MCID: MLG039
MIFTS: 22

Malignant Essential Hypertension

Categories: Blood diseases, Cancer diseases, Cardiovascular diseases, Genetic diseases, Nephrological diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Malignant Essential Hypertension

MalaCards integrated aliases for Malignant Essential Hypertension:

Name: Malignant Essential Hypertension 12 15 70
Accelerated Essential Hypertension 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10823
ICD9CM 34 401.0
NCIt 50 C34802
SNOMED-CT 67 78975002
UMLS 70 C0024588

Summaries for Malignant Essential Hypertension

MalaCards based summary : Malignant Essential Hypertension, also known as accelerated essential hypertension, is related to hypertension, essential and malignant hypertension. An important gene associated with Malignant Essential Hypertension is KLKB1 (Kallikrein B1). Affiliated tissues include eye.

Related Diseases for Malignant Essential Hypertension

Diseases in the Familial Hypertension family:

Hypertension, Essential Hypertension, Essential 1
Hypertension, Essential 2 Hypertension, Essential 3
Hypertension, Essential 4 Hypertension, Essential 5
Hypertension, Essential 6 Hypertension, Essential 7
Hypertension, Essential 8 Malignant Essential Hypertension
Malignant Hypertension Benign Essential Hypertension
Benign Secondary Hypertension Malignant Secondary Hypertension
Hypertension Due to Gain-of-Function Mutations in the Mineralocorticoid Receptor

Diseases related to Malignant Essential Hypertension via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hypertension, essential 10.5
2 malignant hypertension 10.2
3 hyperaldosteronism, familial, type iv 9.9
4 renal hypertension 9.9
5 benign essential hypertension 9.9
6 arteriosclerosis 9.9
7 glomerulonephritis 9.9
8 kidney disease 9.9

Comorbidity relations with Malignant Essential Hypertension via Phenotypic Disease Network (PDN): (show all 36)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Anxiety
Aortic Valve Disease 1 Basilar Artery Insufficiency
Benign Essential Hypertension Bronchitis
Cerebral Atherosclerosis Cerebrovascular Disease
Chronic Kidney Disease Deficiency Anemia
Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Hypertensive Encephalopathy
Hypertensive Retinopathy Hypothyroidism
Intermediate Coronary Syndrome Intracranial Thrombosis
Iron Deficiency Anemia Kidney Disease
Malignant Renovascular Hypertension Mitral Valve Disease
Peripheral Vascular Disease Renal Artery Atheroma
Respiratory Failure Schizophreniform Disorder
Sinoatrial Node Disease Swallowing Disorders
Transient Cerebral Ischemia Vertebral Artery Insufficiency

Graphical network of the top 20 diseases related to Malignant Essential Hypertension:



Diseases related to Malignant Essential Hypertension

Symptoms & Phenotypes for Malignant Essential Hypertension

Drugs & Therapeutics for Malignant Essential Hypertension

Search Clinical Trials , NIH Clinical Center for Malignant Essential Hypertension

Genetic Tests for Malignant Essential Hypertension

Anatomical Context for Malignant Essential Hypertension

MalaCards organs/tissues related to Malignant Essential Hypertension:

40
Eye

Publications for Malignant Essential Hypertension

Articles related to Malignant Essential Hypertension:

(show all 31)
# Title Authors PMID Year
1
Bilateral papillophlebitis in a patient with accelerated essential hypertension. 61
18025657 2007
2
Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension. 61
10930193 2000
3
Renal function in treated and untreated hypertension. 61
9783487 1998
4
Human leukocyte antigens and malignant essential hypertension. 61
9657633 1998
5
Does non-malignant essential hypertension cause renal damage? A clinician's view. 61
9004097 1996
6
Functional autoimmune epitope on alpha 1-adrenergic receptors in patients with malignant hypertension. 61
7527885 1994
7
Autoantibodies against cardiac G-protein-coupled receptors define different populations with cardiomyopathies but not with hypertension. 61
8020188 1994
8
Clinical features of end-stage renal failure in patients with essential hypertension. 61
8022111 1994
9
Elevated sympathetic nerve activity in patients with accelerated essential hypertension. 61
8325991 1993
10
Regression of left ventricular hypertrophy in previously untreated essential hypertension: different effects of enalapril and hydrochlorothiazide. 61
1338083 1992
11
[Japanese clinical statistical data of patients with malignant essential hypertension]. 61
1344353 1992
12
Urinary kallikrein excretion is low in malignant essential hypertension. 61
1325521 1992
13
Structural cardiovascular changes in essential hypertension. Studies on the effect of antihypertensive therapy. 61
1345261 1992
14
[Echocardiographic features of left ventricular hypertrophy and contractility in malignant hypertension]. 61
2530333 1989
15
[Predisposing factors for the development of malignant essential hypertension]. 61
3509169 1987
16
Predisposing factors for the development of malignant essential hypertension. 61
3662703 1987
17
[The comparison of histories of hypertension and renal function between group III and group IV (Keith-Wagener criteria) malignant essential hypertension]. 61
3441058 1987
18
Renal haemodynamics and comparative effects of captopril in patients with benign- or malignant-essential hypertension, or with chronic renal failure. 61
3301082 1987
19
Prospective measurement of glomerular filtration rate and effective renal plasma flow during treatment of malignant essential hypertension. 61
6494086 1984
20
Plasma vasopressin and blood pressure. Studies in normal subjects and in benign essential hypertension at rest and after postural challenge. 61
6849715 1983
21
Renal function as an indicator of prognosis in malignant essential hypertension. 61
7089493 1982
22
Immunological changes in patients with previous malignant essential hypertension. 61
6110039 1981
23
[Effect of neo-synephrine eye drops on the blood pressure of a young hypertensive patient (author's transl)]. 61
7442063 1980
24
[The effects of Sar 1-Ile 8-Angiotensin II in malignant essential hypertension]. 61
400447 1979
25
An ultrastructural analysis of renal arterioles in benign and malignant essential hypertensions. 61
851350 1977
26
Vascular lesions of malignant essential hypertension. 61
5567174 1971
27
Vascular lesions of malignant essential hypertension. 61
5567956 1971
28
[Sympatho-adrenalectomy in malignant essential hypertension]. 61
5539953 1971
29
Vascular lesions of malignant essential hypertension. 61
5504381 1970
30
Successful twin pregnancy after treatment of malignant essential hypertension. 61
13572832 1958
31
Clinicopathologic conference; generalized arteriosclerosis; malignant essential hypertension with dissecting aneurysm of the artery and coronary occlusion. 61
15426209 1950

Variations for Malignant Essential Hypertension

Expression for Malignant Essential Hypertension

Search GEO for disease gene expression data for Malignant Essential Hypertension.

Pathways for Malignant Essential Hypertension

GO Terms for Malignant Essential Hypertension

Sources for Malignant Essential Hypertension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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