Lymphohistiocytoid Mesothelioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lymphohistiocytoid Mesothelioma

MalaCards integrated aliases for Lymphohistiocytoid Mesothelioma:

Name: Lymphohistiocytoid Mesothelioma ¹² ¹⁵ ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7381

NCIt ⁵⁰ C27779

UMLS ⁷³ C1334464

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Summaries for Lymphohistiocytoid Mesothelioma

MalaCards based summary : Lymphohistiocytoid Mesothelioma is related to sarcomatoid mesothelioma and adenomatoid tumor. An important gene associated with Lymphohistiocytoid Mesothelioma is THBD (Thrombomodulin), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Dendritic Cells Developmental Lineage Pathway. Related phenotypes are hematopoietic system and immune system

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Related Diseases for Lymphohistiocytoid Mesothelioma

Diseases related to Lymphohistiocytoid Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)

#	Related Disease	Score	Top Affiliating Genes
1	sarcomatoid mesothelioma	30.5	CDKN2A THBD
2	adenomatoid tumor	10.6	CALB2 THBD
3	malignant epithelial mesothelioma	10.5	PTGER4 THBD
4	papillary thymic adenocarcinoma	10.5	CALB2 PTGER4
5	benign mesothelioma	10.5	CALB2 THBD
6	lung sarcoma	10.5	CALB2 THBD
7	cervix endometriosis	10.4	CALB2 CEACAM5
8	bile duct cystadenocarcinoma	10.4	CALB2 CEACAM5
9	ovarian brenner tumor	10.4	CALB2 THBD
10	gallbladder squamous cell carcinoma	10.4	CD86 CEACAM5
11	mucinous ovarian cystadenoma	10.4	CALB2 CEACAM5
12	spermatocele	10.3	CALB2 CEACAM5
13	nodular hidradenoma	10.3	CEACAM5 PTGER4
14	fallopian tube endometrioid adenocarcinoma	10.3	CALB2 CDKN2A
15	malignant pleural mesothelioma	10.3	CALB2 THBD
16	mucinous bronchioloalveolar adenocarcinoma	10.3	CALB2 CDKN2A
17	thymus adenocarcinoma	10.3	CEACAM5 PTGER4
18	pancreatic mucinous cystadenoma	10.3	CALB2 CEACAM5
19	mixed ductal-endocrine carcinoma	10.3	CALB2 CEACAM5
20	pericardial tuberculosis	10.3	CEACAM5 PTGER4
21	skin carcinoma in situ	10.3	CD86 CDKN2A
22	bartholin's gland benign neoplasm	10.2	CD86 CDKN2A
23	pleural cancer	10.2	CALB2 CDKN2A
24	peritoneal mesothelioma	10.2	CDKN2A THBD
25	chondroid chordoma	10.2	CEACAM5 EPCAM
26	polycystic liver disease 1 with or without kidney cysts	10.1	CALB2 CEACAM5
27	pericardium cancer	10.1	CALB2 PTGER4 THBD
28	pericardial mesothelioma	10.1	CALB2 PTGER4 THBD
29	adenoid basal cell carcinoma	10.1	CDKN2A CEACAM5
30	cervical clear cell adenocarcinoma	10.0	CDKN2A CEACAM5
31	bile duct adenocarcinoma	10.0	CEACAM5 EPCAM
32	pneumatosis cystoides intestinalis	10.0	CALB2 CD68
33	pleomorphic lipoma	9.9	CALB2 CD68
34	mesothelioma, malignant	9.9	CALB2 CDKN2A THBD
35	gastrointestinal system benign neoplasm	9.9	CDKN2A CEACAM5
36	fox-fordyce disease	9.9	CD68 CEACAM5
37	liposarcoma	9.9	CALB2 CDKN2A
38	epididymis cancer	9.9	CD86 CEACAM5 PTGER4
39	epididymis adenocarcinoma	9.9	CD86 CEACAM5 PTGER4
40	miliaria	9.8	CD68 CEACAM5
41	liver sarcoma	9.8	CD68 CEACAM5
42	cell type benign neoplasm	9.8	CDKN2A CEACAM5
43	chondroid lipoma	9.8	CD68 CEACAM5
44	clear cell acanthoma	9.8	CD68 CEACAM5
45	congenital epulis	9.8	CD68 CEACAM5
46	female reproductive organ cancer	9.8	CDKN2A CEACAM5
47	melanomatosis	9.8	CD68 CDKN2A
48	bladder carcinoma in situ	9.7	CD68 CDKN2A
49	conventional leiomyosarcoma	9.7	CD68 CDKN2A
50	xanthogranulomatous cholecystitis	9.7	CD68 CEACAM5

Graphical network of the top 20 diseases related to Lymphohistiocytoid Mesothelioma:

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Symptoms & Phenotypes for Lymphohistiocytoid Mesothelioma

MGI Mouse Phenotypes related to Lymphohistiocytoid Mesothelioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	9.43	CD68 CD86 CDKN2A EPCAM PTGER4 THBD
2	immune system	MP:0005387	9.1	CD68 CD86 CDKN2A EPCAM PTGER4 THBD

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Drugs & Therapeutics for Lymphohistiocytoid Mesothelioma

Search Clinical Trials , NIH Clinical Center for Lymphohistiocytoid Mesothelioma

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Genetic Tests for Lymphohistiocytoid Mesothelioma

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Anatomical Context for Lymphohistiocytoid Mesothelioma

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Publications for Lymphohistiocytoid Mesothelioma

Articles related to Lymphohistiocytoid Mesothelioma:

#	Title	Authors	Year
1	A Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis. ( 29187476 )	Matsubara T....Maehara Y.	2017
2	Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings. ( 22021116 )	Tresserra F....Ramos C.	2013
3	Lymphohistiocytoid mesothelioma of the pleura. ( 20618734 )	Kawai T....Nakatani Y.	2010
4	Lymphohistiocytoid mesothelioma: a clinical, immunohistochemical and ultrastructural study of four cases and literature review. ( 15693633 )	Yao D.X....Klimstra D.S.	2004
5	Lymphohistiocytoid mesothelioma. An often misdiagnosed variant of sarcomatoid malignant mesothelioma. ( 10800396 )	Khalidi H.S....Battifora H.	2000
6	Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma. ( 2458647 )	Henderson D.W....Steele R.H.	1988

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Genes for Lymphohistiocytoid Mesothelioma

Genes related to Lymphohistiocytoid Mesothelioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	THBD	Thrombomodulin	Protein Coding	21.43	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	CD86	CD86 Molecule	Protein Coding	14.92	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	PTGER4	Prostaglandin E Receptor 4	Protein Coding	14.67	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	EPCAM	Epithelial Cell Adhesion Molecule	Protein Coding	14.2	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	13.29	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	CALB2	Calbindin 2	Protein Coding	13.27	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	CD68	CD68 Molecule	Protein Coding	3.67	DISEASES inferred ¹⁵
8	CEACAM5	Carcinoembryonic Antigen Related Cell Adhesion Molecule 5	Protein Coding	3.34	DISEASES inferred ¹⁵

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Variations for Lymphohistiocytoid Mesothelioma

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Expression for Lymphohistiocytoid Mesothelioma

Search GEO for disease gene expression data for Lymphohistiocytoid Mesothelioma.

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Pathways for Lymphohistiocytoid Mesothelioma

Pathways related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cell surface interactions at the vascular wall ⁶⁶ Show member pathways Fibronectin matrix formation ⁶⁶ PECAM1 interactions ⁶⁶ Tie2 Signaling ⁶⁶	11.38	CEACAM5 EPCAM THBD
2	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.02	EPCAM THBD
3	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	10.86	CD68 CD86 CEACAM5

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GO Terms for Lymphohistiocytoid Mesothelioma

Biological processes related to Lymphohistiocytoid Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	leukocyte migration	GO:0050900	8.8	CEACAM5 EPCAM THBD

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Sources for Lymphohistiocytoid Mesothelioma

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⁷¹ TGDB

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⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia