Lymphocytic Gastritis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: LYM015 MIFTS: 32	Lymphocytic Gastritis Categories: Gastrointestinal diseases, Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

Sources

Aliases & Classifications for Lymphocytic Gastritis

MalaCards integrated aliases for Lymphocytic Gastritis:

Name: Lymphocytic Gastritis ¹² ¹⁵ ⁷²

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4035

NCIt ⁵⁰ C27051

UMLS ⁷² C1283271

Sources

Summaries for Lymphocytic Gastritis

MalaCards based summary : Lymphocytic Gastritis is related to acute graft versus host disease and collagenous gastritis. An important gene associated with Lymphocytic Gastritis is GZMB (Granzyme B), and among its related pathways/superpathways are Apoptosis Modulation and Signaling and Allograft rejection. The drugs Esomeprazole and Gastrointestinal Agents have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and liver, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Sources

Related Diseases for Lymphocytic Gastritis

Diseases related to Lymphocytic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 95)

#	Related Disease	Score	Top Affiliating Genes
1	acute graft versus host disease	29.7	GZMB FASLG
2	collagenous gastritis	11.7
3	gastritis	10.8
4	helicobacter pylori infection	10.5
5	chronic erosive gastritis	10.4
6	celiac disease 1	10.3
7	orbit lymphoma	10.3	TIA1 GZMB
8	lymphomatoid granulomatosis	10.3	TIA1 GZMB
9	primary cutaneous anaplastic large cell lymphoma	10.3	TIA1 GZMB
10	composite lymphoma	10.3	TIA1 GZMB
11	hepatosplenic t-cell lymphoma	10.3	TIA1 GZMB
12	giardiasis	10.3	TIA1 GZMB
13	infiltrating lipoma	10.3	TIA1 GZMB
14	dyspepsia	10.2
15	necrotizing sialometaplasia	10.2	TIA1 GZMB
16	ileum cancer	10.2	TIA1 GZMB
17	angioimmunoblastic t-cell lymphoma	10.2	TIA1 GZMB
18	cowpox	10.2	GZMB FAS
19	autoimmune lymphoproliferative syndrome, type v	10.2	TIA1 FAS
20	reticulosarcoma	10.2	TIA1 GZMB
21	gastric adenocarcinoma	10.2
22	breast medullary carcinoma	10.1	GZMB FASLG
23	lymphoma	10.1
24	t-cell large granular lymphocyte leukemia	10.1	GZMB FASLG
25	peripheral t-cell lymphoma	10.1	TIA1 GZMB
26	erythema multiforme	10.1	GZMB FASLG
27	gastric lymphoma	10.0
28	adenocarcinoma	10.0
29	peptic ulcer disease	10.0
30	type ii mixed cryoglobulinemia	10.0	FASLG FAS
31	autoimmune lymphoproliferative syndrome	10.0	FASLG FAS
32	lymphoproliferative syndrome	10.0	FASLG FAS
33	acute myocarditis	10.0	FASLG FAS
34	cutaneous t cell lymphoma	10.0	TIA1 GZMB
35	cartilage-hair hypoplasia	10.0	FASLG FAS
36	alopecia areata	10.0	GZMB FASLG
37	lymphoma, mucosa-associated lymphoid type	10.0
38	thrombophilia due to thrombin defect	10.0
39	gastric cancer	10.0
40	hydrops, lactic acidosis, and sideroblastic anemia	10.0
41	collagenous colitis	10.0
42	lymphocytic colitis	10.0
43	diarrhea	10.0
44	iron metabolism disease	10.0
45	crohn's disease	10.0
46	central nervous system tuberculosis	10.0	FASLG FAS
47	epstein-barr virus-associated gastric carcinoma	9.9	FASLG FAS
48	mycosis fungoides	9.9	TIA1 GZMB
49	silicosis	9.9	FASLG FAS
50	pneumoconiosis	9.8	FASLG FAS

