Lymphohistiocytoid Mesothelioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lymphohistiocytoid Mesothelioma

MalaCards integrated aliases for Lymphohistiocytoid Mesothelioma:

Name: Lymphohistiocytoid Mesothelioma ¹² ¹⁵ ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7381

NCIt ⁵⁰ C27779

UMLS ⁷³ C1334464

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Summaries for Lymphohistiocytoid Mesothelioma

MalaCards based summary : Lymphohistiocytoid Mesothelioma is related to sarcomatoid mesothelioma and adenomatoid tumor. An important gene associated with Lymphohistiocytoid Mesothelioma is THBD (Thrombomodulin), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include lung, kidney and liver, and related phenotypes are hematopoietic system and immune system

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Related Diseases for Lymphohistiocytoid Mesothelioma

Diseases related to Lymphohistiocytoid Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)

#	Related Disease	Score	Top Affiliating Genes
1	sarcomatoid mesothelioma	30.4	CDKN2A THBD
2	adenomatoid tumor	10.2	CALB2 THBD
3	malignant epithelial mesothelioma	10.2	PTGER4 THBD
4	papillary thymic adenocarcinoma	10.2	CALB2 PTGER4
5	cervix endometriosis	10.1	CALB2 CEACAM5
6	bile duct cystadenocarcinoma	10.1	CALB2 CEACAM5
7	gallbladder squamous cell carcinoma	10.1	CD86 CEACAM5
8	ovarian brenner tumor	10.1	CALB2 THBD
9	mucinous ovarian cystadenoma	10.1	CALB2 CEACAM5
10	nodular hidradenoma	10.1	CEACAM5 PTGER4
11	fallopian tube endometrioid adenocarcinoma	10.1	CALB2 CDKN2A
12	thymus adenocarcinoma	10.1	CEACAM5 PTGER4
13	pancreatic mucinous cystadenoma	10.1	CALB2 CEACAM5
14	bartholin's gland benign neoplasm	10.1	CD86 CDKN2A
15	skin carcinoma in situ	10.1	CD86 CDKN2A
16	pericardial tuberculosis	10.1	CEACAM5 PTGER4
17	mixed ductal-endocrine carcinoma	10.1	CALB2 CEACAM5
18	peritoneal mesothelioma	10.1	CDKN2A THBD
19	mucinous bronchioloalveolar adenocarcinoma	10.1	CALB2 CDKN2A
20	bartholin's gland disease	10.1	CD86 CDKN2A
21	pleural cancer	10.0	CALB2 CDKN2A
22	chondroid chordoma	10.0	CEACAM5 EPCAM
23	pleural disease	10.0	CALB2 CEACAM5
24	pericardium cancer	10.0	CALB2 PTGER4 THBD
25	pericardial mesothelioma	10.0	CALB2 PTGER4 THBD
26	adenoid basal cell carcinoma	10.0	CDKN2A CEACAM5
27	lymphoepithelioma-like thymic carcinoma	10.0	CDKN2A EPCAM
28	bile duct adenocarcinoma	10.0	CEACAM5 EPCAM
29	polycystic liver disease 1 with or without kidney cysts	10.0	CALB2 CEACAM5
30	pneumatosis cystoides intestinalis	10.0	CALB2 CD68
31	granulomatous angiitis	10.0	CD68 THBD
32	malignant pleural mesothelioma	10.0	CALB2 CDKN2A THBD
33	fox-fordyce disease	10.0	CD68 CEACAM5
34	miliaria	10.0	CD68 CEACAM5
35	epididymis cancer	10.0	CD86 CEACAM5 PTGER4
36	epididymis adenocarcinoma	10.0	CD86 CEACAM5 PTGER4
37	liver sarcoma	9.9	CD68 CEACAM5
38	esophageal disease	9.9	CDKN2A CEACAM5
39	clear cell acanthoma	9.9	CD68 CEACAM5
40	melanomatosis	9.9	CD68 CDKN2A
41	bladder carcinoma in situ	9.9	CD68 CDKN2A
42	scrotal carcinoma	9.9	CD68 CDKN2A
43	conventional leiomyosarcoma	9.9	CD68 CDKN2A
44	congenital epulis	9.9	CD68 CEACAM5
45	xanthogranulomatous cholecystitis	9.9	CD68 CEACAM5
46	ischemic fasciitis	9.9	CD68 CDKN2A
47	vulval paget's disease	9.9	CD86 CDKN2A CEACAM5
48	vulva adenocarcinoma	9.9	CD86 CDKN2A CEACAM5
49	liposarcoma	9.9	CALB2 CDKN2A
50	meningeal melanocytoma	9.9	CD68 CDKN2A

