Lymphocytic Colitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: LYM042 MIFTS: 38	Lymphocytic Colitis Categories: Rare diseases, Gastrointestinal diseases, Immune diseases
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Aliases & Classifications for Lymphocytic Colitis

MalaCards integrated aliases for Lymphocytic Colitis:

Name: Lymphocytic Colitis ¹² ⁷⁶ ⁵³ ¹⁵

Colitis, Lymphocytic ⁴⁴ ⁷³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060184

ICD10 ³³ K52.89

MeSH ⁴⁴ D046730

NCIt ⁵⁰ C27147

SNOMED-CT ⁶⁸ 31437008

UMLS ⁷³ C0400822

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Summaries for Lymphocytic Colitis

NIH Rare Diseases : ⁵³ Lymphocytic colitis is form of microscopic colitis, a condition that is characterized by inflammation of the colon (large intestines). As the name suggests, microscopic colitis can only be diagnosed by examining a small sample of colon tissue under a microscope. In lymphocytic colitis, specifically, the tissues and lining of the colon are of normal thickness, but an increase in the number of lymphocytes (a type of white blood cell) is observed. Signs and symptoms of the condition may include chronic, watery diarrhea; abdominal pain, cramping, and bloating; weight loss; nausea; dehydration; and/or fecal incontinence. The underlying cause of lymphocytic colitis is currently unknown; however, scientists suspect that autoimmune conditions, medications, infections, genetic factors, and/or bile acid malabsorption may contribute to the development of the condition. Treatment is based on the signs and symptoms present in each person and may include certain medications, dietary modifications, and in rare cases, surgery.

MalaCards based summary : Lymphocytic Colitis, also known as colitis, lymphocytic, is related to collagenous colitis and microscopic colitis. An important gene associated with Lymphocytic Colitis is CHGA (Chromogranin A), and among its related pathways/superpathways is Celecoxib Pathway, Pharmacodynamics. The drugs Budesonide and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include colon, endothelial and monocytes, and related phenotype is homeostasis/metabolism.

Disease Ontology : ¹² A colitis characterized by an accumulation of lymphocytes in the colonic epithelium and connective tissue (lamina propria).

Wikipedia : ⁷⁶ Lymphocytic colitis is a subtype of microscopic colitis, a condition characterized by chronic non-bloody... more...

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Related Diseases for Lymphocytic Colitis

Diseases related to Lymphocytic Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)

