MCID: LYM001
MIFTS: 23

Lymphohistiocytoid Mesothelioma

Categories: Cancer diseases, Immune diseases, Respiratory diseases
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Aliases & Classifications for Lymphohistiocytoid Mesothelioma

MalaCards integrated aliases for Lymphohistiocytoid Mesothelioma:

Name: Lymphohistiocytoid Mesothelioma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:7381
NCIt 49 C27779
UMLS 71 C1334464

Summaries for Lymphohistiocytoid Mesothelioma

MalaCards based summary: Lymphohistiocytoid Mesothelioma is related to liposarcoma and thymoma. An important gene associated with Lymphohistiocytoid Mesothelioma is HEG1 (Heart Development Protein With EGF Like Domains 1), and among its related pathways/superpathways are Vitamin D receptor pathway and Hematopoietic Stem Cells and Lineage-specific Markers. Related phenotypes are growth/size/body region and cellular

Related Diseases for Lymphohistiocytoid Mesothelioma

Diseases related to Lymphohistiocytoid Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 30.1 CDKN2A CD68 CALB2
2 thymoma 30.0 NKX2-1 CDKN2A CALB2
3 sarcomatoid mesothelioma 29.3 PTGER4 PDPN KRT5 HEG1 CLDN4 CDKN2A
4 benign mesothelioma 29.1 THBD PDPN NKX2-1 KRT5 CEACAM5 CDKN2A
5 mesothelioma, malignant 28.7 THBD PTGER4 PDPN NKX2-1 KRT5 CEACAM5
6 parovarian cyst 10.3 CEACAM5 CD86
7 pericardial tuberculosis 10.3 CEACAM5 CALB2
8 epididymal neoplasm 10.3 CD68 CALB2
9 tuberculous peritonitis 10.3 CEACAM5 CALB2
10 liver leiomyoma 10.3 CEACAM5 CALB2
11 breast granular cell tumor 10.3 CD68 CALB2
12 pancreatic mucinous cystadenoma 10.3 CEACAM5 CALB2
13 peritoneal serous papillary adenocarcinoma 10.3 PTGER4 CLDN4
14 squamous papillomatosis 10.3 PTGER4 CEACAM5
15 pleural lipoma 10.2 CD68 CALB2
16 bile duct cystadenocarcinoma 10.2 MUC13 CEACAM5
17 ovarian gonadoblastoma 10.2 CEACAM5 CALB2
18 penis basal cell carcinoma 10.2 PTGER4 CDKN2A
19 fox-fordyce disease 10.2 CEACAM5 CD68
20 cervix endometriosis 10.2 CDKN2A CALB2
21 chest wall lipoma 10.2 CEACAM5 CD68
22 acute cholangitis 10.2 THBD CEACAM5
23 large cell carcinoma with rhabdoid phenotype 10.2 CLDN4 CALB2
24 adenofibroma 10.2 PAX8 CALB2
25 lung leiomyosarcoma 10.2 KRT5 CALB2
26 rete testis adenoma 10.2 PAX8 CALB2
27 liver leiomyosarcoma 10.2 CEACAM5 CALB2
28 wolffian duct adenocarcinoma 10.2 PAX8 CALB2
29 sarcomatoid basal cell carcinoma 10.2 PTGER4 KRT5
30 esophageal tuberculosis 10.2 CEACAM5 CD68
31 vagina leiomyoma 10.2 CEACAM5 CDKN2A
32 fallopian tube adenocarcinoma 10.2 PAX8 CALB2
33 adult type testicular granulosa cell tumor 10.2 KRT5 CALB2
34 vulval paget's disease 10.2 CEACAM5 CDKN2A
35 spindle cell thymoma 10.2 KRT5 CALB2
36 female urethral cancer 10.2 CEACAM5 CDKN2A
37 pulmonary artery leiomyosarcoma 10.2 CEACAM5 CD68
38 bladder adenocarcinoma 10.2 THBD CEACAM5
39 gallbladder signet ring cell adenocarcinoma 10.2 PAX8 CALB2
40 cystadenofibroma 10.2 PAX8 CALB2
41 eccrine porocarcinoma 10.2 KRT5 CEACAM5
42 metatypical basal cell carcinoma 10.2 PTGER4 KRT5
43 papillary thymic adenocarcinoma 10.2 PTGER4 CEACAM5 CALB2
44 hidradenoma 10.2 KRT5 CEACAM5
45 uterus perivascular epithelioid cell tumor 10.2 PAX8 CALB2
46 fallopian tube serous adenocarcinoma 10.2 PTGER4 CEACAM5 CALB2
47 comedo carcinoma 10.2 PTGER4 KRT5
48 mucoepidermoid esophageal carcinoma 10.2 KRT5 CEACAM5
49 ovarian serous cystadenofibroma 10.2 PAX8 CALB2
50 ovarian serous adenofibroma 10.2 PAX8 CALB2

Graphical network of the top 20 diseases related to Lymphohistiocytoid Mesothelioma:



Diseases related to Lymphohistiocytoid Mesothelioma

Symptoms & Phenotypes for Lymphohistiocytoid Mesothelioma

MGI Mouse Phenotypes related to Lymphohistiocytoid Mesothelioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.17 CDKN2A CEACAM5 CLDN4 HEG1 KRT5 MUC13
2 cellular MP:0005384 10.07 CD86 CDKN2A CEACAM5 CLDN4 HEG1 MUC13
3 cardiovascular system MP:0005385 10.02 CDKN2A CEACAM5 CLDN4 HEG1 MUC13 NKX2-1
4 behavior/neurological MP:0005386 10 CALB2 CD86 CDKN2A CEACAM5 CLDN4 HEG1
5 digestive/alimentary MP:0005381 9.95 CDKN2A CEACAM5 KRT5 MUC13 NKX2-1 PDPN
6 immune system MP:0005387 9.85 CD68 CD86 CDKN2A CEACAM5 HEG1 KRT5
7 respiratory system MP:0005388 9.43 CDKN2A HEG1 NKX2-1 PDPN PTGER4 THBD
8 mortality/aging MP:0010768 9.36 CDKN2A CEACAM5 CLDN4 HEG1 KRT5 MUC13

Drugs & Therapeutics for Lymphohistiocytoid Mesothelioma

Search Clinical Trials, NIH Clinical Center for Lymphohistiocytoid Mesothelioma

Genetic Tests for Lymphohistiocytoid Mesothelioma

Anatomical Context for Lymphohistiocytoid Mesothelioma

Publications for Lymphohistiocytoid Mesothelioma

Articles related to Lymphohistiocytoid Mesothelioma:

# Title Authors PMID Year
1
A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis. 62
29187476 2017
2
Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings. 62
22021116 2013
3
Localized malignant lymphohistiocytoid pleural mesothelioma. 62
21520787 2011
4
Lymphohistiocytoid mesothelioma of the pleura. 62
20618734 2010
5
Localized malignant mesothelioma in the middle mediastinum: report of a case. 62
18612789 2008
6
[Mesotheliomas with leucocytic infiltration]. 62
15205913 2004
7
Lymphohistiocytoid mesothelioma: a clinical, immunohistochemical and ultrastructural study of four cases and literature review. 62
15693633 2004
8
Lymphohistiocytoid mesothelioma. An often misdiagnosed variant of sarcomatoid malignant mesothelioma. 62
10800396 2000
9
Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma. 62
2458647 1988

Variations for Lymphohistiocytoid Mesothelioma

Expression for Lymphohistiocytoid Mesothelioma

Search GEO for disease gene expression data for Lymphohistiocytoid Mesothelioma.

Pathways for Lymphohistiocytoid Mesothelioma

Pathways related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.6 THBD PTGER4 CDKN2A
2 11.2 CEACAM5 CD86 CD68
3 9.58 CD86 CD68

GO Terms for Lymphohistiocytoid Mesothelioma

Biological processes related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lung development GO:0030324 9.1 PDPN NKX2-1 HEG1

Sources for Lymphohistiocytoid Mesothelioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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