Graphical network of the top 20 diseases related to Lymphohistiocytoid Mesothelioma:

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Symptoms & Phenotypes for Lymphohistiocytoid Mesothelioma

MGI Mouse Phenotypes related to Lymphohistiocytoid Mesothelioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	9.43	CD68 CD86 CDKN2A EPCAM PTGER4 THBD
2	immune system	MP:0005387	9.1	CD68 CD86 CDKN2A EPCAM PTGER4 THBD

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Drugs & Therapeutics for Lymphohistiocytoid Mesothelioma

Search Clinical Trials , NIH Clinical Center for Lymphohistiocytoid Mesothelioma

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Genetic Tests for Lymphohistiocytoid Mesothelioma

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Anatomical Context for Lymphohistiocytoid Mesothelioma

MalaCards organs/tissues related to Lymphohistiocytoid Mesothelioma:

⁴¹

Lung, Kidney, Liver, Bone, Pancreas, Testis, Thymus

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Publications for Lymphohistiocytoid Mesothelioma

Articles related to Lymphohistiocytoid Mesothelioma:

#	Title	Authors	Year
1	A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis. ( 29187476 )		2017
2	Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings. ( 22021116 )		2013
3	Lymphohistiocytoid mesothelioma of the pleura. ( 20618734 )	Kawai T....Nakatani Y.	2010
4	Lymphohistiocytoid mesothelioma: a clinical, immunohistochemical and ultrastructural study of four cases and literature review. ( 15693633 )	Yao D.X....Klimstra D.S.	2004
5	Lymphohistiocytoid mesothelioma. An often misdiagnosed variant of sarcomatoid malignant mesothelioma. ( 10800396 )	Khalidi H.S....Battifora H.	2000
6	Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma. ( 2458647 )	Henderson D.W....Steele R.H.	1988

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Genes for Lymphohistiocytoid Mesothelioma

Genes related to Lymphohistiocytoid Mesothelioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	THBD	Thrombomodulin	Protein Coding	21.28	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	CD86	CD86 Molecule	Protein Coding	14.81	DISEASES inferred ¹⁵
3	PTGER4	Prostaglandin E Receptor 4	Protein Coding	14.56	DISEASES inferred ¹⁵
4	EPCAM	Epithelial Cell Adhesion Molecule	Protein Coding	14.01	DISEASES inferred ¹⁵
5	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	13.14	DISEASES inferred ¹⁵
6	CALB2	Calbindin 2	Protein Coding	13.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	CD68	CD68 Molecule	Protein Coding	3.58	DISEASES inferred ¹⁵
8	CEACAM5	Carcinoembryonic Antigen Related Cell Adhesion Molecule 5	Protein Coding	3.18	DISEASES inferred ¹⁵

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Variations for Lymphohistiocytoid Mesothelioma

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Expression for Lymphohistiocytoid Mesothelioma

Search GEO for disease gene expression data for Lymphohistiocytoid Mesothelioma.

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Pathways for Lymphohistiocytoid Mesothelioma

Pathways related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cell surface interactions at the vascular wall ⁶⁶ Show member pathways Fibronectin matrix formation ⁶⁶ PECAM1 interactions ⁶⁶ Tie2 Signaling ⁶⁶	11.38	CEACAM5 EPCAM THBD
2	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.13	EPCAM THBD
3	Microglia Activation During Neuroinflammation: Microglia Polarization ⁶⁵	11.01	CD68 CD86
4	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	10.86	CD68 CD86 CEACAM5

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GO Terms for Lymphohistiocytoid Mesothelioma

Cellular components related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell surface	GO:0009986	8.92	CD86 CEACAM5 EPCAM THBD

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Sources for Lymphohistiocytoid Mesothelioma

¹ BioSystems

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²⁷ GEO DataSets

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³³ ICD10

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³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

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⁴⁸ NCBI Bookshelf

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⁵⁵ Novoseek

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⁵⁷ OMIM

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⁶⁸ SNOMED-CT

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⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia