MCID: MLG048
MIFTS: 25

Malignant Acrospiroma

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Skin diseases

Aliases & Classifications for Malignant Acrospiroma

MalaCards integrated aliases for Malignant Acrospiroma:

Name: Malignant Acrospiroma 12 15
Eccrine Ductal Carcinoma 12 73
Eccrine Ductal Carcinoma of Skin 12
Anaplastic Syringoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5570
NCIt 50 C43345
UMLS 73 C1260964

Summaries for Malignant Acrospiroma

MalaCards based summary : Malignant Acrospiroma, also known as eccrine ductal carcinoma, is related to hidradenocarcinoma and eccrine porocarcinoma. An important gene associated with Malignant Acrospiroma is COL2A1 (Collagen Type II Alpha 1 Chain). The drugs Nivolumab and Antibodies, Monoclonal have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and colon.

Wikipedia : 76 A malignant acrospiroma (also known as hidradenocarcinoma, and "Spiradenocarcinoma") is a sweat gland... more...

Related Diseases for Malignant Acrospiroma

Diseases in the Acrospiroma family:

Malignant Acrospiroma

Diseases related to Malignant Acrospiroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 hidradenocarcinoma 11.8
2 eccrine porocarcinoma 11.2
3 acrospiroma 10.4
4 malignant syringoma 10.2
5 cartilage disease 10.1 COL2A1 SMUG1
6 esophageal adenosquamous carcinoma 10.1 CEACAM5 KRT5
7 bile duct mucoepidermoid carcinoma 10.1 CEACAM5 KRT5
8 malignant biphasic mesothelioma 10.1 CEACAM5 KRT5
9 breast adenomyoepithelioma 10.1 CEACAM5 KRT5
10 breast myoepithelial neoplasm 10.1 CEACAM5 KRT5
11 liver lymphoma 10.1 CEACAM5 SMUG1
12 splenic tuberculosis 10.1 CEACAM5 SMUG1
13 gallbladder squamous cell carcinoma 10.1 CEACAM5 SMUG1
14 tolosa-hunt syndrome 10.1 CEACAM5 SMUG1
15 pleural cancer 10.0 KRT5 SMUG1
16 anus cancer 10.0 KRT5 SMUG1
17 eccrine adenocarcinoma 10.0 CEACAM5 SMUG1
18 oropharynx cancer 10.0 KRT5 SMUG1
19 pericardial tuberculosis 10.0 CEACAM5 SMUG1
20 descending colon cancer 10.0 CEACAM5 SMUG1
21 tuberculous peritonitis 10.0 CEACAM5 SMUG1
22 eccrine acrospiroma 10.0
23 large cell carcinoma 10.0 CEACAM5 KRT5
24 squamous cell carcinoma 10.0
25 xanthogranulomatous cholecystitis 10.0 CEACAM5 SMUG1
26 thymus cancer 10.0 KRT5 SMUG1
27 tracheal cancer 10.0 CEACAM5 SMUG1
28 pleural disease 10.0 CEACAM5 SMUG1
29 esophageal disease 10.0 CEACAM5 SMUG1
30 infiltrative basal cell carcinoma 10.0 CEACAM5 CLEC2A
31 rectal neoplasm 10.0 CEACAM5 SMUG1
32 respiratory system cancer 10.0 CEACAM5 SMUG1
33 intestinal disease 10.0 CEACAM5 SMUG1
34 respiratory system disease 10.0 CEACAM5 SMUG1
35 gastrointestinal system cancer 9.9 CEACAM5 SMUG1
36 fibroepithelial basal cell carcinoma 9.9 CEACAM5 PHLDA1
37 aggressive digital papillary adenocarcinoma 9.9 CEACAM5 PHLDA1
38 endocrine gland cancer 9.9 CEACAM5 SMUG1
39 gastrointestinal system disease 9.9 CEACAM5 SMUG1
40 malignant spiradenoma 9.9 CEACAM5 KRT5 SMUG1
41 prostate squamous cell carcinoma 9.9 CEACAM5 KRT5 SMUG1
42 thyroid cancer, nonmedullary, 2 9.9 CEACAM5 SMUG1
43 pancreas adenocarcinoma 9.8 CEACAM5 SMUG1

