MCID: MLG048
MIFTS: 25

Malignant Acrospiroma

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Skin diseases

Aliases & Classifications for Malignant Acrospiroma

MalaCards integrated aliases for Malignant Acrospiroma:

Name: Malignant Acrospiroma 12 15
Eccrine Ductal Carcinoma 12 74
Eccrine Ductal Carcinoma of Skin 12
Anaplastic Syringoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5570
NCIt 51 C43345
UMLS 74 C1260964

Summaries for Malignant Acrospiroma

MalaCards based summary : Malignant Acrospiroma, also known as eccrine ductal carcinoma, is related to hidradenocarcinoma and eccrine porocarcinoma. An important gene associated with Malignant Acrospiroma is COL2A1 (Collagen Type II Alpha 1 Chain). The drugs nivolumab and Talimogene laherparepvec have been mentioned in the context of this disorder. Affiliated tissues include skin.

Wikipedia : 77 A malignant acrospiroma (also known as hidradenocarcinoma, and "Spiradenocarcinoma") is a sweat gland... more...

Related Diseases for Malignant Acrospiroma

Diseases in the Acrospiroma family:

Malignant Acrospiroma

Diseases related to Malignant Acrospiroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 hidradenocarcinoma 11.8
2 eccrine porocarcinoma 11.2
3 acrospiroma 10.4
4 malignant syringoma 10.2
5 cartilage disease 10.1 COL2A1 SMUG1
6 esophageal adenosquamous carcinoma 10.1 CEACAM5 KRT5
7 bile duct mucoepidermoid carcinoma 10.1 CEACAM5 KRT5
8 malignant biphasic mesothelioma 10.1 CEACAM5 KRT5
9 breast adenomyoepithelioma 10.1 CEACAM5 KRT5
10 liver lymphoma 10.1 CEACAM5 SMUG1
11 breast myoepithelial neoplasm 10.1 CEACAM5 KRT5
12 splenic tuberculosis 10.1 CEACAM5 SMUG1
13 gallbladder squamous cell carcinoma 10.1 CEACAM5 SMUG1
14 tolosa-hunt syndrome 10.1 CEACAM5 SMUG1
15 pleural cancer 10.1 KRT5 SMUG1
16 anus cancer 10.1 KRT5 SMUG1
17 eccrine adenocarcinoma 10.1 CEACAM5 SMUG1
18 pericardial tuberculosis 10.1 CEACAM5 SMUG1
19 oropharynx cancer 10.1 KRT5 SMUG1
20 descending colon cancer 10.1 CEACAM5 SMUG1
21 sweat gland cancer 10.0
22 tuberculous peritonitis 10.0 CEACAM5 SMUG1
23 squamous cell carcinoma 10.0
24 large cell carcinoma 10.0 CEACAM5 KRT5
25 xanthogranulomatous cholecystitis 10.0 CEACAM5 SMUG1
26 thymus cancer 10.0 KRT5 SMUG1
27 tracheal cancer 10.0 CEACAM5 SMUG1
28 pleural disease 10.0 CEACAM5 SMUG1
29 esophageal disease 10.0 CEACAM5 SMUG1
30 infiltrative basal cell carcinoma 10.0 CEACAM5 CLEC2A
31 respiratory system cancer 10.0 CEACAM5 SMUG1
32 intestinal disease 9.9 CEACAM5 SMUG1
33 gastrointestinal system cancer 9.9 CEACAM5 SMUG1
34 respiratory system disease 9.9 CEACAM5 SMUG1
35 fibroepithelial basal cell carcinoma 9.9 CEACAM5 PHLDA1
36 aggressive digital papillary adenocarcinoma 9.9 CEACAM5 PHLDA1
37 endocrine gland cancer 9.9 CEACAM5 SMUG1
38 gastrointestinal system disease 9.8 CEACAM5 SMUG1
39 malignant spiradenoma 9.8 CEACAM5 KRT5 SMUG1
40 prostate squamous cell carcinoma 9.8 CEACAM5 KRT5 SMUG1
41 thyroid cancer, nonmedullary, 2 9.8 CEACAM5 SMUG1
42 pancreas adenocarcinoma 9.7 CEACAM5 SMUG1