Graphical network of the top 20 diseases related to Lymphocytic Gastritis:

Sources

Symptoms & Phenotypes for Lymphocytic Gastritis

GenomeRNAi Phenotypes related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.17	FAS GZMB TIA1
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.17	FAS FASLG GZMB TIA1

Sources

Drugs & Therapeutics for Lymphocytic Gastritis

Drugs for Lymphocytic Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Esomeprazole

Approved, Investigational

Phase 3

119141-88-7, 161796-78-7, 161973-10-0

9568614 4594

Synonyms:

( -)-Omeprazole

(-)-omeprazole

(−)-omeprazole

(-)-Omeprazole

(-)-Omeprazole magnesium

(S)-(−)-omeprazole

(S)-(-)-Omeprazole

(S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

(S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole

(s)-omeprazole

(S)-omeprazole

(S)-Omeprazole

(S)-Omeprazole magnesium

119141-88-7

119141-89-8

131959-78-9

161973-10-0

172964-80-6

193469-77-1

1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, magnesium salt, trihydrate

2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole

2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole

202742-32-3

217087-09-7

302841-07-2

320416-93-1

326602-80-6

371759-50-1

372519-57-8

376628-34-1

5-methoxy-1H-1,3-benzimidazol-2-yl (4-methoxy-3,5-dimethyl-2-pyridinyl)methyl sulfoxide

5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole

5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole

5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole, magnesium salt (2:1), trihydrate

5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole

6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole

6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

73590-58-6

95382-33-5

AC1L1IIJ

AC1L2XM7

AC1L2XMA

AC1NSJYQ

AC-401

AC-402

AGI-010

AKOS005066653

Alenia

Antra

Antra MUPS

AstraZeneca brand OF esomeprazole magnesium

Audazol

AULCER

Axagon

Belmazol

BIDD:GT0020

BIDD:GT0189

Bio-0888

BPBio1_000425

BRD-A55962179-001-04-9

BSPBio_000385

C07324

CAS-73590-58-6

CCRIS 7099

Ceprandal

CHEBI:50275

CHEBI:519601

CHEBI:7772

CHEMBL1503

CID130564

CID130565

CID4594

CID9568613

CID9568614

CID9579578

CPD000058847

D00455

D01984

D05259

D07917

D-961H

Danlox

DB00338

DB00736

Demeprazol

Desec

Dizprazol

DM-3458

Dudencer

Elgam

Emeproton

Emilok

Epirazole

Erbolin

Escz

Esofag

esomeprazol

Esomeprazol

esomeprazole

Esomeprazole

Ésoméprazole

Esomeprazole (INN)

Esomeprazole [INN:BAN]

Esomeprazole magnesium

Esomeprazole magnesium (USAN)

Esomeprazole magnesium hydrate

Esomeprazole magnesium hydrate (JAN)

Esomeprazole magnesium trihydrate

Esomeprazole potassium

Esomeprazole sodium

Esomeprazole Sodium

Esomeprazole strontium

Esomeprazole strontium anhydrous

esomeprazolum

Esomeprazolum

Esomperazole

Esopral

Exter

Gasec

Gastrimut

Gastroloc

Gibancer

H 168/68

H 168-68

H 199/18

H168/68

H-168/68

H199/18

H-199/18

HMS1528I05

HMS1569D07

HMS2052G17

HMS2090E16

HMS2090F11

HSDB 3575

I06-0705

I06-1976

IDI1_032523

InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20

Indurgan

Inexium paranova

Inexium paranova (TN)

Inhibitron

Inhipump

KS-1054

Lensor

Logastric

Lomac

Losec

Losec, Omesec, Prilosec, Zegerid, Omeprazole

LS-181810

LS-185188

LS-7629

Lucen

magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide

magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide trihydrate

Maybridge4_002645

Mepral

Miol

Miracid

MLS000069373

MLS001076112

MLS001165732

MLS001424148

MolPort-002-885-822

MolPort-003-666-741

MolPort-003-807-515

MolPort-003-849-702

MolPort-005-940-841

MolPort-005-943-880

Mopral

Morecon

N Bis (1H-Benzimidazole,5-methoxy-2-[(S)-[4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl]-)

