MCID: MLG051
MIFTS: 23

Malignant Glandular Tumor of Peripheral Nerve Sheath

Categories: Cancer diseases, Neuronal diseases, Endocrine diseases

Aliases & Classifications for Malignant Glandular Tumor of Peripheral Nerve Sheath

MalaCards integrated aliases for Malignant Glandular Tumor of Peripheral Nerve Sheath:

Name: Malignant Glandular Tumor of Peripheral Nerve Sheath 12 15
Glandular Malignant Peripheral Nerve Sheath Tumor 73
Glandular Mpnst 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8420
NCIt 50 C6560
SNOMED-CT 68 699658004 699659007
UMLS 73 C1333821

Summaries for Malignant Glandular Tumor of Peripheral Nerve Sheath

MalaCards based summary : Malignant Glandular Tumor of Peripheral Nerve Sheath, also known as glandular malignant peripheral nerve sheath tumor, is related to plexiform schwannoma and duodenal somatostatinoma. An important gene associated with Malignant Glandular Tumor of Peripheral Nerve Sheath is B3GAT1 (Beta-1,3-Glucuronyltransferase 1), and among its related pathways/superpathways are Neuroscience and MECP2 and Associated Rett Syndrome. Related phenotypes are behavior/neurological and nervous system

Related Diseases for Malignant Glandular Tumor of Peripheral Nerve Sheath

Diseases related to Malignant Glandular Tumor of Peripheral Nerve Sheath via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 plexiform schwannoma 10.2 B3GAT1 NF1
2 duodenal somatostatinoma 10.2 NF1 SST
3 nephrogenic adenofibroma 10.1 B3GAT1 NF1
4 hodgkin's lymphoma, mixed cellularity 10.1 B3GAT1 UCHL1
5 phaeochromocytoma 10.0 NF1 SST
6 atypical neurofibroma 10.0 NF1 UCHL1
7 adenoma of the pancreas 9.8 SST SYP
8 pancreatic somatostatinoma 9.8 SST SYP
9 gastrointestinal neuroendocrine tumor 9.8 SST SYP
10 obstructive hydrocephalus 9.8 NF1 SYP
11 pancreatoblastoma 9.8 SST SYP
12 carcinoid tumors, intestinal 9.8 SST SYP
13 ampulla of vater neoplasm 9.8 SST SYP
14 binswanger's disease 9.8 SST SYP
15 carcinoid syndrome 9.8 SST SYP
16 functional colonic disease 9.8 SST SYP
17 optic nerve neoplasm 9.7 NF1 SYP
18 ectopic cushing syndrome 9.7 SST SYP
19 mixed ductal-endocrine carcinoma 9.7 SST SYP
20 colonic pseudo-obstruction 9.7 SST SYP
21 cauda equina neoplasm 9.7 SYP UCHL1
22 optic nerve glioma 9.7 NF1 SYP
23 intestinal pseudo-obstruction 9.7 SST SYP
24 neurofibroma 9.6 NF1 SYP
25 pineal parenchymal tumor of intermediate differentiation 9.6 SYP UCHL1
26 peripheral nervous system neoplasm 9.6 NF1 SYP
27 cell type benign neoplasm 9.6 SST SYP
28 merkel cell carcinoma 9.6 SST SYP
29 nervous system cancer 9.6 NF1 SYP
30 endocrine gland cancer 9.5 SST SYP
31 multiple endocrine neoplasia, type i 9.5 SST SYP
32 pilocytic astrocytoma 9.4 NF1 SYP
33 tuberous sclerosis 9.3 NF1 SYP
34 organ system benign neoplasm 9.2 NF1 SST SYP
35 paraganglioma 9.2 NF1 SST SYP
36 neuroendocrine tumor 9.2 SST SYP
37 meningioma, familial 9.2 NF1 SST SYP
38 pheochromocytoma 9.2 NF1 SST SYP
39 gastric small cell carcinoma 9.2 B3GAT1 SYP UCHL1
40 gastrointestinal stromal tumor 9.1 NF1 SYP UCHL1
41 small cell cancer of the lung 9.0 SST SYP

Graphical network of the top 20 diseases related to Malignant Glandular Tumor of Peripheral Nerve Sheath:



Diseases related to Malignant Glandular Tumor of Peripheral Nerve Sheath

Symptoms & Phenotypes for Malignant Glandular Tumor of Peripheral Nerve Sheath

MGI Mouse Phenotypes related to Malignant Glandular Tumor of Peripheral Nerve Sheath:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.35 B3GAT1 NF1 SST SYP UCHL1
2 nervous system MP:0003631 9.02 B3GAT1 NF1 SST SYP UCHL1

Drugs & Therapeutics for Malignant Glandular Tumor of Peripheral Nerve Sheath

Search Clinical Trials , NIH Clinical Center for Malignant Glandular Tumor of Peripheral Nerve Sheath

Genetic Tests for Malignant Glandular Tumor of Peripheral Nerve Sheath

Anatomical Context for Malignant Glandular Tumor of Peripheral Nerve Sheath

Publications for Malignant Glandular Tumor of Peripheral Nerve Sheath

Articles related to Malignant Glandular Tumor of Peripheral Nerve Sheath:

# Title Authors Year
1
Radiation-Induced Glandular Malignant Peripheral Nerve Sheath Tumor. ( 28530162 )
2017
2
Glandular malignant peripheral nerve sheath tumor: an unusual case showing histologically malignant glands. ( 10975940 )
2000

Variations for Malignant Glandular Tumor of Peripheral Nerve Sheath

Expression for Malignant Glandular Tumor of Peripheral Nerve Sheath

Search GEO for disease gene expression data for Malignant Glandular Tumor of Peripheral Nerve Sheath.

Pathways for Malignant Glandular Tumor of Peripheral Nerve Sheath

Pathways related to Malignant Glandular Tumor of Peripheral Nerve Sheath according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 NF1 SYP UCHL1
2 10.75 NF1 SST

GO Terms for Malignant Glandular Tumor of Peripheral Nerve Sheath

Cellular components related to Malignant Glandular Tumor of Peripheral Nerve Sheath according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection terminus GO:0044306 8.62 SYP UCHL1

Biological processes related to Malignant Glandular Tumor of Peripheral Nerve Sheath according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of MAP kinase activity GO:0043407 8.96 NF1 UCHL1
2 regulation of long-term neuronal synaptic plasticity GO:0048169 8.62 NF1 SYP

Sources for Malignant Glandular Tumor of Peripheral Nerve Sheath

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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