Graphical network of the top 20 diseases related to Malignant Acrospiroma:



Diseases related to Malignant Acrospiroma

Symptoms & Phenotypes for Malignant Acrospiroma

Drugs & Therapeutics for Malignant Acrospiroma

Drugs for Malignant Acrospiroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2
Talimogene laherparepvec Approved, Experimental, Investigational Phase 2 1187560-31-1
3 Antineoplastic Agents, Immunological Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers Recruiting NCT02978625 Phase 2

Search NIH Clinical Center for Malignant Acrospiroma

Genetic Tests for Malignant Acrospiroma

Anatomical Context for Malignant Acrospiroma

MalaCards organs/tissues related to Malignant Acrospiroma:

42
Skin

Publications for Malignant Acrospiroma

Articles related to Malignant Acrospiroma:

(show all 24)
# Title Authors Year
1
Squamoid Eccrine Ductal Carcinoma: An Aggressive Mimicker of Squamous Cell Carcinoma. ( 29979196 )
2018
2
Squamoid eccrine ductal carcinoma. ( 29894529 )
2018
3
Dermoscopy of squamoid eccrine ductal carcinoma: an aid for early diagnosis. ( 30484539 )
2018
4
Malignant acrospiroma: a case report in the era of next generation sequencing. ( 28347286 )
2017
5
Squamoid eccrine ductal carcinoma of the scalp. ( 25752474 )
2016
6
Squamoid Eccrine Ductal Carcinoma: A Clinicopathologic Study of 30 Cases. ( 26796504 )
2016
7
Squamoid eccrine ductal carcinoma. ( 28099603 )
2016
8
Anatomoclinical study of 30 cases of sclerosing sweat duct carcinomas (microcystic adnexal carcinoma, syringomatous carcinoma and squamoid eccrine ductal carcinoma). ( 25873411 )
2015
9
PET/CT imaging of squamoid eccrine ductal carcinoma. ( 25243946 )
2015
10
Squamoid Eccrine Ductal Carcinoma. ( 26171108 )
2015
11
Malignant acrospiroma of chest and abdominal wall treated with chemotherapy. ( 23723491 )
2013
12
Mohs micrographic surgery in the setting of squamoid eccrine ductal carcinoma: addressing a diagnostic and therapeutic challenge. ( 23630640 )
2013
13
Surgical management of recurrent squamoid eccrine ductal carcinoma of the scalp. ( 22801148 )
2012
14
Squamoid eccrine ductal carcinoma of the scalp. ( 23110015 )
2012
15
Squamoid eccrine ductal carcinoma: inappropriate diagnosis. ( 22182240 )
2011
16
Squamoid eccrine ductal carcinoma: a case report and review of the literature. ( 20010402 )
2010
17
"Squamoid eccrine ductal carcinoma": an unusual low-grade case with follicular differentiation. Are these tumors squamoid variants of microcystic adnexal carcinoma? ( 19786851 )
2009
18
Mohs micrographic surgery for squamoid eccrine ductal carcinoma. ( 16416622 )
2005
19
Metastatic malignant acrospiroma of the hand. ( 11417993 )
2001
20
Recurrent malignant acrospiroma. Treatment by chest wall excision. ( 9723060 )
1998
21
Squamoid eccrine ductal carcinoma. ( 9639127 )
1998
22
Squamoid eccrine ductal carcinoma. ( 9088963 )
1997
23
Malignant acrospiroma. ( 2176667 )
1990
24
Sweat gland carcinoma of the hand (malignant acrospiroma). ( 2544641 )
1989

Variations for Malignant Acrospiroma

Expression for Malignant Acrospiroma

Search GEO for disease gene expression data for Malignant Acrospiroma.

Pathways for Malignant Acrospiroma

GO Terms for Malignant Acrospiroma

Sources for Malignant Acrospiroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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