NCGC00016925-01

NCGC00016925-02

NCGC00021522-03

NCGC00021522-04

NCGC00021522-05

Nexiam

Nexium

Nexium (TN)

Nexium Control

Nexium IV

Nexium, Esomeprazole magnesium

Nilsec

Nopramin

Nuclosina

O0359

O104_SIGMA

Ocid

Olexin

Olit

Omapren

Omebeta

Omebeta 20

Omed

Omegast

OMEP

Omepradex

Omepral

Omeprazol

Omeprazol [INN-Spanish]

omeprazole

Omeprazole (JAN/USP/INN)

Omeprazole [USAN:INN:BAN:JAN]

Omeprazole delayed-release

Omeprazole magnesium

Omeprazole S-form

Omeprazolum

Omeprazolum [INN-Latin]

Omeprazon

Omeprazone

Omeprol

Omesek

Omez

Omezol

Omezolan

Omid

Omisec

Omizac

Ompanyt

OMZ

Ortanol

Osiren

Ozoken

Paprazol

Parizac

Pepticum

Pepticus

Peptilcer

Perprazole

Prazentol

Prazidec

Prazolit

Prestwick_808

Prestwick0_000493

Prestwick1_000493

Prestwick2_000493

Prestwick3_000493

Prilosec

Prilosec (TN)

Prilosec OTC

Prilosec OTC (TN)

Procelac

Proclor

Prysma

Ramezol

Regulacid

Result

S1389_Selleck

S1743_Selleck

SAM001246900

SAN-15

Sanamidol

Secrepina

SMR000058847

SMR000550477

SPBio_002306

ST51053319

STK623746

Strontium, esomeprazole

Tedec Ulceral

TL8005099

Ulceral

Ulcesep

Ulcometion

Ulcozol

Ulcsep

Ulsen

Ultop

Ulzol

UNII-KG60484QX9

UNII-N3PA6559FT

UNII-R6DXU4WAY9

UPCMLD-DP075

UPCMLD-DP075:001

Victrix

Zefxon

Zegerid

Zepral

Zimor

ZINC04693574

ZINC04693575

Zoltum

Gastrointestinal Agents

Phase 3

Antacids

Phase 3

Proton Pump Inhibitors

Phase 3

Anti-Ulcer Agents

Phase 3

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Double-Blind, Randomized, Placebo-Controlled Multicenter Trial on the Efficacy of Esomeprazole Treatment for Patients With Lymphocytic Gastritis	Unknown status	NCT00455754	Phase 3	Esomeprazole

Search NIH Clinical Center for Lymphocytic Gastritis

Sources

Genetic Tests for Lymphocytic Gastritis

Sources

Anatomical Context for Lymphocytic Gastritis

MalaCards organs/tissues related to Lymphocytic Gastritis:

⁴¹

T Cells, Testes, Liver, Pancreas, Salivary Gland, Neutrophil

Sources

Publications for Lymphocytic Gastritis

Articles related to Lymphocytic Gastritis:

(show top 50) (show all 179)