#	Related Disease	Score	Top Affiliating Genes
1	collagenous colitis	32.3	CD79A CHGA
2	microscopic colitis	32.3	ATP12A CD79A
3	duodenitis	28.9	ATP12A ATP4A CD79A
4	peritoneal serous adenocarcinoma	10.7	CHGA PTGER4
5	auditory system cancer	10.6	CHGA MMP9
6	colitis	10.6
7	carcinoid syndrome	10.5	CHGA PYY
8	chronic follicular conjunctivitis	10.4	CD79A MMP9
9	blepharochalasis	10.4	CD79A MMP9
10	fungal esophagitis	10.3	ATP12A ATP4A
11	bladder calculus	10.3	ATP12A ATP4A
12	neonatal candidiasis	10.3	ATP12A ATP4A
13	photoallergic dermatitis	10.3	ATP12A ATP4A
14	squamous papillomatosis	10.3	ATP12A ATP4A
15	acute laryngitis	10.3	ATP12A ATP4A
16	gastroduodenal crohn's disease	10.3	ATP12A ATP4A
17	toxic megacolon	10.3	ATP12A ATP4A
18	aspiration pneumonitis	10.3	ATP12A ATP4A
19	postsurgical hypothyroidism	10.3	ATP12A ATP4A
20	gastric antral vascular ectasia	10.3	ATP12A ATP4A
21	parotitis	10.3	CD79A MMP9
22	esophageal candidiasis	10.3	ATP12A ATP4A
23	rumination disorder	10.3	ATP12A ATP4A
24	bile reflux	10.3	ATP12A ATP4A
25	granulomatous gastritis	10.3	ATP12A ATP4A
26	active peptic ulcer disease	10.3	ATP12A ATP4A
27	laryngeal disease	10.3	ATP12A ATP4A
28	ischemic neuropathy	10.3	ATP12A ATP4A
29	capillary disease	10.3	ATP12A ATP4A
30	peptic esophagitis	10.3	ATP12A ATP4A
31	duodenal disease	10.3	ATP12A ATP4A
32	dyskinesia of esophagus	10.3	ATP12A ATP4A
33	serotonin syndrome	10.3	CHGA PYY
34	hernia, hiatus	10.3	ATP12A ATP4A
35	congenital disorder of deglycosylation	10.3	ATP12A ATP4A
36	anismus	10.3	ATP12A ATP4A
37	esophageal atresia/tracheoesophageal fistula	10.3	ATP12A ATP4A
38	laryngitis	10.3	ATP12A ATP4A
39	laryngeal tuberculosis	10.3	ATP12A ATP4A
40	clostridium difficile colitis	10.3	ATP12A ATP4A
41	lower urinary tract calculus	10.2	ATP12A ATP4A
42	aspiration pneumonia	10.2	ATP12A ATP4A
43	diarrhea 1, secretory chloride, congenital	10.2	ATP12A ATP4A
44	chronic laryngitis	10.2	ATP12A ATP4A
45	chronic intestinal vascular insufficiency	10.2	ATP12A ATP4A
46	eosinophilic gastritis	10.2	ATP12A ATP4A
47	polyposis, skin pigmentation, alopecia, and fingernail changes	10.2	ATP12A ATP4A
48	esophageal varix	10.2	ATP12A ATP4A
49	esophagus adenocarcinoma	10.2	ATP12A ATP4A
50	myopathy, x-linked, with excessive autophagy	10.2	ATP12A ATP4A

Graphical network of the top 20 diseases related to Lymphocytic Colitis:

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Symptoms & Phenotypes for Lymphocytic Colitis

MGI Mouse Phenotypes related to Lymphocytic Colitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.23	ATP12A ATP4A CD79A CHGA IRAK2 MMP9

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Drugs & Therapeutics for Lymphocytic Colitis

Drugs for Lymphocytic Colitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Budesonide

Approved

Phase 3,Phase 2,Not Applicable

51333-22-3

63006 5281004

Synonyms:

(11b,16a)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11β,16α)-16,17-(butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde

(RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde

(S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione

16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione

16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione

16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione

16alpha-,17alpha--butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione

51333-22-3

AC1L1DQE

AC1L1Y6Y

AC1L22VC

AC1MHWI7

AC-4697

B 7777

B7777_SIGMA

Bidien

Bio-0010

BPBio1_000523

BRD-A34299591-001-03-4

BRD-A82238138-001-01-7

BSPBio_000475

BSPBio_002160

Budecort Inhaler

Budenofalk

Budeson

budesonide

Budesonide (JAN/USAN/INN)

Budesonide [USAN:INN:BAN:JAN]

Budesonide Easyhaler

Budesonide MMX

Budesonide, (R)-isomer

Budesonide, (S)-isomer

Budesonido

Budesonido [INN-Spanish]

Budesonidum

Budesonidum [INN-Latin]

Budiair

Budicort

C25H34O6

CCRIS 5230

CHEBI:3207

CHEBI:656601

CHEMBL1370

CID2462

CID3033890

CID40000

CID5281004

CID63006

Cortivent

CPD000058337

D00246

DB01222

Desowen

Dexbudesonide

Dexbudesonide [INN]

DivK1c_000475

EINECS 257-139-7

EINECS 257-160-1

EINECS 257-161-7

Entocort

Entocort EC

Entocort EC (TN)

