Macroglobulinemia, Waldenstrom 2 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Macroglobulinemia, Waldenstrom 2

MalaCards integrated aliases for Macroglobulinemia, Waldenstrom 2:

Name: Macroglobulinemia, Waldenstrom 2 ⁵⁷

Macroglobulinemia, Waldenstrom, Susceptibility to, 2 ⁵⁷ ¹³

Wm2 ⁵⁷

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases Blood diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁷ 610430

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Summaries for Macroglobulinemia, Waldenstrom 2

MalaCards based summary : Macroglobulinemia, Waldenstrom 2, also known as macroglobulinemia, waldenstrom, susceptibility to, 2, is related to waldenstrom macroglobulinemia. An important gene associated with Macroglobulinemia, Waldenstrom 2 is WM2 (Macroglobulinemia, Waldenstrom, Susceptibility To, 2). The drugs Bortezomib and Dexamethasone have been mentioned in the context of this disorder.

Description from OMIM: 610430

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Related Diseases for Macroglobulinemia, Waldenstrom 2

Diseases in the Waldenstrom Macroglobulinemia family:

Macroglobulinemia, Waldenstrom 1

Macroglobulinemia, Waldenstrom 2

Diseases related to Macroglobulinemia, Waldenstrom 2 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	waldenstrom macroglobulinemia	10.9

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Symptoms & Phenotypes for Macroglobulinemia, Waldenstrom 2

Clinical features from OMIM:

610430

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Drugs & Therapeutics for Macroglobulinemia, Waldenstrom 2

Drugs for Macroglobulinemia, Waldenstrom 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Bortezomib

Approved, Investigational

Phase 2

179324-69-7

387447 93860

Synonyms:

[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid

[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid

179324-69-7

341, PS

AC1L8TUW

bortezomib

Bortezomib

Bortezomib (JAN/USAN/INN)

CHEBI:287372

CHEBI:41143

CHEMBL325041

CID387447

D03150

DB07475

DPBA

FT-0082488

I14-3268

LDP 341

LDP341

LDP-341

LPD 341

LPD-341

MLN341

MolPort-003-845-298

N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide

N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide

N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE

NCI60_029010

NSC681239

NSC-681239

PROSCRIPT BORONIC ACID

PS 341

PS-341

Pyz-Phe-boroLeu

S1013_Selleck

SBB071337

Velcade

Velcade (TN)

Velcade, MG-341, PS-341, Bortezomib

2

Dexamethasone

Approved, Investigational, Vet_approved

Phase 2

50-02-2

5743

Synonyms:

