MCID: MLG018
MIFTS: 24

Malignant Giant Cell Tumor of Soft Parts

Categories: Cancer diseases

Aliases & Classifications for Malignant Giant Cell Tumor of Soft Parts

MalaCards integrated aliases for Malignant Giant Cell Tumor of Soft Parts:

Name: Malignant Giant Cell Tumor of Soft Parts 12 15
Malignant Giant Cell Neoplasm of Soft Parts 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5638
NCIt 50 C8380
SNOMED-CT 68 48460009
UMLS 73 C0334554

Summaries for Malignant Giant Cell Tumor of Soft Parts

MalaCards based summary : Malignant Giant Cell Tumor of Soft Parts, also known as malignant giant cell neoplasm of soft parts, is related to giant cell tumor and malignant giant cell tumor. An important gene associated with Malignant Giant Cell Tumor of Soft Parts is ACTC1 (Actin, Alpha, Cardiac Muscle 1), and among its related pathways/superpathways are Lysosome and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include skin, prostate and brain.

Related Diseases for Malignant Giant Cell Tumor of Soft Parts

Diseases related to Malignant Giant Cell Tumor of Soft Parts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 giant cell tumor 30.8 ACTC1 PTPRC
2 malignant giant cell tumor 30.7 ACP5 ACTC1 S100B
3 dermatofibrosarcoma protuberans 30.1 ACTC1 S100B
4 myopericytoma 10.1 ACTC1 S100B
5 ossifying fibromyxoid tumor 10.1 ACTC1 S100B
6 spiradenoma 10.1 ACTC1 S100B
7 angiocentric glioma 10.1 ACTC1 S100B
8 cutaneous fibrous histiocytoma 10.1 ACTC1 S100B
9 fibrous histiocytoma 10.1 ACTC1 S100B
10 spindle cell sarcoma 10.1 ACTC1 S100B
11 light chain deposition disease 10.1 ACTC1 CD68
12 ischemic fasciitis 10.1 ACTC1 CD68
13 polymorphous low-grade adenocarcinoma 10.1 ACTC1 S100B
14 hemangiopericytoma, malignant 10.1 ACTC1 S100B
15 papillary ependymoma 10.1 CD68 S100B
16 non-langerhans-cell histiocytosis 10.1 ACTC1 LYZ
17 granular cell tumor 10.1 CD68 S100B
18 meningeal melanocytoma 10.0 CD68 S100B
19 inflammatory myofibroblastic tumor 10.0 ACTC1 S100B
20 juvenile xanthogranuloma 10.0 LYZ S100B
21 central nervous system sarcoma 10.0 CD68 LYZ
22 pleomorphic adenoma 10.0 ACTC1 S100B
23 cardiomyopathy, infantile histiocytoid 10.0 CD68 LYZ
24 adult xanthogranuloma 10.0 CD68 LYZ
25 liver sarcoma 10.0 CD68 LYZ
26 granulomatous myositis 10.0 CD68 LYZ
27 leiomyosarcoma 10.0 ACTC1 S100B
28 acute salpingitis 10.0 CD68 LYZ
29 aleukemic leukemia cutis 10.0 CD68 LYZ
30 malignant peripheral nerve sheath tumor 10.0 ACTC1 S100B
31 ulcerative stomatitis 10.0 CD68 LYZ
32 xanthogranulomatous pyelonephritis 10.0 CD68 LYZ
33 congenital epulis 10.0 CD68 LYZ
34 reticulum cell sarcoma 10.0 ACTC1 PTPRC
35 histiocytosis 10.0 PTPRC S100B
36 xanthogranulomatous cholecystitis 10.0 CD68 LYZ
37 gliosarcoma 10.0 ACTC1 S100B
38 nodular tenosynovitis 10.0 CD68 PTPRC
39 extracutaneous mastocytoma 10.0 CD68 PTPRC
40 brain sarcoma 10.0 CD68 PTPRC
41 glomeruloid hemangioma 10.0 CD68 PTPRC
42 conventional fibrosarcoma 10.0 CD68 PTPRC
43 hodgkin's lymphoma, lymphocytic depletion 10.0 CD68 PTPRC
44 lymphatic system disease 9.9 CD68 LYZ
45 photokeratitis 9.9 CD68 PTPRC
46 pigmented villonodular synovitis 9.9 ACP5 PTPRC
47 olfactory neuroblastoma 9.9 PTPRC S100B
48 rhabdoid tumor predisposition syndrome 1 9.9 ACTC1 PTPRC
49 histiocytic and dendritic cell cancer 9.9 LYZ PTPRC
50 melkersson-rosenthal syndrome 9.9 CD68 PTPRC

Graphical network of the top 20 diseases related to Malignant Giant Cell Tumor of Soft Parts:



Diseases related to Malignant Giant Cell Tumor of Soft Parts

Symptoms & Phenotypes for Malignant Giant Cell Tumor of Soft Parts

Drugs & Therapeutics for Malignant Giant Cell Tumor of Soft Parts

Search Clinical Trials , NIH Clinical Center for Malignant Giant Cell Tumor of Soft Parts

Genetic Tests for Malignant Giant Cell Tumor of Soft Parts

Anatomical Context for Malignant Giant Cell Tumor of Soft Parts

MalaCards organs/tissues related to Malignant Giant Cell Tumor of Soft Parts:

41
Skin, Prostate, Brain, Liver

Publications for Malignant Giant Cell Tumor of Soft Parts

Articles related to Malignant Giant Cell Tumor of Soft Parts:

# Title Authors Year
1
Malignant giant cell tumor of soft parts. ( 14997349 )
2004
2
Malignant giant cell tumor of soft parts in a mare. ( 14524631 )
2003
3
Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. ( 10496598 )
1999
4
Metastatic dermatofibrosarcoma protuberans with fibrosarcomatous change in the absence of local recurrence. A case report of simultaneous occurrence with a malignant giant cell tumor of soft parts. ( 8319177 )
1993
5
Malignant giant cell tumor of soft parts presenting as a skin tumor. ( 2658646 )
1989
6
Sarcomatoid carcinoma (so-called pseudosarcoma) of the larynx simulating malignant giant cell tumor of soft parts. A case report. ( 6465100 )
1984
7
The importance of recognizing malignant giant cell tumor of soft parts. ( 277073 )
1978
8
Malignant giant cell tumor of soft parts. An ultrastructural study of four cases. ( 195704 )
1977
9
Primary prostatic malignant giant cell tumor of soft parts. ( 1067447 )
1976
10
Malignant giant cell tumor of soft parts. An analysis of 32 cases. ( 5031245 )
1972

Variations for Malignant Giant Cell Tumor of Soft Parts

Expression for Malignant Giant Cell Tumor of Soft Parts

Search GEO for disease gene expression data for Malignant Giant Cell Tumor of Soft Parts.

Pathways for Malignant Giant Cell Tumor of Soft Parts

Pathways related to Malignant Giant Cell Tumor of Soft Parts according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 ACP5 CD68
2 10.69 CD68 PTPRC

GO Terms for Malignant Giant Cell Tumor of Soft Parts

Biological processes related to Malignant Giant Cell Tumor of Soft Parts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 8.96 ACP5 LYZ
2 neutrophil degranulation GO:0043312 8.8 CD68 LYZ PTPRC

Sources for Malignant Giant Cell Tumor of Soft Parts

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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