Lymphohistiocytoid Mesothelioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lymphohistiocytoid Mesothelioma

MalaCards integrated aliases for Lymphohistiocytoid Mesothelioma:

Name: Lymphohistiocytoid Mesothelioma ¹² ¹⁵ ⁷⁰

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7381

NCIt ⁵⁰ C27779

UMLS ⁷⁰ C1334464

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Summaries for Lymphohistiocytoid Mesothelioma

MalaCards based summary : Lymphohistiocytoid Mesothelioma is related to sarcomatoid mesothelioma and benign mesothelioma. An important gene associated with Lymphohistiocytoid Mesothelioma is CALB2 (Calbindin 2), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are hematopoietic system and immune system

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Related Diseases for Lymphohistiocytoid Mesothelioma

Diseases related to Lymphohistiocytoid Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)

#	Related Disease	Score	Top Affiliating Genes
1	sarcomatoid mesothelioma	30.6	THBD CDKN2A CALB2
2	benign mesothelioma	30.2	THBD CEACAM5 CDKN2A CALB2
3	mesothelioma, malignant	30.0	THBD CEACAM5 CDKN2A CALB2
4	liposarcoma	29.9	CDKN2A CD68 CALB2
5	thymoma	29.7	CD8A CD5 CALB2
6	liver fibroma	10.3	THBD CALB2
7	lung sarcomatoid carcinoma	10.3	THBD CALB2
8	malignant biphasic mesothelioma	10.3	THBD CALB2
9	nephrogenic adenoma of the urethra	10.3	THBD CALB2
10	rete testis neoplasm	10.3	PTGER4 CALB2
11	rete testis adenocarcinoma	10.3	PTGER4 CALB2
12	postinflammatory pulmonary fibrosis	10.2	THBD CD86
13	peritoneal serous adenocarcinoma	10.2	PTGER4 CALB2
14	epididymal neoplasm	10.2	CD68 CALB2
15	sertoli-leydig cell tumor	10.2	THBD CALB2
16	pilar sheath acanthoma	10.2	PTGER4 CALB2
17	spindle cell thymoma	10.2	CD5 CALB2
18	dermoid cyst of ovary	10.2	CEACAM5 CALB2
19	asbestosis	10.2	THBD CALB2
20	pericardial tuberculosis	10.2	CEACAM5 CALB2
21	pancreatic mucinous cystadenoma	10.2	CEACAM5 CALB2
22	cystadenoma	10.2	CEACAM5 CALB2
23	thyroid angiosarcoma	10.2	THBD CEACAM5
24	ovarian benign neoplasm	10.2	CEACAM5 CALB2
25	ovarian germ cell cancer	10.2	CEACAM5 CALB2
26	acute cholangitis	10.2	THBD CEACAM5
27	seminal vesicle adenocarcinoma	10.2	CEACAM5 CALB2
28	granular cell tumor	10.2	CD68 CALB2
29	malignant syringoma	10.1	PTGER4 CEACAM5
30	papillary serous adenocarcinoma	10.1	CEACAM5 CALB2
31	eccrine sweat gland cancer	10.1	PTGER4 CEACAM5
32	polycystic liver disease 1 with or without kidney cysts	10.1	CEACAM5 CALB2
33	connective tissue benign neoplasm	10.1	CD68 CALB2
34	squamous papillomatosis	10.1	PTGER4 CEACAM5
35	mixed cell type cancer	10.1	CEACAM5 CALB2
36	fox-fordyce disease	10.1	CEACAM5 CD68
37	cystic basal cell carcinoma	10.1	PTGER4 CEACAM5
38	sex cord-gonadal stromal tumor	10.1	CEACAM5 CALB2
39	fallopian tube endometrioid adenocarcinoma	10.1	CDKN2A CALB2
40	liver sarcoma	10.1	CEACAM5 CD68
41	ovarian brenner tumor	10.1	THBD CDKN2A
42	xanthogranulomatous cholecystitis	10.1	CEACAM5 CD68
43	esophageal tuberculosis	10.1	CEACAM5 CD68
44	thymus adenocarcinoma	10.1	CEACAM5 CD5
45	actinobacillosis	10.1	CD68 CD5
46	adenomatoid tumor	10.1	THBD PTGER4 CALB2
47	thymoma, familial	10.1
48	malignant fibrous histiocytoma	10.1
49	gangliocytoma	10.1
50	fibrous histiocytoma	10.1

Graphical network of the top 20 diseases related to Lymphohistiocytoid Mesothelioma:

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Symptoms & Phenotypes for Lymphohistiocytoid Mesothelioma

MGI Mouse Phenotypes related to Lymphohistiocytoid Mesothelioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	9.5	CD5 CD68 CD86 CD8A CDKN2A PTGER4
2	immune system	MP:0005387	9.17	CD5 CD68 CD86 CD8A CDKN2A PTGER4

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Drugs & Therapeutics for Lymphohistiocytoid Mesothelioma

Search Clinical Trials , NIH Clinical Center for Lymphohistiocytoid Mesothelioma

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Genetic Tests for Lymphohistiocytoid Mesothelioma

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Anatomical Context for Lymphohistiocytoid Mesothelioma

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Publications for Lymphohistiocytoid Mesothelioma

Articles related to Lymphohistiocytoid Mesothelioma:

#	Title	Authors	PMID	Year
1	A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis. ⁶¹	Matsubara T...Maehara Y	29187476	2017
2	Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings. ⁶¹	Tresserra F...Ramos C	22021116	2013
3	Localized malignant lymphohistiocytoid pleural mesothelioma. ⁶¹	Ouazzani A...Cappello M	21520787	2011
4	Lymphohistiocytoid mesothelioma of the pleura. ⁶¹	Kawai T...Nakatani Y	20618734	2010
5	Localized malignant mesothelioma in the middle mediastinum: report of a case. ⁶¹	Akamoto S...Hayashi K	18612789	2008
6	[Mesotheliomas with leucocytic infiltration]. ⁶¹	Dorfmuller P...Muller KM	15205913	2004
7	Lymphohistiocytoid mesothelioma: a clinical, immunohistochemical and ultrastructural study of four cases and literature review. ⁶¹	Yao DX...Klimstra DS	15693633	2004
8	Lymphohistiocytoid mesothelioma. An often misdiagnosed variant of sarcomatoid malignant mesothelioma. ⁶¹	Khalidi HS...Battifora H	10800396	2000
9	Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma. ⁶¹	Henderson DW...Steele RH	2458647	1988

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Genes for Lymphohistiocytoid Mesothelioma

Genes related to Lymphohistiocytoid Mesothelioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CALB2	Calbindin 2	Protein Coding	13.38	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	THBD	Thrombomodulin	Protein Coding	11.87	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	CD86	CD86 Molecule	Protein Coding	5.19	DISEASES inferred ¹⁵
4	PTGER4	Prostaglandin E Receptor 4	Protein Coding	5.1	DISEASES inferred ¹⁵
5	CD68	CD68 Molecule	Protein Coding	4.26	DISEASES inferred ¹⁵
6	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	4.13	DISEASES inferred ¹⁵
7	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	3.94	DISEASES inferred ¹⁵
8	CD8A	CD8a Molecule	Protein Coding	3.45	DISEASES inferred ¹⁵
9	CD5	CD5 Molecule	Protein Coding	3.23	DISEASES inferred ¹⁵

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Variations for Lymphohistiocytoid Mesothelioma

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Expression for Lymphohistiocytoid Mesothelioma

Search GEO for disease gene expression data for Lymphohistiocytoid Mesothelioma.

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Pathways for Lymphohistiocytoid Mesothelioma

Pathways related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.09	CEACAM5 CD8A CD86 CD68 CD5

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GO Terms for Lymphohistiocytoid Mesothelioma

Cellular components related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	8.92	THBD CD8A CD86 CD5

Biological processes related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	T cell costimulation	GO:0031295	8.62	CD86 CD5

Molecular functions related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	coreceptor activity	GO:0015026	8.96	CD8A CD86
2	signaling receptor activity	GO:0038023	8.8	THBD CD86 CD5

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Sources for Lymphohistiocytoid Mesothelioma

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⁶⁹ Tocris

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⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia