MCID: LYM001
MIFTS: 21

Lymphohistiocytoid Mesothelioma

Categories: Cancer diseases, Immune diseases, Respiratory diseases

Aliases & Classifications for Lymphohistiocytoid Mesothelioma

MalaCards integrated aliases for Lymphohistiocytoid Mesothelioma:

Name: Lymphohistiocytoid Mesothelioma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7381
NCIt 50 C27779
UMLS 70 C1334464

Summaries for Lymphohistiocytoid Mesothelioma

MalaCards based summary : Lymphohistiocytoid Mesothelioma is related to sarcomatoid mesothelioma and benign mesothelioma. An important gene associated with Lymphohistiocytoid Mesothelioma is CALB2 (Calbindin 2), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are hematopoietic system and immune system

Related Diseases for Lymphohistiocytoid Mesothelioma

Diseases related to Lymphohistiocytoid Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)
# Related Disease Score Top Affiliating Genes
1 sarcomatoid mesothelioma 30.6 THBD CDKN2A CALB2
2 benign mesothelioma 30.2 THBD CEACAM5 CDKN2A CALB2
3 mesothelioma, malignant 30.0 THBD CEACAM5 CDKN2A CALB2
4 liposarcoma 29.9 CDKN2A CD68 CALB2
5 thymoma 29.7 CD8A CD5 CALB2
6 liver fibroma 10.3 THBD CALB2
7 lung sarcomatoid carcinoma 10.3 THBD CALB2
8 malignant biphasic mesothelioma 10.3 THBD CALB2
9 nephrogenic adenoma of the urethra 10.3 THBD CALB2
10 rete testis neoplasm 10.3 PTGER4 CALB2
11 rete testis adenocarcinoma 10.3 PTGER4 CALB2
12 postinflammatory pulmonary fibrosis 10.2 THBD CD86
13 peritoneal serous adenocarcinoma 10.2 PTGER4 CALB2
14 epididymal neoplasm 10.2 CD68 CALB2
15 sertoli-leydig cell tumor 10.2 THBD CALB2
16 pilar sheath acanthoma 10.2 PTGER4 CALB2
17 spindle cell thymoma 10.2 CD5 CALB2
18 dermoid cyst of ovary 10.2 CEACAM5 CALB2
19 asbestosis 10.2 THBD CALB2
20 pericardial tuberculosis 10.2 CEACAM5 CALB2
21 pancreatic mucinous cystadenoma 10.2 CEACAM5 CALB2
22 cystadenoma 10.2 CEACAM5 CALB2
23 thyroid angiosarcoma 10.2 THBD CEACAM5
24 ovarian benign neoplasm 10.2 CEACAM5 CALB2
25 ovarian germ cell cancer 10.2 CEACAM5 CALB2
26 acute cholangitis 10.2 THBD CEACAM5
27 seminal vesicle adenocarcinoma 10.2 CEACAM5 CALB2
28 granular cell tumor 10.2 CD68 CALB2
29 malignant syringoma 10.1 PTGER4 CEACAM5
30 papillary serous adenocarcinoma 10.1 CEACAM5 CALB2
31 eccrine sweat gland cancer 10.1 PTGER4 CEACAM5
32 polycystic liver disease 1 with or without kidney cysts 10.1 CEACAM5 CALB2
33 connective tissue benign neoplasm 10.1 CD68 CALB2
34 squamous papillomatosis 10.1 PTGER4 CEACAM5
35 mixed cell type cancer 10.1 CEACAM5 CALB2
36 fox-fordyce disease 10.1 CEACAM5 CD68
37 cystic basal cell carcinoma 10.1 PTGER4 CEACAM5
38 sex cord-gonadal stromal tumor 10.1 CEACAM5 CALB2
39 fallopian tube endometrioid adenocarcinoma 10.1 CDKN2A CALB2
40 liver sarcoma 10.1 CEACAM5 CD68
41 ovarian brenner tumor 10.1 THBD CDKN2A
42 xanthogranulomatous cholecystitis 10.1 CEACAM5 CD68
43 esophageal tuberculosis 10.1 CEACAM5 CD68
44 thymus adenocarcinoma 10.1 CEACAM5 CD5
45 actinobacillosis 10.1 CD68 CD5
46 adenomatoid tumor 10.1 THBD PTGER4 CALB2
47 thymoma, familial 10.1
48 malignant fibrous histiocytoma 10.1
49 gangliocytoma 10.1
50 fibrous histiocytoma 10.1

Graphical network of the top 20 diseases related to Lymphohistiocytoid Mesothelioma:



Diseases related to Lymphohistiocytoid Mesothelioma

Symptoms & Phenotypes for Lymphohistiocytoid Mesothelioma

MGI Mouse Phenotypes related to Lymphohistiocytoid Mesothelioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CD5 CD68 CD86 CD8A CDKN2A PTGER4
2 immune system MP:0005387 9.17 CD5 CD68 CD86 CD8A CDKN2A PTGER4

Drugs & Therapeutics for Lymphohistiocytoid Mesothelioma

Search Clinical Trials , NIH Clinical Center for Lymphohistiocytoid Mesothelioma

Genetic Tests for Lymphohistiocytoid Mesothelioma

Anatomical Context for Lymphohistiocytoid Mesothelioma

Publications for Lymphohistiocytoid Mesothelioma

Articles related to Lymphohistiocytoid Mesothelioma:

# Title Authors PMID Year
1
A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis. 61
29187476 2017
2
Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings. 61
22021116 2013
3
Localized malignant lymphohistiocytoid pleural mesothelioma. 61
21520787 2011
4
Lymphohistiocytoid mesothelioma of the pleura. 61
20618734 2010
5
Localized malignant mesothelioma in the middle mediastinum: report of a case. 61
18612789 2008
6
[Mesotheliomas with leucocytic infiltration]. 61
15205913 2004
7
Lymphohistiocytoid mesothelioma: a clinical, immunohistochemical and ultrastructural study of four cases and literature review. 61
15693633 2004
8
Lymphohistiocytoid mesothelioma. An often misdiagnosed variant of sarcomatoid malignant mesothelioma. 61
10800396 2000
9
Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma. 61
2458647 1988

Variations for Lymphohistiocytoid Mesothelioma

Expression for Lymphohistiocytoid Mesothelioma

Search GEO for disease gene expression data for Lymphohistiocytoid Mesothelioma.

Pathways for Lymphohistiocytoid Mesothelioma

Pathways related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.09 CEACAM5 CD8A CD86 CD68 CD5

GO Terms for Lymphohistiocytoid Mesothelioma

Cellular components related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.92 THBD CD8A CD86 CD5

Biological processes related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell costimulation GO:0031295 8.62 CD86 CD5

Molecular functions related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 coreceptor activity GO:0015026 8.96 CD8A CD86
2 signaling receptor activity GO:0038023 8.8 THBD CD86 CD5

Sources for Lymphohistiocytoid Mesothelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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