MDD1
MCID: MJR013
MIFTS: 14

Major Depressive Disorder 1 (MDD1)

Categories: Genetic diseases, Mental diseases, Neuronal diseases

Aliases & Classifications for Major Depressive Disorder 1

MalaCards integrated aliases for Major Depressive Disorder 1:

Name: Major Depressive Disorder 1 57 29 70
Unipolar Depression 1 57
Mdd1 57

Classifications:



External Ids:

OMIM® 57 608520
UMLS 70 C1837929

Summaries for Major Depressive Disorder 1

MalaCards based summary : Major Depressive Disorder 1, also known as unipolar depression 1, is related to major depressive disorder. An important gene associated with Major Depressive Disorder 1 is MDD1 (Major Depressive Disorder). The drugs Psychotropic Drugs and Antidepressive Agents have been mentioned in the context of this disorder.

More information from OMIM: 608520

Related Diseases for Major Depressive Disorder 1

Diseases in the Major Depressive Disorder family:

Major Depressive Disorder 1 Major Depressive Disorder 2

Diseases related to Major Depressive Disorder 1 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 major depressive disorder 11.5

Symptoms & Phenotypes for Major Depressive Disorder 1

Clinical features from OMIM®:

608520 (Updated 20-May-2021)

Drugs & Therapeutics for Major Depressive Disorder 1

Drugs for Major Depressive Disorder 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Psychotropic Drugs
2 Antidepressive Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Major Depressive Disorder Post Stroke With Transcranial Direct Current Stimulation (TDCS): Randomized, Double-Blind, Clinical Trial Completed NCT01525524 Phase 2
2 Evaluation of Pharmacogenetic Testing In a Mental Health Population and Economic Outcomes Completed NCT02474680

Search NIH Clinical Center for Major Depressive Disorder 1

Genetic Tests for Major Depressive Disorder 1

Genetic tests related to Major Depressive Disorder 1:

# Genetic test Affiliating Genes
1 Major Depressive Disorder 1 29

Anatomical Context for Major Depressive Disorder 1

Publications for Major Depressive Disorder 1

Articles related to Major Depressive Disorder 1:

(show all 11)
# Title Authors PMID Year
1
The neuronal transporter gene SLC6A15 confers risk to major depression. 57
21521612 2011
2
Variants in Apaf-1 segregating with major depression promote apoptosome function. 57
16231040 2006
3
Predisposition locus for major depression at chromosome 12q22-12q23.2. 57
14606042 2003
4
Misdiagnosis, detection rate, and associated factors of severe psychiatric disorders in specialized psychiatry centers in Ethiopia. 61
33531016 2021
5
Risk Prediction Models in Psychiatry: Toward a New Frontier for the Prevention of Mental Illnesses. 61
27337225 2017
6
The effect of strategies of personal resilience on depression recovery in an Australian cohort: a mixed methods study. 61
24966226 2015
7
The longitudinal course of PTSD among disaster workers deployed to the World Trade Center following the attacks of September 11th. 61
22095774 2011
8
Depression and diabetes among low-income Hispanics: design elements of a socioculturally adapted collaborative care model randomized controlled trial. 61
19860071 2009
9
Incidence of psychiatric side effects during pegylated interferon- alpha retreatment in nonresponder hepatitis C virus-infected patients. 61
17845538 2007
10
Psychiatric comorbidity assessed in Korean children and adolescents who screen positive for Internet addiction. 61
16841632 2006
11
Generalized anxiety disorder in patients with major depression: is DSM-IV's hierarchy correct? 61
12611832 2003

Variations for Major Depressive Disorder 1

Expression for Major Depressive Disorder 1

Search GEO for disease gene expression data for Major Depressive Disorder 1.

Pathways for Major Depressive Disorder 1

GO Terms for Major Depressive Disorder 1

Sources for Major Depressive Disorder 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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