(3H)-Dexamethasone

.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol

.gamma.corten

137098-19-2

16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol

16.alpha.-Methyl-9.alpha.-fluoroprednisolone

16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol

16alpha -Methyl-9alpha -fluoroprednisolone

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol

16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone

16alpha-Methyl-9alpha-fluoroprednisolone

16-alpha-Methyl-9-alpha-fluoroprednisolone

16a-Methyl-9a-fluoro-1-dehydrocortisol

16α-methyl-9α-fluoro-1-dehydrocortisol

16α-Methyl-9α-fluoro-1-dehydrocortisol

1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone

1-dehydro-16alpha -Methyl-9alpha -fluorohydrocortisone

1-dehydro-16alpha-Methyl-9alpha-fluorohydrocortisone

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

1-dehydro-16a-Methyl-9a-fluorohydrocortisone

1-dehydro-16α-methyl-9α-fluorohydrocortisone

1-Dehydro-16α-methyl-9α-fluorohydrocortisone

23495-06-9

31375_FLUKA

46165_FLUKA

46165_RIEDEL

50-02-2

8054-59-9

9.alpha.-Fluoro-16.alpha.-methylprednisolone

906422-84-2

9a-fluoro-16a-Methylprednisolone

9a-fluoro-16BETA-METHYLPREDNISOLONE

9A-FLUORO-16BETA-METHYLPREDNISOLONE

9alpha -fluoro-16alpha -Methylprednisolone

9alpha-fluoro-16alpha-Methylprednisolone

9alpha-fluoro-16alpha-Methyl-prednisolone

9-alpha-fluoro-16-alpha-Methylprednisolone

9alpha-Fluoro-16alpha-methylprednisolone

9-alpha-Fluoro-16-alpha-methylprednisolone

9-fluoro-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione

9-fluoro-11alpha -Methylpregna-1,4-diene-3,20-dione

9-fluoro-16-Methylprednisolone

9α-fluoro-16α-methylprednisolone

9α-Fluoro-16α-methylprednisolone

AC-11056

AC1L1L1H

AC1Q29DM

Adexone

Aeroseb-D

Aeroseb-dex

Aeroseb-Dex

AI3-50934

Ak dex OPH otic soln 0.1%

Alcon brand OF dexamethasone

Alcon Brand of Dexamethasone

alpha -fluoro-16-alpha -Methylcortisol

Anaflogistico

Aphtasolon

Aphthasolone

apo-Dexamethasone

Auxiron

Azimycin (veterinary)

Azium

Azium (veterinary)

Azium (Veterinary)

BIDD:ER0494

BIDD:PXR0060

Bisu Ds

Bisu DS

BRD-K38775274-001-02-3

BRD-K38775274-001-06-4

BSPBio_000995

C15643

C22H29FO5

Calonat

CCRIS 7067

CHEBI:41879

CHEMBL384467

CID5743

Corson

Corsone

Cortisumman

CPD001227192

CPD-10549

D00292

D003907

D1756_SIGMA

D4902_SIGMA

D6645_SIGMA

D8893_SIGMA

D9184_SIGMA

DB01234

Decacort

Decacortin

Decaderm

Decadron

Decadron (TN)

Decadron Tablets, Elixir

Decadron, Dexamethasone

Decadron-La

Decadron-LA

Decagel

Decaject

Decaject l.a.

Decaject L.A.

Decaject-l.a.

Decaject-L.A.

Decalix

Decameth

Decasone

Decaspray

Dectancyl

Dekacort

delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol

delta1-9alpha-Fluoro-16alpha-methylcortisol

Delta1-9alpha-fluoro-16alpha-Methylcortisol

Deltafluorene

Dergramin

Deronil

Desadrene

Desametasone

Desametasone [Dcit]

Desametasone [DCIT]

Desamethasone

Desameton

Deseronil

DEX

Dexa

DEXA

Dexa mamallet

Dexa Mamallet

Dexacen-4

Dexacidin

Dexacort

Dexacortal

Dexa-cortidelt

Dexa-Cortidelt

Dexacortin

Dexa-cortisyl

Dexa-Cortisyl

Dexadeltone

Dexafarma

Dexair

Dexalona

Dexaltin

Dexa-Mamallet

Dexametasona

Dexametasona [INN-Spanish]

Dexametasone

Dexameth

Dexamethansone

dexamethasone

Dexamethasone

Dexamethasone (JP15/USP/INN)

Dexamethasone [INN:BAN:JAN]

Dexamethasone acetate

Dexamethasone Acetate

Dexamethasone alcohol

Dexamethasone Alcohol

Dexamethasone base

Dexamethasone Base

Dexamethasone intensol

Dexamethasone Intensol

Dexamethasone sodium phosphate

Dexamethasone Sodium Phosphate

Dexamethasone-omega

Dexamethasonum

Dexamethasonum [INN-Latin]

