MCID: MLG066
MIFTS: 21

Malignant Gastric Germ Cell Tumor

Categories: Cancer diseases, Gastrointestinal diseases
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Aliases & Classifications for Malignant Gastric Germ Cell Tumor

MalaCards integrated aliases for Malignant Gastric Germ Cell Tumor:

Name: Malignant Gastric Germ Cell Tumor 11 14 71
Malignant Gastric Germ Cell Tumour 11
Germ Cell Tumour of the Stomach 11
Germ Cell Tumor of the Stomach 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4716
NCIt 49 C6448
UMLS 71 C1333769 C1334584

Summaries for Malignant Gastric Germ Cell Tumor

MalaCards based summary: Malignant Gastric Germ Cell Tumor, also known as malignant gastric germ cell tumour, is related to fetal and neonatal alloimmune thrombocytopenia and esophagus lymphoma. An important gene associated with Malignant Gastric Germ Cell Tumor is SNORA16A (Small Nucleolar RNA, H/ACA Box 16A), and among its related pathways/superpathways are Actin Nucleation by ARP-WASP Complex and MAPK Signaling: Mitogens.

Related Diseases for Malignant Gastric Germ Cell Tumor

Diseases related to Malignant Gastric Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 fetal and neonatal alloimmune thrombocytopenia 10.1 ITGB3 ITGA2B
2 esophagus lymphoma 10.1 ALK AFP
3 bleeding disorder, platelet-type, 16 10.1 ITGB3 ITGA2B
4 autosomal dominant macrothrombocytopenia 10.1 ITGB3 ITGA2B
5 liver leiomyoma 10.1 ALK AFP
6 heparin-induced thrombocytopenia 10.1 ITGB3 ITGA2B
7 acquired thrombocytopenia 10.1 ITGB3 ITGA2B
8 bleeding disorder, platelet-type, 18 10.1 ITGB3 ITGA2B
9 thrombasthenia 10.0 ITGB3 ITGA2B
10 primary thrombocytopenia 10.0 ITGB3 ITGA2B
11 coronary thrombosis 10.0 ITGB3 ITGA2B
12 thrombocytopenia due to platelet alloimmunization 10.0 ITGB3 ITGA2B
13 fallopian tube clear cell adenocarcinoma 10.0 NTRK1 ITGB3
14 collecting duct carcinoma 10.0 CA9 ALK
15 acute erythroid leukemia 10.0 ITGA2B GYPA
16 malignant giant cell tumor of the tendon sheath 9.9 NTRK1 ALK
17 spitzoid melanoma 9.9 NTRK1 ALK
18 childhood fibrosarcoma 9.9 NTRK1 ALK
19 autonomic nervous system benign neoplasm 9.9 NTRK1 ALK
20 testicular torsion 9.9 MPO AFP
21 peripheral nervous system benign neoplasm 9.9 NTRK1 ALK
22 myelitis 9.9 ITGB3 ITGA2B
23 myeloproliferative syndrome, transient 9.9 ITGB3 ITGA2B GYPA
24 infantile myofibromatosis 9.9 NTRK1 ALK
25 congenital fibrosarcoma 9.9 NTRK1 ALK
26 differentiated thyroid carcinoma 9.9 NTRK1 ALK
27 appendix lymphoma 9.9 MPO ITGB3
28 thrombocytopenic purpura, autoimmune 9.9 ITGB3 ITGA2B
29 cecal disease 9.9 MPO AFP
30 congenital mesoblastic nephroma 9.9 NTRK1 ALK
31 ganglioneuroblastoma 9.8 NTRK1 ALK
32 infective endocarditis 9.8 MPO ITGA2B
33 mesenchymal cell neoplasm 9.8 NTRK1 ALK
34 autoimmune disease of blood 9.8 MPO ITGA2B
35 pericardium disease 9.8 MPO ALK
36 beta-thalassemia major 9.7 ITGA2B GYPA
37 blood coagulation disease 9.7 MPO ITGB3 ITGA2B
38 acute megakaryocytic leukemia 9.7 MPO ITGB3 ITGA2B
39 blood platelet disease 9.7 MPO ITGB3 ITGA2B
40 fibrosarcoma 9.7 NTRK1 CA9 ALK
41 exanthem 9.6 MPO ALK
42 leukemia, chronic myeloid 9.3 NTRK1 MPO ITGB3 ALK
43 malignant gastric teratoma 9.2 SNORA16A NTRK1 CA9 CA14 ALK AFP
44 leukemia, acute myeloid 8.9 NTRK1 MPO ITGB3 ITGA2B GYPA ALK
45 gastric teratoma 8.7 SNORA16A MPO ITGB3 ITGA2B GYPA CA9

Graphical network of the top 20 diseases related to Malignant Gastric Germ Cell Tumor:



Diseases related to Malignant Gastric Germ Cell Tumor

Symptoms & Phenotypes for Malignant Gastric Germ Cell Tumor

Drugs & Therapeutics for Malignant Gastric Germ Cell Tumor

Search Clinical Trials, NIH Clinical Center for Malignant Gastric Germ Cell Tumor

Genetic Tests for Malignant Gastric Germ Cell Tumor

Anatomical Context for Malignant Gastric Germ Cell Tumor

Publications for Malignant Gastric Germ Cell Tumor

Articles related to Malignant Gastric Germ Cell Tumor:

# Title Authors PMID Year
1
Gastric immature teratoma arising from the lesser curvature of the stomach: A rare case report. 62
35381809 2022
2
Immature gastric teratoma in an infant: a case report and review of the literatures. 62
27761247 2016

Variations for Malignant Gastric Germ Cell Tumor

Expression for Malignant Gastric Germ Cell Tumor

Search GEO for disease gene expression data for Malignant Gastric Germ Cell Tumor.

Pathways for Malignant Gastric Germ Cell Tumor

GO Terms for Malignant Gastric Germ Cell Tumor

Cellular components related to Malignant Gastric Germ Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microvillus membrane GO:0031528 9.46 ITGB3 CA9
2 integrin complex GO:0008305 9.26 ITGB3 ITGA2B
3 platelet alpha granule membrane GO:0031092 8.92 ITGB3 ITGA2B

Biological processes related to Malignant Gastric Germ Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine autophosphorylation GO:0038083 8.92 NTRK1 ALK

Molecular functions related to Malignant Gastric Germ Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydro-lyase activity GO:0016836 9.26 CA9 CA14
2 carbonate dehydratase activity GO:0004089 8.92 CA9 CA14

Sources for Malignant Gastric Germ Cell Tumor

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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