MCID: LYM015
MIFTS: 29

Lymphocytic Gastritis

Categories: Gastrointestinal diseases, Immune diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Lymphocytic Gastritis

MalaCards integrated aliases for Lymphocytic Gastritis:

Name: Lymphocytic Gastritis 11 14 71 33

Classifications:



External Ids:

Disease Ontology 11 DOID:4035
NCIt 49 C27051
SNOMED-CT 68 235658000
ICD11 33 2052188597
UMLS 71 C1283271

Summaries for Lymphocytic Gastritis

MalaCards based summary: Lymphocytic Gastritis is related to gastric lymphoma and lymphoma, mucosa-associated lymphoid type. An important gene associated with Lymphocytic Gastritis is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit). The drugs Esomeprazole and Anti-Ulcer Agents have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, t cells and pancreas, and related phenotype is mortality/aging.

Related Diseases for Lymphocytic Gastritis

Diseases related to Lymphocytic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 244)
# Related Disease Score Top Affiliating Genes
1 gastric lymphoma 30.4 ATP4A ATP12A
2 lymphoma, mucosa-associated lymphoid type 30.3 GAST ATP4A ATP12A
3 gastritis, familial giant hypertrophic 30.1 GAST ATP4A ATP12A
4 peptic ulcer disease 30.1 GAST ATP4A ATP12A
5 exanthem 29.8 CD8A ATP12A
6 gastric ulcer 29.8 GAST ATP12A
7 bile reflux 29.7 GAST ATP4A ATP12A
8 vitamin b12 deficiency 29.7 GAST ATP4A ATP12A
9 microinvasive gastric cancer 29.7 GAST ATP4A ATP12A
10 atrophic gastritis 29.7 GAST ATP4A ATP12A
11 gastroesophageal reflux 29.6 GAST ATP4A ATP12A
12 lymphocytic colitis 29.5 TOR1A TGM2 CD8A ATP4A ATP12A
13 collagenous colitis 29.5 TOR1A TGM2 CD8A ATP4A ATP12A
14 microscopic colitis 29.5 TOR1A TGM2 CD8A ATP4A ATP12A
15 deficiency anemia 29.5 TOR1A GAST CD8A ATP4A ATP12A
16 autoimmune gastritis 29.4 GAST CD8A ATP4A ATP12A
17 celiac disease 1 29.2 TOR1A TIA1 TGM2 IL15 GAST CD8A
18 duodenitis 28.8 TOR1A TGM2 GAST CD8A ATP4A ATP12A
19 collagenous gastritis 11.2
20 gastritis 10.9
21 helicobacter pylori infection 10.6
22 chronic erosive gastritis 10.5
23 stomach disease 10.4
24 pancreatic vasoactive intestinal peptide producing tumor 10.3 ATP4A ATP12A
25 acquired laryngomalacia 10.3 ATP4A ATP12A
26 laryngomalacia 10.3 ATP4A ATP12A
27 scalp dermatosis 10.3 ATP4A ATP12A
28 acquired gastric outlet stenosis 10.3 ATP4A ATP12A
29 lingual goiter 10.3 ATP4A ATP12A
30 esophageal diverticulosis 10.3 ATP4A ATP12A
31 benign shuddering attacks 10.3 ATP4A ATP12A
32 persistent moderate asthma 10.3 ATP4A ATP12A
33 viral esophagitis 10.3 ATP4A ATP12A
34 cervix erosion 10.3 ATP4A ATP12A
35 bacterial esophagitis 10.3 ATP4A ATP12A
36 chronic duodenal ileus 10.3 ATP4A ATP12A
37 angiodysplasia of intestine 10.3 ATP4A ATP12A
38 angiodysplasia 10.3 ATP4A ATP12A
39 benzylpenicillin allergy 10.3 ATP4A ATP12A
40 penicillin allergy 10.3 ATP4A ATP12A
41 fungal esophagitis 10.3 ATP4A ATP12A
42 esophagus melanoma 10.3 ATP4A ATP12A
43 emphysematous cholecystitis 10.3 ATP4A ATP12A
44 afferent loop syndrome 10.3 ATP4A ATP12A
45 laryngeal tuberculosis 10.3 ATP4A ATP12A
46 gastrojejunal ulcer 10.3 ATP4A ATP12A
47 cefuroxime allergy 10.3 ATP4A ATP12A
48 median arcuate ligament syndrome 10.3 ATP4A ATP12A
49 bacterial gastritis 10.3 ATP4A ATP12A
50 pneumatosis cystoides intestinalis 10.3 ATP4A ATP12A