Graphical network of the top 20 diseases related to Malignant Acrospiroma:



Diseases related to Malignant Acrospiroma

Symptoms & Phenotypes for Malignant Acrospiroma

Drugs & Therapeutics for Malignant Acrospiroma

Drugs for Malignant Acrospiroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nivolumab Approved Phase 2 946414-94-4
2 Antibodies, Monoclonal Phase 2
3 Antibodies Phase 2
4 Immunoglobulins Phase 2
5 Immunologic Factors Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers Recruiting NCT02978625 Phase 2

Search NIH Clinical Center for Malignant Acrospiroma

Genetic Tests for Malignant Acrospiroma

Anatomical Context for Malignant Acrospiroma

MalaCards organs/tissues related to Malignant Acrospiroma:

41
Skin, Liver, Colon, Prostate, Pancreas, Thyroid, Thymus

Publications for Malignant Acrospiroma

Articles related to Malignant Acrospiroma:

(show all 24)
# Title Authors Year
1
Squamoid Eccrine Ductal Carcinoma: An Aggressive Mimicker of Squamous Cell Carcinoma. ( 29979196 )
2018
2
Squamoid eccrine ductal carcinoma. ( 29894529 )
2018
3
Dermoscopy of squamoid eccrine ductal carcinoma: an aid for early diagnosis. ( 30484539 )
2018
4
Malignant acrospiroma: a case report in the era of next generation sequencing. ( 28347286 )
2017
5
Squamoid eccrine ductal carcinoma of the scalp. ( 25752474 )
2016
6
Squamoid Eccrine Ductal Carcinoma: A Clinicopathologic Study of 30 Cases. ( 26796504 )
2016
7
Squamoid eccrine ductal carcinoma. ( 28099603 )
2016
8
Anatomoclinical study of 30 cases of sclerosing sweat duct carcinomas (microcystic adnexal carcinoma, syringomatous carcinoma and squamoid eccrine ductal carcinoma). ( 25873411 )
2015
9
PET/CT imaging of squamoid eccrine ductal carcinoma. ( 25243946 )
2015
10
Squamoid Eccrine Ductal Carcinoma. ( 26171108 )
2015
11
Malignant acrospiroma of chest and abdominal wall treated with chemotherapy. ( 23723491 )
2013
12
Mohs micrographic surgery in the setting of squamoid eccrine ductal carcinoma: addressing a diagnostic and therapeutic challenge. ( 23630640 )
2013
13
Surgical management of recurrent squamoid eccrine ductal carcinoma of the scalp. ( 22801148 )
2012
14
Squamoid eccrine ductal carcinoma of the scalp. ( 23110015 )
2012
15
Squamoid eccrine ductal carcinoma: inappropriate diagnosis. ( 22182240 )
2011
16
Squamoid eccrine ductal carcinoma: a case report and review of the literature. ( 20010402 )
2010
17
"Squamoid eccrine ductal carcinoma": an unusual low-grade case with follicular differentiation. Are these tumors squamoid variants of microcystic adnexal carcinoma? ( 19786851 )
2009
18
Mohs micrographic surgery for squamoid eccrine ductal carcinoma. ( 16416622 )
2005
19
Metastatic malignant acrospiroma of the hand. ( 11417993 )
2001
20
Recurrent malignant acrospiroma. Treatment by chest wall excision. ( 9723060 )
1998
21
Squamoid eccrine ductal carcinoma. ( 9639127 )
1998
22
Squamoid eccrine ductal carcinoma. ( 9088963 )
1997
23
Malignant acrospiroma. ( 2176667 )
1990
24
Sweat gland carcinoma of the hand (malignant acrospiroma). ( 2544641 )
1989

Variations for Malignant Acrospiroma

Expression for Malignant Acrospiroma

Search GEO for disease gene expression data for Malignant Acrospiroma.

Pathways for Malignant Acrospiroma

GO Terms for Malignant Acrospiroma

Sources for Malignant Acrospiroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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