Lymphoepithelioma-Like Thymic Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lymphoepithelioma-Like Thymic Carcinoma

MalaCards integrated aliases for Lymphoepithelioma-Like Thymic Carcinoma:

Name: Lymphoepithelioma-Like Thymic Carcinoma ¹² ¹⁵

Lymphoepithelioma-Like Carcinoma of the Thymus ¹²

Thymic Lymphoepithelioma-Like Carcinoma ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Immune diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7599

NCIt ⁵⁰ C7998

UMLS ⁷³ C0279706

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Summaries for Lymphoepithelioma-Like Thymic Carcinoma

MalaCards based summary : Lymphoepithelioma-Like Thymic Carcinoma, also known as lymphoepithelioma-like carcinoma of the thymus, is related to thymus cancer and lymphoepithelioma-like carcinoma, and has symptoms including chest pain, coughing and dyspnea. An important gene associated with Lymphoepithelioma-Like Thymic Carcinoma is CD5 (CD5 Molecule), and among its related pathways/superpathways is Allograft rejection. Affiliated tissues include thymus.

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Related Diseases for Lymphoepithelioma-Like Thymic Carcinoma

Diseases related to Lymphoepithelioma-Like Thymic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)

#	Related Disease	Score	Top Affiliating Genes
1	thymus cancer	10.4
2	lymphoepithelioma-like carcinoma	10.0
3	nephrotic syndrome	10.0
4	polymyositis	10.0
5	paraneoplastic syndromes	10.0
6	papillary thymic adenocarcinoma	9.8	CD5 TG
7	autoimmune disease of endocrine system	9.6	FOXP3 TG
8	alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity	9.5	FOXP3 TG
9	hypersensitivity reaction disease	9.5	FOXP3 TG
10	immune system disease	9.4	FOXP3 TG
11	celiac disease 1	9.3	FOXP3 TG
12	diabetes mellitus, insulin-dependent	9.2	FOXP3 TG
13	autoimmune disease	9.0	FOXP3 TG

Graphical network of the top 20 diseases related to Lymphoepithelioma-Like Thymic Carcinoma:

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Symptoms & Phenotypes for Lymphoepithelioma-Like Thymic Carcinoma

UMLS symptoms related to Lymphoepithelioma-Like Thymic Carcinoma:

chest pain, coughing, dyspnea, fatigue, fever

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Drugs & Therapeutics for Lymphoepithelioma-Like Thymic Carcinoma

Search Clinical Trials , NIH Clinical Center for Lymphoepithelioma-Like Thymic Carcinoma

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Genetic Tests for Lymphoepithelioma-Like Thymic Carcinoma

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Anatomical Context for Lymphoepithelioma-Like Thymic Carcinoma

MalaCards organs/tissues related to Lymphoepithelioma-Like Thymic Carcinoma:

⁴¹

Thymus

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Publications for Lymphoepithelioma-Like Thymic Carcinoma

Articles related to Lymphoepithelioma-Like Thymic Carcinoma:

#	Title	Authors	Year
1	A rare highly aggressive tumour: lymphoepithelioma-like thymic carcinoma. ( 28942409 )	Gomez J.M.D....Abrams R.	2017
2	Response to chemotherapy with carboplatin plus albumin-bound paclitaxel in a patient with lymphoepithelioma-like thymic carcinoma: A case report. ( 27123268 )	Shima H....Mishima M.	2016
3	Epstein-Barr virus (EBV) associated lymphoepithelioma-like thymic carcinoma associated with paraneoplastic syndrome of polymyositis: a rare tumor with rare association. ( 19893401 )	Koppula B.R....Lewis D.H.	2009
4	Lymphoepithelioma-like thymic carcinoma in a 16-year-old boy with nephrotic syndrome--a case report. ( 18046582 )	KiliA9-PstrusiA8ska K....Dobaczewski G.	2008
5	Detection of Epstein-Barr virus DNA in a Japanese case of lymphoepithelioma-like thymic carcinoma. ( 1313408 )	Matsuno Y....Shimosato Y.	1992

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Genes for Lymphoepithelioma-Like Thymic Carcinoma

Genes related to Lymphoepithelioma-Like Thymic Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CD5	CD5 Molecule	Protein Coding	14.7	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	FOXP3	Forkhead Box P3	Protein Coding	14.33	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	TG	Thyroglobulin	Protein Coding	14.31	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Lymphoepithelioma-Like Thymic Carcinoma

Cosmic variations for Lymphoepithelioma-Like Thymic Carcinoma:

⁹

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM44380	TP53	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.376T>A	p.Y126N	17:7675236-7675236	3
2	COSM14140	SMAD4	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.1081C>T	p.R361C	18:51065548-51065548	3
3	COSM6191487	PREX2	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.107G>T	p.R36L	8:67952501-67952501	3
4	COSM6191489	NOTCH2	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.3359G>A	p.C1120Y	1:119937445-119937445	3
5	COSM2006821	KMT2D	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.11824C>T	p.R3942W	12:49032071-49032071	3
6	COSM133763	KIT	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.1657T>A	p.Y553N	4:54727425-54727425	3
7	COSM6191682	KDM6A	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.2921C>T	p.A974V	23:45078488-45078488	3
8	COSM6196604	IL7R	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.537+1G>T	p.?	5:35871214-35871214	3
9	COSM6191486	FAT1	thymus,NS,thymic carcinoma,undifferentiated carcinoma	c.12706A>G	p.K4236E	4:186596834-186596834	3

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Expression for Lymphoepithelioma-Like Thymic Carcinoma

Search GEO for disease gene expression data for Lymphoepithelioma-Like Thymic Carcinoma.

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Pathways for Lymphoepithelioma-Like Thymic Carcinoma

Pathways related to Lymphoepithelioma-Like Thymic Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	11.36	FOXP3 TG

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GO Terms for Lymphoepithelioma-Like Thymic Carcinoma

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Sources for Lymphoepithelioma-Like Thymic Carcinoma

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⁷⁶ Wikipedia