Dexamethazone

Dexamonozon

Dexapolcort

Dexapos

Dexaprol

Dexa-scheroson

Dexa-Scheroson

Dexa-sine

Dexa-Sine

Dexason

Dexasone

Dexasone 0.5MG

Dexasone 0.75MG

Dexasone 4MG

Dexasporin

Dex-ide

Dex-Ide

Dexinolon

Dexinoral

Dexone

Dexone 0.5

DEXONE 0.5

Dexone 0.75

DEXONE 0.75

Dexone 1.5

DEXONE 1.5

Dexone 4

DEXONE 4

Dexonium

Dexpak

Dextelan

Dezone

Dinormon

DXM

Dxms

DXMS

ECR brand OF dexamethasone

ECR Brand of Dexamethasone

EINECS 200-003-9

Fluormethylprednisolone

Fluormone

Fluorocort

Fortecortin

Foy brand OF dexamethasone

Foy Brand of Dexamethasone

FT-0080377

Gammacorten

Hexadecadrol

Hexadrol

Hexadrol elixir

Hexadrol Elixir

Hexadrol Tablets

Hl-dex

Hl-Dex

HL-Dex

HMS1792A17

HMS1990A17

HMS2089N13

HSDB 3053

I06-1196

ICN brand OF dexamethasone

ICN Brand of Dexamethasone

IontoDex

isopto-Dex

Isopto-Dex

Lokalison F

Loverine

LS-7300

Luxazone

Maxidex

Maxidex ont 0.1%

Maxidex sus 0.1%

Maxitrol

Mediamethasone

Merck brand OF dexamethasone

Merck Brand of Dexamethasone

Merz brand 1 OF dexamethasone

Merz Brand 1 of Dexamethasone

Merz brand 2 OF dexamethasone

Merz Brand 2 of Dexamethasone

Methylfluorprednisolone

Mexidex

Millicorten

MK 125

MLS001055412

MLS001332507

MLS001332508

MolMap_000018

MolPort-003-846-433

Mymethasone

Naquasone (veterinary)

NCGC00091019-01

NCGC00091019-02

NCGC00091019-03

NCGC00091019-04

NCGC00091019-05

nchembio809-comp2

NCI60_003067

Neomycin and polymyxin b sulfates and dexamethasone

Neomycin and polymyxin b sulphates and dexamethasone

NSC 34521

NSC34521

Ocu-trol

Ocu-Trol

Oradexon

OTO-104

Pet derm III

Pet Derm Iii

Pet Derm III

Pet-Derm Iii

PHL-Dexamethasone

PMS Dexamethasone elixir 0.5mg/5ML

PMS-Dexamethasone

Policort

Posurdex

Prednisolon F

Prednisolone F

Prodex

S1322_Selleck

SAM002548948

Sandoz dexamethasone

SGCUT00126

Sk-Dexamethasone

SK-Dexamethasone

SMP1_000092

SMR000857119

SMR001227192

Spectrum5_002019

Spoloven

ST50307091

Sunia sol D

Sunia Sol D

Superprednol

TL8003317

to_000038

Tobradex

Tobramycin and dexamethasone

Tresaderm (veterinary)

Turbinaire

UNII-7S5I7G3JQL

Visumetazone

WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1

ZINC03875332

3

BB 1101

Phase 2

4

Dexamethasone acetate

Phase 2

1177-87-3

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Efficacy of Bortezomib (Velcade(R)) in Patients With Advanced Waldenström Macroglobulinemia	Completed	NCT00777738	Phase 2	BORTEZOMIB

Search NIH Clinical Center for Macroglobulinemia, Waldenstrom 2

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Genetic Tests for Macroglobulinemia, Waldenstrom 2

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Anatomical Context for Macroglobulinemia, Waldenstrom 2

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Publications for Macroglobulinemia, Waldenstrom 2

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Genes for Macroglobulinemia, Waldenstrom 2

Genes related to Macroglobulinemia, Waldenstrom 2 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	WM2	Macroglobulinemia, Waldenstrom, Susceptibility To, 2	Genetic Locus	50	Susceptibility factor ⁵⁷

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Variations for Macroglobulinemia, Waldenstrom 2

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Expression for Macroglobulinemia, Waldenstrom 2

Search GEO for disease gene expression data for Macroglobulinemia, Waldenstrom 2.

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Pathways for Macroglobulinemia, Waldenstrom 2

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GO Terms for Macroglobulinemia, Waldenstrom 2

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