MCID: MLG053
MIFTS: 18

Malignant Ovarian Brenner Tumor

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Malignant Ovarian Brenner Tumor

MalaCards integrated aliases for Malignant Ovarian Brenner Tumor:

Name: Malignant Ovarian Brenner Tumor 12 15
Malignant Brenner Tumor 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4217
MeSH 44 D001948
NCIt 50 C4270
SNOMED-CT 68 42194009
UMLS 73 C0334495

Summaries for Malignant Ovarian Brenner Tumor

Disease Ontology : 12 A malignant ovarian surface epithelial-stromal neoplasm that has material basis in the surface epithelium of the ovary.

MalaCards based summary : Malignant Ovarian Brenner Tumor, also known as malignant brenner tumor, is related to ovarian brenner tumor. An important gene associated with Malignant Ovarian Brenner Tumor is SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1). The drugs Carotenoids and Micronutrients have been mentioned in the context of this disorder. Affiliated tissues include ovary, cervix and testis.

Related Diseases for Malignant Ovarian Brenner Tumor

Diseases in the Ovarian Brenner Tumor family:

Malignant Ovarian Brenner Tumor

Diseases related to Malignant Ovarian Brenner Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ovarian brenner tumor 10.2

Symptoms & Phenotypes for Malignant Ovarian Brenner Tumor

Drugs & Therapeutics for Malignant Ovarian Brenner Tumor

Drugs for Malignant Ovarian Brenner Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Carotenoids Phase 3
2 Micronutrients Phase 3
3 Trace Elements Phase 3
4
Iodine Approved, Investigational Phase 1, Phase 2 7553-56-2 807
5
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
6
Bevacizumab Approved, Investigational Phase 2 216974-75-3
7
Carboplatin Approved Phase 2 41575-94-4 10339178 38904 498142
8 Antineoplastic Agents, Phytogenic Phase 2
9 Antimitotic Agents Phase 2
10 Immunologic Factors Phase 2
11 Immunoglobulins Phase 2
12 Angiogenesis Modulating Agents Phase 2
13 Angiogenesis Inhibitors Phase 2
14 Antibodies Phase 2
15 Albumin-Bound Paclitaxel Phase 2
16 Antibodies, Monoclonal Phase 2
17 Endothelial Growth Factors Phase 2
18 Immunoglobulin G Phase 2
19 Mitogens Phase 2
20 CHI3L1 protein, human

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Recruiting NCT00719303 Phase 3
2 MV-NIS Infected Mesenchymal Stem Cells in Treating Patients With Recurrent Ovarian Cancer Recruiting NCT02068794 Phase 1, Phase 2
3 Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Recruiting NCT02923739 Phase 2 Paclitaxel
4 First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer Active, not recruiting NCT01097746 Phase 2 Carboplatin;Paclitaxel
5 The Effects of Moderate Exercise on Distress, Quality of Life, and Biomarkers of Angiogenesis and Chronic Stress in Ovarian Cancer Survivors Recruiting NCT03641287 Not Applicable
6 YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Receiving Chemotherapy Terminated NCT00899093

Search NIH Clinical Center for Malignant Ovarian Brenner Tumor

Genetic Tests for Malignant Ovarian Brenner Tumor

Anatomical Context for Malignant Ovarian Brenner Tumor

MalaCards organs/tissues related to Malignant Ovarian Brenner Tumor:

41
Ovary, Cervix, Testis

Publications for Malignant Ovarian Brenner Tumor

Articles related to Malignant Ovarian Brenner Tumor:

(show all 48)
# Title Authors Year
1
Malignant Brenner tumor: Two case reports. ( 30364765 )
2018
2
Malignant Brenner tumor associated with a germline BRCA2 mutation. ( 28616458 )
2017
3
Malignant Brenner tumor of the ovary: Review and case report. ( 28971141 )
2017
4
Laparoscopic treatment of Castleman's disease in a patient with a history of malignant Brenner tumor. ( 27751433 )
2016
5
Malignant ovarian Brenner tumor. A case report evaluated with (18)F-FDG PET/CT. ( 25890890 )
2015
6
Intensive systemic chemotherapy is effective against recurrent malignant Brenner tumor of the ovary: An analysis of 10 cases within a single center. ( 25951724 )
2015
7
Ovarian malignant Brenner tumor in patients over 65 years of age. ( 24581217 )
2014
8
Malignant Brenner tumor of the ovary: analysis of 13 cases. ( 21796330 )
2012
9
Malignant Brenner tumor of the ovary with transformation to trabecular carcinoid: an immunocytochemical and electron microscopic study. ( 22123728 )
2012
10
Diffusion-weighted imaging of a malignant brenner tumor. ( 22450390 )
2012
11
Ascitic fluid cytology in malignant Brenner tumor: a case report. ( 20715663 )
2010
12
Malignant Brenner tumor with transition from benign to malignant components: computed tomographic and magnetic resonance imaging findings with pathological correlation. ( 18664841 )
2008
13
Chromosomal aberrations in ovarian malignant brenner tumor cell line using chromosome painting. ( 10748297 )
2000
14
An unusual case of malignant Brenner tumor in association with low-grade urothelial carcinoma of the urinary bladder. A case report. ( 10475132 )
1999
15
Malignant Brenner tumor mimicking a primary squamous cell carcinoma of the cervix. ( 10479516 )
1999
16
Cytology of ascitic fluid in a patient with metastasizing malignant Brenner tumor of the ovary. A case report. ( 9990262 )
1997
17
Case report of a malignant Brenner tumor with hyperestrogenism. ( 7704247 )
1995
18
Fine needle aspiration cytology of a subcutaneous metastasis of a malignant Brenner tumor of the ovary. A case report. ( 7887072 )
1995
19
Malignant Brenner tumor of the ovary: two cases of unusual histologic features of relapsed tumors. ( 8590361 )
1995
20
Malignant Brenner tumor: a case of aggressive clinical course and cutaneous metastases. ( 7798842 )
1994
21
Malignant Brenner tumor: MR findings. ( 1950890 )
1991
22
Malignant Brenner tumor of the testis and epididymis. ( 2021324 )
1991
23
Ultrastructure of malignant Brenner tumor of the ovary. ( 2123778 )
1990
24
Malignant Brenner tumor of the ovary. ( 3057285 )
1988
25
Malignant Brenner tumor and transitional cell carcinoma of the ovary: a comparison. ( 3570630 )
1987
26
Malignant Brenner tumor with peritoneal metastasis. ( 3661200 )
1987
27
Estrogen synthesizing rare malignant Brenner tumor of the ovary with the presence of progesterone and androgen receptors in the absence of estrogen receptors. ( 3804043 )
1987
28
The histologic features and histogenesis of malignant ovarian Brenner tumor. ( 3100186 )
1986
29
Malignant Brenner tumor. A histologic, morphometrical, immunohistochemical, and ultrastructural study. ( 2425924 )
1986
30
Bilateral malignant Brenner tumor. A light and electron microscopic study. ( 6464760 )
1984
31
Retroperitoneal metastatic spread of malignant Brenner tumor. ( 6526339 )
1984
32
Bilateral malignant Brenner tumor of the ovary. ( 6738070 )
1984
33
Malignant Brenner tumor of the ovary. Electron microscopic study of a case responsive to radiation and chemotherapy. ( 6821829 )
1983
34
Malignant Brenner tumor of the ovary. A case report: negative second look laparotomy following surgery, radiation ad chemotherapy. ( 6125438 )
1982
35
Bilateral malignant Brenner tumor: report of a case with ultrastructural study. ( 7203458 )
1981
36
Malignant Brenner tumor of the ovary. Report of three cases. ( 7215126 )
1981
37
Malignant Brenner tumor of the ovary: case report with a review of the literature. ( 369079 )
1978
38
Malignant Brenner tumor of the ovary. ( 669445 )
1978
39
Letter: Malignant Brenner tumor. ( 4474643 )
1974
40
The malignant Brenner tumor. ( 4742657 )
1973
41
Malignant Brenner tumor--a case report. ( 4800576 )
1973
42
Malignant Brenner tumor. ( 5962960 )
1966
43
MALIGNANT BRENNER TUMOR ASSOCIATED WITH ENDOMETRIAL ADENOCARCINOMA. ( 14043280 )
1963
44
Malignant Brenner tumor. ( 13633130 )
1959
45
Malignant Brenner tumor of the ovary; with the report of one case. ( 13583031 )
1958
46
Malignant Brenner tumor. ( 13443639 )
1957
47
Malignant Brenner tumor; report of a case. ( 13469881 )
1957
48
Malignant Brenner tumor; report of a case. ( 13228516 )
1955

Variations for Malignant Ovarian Brenner Tumor

Expression for Malignant Ovarian Brenner Tumor

Search GEO for disease gene expression data for Malignant Ovarian Brenner Tumor.

Pathways for Malignant Ovarian Brenner Tumor

GO Terms for Malignant Ovarian Brenner Tumor

Sources for Malignant Ovarian Brenner Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....