#	Title	Authors	PMID	Year
1	Non-malignant Helicobacter pylori-Associated Diseases. ³⁸	Falkeis-Veits C...Vieth M	31016630	2019
2	Lymphocytic Gastritis Overshadowed by Gastric Mucosa-Associated Lymphoid Tissue Lymphoma. ³⁸	AbdullGaffar B...Keloth T	30773956	2019
3	Lymphocytic gastritis induced by pembrolizumab in a patient with metastatic melanoma. ³⁸	Yip RHL...Yang HM	30256271	2018
4	Associations of Microscopic Colitis With Other Lymphocytic Disorders of the Gastrointestinal Tract. ³⁸	Sonnenberg A...Genta RM	29535059	2018
5	The differential diagnosis of Helicobacter pylori negative gastritis. ³⁸	El-Zimaity H...Riddell R	30255340	2018
6	Subtypes of chronic gastritis in patients with celiac disease before and after gluten-free diet. ³⁸	Gabrieli D...Latella G	29026594	2017
7	Recurrent anaemia in a patient with lymphocytic gastritis and vitamin B12 deficiency. ³⁸	Thereza-Filho MA...Narciso-Schiavon JL	28943131	2017
8	Rare Gastric Lesions Associated with Helicobacter pylori Infection: A Histopathological Review. ³⁸	Joo M	28592787	2017
9	Transverse Myelitis as Manifestation of Celiac Disease in a Toddler. ³⁸	Krom H...Kindermann A	28153851	2017
10	Development of lymphocytic gastritis with recurrent Helicobacter pylori infection. ³⁸	Kim YJ...Jang KS	28211221	2017
11	Lymphocytic Gastritis Identified by Abnormal PET Scan. ³⁸	Murphy CJ...Stanich PP	28462239	2017
12	Propionibacterium acnes overabundance and natural killer group 2 member D system activation in corpus-dominant lymphocytic gastritis. ³⁸	Montalban-Arques A...Gorkiewicz G	27538697	2016
13	The pathological findings seen in laparoscopic sleeve gastrectomies for weight loss. ³⁸	Miller GC...Brown IS	27020497	2016
14	Pathological and Clinical Correlation between Celiac Disease and Helicobacter Pylori Infection; a Review of Controversial Reports. ³⁸	Rostami-Nejad M...Zali MR	27252814	2016
15	Lymphocytic gastritis: clinical, endoscopic and histopathologic features. ³⁸	Ben Rejeb S...Bellil K	27532536	2016
16	Letter: lymphocytic gastritis and coeliac disease. ³⁸	De Giacomo C...Maggiore G	26331558	2015
17	Letter: lymphocytic gastritis and coeliac disease - authors' reply. ³⁸	Lebwohl B...Genta RM	26331559	2015
18	The coeliac stomach: gastritis in patients with coeliac disease. ³⁸	Lebwohl B...Genta RM	25973720	2015
19	Collagenous gastritis: a morphologic and immunohistochemical study of 40 patients. ³⁸	Arnason T...Lauwers GY	25234289	2015
20	Lymphocytic gastritis is not associated with active Helicobacter pylori infection. ³⁸	Nielsen JA...Lewin M	24826984	2014
21	Gastric adenocarcinoma in common variable immunodeficiency: features of cancer and associated gastritis may be characteristic of the condition. ³⁸	De Petris G...Chang YH	24788529	2014
22	Helicobacter pylori Associated Lymphocytic Gastritis in a Child. ³⁸	Kim MJ...Park K	25349835	2014
23	Lymphocytic gastritis showing concomitant occurrence of both CD4 + and CD8 + T-cells among epithelial cells. ³⁸	Fujiwara H...Tsutsumi Y	25047508	2014
24	Pathology and differential diagnosis of chronic, noninfectious gastritis. ³⁸	Polydorides AD	24815937	2014
25	High proportion of granzyme B+ intraepithelial lymphocytes contributes to epithelial apoptosis in Helicobacter pylori-associated lymphocytic gastritis. ³⁸	Han SH...Kim KM	23356909	2013
26	Iron deficiency anemia due to lymphocytic gastritis with Helicobacter pylori infection in childhood: case report. ³⁸	Santalha MF...Pereira F	23528908	2013
27	Endoscopic, ultrasonographic, and pathologic correlation of lymphocytic gastritis. ³⁸	Aggarwal N...Fasanella KE	23716104	2013
28	Endoscopic and histological gastric lesions in children with celiac disease: mucosal involvement is not only confined to the duodenum. ³⁸	Nenna R...Bonamico M	22773062	2012
29	Diffuse type gastric carcinoma presenting as giant gastric folds: lessons learned from six miss diagnosed cases. ³⁸	Mei M...Leimin S	22651965	2012
30	Neutrophilic infiltration in gluten-sensitive enteropathy is neither uncommon nor insignificant: assessment of duodenal biopsies from 267 pediatric and adult patients. ³⁸	Moran CJ...Mino-Kenudson M	22531172	2012
31	Severe spruelike enteropathy associated with olmesartan. ³⁸	Rubio-Tapia A...Murray JA	22728033	2012
32	Gastrointestinal pathology in celiac disease: a case series of 150 consecutive newly diagnosed patients. ³⁸	Brown IS...Rosty C	22706856	2012
33	Hypovitaminosis D as predisposing factor for atrophic type A gastritis: a case-control study and review of the literature on the interaction of Vitamin D with the immune system. ³⁸	Antico A...Bizzaro N	21286859	2012
34	Lymphocytic gastritis in pediatric celiac disease. ³⁸	Bhatti TR...Ruchelli ED	21244234	2011
35	Gastritis in Alaskan racing sled dogs. ³⁸	Ritchey JW...Cragun AS	21247587	2011
36	Gastroduodenal mucosa in microscopic colitis. ³⁸	Koskela RM...Karttunen TJ	21291294	2011
37	Clinical presentation and salivary gland histopathology of paediatric primary Sjögren's syndrome. ³⁸	Saad Magalhaes C...Custodio-Domingues MA	21640054	2011
38	[Functional condition of the stomach, pancreas, liver and gallbladder in celiac disease]. ³⁸	Krums LM...Parfenov AI	21516844	2011
39	Collagenous gastritis. ³⁸	Jain R...Chetty R	19103610	2010
40	Helicobacter pylori-negative gastritis: seek, yet ye shall not always find. ³⁸	Genta RM...Lash RH	20631607	2010
41	Endoscopic portrayal of lymphocytic gastritis in a child. ³⁸	Deb P...Jibaly R	20639772	2010
42	Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. ³⁸	Vakiani E...Bhagat G	19855376	2010
43	Collagenous sprue: a clinicopathologic study of 12 cases. ³⁸	Maguire AA...Sheahan KD	19641452	2009
44	[Helicobacter pylori infection in children with celiac disease]. ³⁸	Ghimpu S...Moraru D	20191880	2009
45	Lymphocytic disorders of the gastrointestinal tract: a review for the practicing pathologist. ³⁸	Carmack SW...Genta RM	19700939	2009
46	Intraepithelial lymphocytes in duodenum from Brazilian adolescents with type 1 diabetes. Influence of Helicobacter pylori. ³⁸	Cabral VL...Miszputen SJ	19017282	2009
47	Collagenous gastritis: histopathologic features and association with other gastrointestinal diseases. ³⁸	Leung ST...Wu TT	19295410	2009
48	Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II. ³⁸	Malamut G...Cellier C	19014942	2009
49	[Lymphocytic gastritis and Menetrier's disease: one or two diseases?]. ³⁸	Maunoury V...Colombel JF	18703299	2009
50	Lymphocytic gastritis and celiac disease in indian children: evidence of a positive relation. ³⁸	Prasad KK...Singh K	18979579	2008

Sources

Genes for Lymphocytic Gastritis

Genes related to Lymphocytic Gastritis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	GZMB	Granzyme B	Protein Coding	22.04	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	TIA1	TIA1 Cytotoxic Granule Associated RNA Binding Protein	Protein Coding	21.88	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	FAS	Fas Cell Surface Death Receptor	Protein Coding	19.73	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	FASLG	Fas Ligand	Protein Coding	19.49	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	B3GAT1	Beta-1,3-Glucuronyltransferase 1	Protein Coding	15.42	DISEASES inferred ¹⁵
6	CD8A	CD8a Molecule	Protein Coding	14.91	DISEASES inferred ¹⁵

Sources

Variations for Lymphocytic Gastritis

Sources

Expression for Lymphocytic Gastritis

Search GEO for disease gene expression data for Lymphocytic Gastritis.

Sources

Pathways for Lymphocytic Gastritis

Pathways related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

(show all 15)

#	Super pathways	Score	Top Affiliating Genes
1	Apoptosis Modulation and Signaling ¹ Show member pathways Apoptosis ³⁷ Apoptosis ¹ Apoptosis and survival Apoptotic TNF-family pathways ²² Apoptosis Signaling Pathways ⁶⁵ Death Receptor Signaling ⁶⁷	12.4	GZMB FASLG FAS
2	Allograft rejection ³⁷ ¹ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	12.36	GZMB FASLG FAS CD8A
3	DREAM Repression and Dynorphin Expression ⁶⁴ Show member pathways BMP Pathway ⁶⁴ Calpain Protease Regulates Cellular Mechanics ⁶⁴ Caspase Cascade ⁶⁴ Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels ⁶⁶ nNOS Signaling in Skeletal Muscle ⁶⁴ TOB in Osteoblast Signaling ⁶⁴	12.18	GZMB FASLG FAS
4	Immune response Role of DAP12 receptors in NK cells ²² Show member pathways Immune response CD16 signaling in NK cells ²² Natural killer cell mediated cytotoxicity ³⁷	12.11	GZMB FASLG FAS
5	NF-kappaB Signaling ⁴	11.97	GZMB FASLG FAS CD8A
6	Apoptosis and survival Caspase cascade ²² Show member pathways Apoptosis and survival FAS signaling cascades ²² Breakdown of the nuclear lamina ⁶⁶ Caspase cascade in apoptosis ¹ Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation ¹ FasL/ CD95L signaling ⁶⁶ Influenza A virus infection ¹	11.8	GZMB FASLG FAS
7	IL12-mediated signaling events ¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²²	11.49	GZMB FASLG CD8A
8	Nanomaterial induced apoptosis ¹ Show member pathways Activation and oligomerization of BAK protein ⁶⁶ Apoptosis - multiple species ³⁷ Apoptosis Modulation by HSP70 ¹ Apoptotic factor-mediated response ⁶⁶ Release of apoptotic factors from the mitochondria ⁶⁶	11.47	FASLG FAS
9	Innate Lymphoid Cell Differentiation Pathways ⁶⁵	11.44	GZMB CD8A
10	Platinum drug resistance ³⁷	11.37	FASLG FAS
11	Photodynamic therapy-induced AP-1 survival signaling. ¹	11.2	FASLG FAS
12	Apoptosis and Autophagy ⁴	11.19	TIA1 GZMB FASLG FAS
13	Signal transduction_JNK pathway ²²	11.12	FASLG FAS
14	African trypanosomiasis ³⁷	11	FASLG FAS
15	Downstream signaling in naive CD8+ T cells ¹ Show member pathways Ras signaling in the CD4+ TCR pathway ¹	10.92	GZMB FASLG CD8A

Sources

GO Terms for Lymphocytic Gastritis

Biological processes related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	immune response	GO:0006955	9.58	FASLG FAS CD8A
2	apoptotic process	GO:0006915	9.46	TIA1 GZMB FASLG FAS
3	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO:0006919	9.43	FASLG FAS
4	apoptotic signaling pathway	GO:0097190	9.37	FASLG FAS
5	extrinsic apoptotic signaling pathway	GO:0097191	9.32	FASLG FAS
6	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO:1902042	9.26	FASLG FAS
7	regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO:1902041	8.96	FASLG FAS
8	necroptotic signaling pathway	GO:0097527	8.62	FASLG FAS

Sources

Sources for Lymphocytic Gastritis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ TGDB

⁷¹ Tocris

⁷² UMLS

⁷³ UMLS via Orphanet

⁷⁴ UniProtKB/Swiss-Prot

⁷⁵ Wikipedia