MCID: MLG042
MIFTS: 25

Malignant Otitis Externa

Categories: Cancer diseases, Ear diseases

Aliases & Classifications for Malignant Otitis Externa

MalaCards integrated aliases for Malignant Otitis Externa:

Name: Malignant Otitis Externa 12 15 70 32

Classifications:



External Ids:

Disease Ontology 12 DOID:10516
ICD9CM 34 380.14
SNOMED-CT 67 194206006
ICD10 32 H60.2
UMLS 70 C0155395

Summaries for Malignant Otitis Externa

Disease Ontology : 12 An otitis externa which involves infection of the external ear that has spread to involve the skull bone containing part of the ear canal, the middle ear, and the inner ear. It is caused by the bacteria Pseudomonas. This is common in people with weakened immune systems and in older people with diabetes.

MalaCards based summary : Malignant Otitis Externa is related to otitis externa and mucormycosis. An important gene associated with Malignant Otitis Externa is CRP (C-Reactive Protein). Affiliated tissues include bone, heart and skin.

Related Diseases for Malignant Otitis Externa

Diseases in the Otitis Externa family:

Malignant Otitis Externa

Diseases related to Malignant Otitis Externa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 otitis externa 32.0 INS CRP
2 mucormycosis 30.3 INS CRP
3 cellulitis 30.3 INS CRP
4 osteomyelitis 10.8
5 facial paralysis 10.5
6 cranial nerve palsy 10.3
7 acquired immunodeficiency syndrome 10.3
8 otitis media 10.2
9 multiple cranial nerve palsy 10.2
10 candida glabrata 10.2
11 uvulitis 10.2 INS CRP
12 cavernous sinus thrombosis 10.2 INS CRP
13 silent myocardial infarction 10.2 INS CRP
14 neurogenic arthropathy 10.2 INS CRP
15 critical illness polyneuropathy 10.2 INS CRP
16 mediastinitis 10.2 INS CRP
17 inflammatory and toxic neuropathy 10.2 INS CRP
18 external ear disease 10.2 INS CRP
19 generalized atherosclerosis 10.2 INS CRP
20 balanitis 10.2 INS CRP
21 benign essential hypertension 10.2 INS CRP
22 acute insulin response 10.2 INS CRP
23 paralytic ileus 10.2 INS CRP
24 ileus 10.2 INS CRP
25 kwashiorkor 10.1 INS CRP
26 duodenitis 10.1 INS CRP
27 suppurative thyroiditis 10.1 INS CRP
28 thyroiditis 10.1 INS CRP
29 asphyxia neonatorum 10.1 INS CRP
30 abdominal obesity-metabolic syndrome quantitative trait locus 2 10.1 INS CRP
31 background diabetic retinopathy 10.1 INS CRP
32 decubitus ulcer 10.1 INS CRP
33 nerve compression syndrome 10.1 INS CRP
34 dysthymic disorder 10.1 INS CRP
35 nasopharyngitis 10.1 INS CRP
36 drug allergy 10.1 INS CRP
37 actinomycosis 10.1 INS CRP
38 pyelitis 10.1 INS CRP
39 lactose intolerance 10.1 INS CRP
40 chronic ulcer of skin 10.1 INS CRP
41 aspiration pneumonia 10.1 INS CRP
42 maturity-onset diabetes of the young, type 1 10.1 INS CRP
43 sphenoid sinusitis 10.1 TFF3 CRP
44 angina pectoris 10.1 INS CRP
45 coronary heart disease 1 10.1 INS CRP
46 short syndrome 10.1 INS CRP
47 apnea, obstructive sleep 10.1 INS CRP
48 intermediate coronary syndrome 10.1 INS CRP
49 sebaceous gland disease 10.1 INS CRP
50 endogenous depression 10.1 INS CRP

Graphical network of the top 20 diseases related to Malignant Otitis Externa:



Diseases related to Malignant Otitis Externa

Symptoms & Phenotypes for Malignant Otitis Externa

Drugs & Therapeutics for Malignant Otitis Externa

Search Clinical Trials , NIH Clinical Center for Malignant Otitis Externa

Genetic Tests for Malignant Otitis Externa

Anatomical Context for Malignant Otitis Externa

MalaCards organs/tissues related to Malignant Otitis Externa:

40
Bone, Heart, Skin, Bone Marrow, Eye, Thyroid, Placenta

Publications for Malignant Otitis Externa

Articles related to Malignant Otitis Externa:

(show top 50) (show all 231)
# Title Authors PMID Year
1
Malignant otitis externa: An updated review. 61
33429178 2021
2
Facial nerve paralysis in malignant otitis externa: comparison of the clinical and paraclinical findings. 61
32852248 2020
3
Clinical profiling and management outcome of atypical skull base osteomyelitis. 61
31818143 2020
4
What is the Best Test for Diagnosis and Monitoring Treatment Response in Malignant Otitis Externa? 61
32159853 2020
5
Single Application Cold-Chain Independent Drug Delivery System for Outer Ear Infections. 61
33299928 2020
6
Thirty-Day Readmission and Prolonged Length of Stay in Malignant Otitis Externa. 61
31758583 2020
7
Malignant otitis externa with subsequent internal jugular vein thrombosis and hypoglossal palsy: a report and review of literature. 61
32884563 2020
8
An emergency medicine-focused review of malignant otitis externa. 61
32505469 2020
9
Meta-analysis does not support routine traditional nuclear medicine studies for malignant otitis. 61
31750969 2020
10
Malignant Otitis Externa is Associated with Diabetes: A Population-Based Case-Control Study. 61
31976744 2020
11
Skull Base Fungal Osteomyelitis: A Case Report and Review of the Literature. 61
32584614 2020
12
Synchronous Occurrence of Bilateral Malignant Otitis Externa: Report of a Rare Case. 61
32456405 2020
13
Malignant Otitis Externa: Causes for Various Treatment Responses. 61
32209516 2020
14
Candida albicans skull base osteomyelitis due to malignant otitis externa: the role of echinocandin therapy associated with surgical debridement. 61
30981455 2020
15
Central skull base osteomyelitis secondary to invasive aspergillus sphenoid sinusitis presenting with isolated 12th nerve palsy. 61
32923366 2020
16
Candida Skull Base Osteomyelitis: a Case Report and Literature Review. 61
32771074 2020
17
C1/C2 osteomyelitis secondary to malignant otitis externa complicated by atlantoaxial subluxation-a case report and review of the literature. 61
32793861 2020
18
Extensive Skull Base Osteomyelitis Secondary to Malignant Otitis Externa. 61
30924772 2019
19
Invasive Fungal Carotiditis: A Rare Manifestation of Cranial Invasive Fungal Disease: Case Series and Systematic Review of the Literature. 61
31660355 2019
20
Stenotrophomonas skull base osteomyelitis presenting as necrotizing otitis externa: Unmasking by CT and MRI-case report and review. 61
31462947 2019
21
A population-based time trend study in the incidence of malignant otitis externa. 61
31168932 2019
22
A Unique Case of Malignant Otitis Externa. 61
31565987 2019
23
Skull base osteomyelitis: factors implicating clinical outcome. 61
30840222 2019
24
Malignant (necrotizing) externa otitis: the experience of a single hyperbaric centre. 61
31165255 2019
25
A retrospective review of 14 cases of malignant otitis externa. 61
31223303 2019
26
Herpes zoster oticus with meningitis masquerading as malignant otitis externa. 61
31177200 2019
27
Malignant otitis externa, an increasing burden in the twenty-first century: review of cases in a UK teaching hospital, with a proposed algorithm for diagnosis and management. 61
30975233 2019
28
Malignant otitis externa complicated by multiple cervical-petrous internal carotid artery pseudoaneurysms: a case report. 61
30971505 2019
29
Malignant Aspergillus flavus Otitis Externa with Jugular Thrombosis. 61
30882334 2019
30
Fungal Malignant Otitis Externa Involves a Cascade of Complications Culminating in Pseudoaneurysm of Internal Maxillary Artery: A Case Report. 61
31005959 2019
31
Nocardial clival osteomyelitis secondary to sphenoid sinusitis: an atypical skull base infection. 61
30607637 2019
32
Otitis Externa. 61
31064650 2019
33
Diabetes in the practice of otolaryngology. 61
31336457 2019
34
Malignant otitis externa in Australian Aboriginal patients: A 9-year retrospective analysis from the Northern Territory. 61
30698313 2019
35
Malignant otitis externa in a 21-year-old male patient with Prader-Willi syndrome. 61
30858975 2019
36
The Impact of using the term "Diabetic Ear" for the patients with Skull Base Osteomyelitis. 61
30697101 2019
37
The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa. 61
30464914 2018
38
A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations. 61
30459850 2018
39
Diagnosis and treatment of necrotising otitis externa and diabetic foot osteomyelitis - similarities and differences. 61
30149824 2018
40
Head and Neck Infections in Diabetic Patients. 61
31321937 2018
41
Malignant Otitis Externa Outcomes: A Study of the University HealthSystem Consortium Database. 61
29962250 2018
42
Skull base osteomyelitis secondary to Scedosporium apiospermum infection. 61
29887928 2018
43
Malignant Otitis Externa: A Retrospective Analysis and Treatment Outcomes. 61
30197809 2018
44
Chorda tympani schwannoma: one new case revealed during malignant otitis externa and review of the literature. 61
26952150 2018
45
Advanced Imaging Techniques in Skull Base Osteomyelitis Due to Malignant Otitis Externa. 61
29416952 2018
46
The treatment of pseudoaneurysms with flow diverters after malignant otitis externa. 61
28992722 2017
47
Malignant otitis externa hospitalizations: Analysis of patient characteristics. 61
27882553 2017
48
A Treatment Protocol for Management of Bacterial and Fungal Malignant External Otitis: A Large Cohort in Tehran, Iran. 61
28528568 2017
49
Skull base osteomyelitis secondary to malignant otitis externa mimicking advanced nasopharyngeal cancer: MR imaging features at initial presentation. 61
28483146 2017
50
Fungal malignant otitis externa. 61
28348261 2017

Variations for Malignant Otitis Externa

Expression for Malignant Otitis Externa

Search GEO for disease gene expression data for Malignant Otitis Externa.

Pathways for Malignant Otitis Externa

GO Terms for Malignant Otitis Externa

Biological processes related to Malignant Otitis Externa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.62 INS CRP

Sources for Malignant Otitis Externa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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