EU-0100174

Giona Easyhaler

HMS1569H17

HMS1921I22

HMS2094I13

HMS501H17

Horacort

IDI1_000475

Inflammide

KBio1_000475

KBio3_001660

KBioGR_001361

Lopac0_000174

LS-187734

LS-7235

MAP-0010

Micronyl

Miflonide

MLS000028507

MLS001077323

MLS002207112

MolPort-002-529-265

MolPort-003-666-332

MolPort-003-986-909

NCGC00015165-03

NCGC00021318-03

NCGC00021318-06

NCGC00089747-02

NCGC00089747-03

NCGC00089747-04

NCGC00178789-01

NINDS_000475

Noex

Preferid

Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

Prestwick_840

Prestwick0_000518

Prestwick1_000518

Prestwick2_000518

Prestwick3_000518

Pulmaxan

Pulmaxan turbohaler

Pulmicort

Pulmicort (TN)

Pulmicort Flexhaler

Pulmicort Nebuamp

Pulmicort Respules

Pulmicort Topinasal

Pulmicort turbuhaler

Pulmicort Turbuhaler

Respules

Rhinocort

Rhinocort alpha

Rhinocort Aqua

Rhinocort Turbuhaler

Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide

Rhinosol

S 1320

S1286_Selleck

S-1320

SAM002699898

SMR000058337

SPBio_000586

SPBio_002396

SPECTRUM1500813

Spectrum2_000623

Spectrum3_000620

Spectrum4_000821

Spectrum5_001738

Spirocort

ST51039033

TL8003397

Tridesilon

UDB

UNII-168L5HT37P

UNII-2HI1006KPH

UNII-Q3OKS62Q6X

Unit dose budesonide

ZINC03938751

ZINC04097286

Analgesics

Phase 3

Analgesics, Non-Narcotic

Phase 3

Anti-Asthmatic Agents

Phase 3,Phase 2,Not Applicable

Anti-Inflammatory Agents

Phase 3,Phase 2,Not Applicable

Anti-Inflammatory Agents, Non-Steroidal

Phase 3

Antirheumatic Agents

Phase 3

Autonomic Agents

Phase 3,Phase 2,Not Applicable

Bronchodilator Agents

Phase 3,Phase 2,Not Applicable

glucocorticoids

Phase 3,Phase 2,Not Applicable

Hormone Antagonists

Phase 3,Phase 2,Not Applicable

Hormones

Phase 3,Phase 2,Not Applicable

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 3,Phase 2,Not Applicable

Mesalamine

Phase 3

89-57-6

Peripheral Nervous System Agents

Phase 3,Phase 2,Not Applicable

Respiratory System Agents

Phase 3,Phase 2,Not Applicable

Pharmaceutical Solutions

Not Applicable

Antacids

Not Applicable

Anti-Ulcer Agents

Not Applicable

Bismuth

Not Applicable

7440-69-9

16682734 105143

Synonyms:

17034_FLUKA

24267-48-9

25243-76-9

264008_ALDRICH

265462_ALDRICH

265470_ALDRICH

452386_ALDRICH

556130_ALDRICH

7440-69-9

83Bi

95372_ALDRICH

95372_FLUKA

95375_FLUKA

AC1NSDYX

AC1O4PN8

AR-1I0647

Bi(3+)

