Malignant Biphasic Mesothelioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Malignant Biphasic Mesothelioma

MalaCards integrated aliases for Malignant Biphasic Mesothelioma:

Name: Malignant Biphasic Mesothelioma ¹² ¹⁵

Mesothelioma, Biphasic, Malignant ¹² ⁷³

Mixed Mesothelioma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4486

NCIt ⁵⁰ C4282

SNOMED-CT ⁶⁸ 30383009

UMLS ⁷³ C0334515

Sources

Summaries for Malignant Biphasic Mesothelioma

MalaCards based summary : Malignant Biphasic Mesothelioma, also known as mesothelioma, biphasic, malignant, is related to malignant pleural mesothelioma and mesothelioma, malignant. An important gene associated with Malignant Biphasic Mesothelioma is WT1 (Wilms Tumor 1), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Cytoskeletal Signaling. The drugs Pembrolizumab and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and colon.

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Related Diseases for Malignant Biphasic Mesothelioma

Diseases related to Malignant Biphasic Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)

#	Related Disease	Score	Top Affiliating Genes
1	malignant pleural mesothelioma	30.0	CALB2 MSLN THBD WT1
2	mesothelioma, malignant	29.5	CALB2 CEACAM5 KRT7 MSLN THBD WT1
3	malignant epithelial mesothelioma	10.3	THBD WT1
4	fallopian tube carcinosarcoma	10.3	CALB2 WT1
5	sarcomatoid mesothelioma	10.2	THBD WT1
6	peritoneal benign neoplasm	10.2	CALB2 WT1
7	diffuse peritoneal leiomyomatosis	10.2	CALB2 WT1
8	venous hemangioma	10.2	CALB2 WT1
9	mixed germ cell-sex cord neoplasm	10.2	CALB2 WT1
10	spindle cell liposarcoma	10.2	CALB2 WT1
11	sertoli cell tumor	10.2	CALB2 WT1
12	peritoneal mesothelioma	10.2	THBD WT1
13	pneumatosis cystoides intestinalis	10.2	CALB2 WT1
14	endosalpingiosis	10.2	KRT7 WT1
15	breast squamous cell carcinoma	10.2	KRT10 KRT5
16	renal adenoma	10.2	KRT7 WT1
17	epithelial predominant wilms' tumor	10.2	KRT7 WT1
18	epidermolysis bullosa simplex with mottled pigmentation	10.2	KRT10 KRT5
19	dysgerminoma of ovary	10.2	CALB2 WT1
20	female reproductive endometrioid cancer	10.2	KRT7 WT1
21	metanephric adenoma	10.2	KRT7 WT1
22	lymphoepithelioma-like thymic carcinoma	10.2	EPCAM KRT5
23	cervix endometriosis	10.2	CALB2 CEACAM5
24	kidney benign neoplasm	10.2	KRT7 WT1
25	inverted transitional papilloma	10.1	KRT5 KRT7
26	balloon cell malignant melanoma	10.1	KRT5 KRT7
27	malignant leydig cell tumor	10.1	CALB2 KRT7
28	benign breast adenomyoepithelioma	10.1	KRT5 KRT7
29	epidermolysis bullosa simplex, dowling-meara type	10.1	KRT10 KRT5
30	malignant acrospiroma	10.1	CEACAM5 KRT5
31	adenosquamous carcinoma	10.1	KRT5 KRT7
32	esophageal adenosquamous carcinoma	10.1	CEACAM5 KRT5
33	ceruminoma	10.1	KRT5 KRT7
34	sensory organ benign neoplasm	10.1	KRT5 KRT7
35	middle ear adenoma	10.1	KRT5 KRT7
36	apocrine sweat gland neoplasm	10.1	KRT5 KRT7
37	prostatic acinar adenocarcinoma	10.1	KRT7 WT1
38	clear cell adenofibroma	10.1	CALB2 KRT7
39	mucinous bronchioloalveolar adenocarcinoma	10.1	CALB2 KRT7
40	bowen's disease	10.1	KRT10 KRT7
41	lymphoepithelioma-like carcinoma	10.1	KRT5 KRT7
42	lipoadenoma	10.1	KRT5 KRT7
43	nasal cavity squamous cell carcinoma	10.1	KRT5 KRT7
44	atypical choroid plexus papilloma	10.1	KRT5 KRT7
45	nephrogenic adenofibroma	10.1	KRT7 WT1
46	breast secretory carcinoma	10.1	KRT5 KRT7
47	horseshoe kidney	10.1	CALB2 KRT7
48	pregnancy adenoma	10.1	KRT5 KRT7
49	necrotizing sialometaplasia	10.1	KRT5 KRT7
50	mixed ductal-endocrine carcinoma	10.1	CALB2 CEACAM5