Graphical network of the top 20 diseases related to Lymphocytic Gastritis:



Diseases related to Lymphocytic Gastritis

Symptoms & Phenotypes for Lymphocytic Gastritis

MGI Mouse Phenotypes related to Lymphocytic Gastritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.23 ATP4A B3GAT1 CD8A GAST IL15 TGM2

Drugs & Therapeutics for Lymphocytic Gastritis

Drugs for Lymphocytic Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Esomeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6, 119141-88-7 9568614 4594
2 Anti-Ulcer Agents Phase 3
3 Antacids Phase 3
4 Proton Pump Inhibitors Phase 3
5 Gastrointestinal Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Double-Blind, Randomized, Placebo-Controlled Multicenter Trial on the Efficacy of Esomeprazole Treatment for Patients With Lymphocytic Gastritis Unknown status NCT00455754 Phase 3 Esomeprazole

Search NIH Clinical Center for Lymphocytic Gastritis

Genetic Tests for Lymphocytic Gastritis

Anatomical Context for Lymphocytic Gastritis

Organs/tissues related to Lymphocytic Gastritis:

MalaCards : Salivary Gland, T Cells, Pancreas, Liver

Publications for Lymphocytic Gastritis

Articles related to Lymphocytic Gastritis:

(show top 50) (show all 201)
# Title Authors PMID Year
1
Pan-Gastrointestinal Tract Mucosal Pathologies in Patients with Celiac Disease with the Demonstration of IgA Anti-Transglutaminase Mucosal Deposits: A Case-Control Study. 62
34499270 2022
2
Varioliform-type lymphocytic gastritis: Treating H. pylori or (rather) something else? 62
35427586 2022
3
Helicobacter pylori-negative Chronic Gastritis in Children: A Systematic Review. 62
35175996 2022
4
Lymphocytic gastritis and its relationships with other gastrointestinal disorders. 62
34587312 2021
5
Editorial: lymphocytic gastritis and its relationships with other gastrointestinal disorders. 62
34699097 2021
6
Editorial: lymphocytic gastritis and its relationships with other gastrointestinal disorders-authors' reply. 62
34699096 2021
7
Clinical and gastro-duodenal histopathological features of enteropathy due to angiotensin II receptor blockers. 62
34330666 2021
8
Collagenous gastritis: Epidemiology and clinical associations. 62
33824091 2021
9
Severe spruelike enteropathy and collagenous colitis caused by olmesartan. 62
34556042 2021
10
Pathologic Manifestations of Gastrointestinal and Hepatobiliary Injury in Immune Checkpoint Inhibitor Therapy. 62
32338534 2021
11
Incidental Finding of Lymphocytic Gastritis After an Upper Gastrointestinal Bleed. 62
32059921 2021
12
EOSINOPHILIC GASTRITIS IN CHILDREN: MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL DIAGNOSTIC CRITERIA. 62
34459778 2021
13
Lymphocytic gastritis and celiac disease. 62
34060292 2021
14
Topography, morphology, and etiology of lymphocytic gastritis: a focus on celiac disease. 62
32474731 2020
15
Topography, morphology, and etiology of lymphocytic gastritis: a focus on celiac disease. 62
32367267 2020
16
Auto-immune gastritis induced by pembrolizumab, an anti-PD-1, in a melanoma patient. 62
33094598 2020
17
The Dysfunctional Immune System in Common Variable Immunodeficiency Increases the Susceptibility to Gastric Cancer. 62
32575504 2020
18
The coeliac stomach: A review of the literature. 62
32295740 2020
19
Topography, morphology, and etiology of lymphocytic gastritis: a single institution experience. 62
31897816 2020
20
Lymphocytic Gastritis Overshadowed by Gastric Mucosa-Associated Lymphoid Tissue Lymphoma. 62
30773956 2019
21
Lymphocytic gastritis in a patient with dyspepsia. 62
31534752 2019
22
Immune-related acute and lymphocytic gastritis in a patient with metastatic melanoma treated with pembrolizumab immunotherapy. 62
31748755 2019
23
Lymphocytic gastritis. 62
31820858 2019
24
Non-malignant Helicobacter pylori-Associated Diseases. 62
31016630 2019
25
Lymphocytic gastritis induced by pembrolizumab in a patient with metastatic melanoma. 62
