EC1
MCID: LYS023
MIFTS: 15

Lysis by Alloreactive Natural Killer Cells (EC1)

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Aliases & Classifications for Lysis by Alloreactive Natural Killer Cells

MalaCards integrated aliases for Lysis by Alloreactive Natural Killer Cells:

Name: Lysis by Alloreactive Natural Killer Cells 57
Lysis by Alloreactive Natural Killer Cells, Susceptibility to 57
Susceptibility to Lysis by Alloreactive Natural Killer Cells 57
Natural Killer Cell Susceptibility 1 57
Nks1 57
Ec1 57

Characteristics:


Inheritance:

Autosomal recessive 57

External Ids:

OMIM® 57 272370

Summaries for Lysis by Alloreactive Natural Killer Cells

OMIM®: 57 Susceptibility to lysis by alloreactive natural killer (NK) cells is an autosomal recessive trait (thus differing from the behavior of conventional MHC products) (Ciccone et al., 1990; Ciccone et al., 1990). (272370) (Updated 08-Dec-2022)

MalaCards based summary: Lysis by Alloreactive Natural Killer Cells, also known as lysis by alloreactive natural killer cells, susceptibility to, is related to esophageal cancer and pemphigus vulgaris, familial. An important gene associated with Lysis by Alloreactive Natural Killer Cells is NKS1 (Natural Killer Cell Susceptibility 1). Affiliated tissues include nk cells, and related phenotype is abnormality of the immune system.

Related Diseases for Lysis by Alloreactive Natural Killer Cells

Graphical network of the top 20 diseases related to Lysis by Alloreactive Natural Killer Cells:



Diseases related to Lysis by Alloreactive Natural Killer Cells

Symptoms & Phenotypes for Lysis by Alloreactive Natural Killer Cells

Human phenotypes related to Lysis by Alloreactive Natural Killer Cells:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of the immune system 30 HP:0002715

Symptoms via clinical synopsis from OMIM®:

57 (Updated 08-Dec-2022)
Immunology:
alloreactive natural killer cell lysis susceptibility

Clinical features from OMIM®:

272370 (Updated 08-Dec-2022)

Drugs & Therapeutics for Lysis by Alloreactive Natural Killer Cells

Search Clinical Trials, NIH Clinical Center for Lysis by Alloreactive Natural Killer Cells

Genetic Tests for Lysis by Alloreactive Natural Killer Cells

Anatomical Context for Lysis by Alloreactive Natural Killer Cells

Organs/tissues related to Lysis by Alloreactive Natural Killer Cells:

MalaCards : Nk Cells

Publications for Lysis by Alloreactive Natural Killer Cells

Articles related to Lysis by Alloreactive Natural Killer Cells:

# Title Authors PMID Year
1
Susceptibility or resistance to lysis by alloreactive natural killer cells is governed by a gene in the human major histocompatibility complex between BF and HLA-B. 62 57
1979875 1990
2
Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells. 57
1694227 1990
3
NKS1, Na(+)- and K(+)-sensitive 1, regulates ion homeostasis in an SOS-independent pathway in Arabidopsis. 62
21227472 2011
4
Generation of "natural killer cell-escape" variants of Pichinde virus during acute and persistent infections. 62
1372371 1992

Variations for Lysis by Alloreactive Natural Killer Cells

Expression for Lysis by Alloreactive Natural Killer Cells

Search GEO for disease gene expression data for Lysis by Alloreactive Natural Killer Cells.

Pathways for Lysis by Alloreactive Natural Killer Cells

GO Terms for Lysis by Alloreactive Natural Killer Cells

Sources for Lysis by Alloreactive Natural Killer Cells

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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