MCID: MLG070
MIFTS: 19

Malignant Iris Melanoma

Categories: Eye diseases, Neuronal diseases, Cancer diseases, Skin diseases

Aliases & Classifications for Malignant Iris Melanoma

MalaCards integrated aliases for Malignant Iris Melanoma:

Name: Malignant Iris Melanoma 12 15
Malignant Melanoma of Iris 12
Melanoma of the Iris 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6994
NCIt 50 C9088
SNOMED-CT 68 255012009
UMLS 73 C0346373

Summaries for Malignant Iris Melanoma

MalaCards based summary : Malignant Iris Melanoma, also known as malignant melanoma of iris, is related to melanoma, uveal and iris spindle cell melanoma. An important gene associated with Malignant Iris Melanoma is S100B (S100 Calcium Binding Protein B), and among its related pathways/superpathways is Ca, cAMP and Lipid Signaling. Affiliated tissues include eye, and related phenotype is normal.

Related Diseases for Malignant Iris Melanoma

Graphical network of the top 20 diseases related to Malignant Iris Melanoma:



Diseases related to Malignant Iris Melanoma

Symptoms & Phenotypes for Malignant Iris Melanoma

MGI Mouse Phenotypes related to Malignant Iris Melanoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 8.8 CCND1 S100A1 S100B

Drugs & Therapeutics for Malignant Iris Melanoma

Search Clinical Trials , NIH Clinical Center for Malignant Iris Melanoma

Genetic Tests for Malignant Iris Melanoma

Anatomical Context for Malignant Iris Melanoma

MalaCards organs/tissues related to Malignant Iris Melanoma:

41
Eye

Publications for Malignant Iris Melanoma

Articles related to Malignant Iris Melanoma:

# Title Authors Year
1
Ultrasound biomicroscopy in management of malignant iris melanoma. ( 12742854 )
2003

Variations for Malignant Iris Melanoma

Expression for Malignant Iris Melanoma

Search GEO for disease gene expression data for Malignant Iris Melanoma.

Pathways for Malignant Iris Melanoma

Pathways related to Malignant Iris Melanoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.73 S100A1 S100B

GO Terms for Malignant Iris Melanoma

Biological processes related to Malignant Iris Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 8.62 CCND1 S100B

Molecular functions related to Malignant Iris Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium-dependent protein binding GO:0048306 8.96 S100A1 S100B
2 S100 protein binding GO:0044548 8.62 S100A1 S100B

Sources for Malignant Iris Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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