MCID: MLG033
MIFTS: 19

Malignant Ovarian Cyst

Categories: Endocrine diseases, Reproductive diseases, Cancer diseases

Aliases & Classifications for Malignant Ovarian Cyst

MalaCards integrated aliases for Malignant Ovarian Cyst:

Name: Malignant Ovarian Cyst 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2145
NCIt 50 C3843
UMLS 73 C0235770

Summaries for Malignant Ovarian Cyst

MalaCards based summary : Malignant Ovarian Cyst is related to ovarian cyst and ovarian cancer. An important gene associated with Malignant Ovarian Cyst is MET (MET Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotype is cardiovascular system.

Related Diseases for Malignant Ovarian Cyst

Diseases in the Ovarian Cyst family:

Malignant Ovarian Cyst

Diseases related to Malignant Ovarian Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ovarian cyst 10.1
2 ovarian cancer 9.7
3 placenta disease 9.7
4 insulin-like growth factor i 9.5 IGF1 IGFBP2
5 anorexia nervosa 9.3 IGF1 IGFBP2

Graphical network of the top 20 diseases related to Malignant Ovarian Cyst:



Diseases related to Malignant Ovarian Cyst

Symptoms & Phenotypes for Malignant Ovarian Cyst

MGI Mouse Phenotypes related to Malignant Ovarian Cyst:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.92 FUT4 IGF1 IGFBP2 MET

Drugs & Therapeutics for Malignant Ovarian Cyst

Search Clinical Trials , NIH Clinical Center for Malignant Ovarian Cyst

Genetic Tests for Malignant Ovarian Cyst

Anatomical Context for Malignant Ovarian Cyst

Publications for Malignant Ovarian Cyst

Articles related to Malignant Ovarian Cyst:

# Title Authors Year
1
Pregnancy with malignant ovarian cyst in 25-year-old female. ( 25404813 )
2014
2
Apolipoprotein concentrations are elevated in malignant ovarian cyst fluids suggesting that lipoprotein metabolism is dysregulated in epithelial ovarian cancer. ( 23627408 )
2013
3
Collagenases (MMP-1, -8 and -13) and trypsinogen-2 in fluid from benign and malignant ovarian cysts. ( 12743421 )
2003
4
Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid. ( 8624265 )
1996
5
Placental protein 5 in benign and malignant ovarian cyst fluids. ( 3448769 )
1987
6
Placental protein 10: levels in benign and malignant ovarian cyst fluids and pleural exudates. ( 3566356 )
1987
7
Pregnancy complicated by a malignant ovarian cyst. ( 15422432 )
1950

Variations for Malignant Ovarian Cyst

Expression for Malignant Ovarian Cyst

Search GEO for disease gene expression data for Malignant Ovarian Cyst.

Pathways for Malignant Ovarian Cyst

GO Terms for Malignant Ovarian Cyst

Cellular components related to Malignant Ovarian Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 8.92 IGF1 IGFBP2 MET TFPI2

Biological processes related to Malignant Ovarian Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of MAPK cascade GO:0043410 9.16 IGF1 MET
2 response to insulin GO:0032868 8.96 IGF1 IGFBP2
3 positive regulation of activated T cell proliferation GO:0042104 8.62 IGF1 IGFBP2

Sources for Malignant Ovarian Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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