab have been mentioned in the context of this disorder. Affiliated tissues include b cells.

Related Diseases for Lymphocytes Absent

Diseases related to Lymphocytes Absent via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 paroxysmal nocturnal hemoglobinuria 9.6
2 hemoglobinuria 9.6

Symptoms & Phenotypes for Lymphocytes Absent

Drugs & Therapeutics for Lymphocytes Absent

Drugs for Lymphocytes Absent (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vidarabine Approved, Investigational Phase 2 24356-66-9 32326 21704
2
alemtuzumab Approved, Investigational Phase 2 216503-57-0
3
Fludarabine Approved Phase 2 21679-14-1, 75607-67-9 30751
4
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
5 Alkylating Agents Phase 2
6 Immunosuppressive Agents Phase 2
7 Anti-Infective Agents Phase 2
8 Antirheumatic Agents Phase 2
9 Antimetabolites Phase 2
10 Antiviral Agents Phase 2
11 Antimetabolites, Antineoplastic Phase 2
12 Antineoplastic Agents, Alkylating Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia Completed NCT00230282 Phase 2 Alemtuzumab;Fludarabine;Cytoxan

Search NIH Clinical Center for Lymphocytes Absent

Genetic Tests for Lymphocytes Absent

Anatomical Context for Lymphocytes Absent

MalaCards organs/tissues related to Lymphocytes Absent:

41
B Cells

Publications for Lymphocytes Absent

Articles related to Lymphocytes Absent:

# Title Authors Year
1
Regulation of glycoinositol phospholipid anchor assembly in human lymphocytes. Absent mannolipid synthesis in affected T and natural killer cell lines from paroxysmal nocturnal hemoglobinuria patients. ( 8454600 )
1993

Variations for Lymphocytes Absent

Expression for Lymphocytes Absent

Search GEO for disease gene expression data for Lymphocytes Absent.

Pathways for Lymphocytes Absent

GO Terms for Lymphocytes Absent

Sources for Lymphocytes Absent

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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