Graphical network of the top 20 diseases related to Malignant Biphasic Mesothelioma:

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Symptoms & Phenotypes for Malignant Biphasic Mesothelioma

Sources

Drugs & Therapeutics for Malignant Biphasic Mesothelioma

Drugs for Malignant Biphasic Mesothelioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Pembrolizumab

Approved

Phase 2

1374853-91-4

2

Antibodies

Phase 2,Phase 1

3

Immunoglobulins

Phase 2,Phase 1

4

Tin Fluorides

Phase 2

5

leucovorin

Approved

Phase 1

58-05-9

6006 143

Synonyms:

(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate

(6R,S)-5-Formyltetrahydrofolate

10-Formyl-7,8-dihydrofolate

10-Formyl-7,8-dihydrofolic acid

5 Formyltetrahydrofolate

5 Formyltetrahydropteroylglutamate

5-Formyl-5,6,7,8-tetrahydrofolate

5-Formyl-5,6,7,8-tetrahydrofolic acid

5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid

5-Formyltetrahydrofolate

5-formyltetrahydrofolic acid

5-Formyltetrahydrofolic acid

5-Formyltetrahydropteroylglutamate

5-Formyltetrahydropteroylglutamic acid

Acid, folinic

Acide folinique

Calcium citrovorum factor

Calcium folinate

Calcium leucovorin

Citrovorum factor

Factor, citrovorum

folinate

Folinate

Folinate, calcium

Folinic acid

Folinic acid calcium salt

Folinic acid calcium salt USP27

Folinic acid SF

Folinic acid-SF

L(-)-5-Formyl-5,6,7,8-tetrahydrofolate

L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid

Leucal

Leucovorin

Leucovorin calcium

Leucovorin folinic acid

Leucovorin, (D)-isomer

Leucovorin, (DL)-isomer

Leucovorin, (R)-isomer

Leucovorin, calcium

Leucovorin, calcium (1:1) salt

Leucovorin, calcium (1:1) salt, (DL)-isomer

Leucovorin, calcium (1:1) salt, pentahydrate

Leucovorin, monosodium salt

Leucovorinum

Leukovorin

Leukovorum

Levoleucovorin

L-leucovorin

L-Leucovorin

L-N-[P-[[(2-amino-5-Formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid

Monosodium salt leucovorin

N(5)-Formyltetrahydrofolate

N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid

N5-Formyl-5,6,7,8-tetrahydrofolate

N5-Formyl-5,6,7,8-tetrahydrofolic acid

N5-Formyltetrahydrofolate

N5-Formyltetrahydrofolic acid

Rescuvolin

Welcovorin

Wellcovorin

6

Pemetrexed

Approved, Investigational

Phase 1

150399-23-8, 137281-23-3

446556 60843

Synonyms:

(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

137281-23-3

150399-23-8

1juj

2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID

AC1L1U1D

AC1L2PDW

AC1L98DY

AC1L9JT6

AC1OCF51

AC1Q5R1W

Alimta

ALIMTA

Alimta (TN)

Bio-0078

C20H19N5O6.2Na

C20H21N5O6

CHEBI:195145

CHEBI:43746

CHEBI:474008

CHEMBL1200373

CHEMBL225072

CHEMBL59843

CID125891

CID394493

CID446556

CID60843

CID6918197

D03828

D07472

DB00642

disodium (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

disodium (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate

Disodium N-(p-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate

Disodium, pemetrexed

HSDB 7316

I06-1253

I06-1294

I06-2128

L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-, disodium salt

LS-172988

LS-173384

LY 231,514

LY 231514

LY-231,514

LY-2315

LY231514

LY-231514

LY231514 disodium

LYA

MTA

N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-D)Pyrimdin-5-yl)ethyl)benzoyl)glutamic acid

N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid

n-{4-[2-(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-d-glutamic acid

NCGC00167517-01

nchembio.108-comp6

NCI60_035021

NSC698037

Pemetrexed

Pemetrexed (INN)

Pemetrexed [INN:BAN]

Pemetrexed disodium

Pemetrexed Disodium

Pemetrexed disodium (USAN)

Pemetrexed disodium [USAN]

