MCID: MJR006
MIFTS: 29

Major Affective Disorder 5

Categories: Mental diseases, Genetic diseases

Aliases & Classifications for Major Affective Disorder 5

MalaCards integrated aliases for Major Affective Disorder 5:

Name: Major Affective Disorder 5 57 13 73
Bipolar Affective Disorder; Bpad 57
Bipolar Affective Disorder 57
Bipolar Disorder 73
Mafd5 57
Bpad 57

Classifications:



External Ids:

OMIM 57 611535
MedGen 42 C1970944
UMLS 73 C1970944

Summaries for Major Affective Disorder 5

MalaCards based summary : Major Affective Disorder 5, also known as bipolar affective disorder; bpad, is related to major affective disorder 1 and major affective disorder 2. An important gene associated with Major Affective Disorder 5 is MAFD5 (Major Affective Disorder 5). Affiliated tissues include brain, testes and cortex.

Description from OMIM: 611535

Related Diseases for Major Affective Disorder 5

Diseases in the Major Affective Disorder 7 family:

Major Affective Disorder 1 Major Affective Disorder 2
Major Affective Disorder 3 Major Affective Disorder 4
Major Affective Disorder 5 Major Affective Disorder 6
Major Affective Disorder 8 Major Affective Disorder 9

Diseases related to Major Affective Disorder 5 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 major affective disorder 1 11.5
2 major affective disorder 2 11.5
3 major affective disorder 4 11.5
4 major affective disorder 6 11.5
5 bipolar disorder 10.9

Graphical network of the top 20 diseases related to Major Affective Disorder 5:



Diseases related to Major Affective Disorder 5

Symptoms & Phenotypes for Major Affective Disorder 5

Clinical features from OMIM:

611535

Drugs & Therapeutics for Major Affective Disorder 5

Genetic Tests for Major Affective Disorder 5

Anatomical Context for Major Affective Disorder 5

MalaCards organs/tissues related to Major Affective Disorder 5:

41
Brain, Testes, Cortex, Amygdala, Ovary, Prefrontal Cortex

Publications for Major Affective Disorder 5

Articles related to Major Affective Disorder 5:

(show top 50) (show all 257)
# Title Authors Year
1
Polycystic Ovary Syndrome in Bipolar Affective Disorder: A Hospital-based Study. ( 29962567 )
2018
2
Polydipsia as a Precursor of Manic Episode in Bipolar Affective Disorder Patients with Alcohol Use Disorder. ( 29397674 )
2018
3
A Rare Presentation of a Case of Obsessive-compulsive Disorder Comorbid with Bipolar Affective Disorder. ( 29284814 )
2017
4
Predictors of rehospitalization in a naturalistic cohort of patients with bipolar affective disorder. ( 28207568 )
2017
5
Soluble Intracellular Adhesion Molecule-1 in Patients with Unipolar or Bipolar Affective Disorders: Results from a Pilot Trial. ( 27442531 )
2016
6
DGKH genetic risk variant influences gene expression in bipolar affective disorder. ( 27016658 )
2016
7
Comparative neuropsychiatry: white matter abnormalities in children and adolescents with schizophrenia, bipolar affective disorder, and obsessive-compulsive disorder. ( 25498242 )
2015
8
Frontotemporal dementia mimicking bipolar affective disorder, normal pressure hydrocephalus and KlA1ver-Bucy syndrome. ( 26482719 )
2015
9
Influence of DGKH variants on amygdala volume in patients with bipolar affective disorder and schizophrenia. ( 24958494 )
2015
10
Fluctuating capacity and advance decision-making in Bipolar Affective Disorder - Self-binding directives and self-determination. ( 25939286 )
2015
11
Pharmacotherapy of Bipolar Affective Disorder: A Hospital based Study from Sub Himalayan Valley of Nepal. ( 25121003 )
2014
12
Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder. ( 25311364 )
2014
13
Brain-derived neurotrophic factor (BDNF)-epigenetic regulation in unipolar and bipolar affective disorder. ( 25106037 )
2014
14
De novo CNVs in bipolar affective disorder and schizophrenia. ( 25055870 )
2014
15
Analysis of genetic association and epistasis interactions between circadian clock genes and symptom dimensions of bipolar affective disorder. ( 24673294 )
2014
16
Association analysis of genes in serotonin pathway with attention and executive function in patients with bipolar affective disorder. ( 25200194 )
2014
17
Olanzapine-induced neuroleptic malignant syndrome in a patient with bipolar affective disorder: Does quetiapine holds the solution? ( 25013321 )
2013
18
Contribution of methotrexate in precipitation of manic episode in bipolar affective disorder explored: a case report. ( 24167698 )
2013
19
Can we prevent under-diagnosis and misdiagnosis of bipolar affective disorder? Repeat audits to assess the epidemiological change in the caseload of a community mental health team when bipolar disorder is accurately assessed and diagnosed. ( 23995161 )
2013
20
[Cognitive functioning in depression and the course of bipolar affective disorder]. ( 23888758 )
2013
21
No association between serum cholesterol and death by suicide in patients with schizophrenia, bipolar affective disorder, or major depressive disorder. ( 24308827 )
2013
22
Bipolar affective disorder preceding frontotemporal dementia in a patient with C9ORF72 mutation: is there a genetic link between these two disorders? ( 23314407 )
2013
23
A case of bipolar affective disorder and aspiration pneumonia. ( 23956911 )
2013
24
Sodium Valproate induced priapism in an adult with bipolar affective disorder. ( 24347777 )
2013
25
Mental state deterioration after switching from brand-name to generic olanzapine in an adolescent with bipolar affective disorder, autism and intellectual disability: a case study. ( 24094081 )
2013
26
Bipolar affective disorder and early dementia onset in a male patient with SHANK3 deletion. ( 22922660 )
2012
27
Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study. ( 22832903 )
2012
28
A follow-up study of family burden in patients with bipolar affective disorder. ( 21421638 )
2012
29
Borderline personality disorder and bipolar affective disorder. Spectra or spectre? A review. ( 22508593 )
2012
30
Analysis of association between common SNPs in ErbB4 and bipolar affective disorder, major depressive disorder and schizophrenia in the Han Chinese population. ( 21993442 )
2012
31
Differential diagnosis of bipolar affective disorder type II and borderline personality disorder: analysis of the affective dimension. ( 22560773 )
2012
32
Tests of linkage and allelic association between markers in the 1p36 PRKCZ (protein kinase C zeta) gene region and bipolar affective disorder. ( 22231931 )
2012
33
Quinacrine induced mood disturbance--the unmasking of bipolar affective disorder. ( 22729334 )
2012
34
Gender-specific association of TSNAX/DISC1 locus for schizophrenia and bipolar affective disorder in South Indian population. ( 22673686 )
2012
35
Carbamazepine-induced erythema multiforme major in an epileptic patient with bipolar affective disorder. ( 22629103 )
2012
36
Haloperidol induced obsessive compulsive symptom (OCS) in a patient with learning disability and bipolar affective disorder. ( 22605593 )
2012
37
Atypical presentation of tardive dyskinesia associated with risperidone long-acting injection as maintenance treatment in bipolar affective disorder: a case report. ( 22663952 )
2012
38
Comorbid bipolar affective disorder and obsessive compulsive disorder in childhood: a case study and brief review. ( 23440037 )
2012
39
MAGI1 copy number variation in bipolar affective disorder and schizophrenia. ( 22381734 )
2012
40
Development of frontotemporal dementia in a case of bipolar affective disorder: is there a link? ( 22714610 )
2011
41
Cognitions in bipolar affective disorder and unipolar depression: imagining suicide. ( 22085478 )
2011
42
Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder. ( 21302346 )
2011
43
Chronic somatic comorbidity and excess mortality due to natural causes in persons with schizophrenia or bipolar affective disorder. ( 21935426 )
2011
44
The seasonality of bipolar affective disorder: comparison with a primary care sample using the Seasonal Pattern Assessment Questionnaire. ( 21377212 )
2011
45
A systematic association mapping on chromosome 6q in bipolar affective disorder--evidence for the melanin-concentrating-hormone-receptor-2 gene as a risk factor for bipolar affective disorder. ( 19927306 )
2010
46
Nuclear receptor rev-erb-{alpha} circadian gene variants and lithium carbonate prophylaxis in bipolar affective disorder. ( 20348464 )
2010
47
Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3. ( 20410851 )
2010
48
Effect of fasting during Ramadan on serum lithium level and mental state in bipolar affective disorder. ( 20827213 )
2010
49
Midline brain abnormalities in established bipolar affective disorder. ( 19782407 )
2010
50
Autonomic nervous system in euthymic patients with bipolar affective disorder. ( 21196931 )
2010

Variations for Major Affective Disorder 5

Expression for Major Affective Disorder 5

Search GEO for disease gene expression data for Major Affective Disorder 5.

Pathways for Major Affective Disorder 5

GO Terms for Major Affective Disorder 5

Sources for Major Affective Disorder 5

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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