Bismut

bismuth

Bismuth standard for AAS

Bismuth standard for ICP

Bismuth(III) cation

Bismuth(III) nitrate solution

BISMUTH, 99.95%

BISMUTH, 99.999%

Bismuth, elemental

Bismuth-209

bismuto

Bisumth(3+) ion

C15471

CHEBI:33301

CID5359367

EINECS 231-177-4

HSDB 2078

LS-44708

LTBB002773

MolPort-003-925-759

Wismut

Gastrointestinal Agents

Not Applicable

Cola

Nutraceutical

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Budesonide Versus Mesalazine Versus Placebo in Lymphocytic Colitis	Completed	NCT01209208	Phase 3	Budesonide;Mesalamine
2	Budesonide Treatment for Lymphocytic Colitis	Completed	NCT00180050	Phase 3	Budesonide
3	Budesonide Versus Placebo for the Treatment of Lymphocytic Colitis	Terminated	NCT00217022	Phase 2, Phase 3	Budesonide
4	Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis	Unknown status	NCT01504048	Not Applicable
5	Case-Control Study to Identify Risk Factors for Microscopic Colitis	Completed	NCT01928667
6	Treatment of Microscopic Colitis	Terminated	NCT00184171	Not Applicable	Budesonide;Bismuth;Fiber

Search NIH Clinical Center for Lymphocytic Colitis

Cochrane evidence based reviews: colitis, lymphocytic

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Genetic Tests for Lymphocytic Colitis

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Anatomical Context for Lymphocytic Colitis

MalaCards organs/tissues related to Lymphocytic Colitis:

⁴¹

Colon, Endothelial, Monocytes, Small Intestine

Sources

Publications for Lymphocytic Colitis

Articles related to Lymphocytic Colitis:

(show top 50) (show all 118)

#	Title	Authors	Year
1	Lymphocytic Colitis: Pathologic predictors of response to therapy. ( 29452215 )	Setia N....Lauwers G.Y.	2018
2	Evaluation of Melatonin Secretion and Metabolism Exponents in Patients with Ulcerative and Lymphocytic Colitis. ( 29382152 )	Chojnacki C....PopA8awski T.	2018
3	Atypical Colonoscopic Presentation of Lymphocytic Colitis Mimicking Hyperplastic Polyposis Syndrome. ( 29637040 )	Iqbal U....Quadri A.A.	2018
4	Microscopic Colitis: A Review of Collagenous and Lymphocytic Colitis. ( 29230146 )	Boland K....Nguyen G.C.	2017
5	Epithelial barrier dysfunction in lymphocytic colitis through cytokine-dependent internalization of claudin-5 and -8. ( 28138755 )	Barmeyer C....Schulzke J.D.	2017
6	Interventions for treating lymphocytic colitis. ( 28702956 )	Chande N....MacDonald J.K.	2017
7	Bullous Pemphigoid with Lymphocytic Colitis: A Case Report and Short Literature Review. ( 27469343 )	Sperl A....Meyersburg D.	2016
8	CD3 immunohistochemical staining in diagnosis of lymphocytic colitis. ( 26772395 )	Fiehn A.M....Engel P.J.	2016
9	HLA Associations Distinguish Collagenous From Lymphocytic Colitis. ( 27481432 )	Westerlind H....D'Amato M.	2016
10	Microscopic colitis: a descriptive clinical cohort study of 795 patients with collagenous and lymphocytic colitis. ( 26679722 )	Mellander M.R....BjAPrk J.	2016
11	Cat Scratch Colon in a Patient With Lymphocytic Colitis. ( 27580771 )	Song J.S....Han D.S.	2016
12	ENaC Dysregulation Through Activation of MEK1/2 Contributes to Impaired Na+ Absorption in Lymphocytic Colitis. ( 26658215 )	Barmeyer C....Schulzke J.D.	2016
13	Lymphocytic colitis complicated by a mass in the terminal ileum. ( 26034326 )	Hui C.K.	2015
14	Clinical characteristics and patterns and predictors of response to therapy in collagenous and lymphocytic colitis. ( 25997458 )	Colussi D....Khalili H.	2015
15	Increased Production of Lysozyme Associated with Bacterial Proliferation in Barrett's Esophagitis, Chronic Gastritis, Gluten-induced Atrophic Duodenitis (Celiac Disease), Lymphocytic Colitis, Collagenous Colitis, Ulcerative Colitis and Crohn's Colitis. ( 26637845 )	Rubio C.A.	2015
16	Association of lymphocytic colitis and lactase deficiency in pediatric population. ( 25523228 )	Sun J....Fan R.	2015
17	Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings? ( 25167800 )	Park H.S....Yoo K.S.	2014
18	Clinical presentation, diagnosis, pathogenesis and treatment options for lymphocytic colitis (Review). ( 23695201 )	El-Salhy M....Hausken T.	2013
19	Macroscopic Findings in Lymphocytic Colitis. ( 24211291 )	Aggarwal A....Helper D.	2013
20	Lymphocytic colitis is associated with increased pro-inflammatory cytokine profile and up regulation of prostaglandin receptor EP4. ( 23613969 )	Dey I....Chadee K.	2013
21	Stable incidence of collagenous colitis and lymphocytic colitis in A9rebro, Sweden, 1999-2008: a continuous epidemiologic study. ( 23945183 )	Wickbom A....Tysk C.	2013
22	Cryptosporidiosis-associated lymphocytic colitis. ( 23912411 )	Weinstock L.B....Gutwein M.B.	2013
23	In vivo diagnosis of lymphocytic colitis by confocal laser endomicroscopy. ( 22851663 )	Neumann H....Neurath M.F.	2013
24	Lymphocytic colitis secondary to ipilimumab treatment. ( 22114048 )	GarcA-a-Varona A....Makrauer F.	2013
25	High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis. ( 23155335 )	El-Salhy M....Hausken T.	2012
26	Systematic review: are lymphocytic colitis and collagenous colitis two subtypes of the same disease - microscopic colitis? ( 22670660 )	Rasmussen M.A....Munck L.K.	2012
27	Lymphocytic colitis and collagenous colitis: a review of clinicopathologic features and immunologic abnormalities. ( 22156832 )	Mahajan D....Liu X.	2012
28	Letter: are lymphocytic colitis and collagenous colitis really the same disease? ( 22913854 )	FernA!ndez-BaA+ares F....Gisbert J.P.	2012
29	Are collagenous and lymphocytic colitis different aspects of the same disease? ( 23016916 )	Vigren L....SjAPberg K.	2012
30	Duloxetine-induced lymphocytic colitis. ( 22874808 )	Gwillim E.C....Bowyer B.A.	2012
31	The behavior of matrix metalloproteinase-9 in lymphocytic colitis, collagenous colitis and ulcerative colitis. ( 21678108 )	Lakatos G....HerszAcnyi L.	2012
32	Chromogranin A cell density as a diagnostic marker for lymphocytic colitis. ( 22699394 )	El-Salhy M....Hausken T.	2012
33	The various faces of autoimmune endocrinopathies: non-tumoral hypergastrinemia in a patient with lymphocytic colitis and chronic autoimmune gastritis. ( 23043903 )	Melcescu E....Koch C.A.	2012
34	MPA: a treatment option for lymphocytic colitis and mesalamine-induced interstitial nephritis. ( 22147390 )	Halbritter J....Rasche F.M.	2012
35	Cardiac arrest due to lymphocytic colitis: a case report. ( 22405093 )	Groth K.A....fgren B.	2012
36	Evolution of the incidence of collagenous colitis and lymphocytic colitis in Terrassa, Spain: a population-based study. ( 20878755 )	FernA!ndez-BaA+ares F....Viver J.M.	2011
37	High chromogranin A cell density in the colon of patients with lymphocytic colitis. ( 21584496 )	El-Salhy M....Gundersen T.D.	2011
38	Unique endoscopic findings in lymphocytic colitis. ( 22305502 )	Koulaouzidis A.	2011
39	Pediatric lymphocytic colitis presenting with intractable diarrhea. ( 21543998 )	Kuhn B.R....Mezoff A.G.	2011
40	Lymphocytic colitis presenting as difficult diarrhoea in an African woman: a case report and review of the literature. ( 20205879 )	Ekrikpo U.E....Oluwasola A.O.	2010
41	Differences in the T-bet and GATA-3 expression patterns between lymphocytic colitis and coeliac disease. ( 20809338 )	JAPhrens K....Anagnostopoulos I.	2010
42	A retrospective study on a cohort of patients with lymphocytic colitis. ( 20575599 )	Simondi D....Astegiano M.	2010
43	Lymphocytic colitis in Satoyoshi syndrome. ( 20710153 )	Ishii K....Morishita Y.	2010
44	Lymphocytic colitis under treatment with duloxetine. ( 20517807 )	Kusnik B....Stolte M.	2010
45	Enterocolic lymphocytic phlebitis and lymphocytic colitis: drug-related coexistent pathology. ( 18758788 )	Jain R....Chetty R.	2009
46	Large intestine: Remission of lymphocytic colitis with budesonide. ( 19713982 )	Tysk C.	2009
47	Collagenous and lymphocytic colitis: systematic review and update of the literature. ( 20203510 )	Temmerman F....Baert F.	2009
48	Paucicellular lymphocytic colitis: is it a minor form of lymphocytic colitis? A clinical pathological and immunological study. ( 19352342 )	FernA!ndez-BaA+ares F....Viver J.M.	2009
49	Budesonide is effective in treating lymphocytic colitis: a randomized double-blind placebo-controlled study. ( 19303012 )	Miehlke S....Stolte M.	2009
50	Nodular lymphoid hyperplasia and histologic changes mimicking celiac disease, collagenous sprue, and lymphocytic colitis in a patient with selective IgA deficiency. ( 19286327 )	Joo M....Kim N.H.	2009

Sources

Genes for Lymphocytic Colitis

Genes related to Lymphocytic Colitis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CHGA	Chromogranin A	Protein Coding	21.13	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	PYY	Peptide YY	Protein Coding	20.49	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	PTGER4	Prostaglandin E Receptor 4	Protein Coding	19.58	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	MMP9	Matrix Metallopeptidase 9	Protein Coding	16.43	GeneCards inferred via : Publications (show sections)
5	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	15.72	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	15.71	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	MAGI3	Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 3	Protein Coding	15.09	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	IRAK2	Interleukin 1 Receptor Associated Kinase 2	Protein Coding	14.97	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	CD79A	CD79a Molecule	Protein Coding	14.96	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Lymphocytic Colitis

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Expression for Lymphocytic Colitis

Search GEO for disease gene expression data for Lymphocytic Colitis.

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Pathways for Lymphocytic Colitis

Pathways related to Lymphocytic Colitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Celecoxib Pathway, Pharmacodynamics ⁶¹	10.39	MMP9 PTGER4

Sources

GO Terms for Lymphocytic Colitis

Biological processes related to Lymphocytic Colitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	JNK cascade	GO:0007254	9.4	IRAK2 PTGER4
2	potassium ion import	GO:0010107	9.37	ATP12A ATP4A
3	ATP hydrolysis coupled proton transport	GO:0015991	9.32	ATP12A ATP4A
4	cellular sodium ion homeostasis	GO:0006883	9.26	ATP12A ATP4A
5	cellular potassium ion homeostasis	GO:0030007	9.16	ATP12A ATP4A
6	sodium ion export across plasma membrane	GO:0036376	8.96	ATP12A ATP4A
7	establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	8.62	ATP12A ATP4A

Molecular functions related to Lymphocytic Colitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sodium:potassium-exchanging ATPase activity	GO:0005391	8.96	ATP12A ATP4A
2	potassium:proton exchanging ATPase activity	GO:0008900	8.62	ATP12A ATP4A

Sources

Sources for Lymphocytic Colitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

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⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

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⁵¹ NDF-RT

⁵² NIH Clinical Center

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⁵⁶ Novus Biologicals

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⁵⁸ OMIM via Orphanet

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⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

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⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

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⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia