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MCID: MLG042
MIFTS: 25

Malignant Otitis Externa

Categories: Ear diseases
Genes Tissues Related diseases Publications
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Aliases & Classifications for Malignant Otitis Externa

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MalaCards integrated aliases for Malignant Otitis Externa:

Name: Malignant Otitis Externa 12 15 71 32

Classifications:

MalaCards categories:
Anatomical: Ear diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:10516
ICD9CM 34 380.14
SNOMED-CT 67 94146005
ICD10 32 H60.2
UMLS 71 C0155395
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Summaries for Malignant Otitis Externa

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Disease Ontology : 12 An otitis externa which involves infection of the external ear that has spread to involve the skull bone containing part of the ear canal, the middle ear, and the inner ear. It is caused by the bacteria Pseudomonas. This is common in people with weakened immune systems and in older people with diabetes.

MalaCards based summary : Malignant Otitis Externa is related to mucormycosis and otitis externa. An important gene associated with Malignant Otitis Externa is CRP (C-Reactive Protein). Affiliated tissues include bone, skin and bone marrow.

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Related Diseases for Malignant Otitis Externa

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Diseases in the Otitis Externa family:

Malignant Otitis Externa

Diseases related to Malignant Otitis Externa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 mucormycosis 30.4 INS CRP
2 otitis externa 11.2
3 osteomyelitis 10.8
4 facial paralysis 10.5
5 acquired immunodeficiency syndrome 10.3
6 cranial nerve palsy 10.3
7 neurogenic arthropathy 10.2 INS CRP
8 silent myocardial infarction 10.2 INS CRP
9 critical illness polyneuropathy 10.2 INS CRP
10 acute insulin response 10.2 INS CRP
11 diabetes mellitus 10.2
12 candida glabrata 10.2
13 squamous cell carcinoma 10.2
14 multiple cranial nerve palsy 10.2
15 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
16 human immunodeficiency virus type 1 10.2
17 otitis media 10.2
18 inflammatory and toxic neuropathy 10.2 INS CRP
19 generalized atherosclerosis 10.2 INS CRP
20 mediastinitis 10.2 INS CRP
21 duodenitis 10.2 INS CRP
22 kwashiorkor 10.2 INS CRP
23 abdominal obesity-metabolic syndrome quantitative trait locus 2 10.2 INS CRP
24 background diabetic retinopathy 10.2 INS CRP
25 asphyxia neonatorum 10.2 INS CRP
26 nerve compression syndrome 10.2 INS CRP
27 decubitus ulcer 10.2 INS CRP
28 nasopharyngitis 10.2 INS CRP
29 drug allergy 10.2 INS CRP
30 actinomycosis 10.2 INS CRP
31 lactose intolerance 10.2 INS CRP
32 maturity-onset diabetes of the young, type 1 10.2 INS CRP
33 chronic ulcer of skin 10.2 INS CRP
34 angina pectoris 10.2 INS CRP
35 short syndrome 10.2 INS CRP
36 intermediate coronary syndrome 10.2 INS CRP
37 adult syndrome 10.2 INS CRP
38 sebaceous gland disease 10.2 INS CRP
39 apnea, obstructive sleep 10.2 INS CRP
40 hypercholesterolemia, familial, 1 10.1 INS CRP
41 prediabetes syndrome 10.1 INS CRP
42 hernia, hiatus 10.1 ISLR2 CRP
43 vein disease 10.1 INS CRP
44 laryngitis 10.1 ISLR2 CRP
45 mineral metabolism disease 10.1 INS CRP
46 anovulation 10.1 INS CRP
47 acute cystitis 10.1 INS CRP
48 autoimmune disease of gastrointestinal tract 10.1 INS CRP
49 cholelithiasis 10.1 INS CRP
50 pneumonia 10.1

Graphical network of the top 20 diseases related to Malignant Otitis Externa:



Diseases related to Malignant Otitis Externa
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Symptoms & Phenotypes for Malignant Otitis Externa

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Drugs & Therapeutics for Malignant Otitis Externa

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Search Clinical Trials , NIH Clinical Center for Malignant Otitis Externa

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Genetic Tests for Malignant Otitis Externa

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Anatomical Context for Malignant Otitis Externa

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MalaCards organs/tissues related to Malignant Otitis Externa:

40
Bone, Skin, Bone Marrow, Eye, Testes, Neutrophil
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Publications for Malignant Otitis Externa

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Articles related to Malignant Otitis Externa:

(show top 50) (show all 223)
# Title Authors PMID Year
1
Meta-analysis does not support routine traditional nuclear medicine studies for malignant otitis. 61
31750969 2020
2
Malignant Otitis Externa is Associated with Diabetes: A Population-Based Case-Control Study. 61
31976744 2020
3
Synchronous Occurrence of Bilateral Malignant Otitis Externa: Report of a Rare Case. 61
32456405 2020
4
Malignant Otitis Externa: Causes for Various Treatment Responses. 61
32209516 2020
5
An emergency medicine-focused review of malignant otitis externa. 61
32505469 2020
6
What is the Best Test for Diagnosis and Monitoring Treatment Response in Malignant Otitis Externa? 61
32159853 2020
7
Candida albicans skull base osteomyelitis due to malignant otitis externa: the role of echinocandin therapy associated with surgical debridement. 61
30981455 2020
8
Extensive Skull Base Osteomyelitis Secondary to Malignant Otitis Externa. 61
30924772 2019
9
Clinical profiling and management outcome of atypical skull base osteomyelitis. 61
31818143 2019
10
Thirty-Day Readmission and Prolonged Length of Stay in Malignant Otitis Externa. 61
31758583 2019
11
Stenotrophomonas skull base osteomyelitis presenting as necrotizing otitis externa: Unmasking by CT and MRI-case report and review. 61
31462947 2019
12
Invasive Fungal Carotiditis: A Rare Manifestation of Cranial Invasive Fungal Disease: Case Series and Systematic Review of the Literature. 61
31660355 2019
13
Skull base osteomyelitis: factors implicating clinical outcome. 61
30840222 2019
14
A Unique Case of Malignant Otitis Externa. 61
31565987 2019
15
A population-based time trend study in the incidence of malignant otitis externa. 61
31168932 2019
16
Malignant (necrotizing) externa otitis: the experience of a single hyperbaric centre. 61
31165255 2019
17
A retrospective review of 14 cases of malignant otitis externa. 61
31223303 2019
18
Herpes zoster oticus with meningitis masquerading as malignant otitis externa. 61
31177200 2019
19
Malignant otitis externa, an increasing burden in the twenty-first century: review of cases in a UK teaching hospital, with a proposed algorithm for diagnosis and management. 61
30975233 2019
20
Malignant otitis externa complicated by multiple cervical-petrous internal carotid artery pseudoaneurysms: a case report. 61
30971505 2019
21
Malignant Aspergillus flavus Otitis Externa with Jugular Thrombosis. 61
30882334 2019
22
Fungal Malignant Otitis Externa Involves a Cascade of Complications Culminating in Pseudoaneurysm of Internal Maxillary Artery: A Case Report. 61
31005959 2019
23
Otitis Externa. 61
31064650 2019
24
Nocardial clival osteomyelitis secondary to sphenoid sinusitis: an atypical skull base infection. 61
30607637 2019
25
Diabetes in the practice of otolaryngology. 61
31336457 2019
26
Malignant otitis externa in Australian Aboriginal patients: A 9-year retrospective analysis from the Northern Territory. 61
30698313 2019
27
The Impact of using the term "Diabetic Ear" for the patients with Skull Base Osteomyelitis. 61
30697101 2019
28
Malignant otitis externa in a 21-year-old male patient with Prader-Willi syndrome. 61
30858975 2019
29
The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa. 61
30464914 2018
30
A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations. 61
30459850 2018
31
Diagnosis and treatment of necrotising otitis externa and diabetic foot osteomyelitis - similarities and differences. 61
30149824 2018
32
Head and Neck Infections in Diabetic Patients. 61
31321937 2018
33
Malignant Otitis Externa Outcomes: A Study of the University HealthSystem Consortium Database. 61
29962250 2018
34
Skull base osteomyelitis secondary to Scedosporium apiospermum infection. 61
29887928 2018
35
Malignant Otitis Externa: A Retrospective Analysis and Treatment Outcomes. 61
30197809 2018
36
Chorda tympani schwannoma: one new case revealed during malignant otitis externa and review of the literature. 61
26952150 2018
37
Advanced Imaging Techniques in Skull Base Osteomyelitis Due to Malignant Otitis Externa. 61
29416952 2018
38
The treatment of pseudoaneurysms with flow diverters after malignant otitis externa. 61
28992722 2017
39
Malignant otitis externa hospitalizations: Analysis of patient characteristics. 61
27882553 2017
40
Skull base osteomyelitis secondary to malignant otitis externa mimicking advanced nasopharyngeal cancer: MR imaging features at initial presentation. 61
28483146 2017
41
A Treatment Protocol for Management of Bacterial and Fungal Malignant External Otitis: A Large Cohort in Tehran, Iran. 61
28528568 2017
42
Fungal malignant otitis externa. 61
28348261 2017
43
Is malignant otitis externa on the increase? A retrospective review of cases. 61
28231368 2017
44
Scedosporium apiospermum: a rare cause of malignant otitis externa. 61
27613266 2016
45
Malignant otitis externa in a healthy non-diabetic patient. 61
26233245 2016
46
Recurrent malignant otitis externa with multiple cranial nerve involvement: A case report. 61
29648753 2016
47
Skull Base Osteomyelitis Caused by an Elegant Fungus. 61
27730788 2016
48
A Case of Skull Base Osteomyelitis with Multiple Cerebral Infarction. 61
27597916 2016
49
[Malignant otitis externa caused by Candida albicans]. 61
28154677 2016
50
Malignant Otitis Externa and Stroke. 61
30755871 2016
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Variations for Malignant Otitis Externa

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Expression for Malignant Otitis Externa

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Search GEO for disease gene expression data for Malignant Otitis Externa.
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Pathways for Malignant Otitis Externa

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GO Terms for Malignant Otitis Externa

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Biological processes related to Malignant Otitis Externa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.96 INS CRP
2 negative regulation of blood vessel diameter GO:0097756 8.62 INS CRP
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Sources for Malignant Otitis Externa

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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