30256271 2018
26
Associations of Microscopic Colitis With Other Lymphocytic Disorders of the Gastrointestinal Tract. 62
29535059 2018
27
The differential diagnosis of Helicobacter pylori negative gastritis. 62
30255340 2018
28
Subtypes of chronic gastritis in patients with celiac disease before and after gluten-free diet. 62
29026594 2017
29
Recurrent anaemia in a patient with lymphocytic gastritis and vitamin B12 deficiency. 62
28943131 2017
30
Rare Gastric Lesions Associated with Helicobacter pylori Infection: A Histopathological Review. 62
28592787 2017
31
Transverse Myelitis as Manifestation of Celiac Disease in a Toddler. 62
28153851 2017
32
Development of lymphocytic gastritis with recurrent Helicobacter pylori infection. 62
28211221 2017
33
Lymphocytic Gastritis Identified by Abnormal PET Scan. 62
28462239 2017
34
Propionibacterium acnes overabundance and natural killer group 2 member D system activation in corpus-dominant lymphocytic gastritis. 62
27538697 2016
35
The pathological findings seen in laparoscopic sleeve gastrectomies for weight loss. 62
27020497 2016
36
Pathological and Clinical Correlation between Celiac Disease and Helicobacter Pylori Infection; a Review of Controversial Reports. 62
27252814 2016
37
Lymphocytic gastritis: clinical, endoscopic and histopathologic features. 62
27532536 2016
38
Letter: lymphocytic gastritis and coeliac disease. 62
26331558 2015
39
Letter: lymphocytic gastritis and coeliac disease - authors' reply. 62
26331559 2015
40
The coeliac stomach: gastritis in patients with coeliac disease. 62
25973720 2015
41
Collagenous gastritis: a morphologic and immunohistochemical study of 40 patients. 62
25234289 2015
42
Lymphocytic gastritis is not associated with active Helicobacter pylori infection. 62
24826984 2014
43
Gastric adenocarcinoma in common variable immunodeficiency: features of cancer and associated gastritis may be characteristic of the condition. 62
24788529 2014
44
Helicobacter pylori Associated Lymphocytic Gastritis in a Child. 62
25349835 2014
45
Lymphocytic gastritis showing concomitant occurrence of both CD4 + and CD8 + T-cells among epithelial cells. 62
25047508 2014
46
Pathology and differential diagnosis of chronic, noninfectious gastritis. 62
24815937 2014
47
High proportion of granzyme B+ intraepithelial lymphocytes contributes to epithelial apoptosis in Helicobacter pylori-associated lymphocytic gastritis. 62
23356909 2013
48
Iron deficiency anemia due to lymphocytic gastritis with Helicobacter pylori infection in childhood: case report. 62
23528908 2013
49
Endoscopic, ultrasonographic, and pathologic correlation of lymphocytic gastritis. 62
23716104 2013
50
Endoscopic and histological gastric lesions in children with celiac disease: mucosal involvement is not only confined to the duodenum. 62
22773062 2012

Variations for Lymphocytic Gastritis

Expression for Lymphocytic Gastritis

Search GEO for disease gene expression data for Lymphocytic Gastritis.

Pathways for Lymphocytic Gastritis

GO Terms for Lymphocytic Gastritis

Biological processes related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular sodium ion homeostasis GO:0006883 9.56 ATP4A ATP12A
2 sodium ion export across plasma membrane GO:0036376 9.46 ATP4A ATP12A
3 cellular potassium ion homeostasis GO:0030007 9.26 ATP4A ATP12A
4 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.92 ATP4A ATP12A

Molecular functions related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 9.56 ATP4A ATP12A
2 P-type sodium:potassium-exchanging transporter activity GO:0005391 9.46 ATP4A ATP12A
3 P-type potassium transmembrane transporter activity GO:0008556 8.96 ATP4A ATP12A
4 P-type potassium:proton transporter activity GO:0008900 8.92 ATP4A ATP12A

Sources for Lymphocytic Gastritis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....