Rolazar

ST51053024

Tifolar

UNII-04Q9AIZ7NO

UNII-2PKU919BA9

7

Atezolizumab

Approved, Investigational

Phase 1

1380723-44-3

8

Cisplatin

Approved

Phase 1

15663-27-1

2767 441203 84093

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

9

Glutamic Acid

Approved, Nutraceutical

Phase 1

56-86-0

33032

Synonyms:

(2S)-2-Aminopentanedioate

(2S)-2-Aminopentanedioic acid

(S)-(+)-Glutamate

(S)-(+)-Glutamic acid

(S)-2-Aminopentanedioate

(S)-2-Aminopentanedioic acid

(S)-Glutamate

(S)-Glutamic acid

09581_FLUKA

10549-13-0

138-15-8 (unspecified hydrochloride)

138-16-9

16690-92-9 (di-hydrochloride salt)

19238-49-4 (unspecified calcium salt)

19473-49-5 (mono-potassium salt)

1-amino-Propane-1,3-dicarboxylate

1-Aminopropane-1,3-dicarboxylate

1-amino-Propane-1,3-dicarboxylic acid

1-Aminopropane-1,3-dicarboxylic acid

1ftj

1ii5

1xff

24595-14-0 (unspecified potassium salt)

24938-00-9

25513-46-6

26717-13-5

27322E29-9696-49C1-B541-86BEF72DE2F3

2-Aminoglutarate

2-Aminoglutaric acid

2-Aminopentanedioate

2-aminopentanedioic acid

2-Aminopentanedioic acid

49449_FLUKA

49449_SIGMA

55695-80-2 (mono-lithium salt)

56-86-0

6899-05-4

7558-63-6 (mono-ammonium salt)

84960-48-5

a-Aminoglutarate

a-Aminoglutaric acid

AB1002631

AC-11294

AC1L1OVN

AC1Q28OF

AC1Q4U8B

AC1Q4U8C

Acide glutamique

Acide glutamique [INN-French]

acido Glutamico

Acido glutamico

ácido glutámico

Acido glutamico [INN-Spanish]

Acidum glutamicum

Acidum glutamicum [INN-Latin]

Acidum glutaminicum

Aciglut

a-Glutamate

a-Glutamic acid

AI3-18472

alpha-Aminoglutarate

alpha-aminoglutaric acid

alpha-Aminoglutaric acid

alpha-Aminoglutaric acid (VAN)

alpha-Glutamate

alpha-Glutamic acid

alpha-L-Glutamic acid polymer

Aluminum L glutamate

Aluminum L-glutamate

AmbotzHAA1087

Aminoglutarate

Aminoglutaric acid

Biomol-NT_000170

BPBio1_001132

C00025

CCRIS 7314

CHEBI:16015

CHEMBL575060

CID33032

D Glutamate

D00007

DB00142

DB02517

D-Glutamate

D-Glutamiensuur

E

E 620

EINECS 200-293-7

EPA Pesticide Chemical Code 374350

FEMA No. 3285

FT-0085107

G0059

G1251_SIGMA

G5667_SIGMA

G8415_SIGMA

Glt

glu

Glu

Glusate

glut

Glut

glutacid

Glutacid

glutamate

Glutamate

Glutamate, potassium

GLUTAMIC ACID

Glutamic acid (H-3)

Glutamic Acid (L-glutamic acid)

Glutamic acid (VAN)

Glutamic Acid [USAN:INN]

Glutamic acid polymer

Glutamic acid, (D)-isomer

Glutamic acid, L- (7CI,8CI)

Glutamic acid, L-, peptides

Glutamicol

Glutamidex

Glutaminate

glutaminic acid

Glutaminic acid

Glutaminic acid (VAN)

Glutaminol

Glutaton

Gulutamine

Gulutamine (USP)

H-Glu-OH

HSCI1_000269

L Glutamate

L Glutamic acid

L-(+)-Glutamate

L-(+)-glutamic acid

L-(+)-Glutamic acid

L-2-Aminoglutaric acid

L-a-Aminoglutarate

L-a-Aminoglutaric acid

L-alpha-Aminoglutarate

L-alpha-Aminoglutaric acid

L-glu

L-Glu

L-glutamate

L-Glutamate

L-Glutamate, aluminum

L-glutamic acid

L-Glutamic acid

L-Glutamic acid (9CI)

L-Glutamic acid (JAN)

L-Glutamic acid hydrochloride

L-Glutamic acid, homopolymer

L-Glutamic acid, homopolymer (9CI)

