MCID: MLG022
MIFTS: 20

Malignant Sertoli Cell Tumor

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Malignant Sertoli Cell Tumor

MalaCards integrated aliases for Malignant Sertoli Cell Tumor:

Name: Malignant Sertoli Cell Tumor 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:0050617
UMLS 72 C0334406

Summaries for Malignant Sertoli Cell Tumor

Disease Ontology : 12 A sex cord-gonadal stromal tumor characterized by excessive proliferation of Sertoli cells located in the seminiferous tubules of the testicles.

MalaCards based summary : Malignant Sertoli Cell Tumor is related to sex cord-gonadal stromal tumor and large cell neuroendocrine carcinoma. An important gene associated with Malignant Sertoli Cell Tumor is AFP (Alpha Fetoprotein). Affiliated tissues include testis, ovary and lung.

Related Diseases for Malignant Sertoli Cell Tumor

Diseases in the Sertoli Cell Tumor family:

Malignant Sertoli Cell Tumor

Diseases related to Malignant Sertoli Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
# Related Disease Score Top Affiliating Genes
1 sex cord-gonadal stromal tumor 30.1 SYP AFP
2 large cell neuroendocrine carcinoma 29.9 SYP ENO2
3 testicular cancer 29.8 CGB5 AFP
4 seminoma 29.4 ENO2 CGB5 AFP
5 sertoli cell tumor 10.6
6 mediastinal cancer 10.2 SYP AFP
7 male reproductive organ benign neoplasm 10.2 SYP AFP
8 seminal vesicle tumor 10.2 SYP AFP
9 pancreatoblastoma 10.2 SYP AFP
10 pineoblastoma 10.2 SYP AFP
11 nonseminomatous germ cell tumor 10.2 CGB5 AFP
12 corpus luteum cyst 10.2 CGB5 AFP
13 extragonadal germ cell cancer 10.2 CGB5 AFP
14 tubular adenocarcinoma 10.1 SYP AFP
15 placenta disease 10.0 CGB5 AFP
16 small cell carcinoma 10.0 SYP ENO2
17 neuroendocrine carcinoma 10.0
18 embryonal carcinoma 10.0
19 rare tumor 10.0
20 carotid body cancer 10.0 SYP ENO2
21 urinary bladder small cell neuroendocrine carcinoma 10.0 SYP ENO2
22 auditory system cancer 10.0 SYP ENO2
23 melanotic medulloblastoma 10.0 ENO2 AFP
24 sinonasal undifferentiated carcinoma 10.0 SYP ENO2
25 papillary tumor of the pineal region 10.0 SYP ENO2
26 small cell carcinoma of the bladder 10.0 SYP ENO2
27 extrahepatic bile duct adenocarcinoma 10.0 SYP ENO2
28 cutaneous ganglioneuroma 10.0 SYP ENO2
29 ganglioneuroma 10.0 SYP ENO2
30 pancreatic somatostatinoma 10.0 SYP ENO2
31 middle ear adenoma 10.0 SYP ENO2
32 endocrine gland cancer 10.0 SYP AFP
33 orbital cancer 10.0 SYP ENO2
34 sensory organ benign neoplasm 10.0 SYP ENO2
35 atypical follicular adenoma 10.0 SYP ENO2
36 gallbladder small cell carcinoma 10.0 SYP ENO2
37 pulmonary large cell neuroendocrine carcinoma 10.0 SYP ENO2
38 clear cell ependymoma 10.0 SYP ENO2
39 ependymoma 10.0 SYP ENO2
40 cerebellum cancer 10.0 SYP ENO2
41 central nervous system primitive neuroectodermal neoplasm 10.0 SYP ENO2
42 cauda equina neoplasm 10.0 SYP ENO2
43 cerebral neuroblastoma 9.9 SYP ENO2
44 astroblastoma 9.9 SYP ENO2
45 subependymal glioma 9.9 SYP ENO2
46 extraosseous chondrosarcoma 9.9 SYP ENO2
47 pineal gland cancer 9.9 SYP ENO2
48 olfactory nerve neoplasm 9.9 SYP ENO2
49 cerebral ventricle cancer 9.9 SYP ENO2
50 nodular ganglioneuroblastoma 9.9 SYP ENO2

Graphical network of the top 20 diseases related to Malignant Sertoli Cell Tumor:



Diseases related to Malignant Sertoli Cell Tumor

Symptoms & Phenotypes for Malignant Sertoli Cell Tumor

Drugs & Therapeutics for Malignant Sertoli Cell Tumor

Search Clinical Trials , NIH Clinical Center for Malignant Sertoli Cell Tumor

Genetic Tests for Malignant Sertoli Cell Tumor

Anatomical Context for Malignant Sertoli Cell Tumor

MalaCards organs/tissues related to Malignant Sertoli Cell Tumor:

41
Testis, Ovary, Lung, Bone

The Foundational Model of Anatomy Ontology organs/tissues related to Malignant Sertoli Cell Tumor:

19
Seminiferous Tubules Of The Testicles

Publications for Malignant Sertoli Cell Tumor

Articles related to Malignant Sertoli Cell Tumor:

(show all 19)
# Title Authors PMID Year
1
Malignant Sertoli cell tumor of the testis masquerading as seminoma with bone metastasis. 38
30303161 2018
2
A spontaneously occurring malignant ovarian Sertoli cell tumor in a young Sprague Dawley rat. 38
26989303 2016
3
Malignant sertoli cell tumor in a goose (Anser cygnoides domesticus). 38
23397858 2012
4
Malignant sertoli cell tumor of the testis with a large retroperitoneal mass in an elderly man. 38
21170861 2010
5
[Sertoli cell malignant tumor]. 38
18972923 2008
6
[Case report of malignant sertoli cell tumor]. 38
18697473 2008
7
Metastatic ovarian Sertoli-cell tumor: FNA findings with immunohistochemistry. 38
14595797 2003
8
Malignant Sertoli cell tumor in the retained abdominal testis of a unilaterally cryptorchid horse. 38
12597422 2003
9
Case report: malignant Sertoli cell tumor of the testis in an adult. 38
15198158 2003
10
Malignant Sertoli cell tumor of the ovary metastatic to the lung mimicking neuroendocrine carcinoma: report of a case. 38
10459047 1999
11
Malignant Sertoli cell tumor in a prepubescent boy. 38
9224377 1997
12
Malignant Sertoli cell tumor of the testicle in a black man. 38
8965335 1996
13
Fine needle aspiration cytology in malignant Sertoli cell tumor of the testis. A case report. 38
1636354 1992
14
[A case of malignant Sertoli cell tumor of the testis]. 38
3586350 1987
15
Malignant Sertoli cell tumor of testicle. 38
4024415 1985
16
[Malignant Sertoli cell tumor of the testis]. 38
6485954 1984
17
[Malignant Sertoli cell tumor (malignant androblastoma)]. 38
6672514 1983
18
Malignant sertoli cell tumor of the testis. 38
5566364 1971
19
Malignant Sertoli cell tumor of the testis. 38
5659417 1968

Variations for Malignant Sertoli Cell Tumor

Expression for Malignant Sertoli Cell Tumor

Search GEO for disease gene expression data for Malignant Sertoli Cell Tumor.

Pathways for Malignant Sertoli Cell Tumor

GO Terms for Malignant Sertoli Cell Tumor

Sources for Malignant Sertoli Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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