MTT
MCID: MLG041
MIFTS: 32

Malignant Triton Tumor (MTT)

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Malignant Triton Tumor

MalaCards integrated aliases for Malignant Triton Tumor:

Name: Malignant Triton Tumor 12 58 15
Malignant Peripheral Nerve Sheath Tumor with Rhabdomyosarcomatous Differenciation 58
Malignant Peripheral Nerve Sheath Tumor with Rhabdomyoblastic Differentiation 71
Malignant Peripheral Nerve Sheath Neoplasm with Rhabdomyosarcoma 12
Mpnst with Rhabdomyosarcomatous Differentiation 58
Mpnst with Rhabdomyoblastic Differentiation 12
Mpnst with Rhabdomyosarcoma 12
Malignant Triton Tumour 12
Mtt 58

Characteristics:

Orphanet epidemiological data:

58
malignant triton tumor
Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:6707
NCIt 49 C4335
SNOMED-CT 67 354002
UMLS via Orphanet 72 C0334616
Orphanet 58 ORPHA252212
UMLS 71 C0334616

Summaries for Malignant Triton Tumor

MalaCards based summary : Malignant Triton Tumor, also known as malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differenciation, is related to neurofibrosarcoma and malignant peripheral nerve sheath tumor. An important gene associated with Malignant Triton Tumor is MB (Myoglobin), and among its related pathways/superpathways is Mesenchymal Stem Cells and Lineage-specific Markers. Affiliated tissues include lung, small intestine and thyroid, and related phenotype is respiratory system.

Wikipedia : 74 Malignant triton tumor (MTT) is a relatively rare, aggressive tumor made up of both malignant schwannoma... more...

Related Diseases for Malignant Triton Tumor

Diseases related to Malignant Triton Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 316)
# Related Disease Score Top Affiliating Genes
1 neurofibrosarcoma 32.3 NF1 ENO2
2 malignant peripheral nerve sheath tumor 31.6 S100B NF1 MYOG MLANA B3GAT1
3 neurofibroma 30.6 S100B NF1 MLANA
4 adenosarcoma 30.3 MB DES
5 spindle cell sarcoma 30.3 S100B MYOG DES
6 liposarcoma 30.1 MYOG MB DES
7 neurilemmoma 29.9 S100B NF1 MLANA ENO2 DES
8 gas gangrene 29.8 MYOG MYOD1 MB
9 botryoid rhabdomyosarcoma 29.6 MYOG MYOD1 MB DES
10 malignant mesenchymoma 29.6 MYOG MYOD1 MB DES
11 fibrous histiocytoma 29.6 S100B MYOG ENO2 DES
12 embryonal rhabdomyosarcoma 29.6 MYOG MYOD1 MB DES
13 malignant fibrous histiocytoma 29.3 S100B MYOG MYOD1 MB DES
14 rhabdomyosarcoma 29.3 S100B MYOG MYOD1 MB ENO2 DES
15 sarcoma 29.0 S100B MYOG MYOD1 ENO2 DES
16 sarcoma, synovial 28.8 TLE1 S100B NF1 MYOG DES
17 medulloblastoma 28.5 S100B NF1 MYOG MYOD1 ENO2 DES
18 hemangiopericytoma, malignant 27.9 TLE1 S100B MYOG MLANA ENO2 DES
19 neurofibromatosis 10.8
20 rare tumor 10.4
21 giant cell myocarditis 10.4 MB DES
22 malignant giant cell tumor of soft parts 10.4 S100B MB
23 cutaneous leiomyosarcoma 10.3 S100B DES
24 syringocystadenoma papilliferum 10.3 S100B DES
25 pituitary tumors 10.3
26 neurofibromatosis, type i 10.3
27 myeloid leukemia 10.3
28 inflammatory leiomyosarcoma 10.3 MYOG DES
29 cervical polyp 10.3 MYOG DES
30 glioma 10.3
31 glial tumor 10.3
32 malignant fibrous histiocytoma of bone 10.3 MYOD1 DES
33 pleomorphic liposarcoma 10.3 S100B DES
34 intracranial cysts 10.2 S100B ENO2
35 bednar tumor 10.2 S100B ENO2
36 epididymal neoplasm 10.2 NF1 MYOD1
37 gastric cancer 10.2
38 acute leukemia 10.2
39 head injury 10.2 S100B ENO2
40 papillary ependymoma 10.2 S100B ENO2
41 infantile myofibromatosis 10.2 MB DES
42 kidney rhabdoid cancer 10.2 MB ENO2
43 primitive neuroectodermal tumor of the cervix uteri 10.2 ENO2 DES
44 pineocytoma 10.2 S100B ENO2
45 undifferentiated embryonal sarcoma of the liver 10.2 MYOG MYOD1
46 breast leiomyosarcoma 10.2 MB ENO2
47 conventional leiomyosarcoma 10.2 MYOG MYOD1
48 prostate embryonal rhabdomyosarcoma 10.2 MYOG MYOD1
49 spindle cell thymoma 10.2 ENO2 DES
50 congenital epulis 10.2 ENO2 DES

Graphical network of the top 20 diseases related to Malignant Triton Tumor:



Diseases related to Malignant Triton Tumor

Symptoms & Phenotypes for Malignant Triton Tumor

MGI Mouse Phenotypes related to Malignant Triton Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.02 ENO2 MB MYOD1 MYOG NF1

Drugs & Therapeutics for Malignant Triton Tumor

Search Clinical Trials , NIH Clinical Center for Malignant Triton Tumor

Genetic Tests for Malignant Triton Tumor

Anatomical Context for Malignant Triton Tumor

MalaCards organs/tissues related to Malignant Triton Tumor:

40
Lung, Small Intestine, Thyroid, Spinal Cord, Kidney

Publications for Malignant Triton Tumor

Articles related to Malignant Triton Tumor:

(show top 50) (show all 120)
# Title Authors PMID Year
1
Worsening Hemoptysis in a Rare Intrapulmonary Triton Tumor Mimicking Lung Cancer. 61
31400331 2020
2
[Focus on oncologic safety and function: Primary defect reconstruction of a malignant Triton tumor of the sciatic nerve sheath with myocutaneous free flap surgery]. 61
32120413 2020
3
Triton tumor of the orbit. 61
31746248 2019
4
Malignant Triton Tumor Diagnosed on Fine Needle Aspiration Cytology. 61
31741582 2019
5
A series of 10 malignant triton tumors in one institution. 61
31490366 2019
6
Malignant triton tumor diagnosed twelve years after radiosurgically treated vestibular schwannoma. 61
31176932 2019
7
Malignant triton tumor of the left thoracic cavity: a case report. 61
31528328 2019
8
Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor. 61
28924675 2019
9
Expert's comment concerning Grand Rounds case entitled "Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor" by S. Ghailane et al. (Eur Spine J; 2017: DOI 10.1007/s00586-017-5277-2). 61
29671111 2019
10
Teaching NeuroImages: Intracranial malignant triton tumor: An uncommon location of a rare tumor. 61
30886081 2019
11
Mediastinal malignant triton tumor: A rare case series and review of literature. 61
31494456 2019
12
Malignant Triton Tumor in a Child: Case Report and Literature Review. 61
31920385 2019
13
Malignant triton tumor of trigeminal nerve-case report. 61
29279963 2018
14
Malignant triton tumor of the gluteal region in a patient unaffected by neurofibromatosis: A case report. 61
29110923 2018
15
Malignant triton tumor of the duodenum: report of a case. 61
31149515 2018
16
A rare case of intracranial malignant triton tumor arising in the middle cranial fossa: a case report and review of the literature. 61
30509044 2018
17
[A Rare Case of Abdominal Malignant Triton Tumor]. 61
29394776 2017
18
Malignant Triton Tumor (Malignant Peripheral Nerve Sheath Tumor With Rhabdomyoblastic Differentiation) Occurring in a Vascularized Free Flap Reconstruction Graft. 61
28387148 2017
19
A Case of Retroperitoneal Malignant Triton Tumor in a Nigerian Boy. 61
29089742 2017
20
Malignant Triton tumor: a rare cause of sciatic pain and foot drop. 61
28884110 2017
21
Malignant triton tumor of the lung, infiltrating the left atrium and left ventricle, with metastasis to the small intestine. 61
28515751 2017
22
Malignant Triton Tumor of the Kidney. New Location Not Previously Reported. 61
26159374 2017
23
A case of recurrent malignant triton tumor successfully treated with radiotherapy. 61
27146005 2016
24
Insidious malignant triton tumor of the chest wall with late flare-up. 61
28757738 2016
25
Novel PAX3-NCOA1 Fusions in Biphenotypic Sinonasal Sarcoma With Focal Rhabdomyoblastic Differentiation. 61
26371783 2016
26
A rare case of recurrent malignant triton tumor in a male with NF1: Case report and mini-review. 61
26975033 2016
27
Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. 61
26788168 2015
28
Primary epididymis malignant triton tumor: case report and review of the literature. 61
26392076 2015
29
Malignant Peripheral Nerve Sheath Tumor With Rhabdomyosarcomatous and Glandular Elements: Rare Epithelial Differentiation in a Triton Tumor. 61
25911565 2015
30
Unusual histological variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. 61
25879014 2015
31
Malignant triton tumor of the cervical spine: report of one case and review of the literature. 61
23597523 2015
32
Intracranial malignant triton tumor in a patient with neurofibromatosis type 1: case report and review of the literature. 61
23633163 2014
33
Malignant triton tumor of the anterior mediastinum: A case report. 61
24527089 2014
34
Low-grade malignant triton tumor of the neck: a case report and review of the literature. 61
25328740 2014
35
Malignant Triton Tumor of the Sciatic Nerve as a Secondary Malignancy after Extended Field Radiotherapy and Chemotherapy of Hodgkin's Disease. 61
24803902 2014
36
Optimal surgical treatment and urological outcomes in boys with pelvic and urogenital rhabdomyosarcomas and soft tissue sarcomas. 61
23989524 2013
37
A case of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation: malignant triton tumor. 61
24474920 2013
38
Malignant triton tumor of the chest wall invading the lung. A case report and literature review. 61
24470743 2013
39
Malignant triton tumor: a rare case. 61
24426617 2013
40
Oncologic manifestations in children with neurofibromatosis type 1 in Turkey. 61
24217072 2013
41
A rare case of retroperitoneal malignant Triton tumor invading renal vein and small intestine. 61
23607247 2013
42
Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management. 61
24133387 2013
43
Clinico-genetic aspects of a pediatric non-neurofibromatosis type 1 malignant triton tumor with loss of chromosome X. 61
22610852 2012
44
A-Z of malignant peripheral nerve sheath tumors. 61
23108260 2012
45
Treatment of malignant triton tumor in zygomatic region. 61
22627455 2012
46
Malignant triton tumor of the retroperitoneum: a case report and review of the literature. 61
22647059 2012
47
A rare case of malignant triton tumor in the cerebellopontine angle. 61
22515616 2012
48
Low-grade malignant triton tumor in the lumbar spine: a rare variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. 61
21732991 2012
49
Long-term survival of a patient with a neurofibromatosis Type 1 associated retroperitoneal malignant triton tumor after multi-modality treatment. 61
22011741 2011
50
[A case report of malignant triton tumor in the right parapharyngeal space]. 61
21924110 2011

Variations for Malignant Triton Tumor

Expression for Malignant Triton Tumor

Search GEO for disease gene expression data for Malignant Triton Tumor.

Pathways for Malignant Triton Tumor

Pathways related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.78 MYOG MYOD1 DES

GO Terms for Malignant Triton Tumor

Cellular components related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.8 TLE1 MYOG MYOD1

Biological processes related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to estradiol stimulus GO:0071392 9.48 MYOG MYOD1
2 positive regulation of muscle cell differentiation GO:0051149 9.46 MYOG MYOD1
3 skeletal muscle fiber development GO:0048741 9.43 MYOG MYOD1
4 positive regulation of myoblast differentiation GO:0045663 9.4 MYOG MYOD1
5 positive regulation of myoblast fusion GO:1901741 9.37 MYOG MYOD1
6 myoblast differentiation GO:0045445 9.32 MYOG MYOD1
7 myotube differentiation GO:0014902 9.26 MYOG MYOD1
8 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOG MYOD1
9 muscle cell fate commitment GO:0042693 8.96 MYOG MYOD1
10 skeletal muscle tissue development GO:0007519 8.8 NF1 MYOG MYOD1

Sources for Malignant Triton Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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