L-Glutaminate

L-Glutaminic acid

L-Glutaminsaeure

Lopac0_000529

LS-2330

LS-71885

MolPort-001-770-254

NCGC00024502-01

NCGC00024502-02

NCGC00024502-03

NCGC00024502-04

nchembio.186-comp9

nchembio.198-comp6

nchembio.2007.55-comp22

nchembio.266-comp23

nchembio.586-comp22

nchembio816-comp2

NSC 143503

PDSP1_000128

PDSP1_001539

PDSP2_000127

PDSP2_001523

Poly(alpha-L-glutamic acid)

POLYGLUTAMIC ACID

Poly-L-glutamate

Potassium glutamate

Sodium Glutamate (L-glutamic Acid)

Tocris-0218

UNII-3KX376GY7L

W328502_ALDRICH

10

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 1

59-30-3

6037

Synonyms:

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

01769_FLUKA

2d0k

33609-88-0

36653-55-1 (mono-potassium salt)

59-30-3

6484-89-5 (mono-hydrochloride salt)

AC-11682

AC1L1LNX

Acfol (Spain)

Acide folique

Acide folique [INN-French]

Acido folico

Acido folico [INN-Spanish]

Acidum folicum

Acidum folicum [INN-Latin]

Acifolic

AI3-26387

AKOS000503224

Antianemia factor

Apo-Folic

ARONIS014410

b9, Vitamin

BIDD:ER0563

BIDD:GT0641

BIF0608

bmse000299

BPBio1_000654

BSPBio_000594

BSPBio_002338

C00504

C20H20N6O6

CAS-59-30-3

CCRIS 666

CHEBI:27470

CHEMBL1622

CID6037

CPD000471860

Cytofol

D00070

DB00158

DivK1c_000494

Dosfolat b activ

Dosfolat B activ

EINECS 200-419-0

F0043

F7876_SIAL

F7876_SIGMA

F8758_SIGMA

F8798_SIAL

F8890_SIGMA

Facid

Factor U

FOL

Folacid

Folacin

Folaemin

Folaemin [Netherlands]

Folan

Folasic (Australia)

Folate

Folbal

Folcidin

Folcidin (VAN)

Folcysteine

Foldine

Foldine [France]

Folettes

Foliamin

Folic

folic acid

Folic acid (JP15/USP/INN)

Folic acid (TN)

Folic acid [BAN:INN:JAN]

Folic acid [INN:BAN:JAN]

Folic acid dihydrate

Folic acid, (D)-isomer

Folic acid, (DL)-isomer

Folic acid, calcium salt (1:1)

Folic acid, monopotassium salt

Folic acid, monosodium salt

Folic acid, potassium salt

Folic acid, sodium salt

Folicet

Folicet (TN)

Folico

Folico (Italy)

Folina

Folina (Italy)

Folipac

Folsaeure

Folsan

Folsaure

Folsäure

Folsav

Folvite

Folvron

Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L

HMS1921D20

HMS2092N17

HMS501I16

HSDB 2002

IDI1_000494

Incafolic

InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s

KBio1_000494

KBio2_001861

KBio2_004429

KBio2_006997

KBio3_001558

KBioGR_002222

KBioSS_001861

Kyselina listova

Kyselina listova [Czech]

Liver lactobacillus casei factor

Liver Lactobacillus casei factor

LS-2157

Millafol

Mission prenatal

Mittafol

MLS001304016

MLS001335861

MolPort-004-285-551

N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid

N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-Pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

NCGC00016265-01

NCGC00142391-01

nchembio.108-comp10

Nifolin

Nifolin [Denmark]

NINDS_000494

Novofolacid

Novofolacid [Canada]

N-Pteroyl-L-glutamate

N-pteroyl-L-glutamic acid

N-Pteroyl-L-glutamic acid

NSC 3073

PGA

PGA (VAN)

Prestwick_230

Prestwick3_000627

PteGlu

Pteroylglutamate

Pteroylglutamic acid

Pteroyl-L-glutamate

Pteroyl-L-glutamic acid

Pteroyl-L-monoglutamate

Pteroyl-L-monoglutamic acid

Pteroylmonoglutamate

Pteroylmonoglutamic acid

SAM002264616

SDCCGMLS-0066738.P001

Serum Folate Level

SMP2_000137

SMR000471860

SPBio_001357

Spectrum_001381

SPECTRUM1502020

Spectrum2_001459

Spectrum3_000749

Spectrum4_001751

Spectrum5_000602

UNII-935E97BOY8

Usaf cb-13

Vitamin B11

Vitamin b9

Vitamin B9

Vitamin Bc

Vitamin BC

Vitamin be

Vitamin Be

Vitamin m

Vitamin M

11

Immunologic Factors

Phase 1

12

Vitamin B9

Phase 1

13

Vitamin B Complex

Phase 1

14

Nucleic Acid Synthesis Inhibitors

Phase 1

15

Folic Acid Antagonists

Phase 1

16

Antibodies, Monoclonal

Phase 1

17

Folate

Phase 1

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Pembrolizumab in Treating Patients With Malignant Mesothelioma	Active, not recruiting	NCT02399371	Phase 2
2	Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma	Recruiting	NCT03228537	Phase 1	Atezolizumab;Cisplatin;Pemetrexed Disodium

Search NIH Clinical Center for Malignant Biphasic Mesothelioma

Sources

Genetic Tests for Malignant Biphasic Mesothelioma

Sources

Anatomical Context for Malignant Biphasic Mesothelioma

MalaCards organs/tissues related to Malignant Biphasic Mesothelioma:

⁴¹

Liver, Kidney, Colon, Ovary, Prostate, Testis, Thymus

Sources

Publications for Malignant Biphasic Mesothelioma

Articles related to Malignant Biphasic Mesothelioma:

#	Title	Authors	Year
1	Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis. ( 19195066 )	Sasaki M....Nakanuma Y.	2009
2	Case of malignant biphasic mesothelioma in a dog. ( 11765328 )		2001

Sources

Genes for Malignant Biphasic Mesothelioma

Genes related to Malignant Biphasic Mesothelioma (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	WT1	Wilms Tumor 1	Protein Coding	21.44	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	THBD	Thrombomodulin	Protein Coding	20.86	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	KRT5	Keratin 5	Protein Coding	14.99	DISEASES inferred ¹⁵
4	KRT10	Keratin 10	Protein Coding	14.74	DISEASES inferred ¹⁵
5	EPCAM	Epithelial Cell Adhesion Molecule	Protein Coding	13.82	DISEASES inferred ¹⁵
6	KRT7	Keratin 7	Protein Coding	13.63	DISEASES inferred ¹⁵
7	MSLN	Mesothelin	Protein Coding	11.43	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	CALB2	Calbindin 2	Protein Coding	11.15	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	OSCAR	Osteoclast Associated, Immunoglobulin-Like Receptor	Protein Coding	5.57	DISEASES inferred ¹⁵
10	FUT4	Fucosyltransferase 4	Protein Coding	4.04	DISEASES inferred ¹⁵
11	CEACAM5	Carcinoembryonic Antigen Related Cell Adhesion Molecule 5	Protein Coding	2.98	DISEASES inferred ¹⁵

Sources

Variations for Malignant Biphasic Mesothelioma

Sources

Expression for Malignant Biphasic Mesothelioma

Search GEO for disease gene expression data for Malignant Biphasic Mesothelioma.

Sources

Pathways for Malignant Biphasic Mesothelioma

Pathways related to Malignant Biphasic Mesothelioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cell surface interactions at the vascular wall ⁶⁶ Show member pathways Fibronectin matrix formation ⁶⁶ PECAM1 interactions ⁶⁶ Tie2 Signaling ⁶⁶	11.58	CEACAM5 EPCAM THBD
2	Cytoskeletal Signaling ⁴	11.41	EPCAM KRT10 KRT5 KRT7
3	Adhesion ⁴	11.22	CEACAM5 EPCAM MSLN

Sources

GO Terms for Malignant Biphasic Mesothelioma

Cellular components related to Malignant Biphasic Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular exosome	GO:0070062	9.63	CEACAM5 EPCAM KRT10 KRT5 KRT7 OSCAR
2	intermediate filament	GO:0005882	9.13	KRT10 KRT5 KRT7
3	cell surface	GO:0009986	9.1	CEACAM5 EPCAM FUT4 MSLN OSCAR THBD

Biological processes related to Malignant Biphasic Mesothelioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	ureteric bud development	GO:0001657	9.16	EPCAM WT1
2	keratinization	GO:0031424	9.13	KRT10 KRT5 KRT7
3	cornification	GO:0070268	8.8	KRT10 KRT5 KRT7

Sources

Sources for Malignant Biphasic Mesothelioma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia