MTT
MCID: MLG041
MIFTS: 33

Malignant Triton Tumor (MTT)

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Malignant Triton Tumor

MalaCards integrated aliases for Malignant Triton Tumor:

Name: Malignant Triton Tumor 12 58 15
Malignant Peripheral Nerve Sheath Tumor with Rhabdomyosarcomatous Differenciation 58
Malignant Peripheral Nerve Sheath Tumor with Rhabdomyoblastic Differentiation 71
Malignant Peripheral Nerve Sheath Neoplasm with Rhabdomyosarcoma 12
Mpnst with Rhabdomyosarcomatous Differentiation 58
Mpnst with Rhabdomyoblastic Differentiation 12
Mpnst with Rhabdomyosarcoma 12
Malignant Triton Tumour 12
Mtt 58

Characteristics:

Orphanet epidemiological data:

58
malignant triton tumor
Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:6707
NCIt 49 C4335
SNOMED-CT 67 354002
UMLS via Orphanet 72 C0334616
Orphanet 58 ORPHA252212
UMLS 71 C0334616

Summaries for Malignant Triton Tumor

MalaCards based summary : Malignant Triton Tumor, also known as malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differenciation, is related to malignant peripheral nerve sheath tumor and neurilemmoma. An important gene associated with Malignant Triton Tumor is MB (Myoglobin), and among its related pathways/superpathways are Myogenesis and Notch-mediated HES/HEY network. Affiliated tissues include breast, bone and pituitary, and related phenotype is muscle.

Wikipedia : 74 Malignant triton tumor (MTT) is a relatively rare, aggressive tumor made up of both malignant schwannoma... more...

Related Diseases for Malignant Triton Tumor

Diseases related to Malignant Triton Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 241)
# Related Disease Score Top Affiliating Genes
1 malignant peripheral nerve sheath tumor 31.9 S100B NF1 MYOG B3GAT1
2 neurilemmoma 31.0 S100B NF1 DES
3 fibrous histiocytoma 30.5 S100B DES
4 adenosarcoma 30.3 MB DES
5 hemangiopericytoma, malignant 30.2 S100B DES
6 spindle cell sarcoma 30.1 S100B MYOG DES
7 liposarcoma 29.9 MYOG MB DES
8 histiocytoma 29.8 MYOG MYOD1 MB
9 malignant fibroxanthoma 29.8 MYOG MYOD1 DES
10 gas gangrene 29.6 MYOG MYOD1 MB
11 rhabdomyosarcoma 29.6 S100B MYOG MYOD1 MB DES
12 embryonal rhabdomyosarcoma 29.4 MYOG MYOD1 MB DES
13 botryoid rhabdomyosarcoma 29.4 MYOG MYOD1 MB DES
14 malignant mesenchymoma 29.4 MYOG MYOD1 MB DES
15 mesenchymoma 29.4 MYOG MYOD1 MB DES
16 medulloblastoma 28.8 S100B NF1 MYOG MYOD1 DES
17 sarcoma, synovial 28.5 TLE1 S100B NF1 MYOG DES
18 neurofibrosarcoma 11.4
19 neurofibromatosis, type iv, of riccardi 10.8
20 neurofibroma 10.5
21 rare tumor 10.4
22 lymphocytic leukemia 10.4
23 myofibroma 10.3 MB DES
24 pituitary tumors 10.3
25 giant cell myocarditis 10.3 MB DES
26 neurofibromatosis, type i 10.3
27 malignant giant cell tumor of soft parts 10.3 S100B MB
28 glioma 10.3
29 glial tumor 10.3
30 myxofibrosarcoma 10.3 S100B DES
31 cutaneous leiomyosarcoma 10.3 S100B DES
32 syringocystadenoma papilliferum 10.3 S100B DES
33 acute mountain sickness 10.3 S100B MB
34 bone sarcoma 10.3 MB DES
35 subleukemic leukemia 10.3 S100B MB
36 epithelioid leiomyosarcoma 10.3 MB DES
37 epithelioid malignant peripheral nerve sheath tumor 10.3 S100B NF1
38 ovarian small cell carcinoma 10.3 S100B DES
39 gastric cancer 10.2
40 acute leukemia 10.2
41 syringoma 10.2 S100B DES
42 optic nerve glioma 10.2 S100B NF1
43 inflammatory leiomyosarcoma 10.2 MYOG DES
44 cervical polyp 10.2 MYOG DES
45 pleomorphic liposarcoma 10.2 S100B DES
46 ectomesenchymoma 10.2 MYOG DES
47 perivascular epithelioid cell tumor 10.2 S100B DES
48 olfactory neuroblastoma 10.2 S100B MB
49 ovarian cancer 10.2
50 leukemia, acute lymphoblastic 10.2

Graphical network of the top 20 diseases related to Malignant Triton Tumor:



Diseases related to Malignant Triton Tumor

Symptoms & Phenotypes for Malignant Triton Tumor

MGI Mouse Phenotypes related to Malignant Triton Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.02 DES MB MYOD1 MYOG NF1

Drugs & Therapeutics for Malignant Triton Tumor

Search Clinical Trials , NIH Clinical Center for Malignant Triton Tumor

Genetic Tests for Malignant Triton Tumor

Anatomical Context for Malignant Triton Tumor

MalaCards organs/tissues related to Malignant Triton Tumor:

40
Breast, Bone, Pituitary, Lung, Thyroid, Kidney, Heart

Publications for Malignant Triton Tumor

Articles related to Malignant Triton Tumor:

(show top 50) (show all 119)
# Title Authors PMID Year
1
Triton tumor of the orbit. 61
31746248 2019
2
Malignant Triton Tumor Diagnosed on Fine Needle Aspiration Cytology. 61
31741582 2019
3
A series of 10 malignant triton tumors in one institution. 61
31490366 2019
4
Malignant triton tumor of the left thoracic cavity: a case report. 61
31528328 2019
5
Malignant triton tumor diagnosed twelve years after radiosurgically treated vestibular schwannoma. 61
31176932 2019
6
Worsening hemoptysis in a rare intrapulmonary triton tumor mimicking lung cancer. 61
31400331 2019
7
Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor. 61
28924675 2019
8
Expert's comment concerning Grand Rounds case entitled "Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor" by S. Ghailane et al. (Eur Spine J; 2017: DOI 10.1007/s00586-017-5277-2). 61
29671111 2019
9
Teaching NeuroImages: Intracranial malignant triton tumor: An uncommon location of a rare tumor. 61
30886081 2019
10
Mediastinal malignant triton tumor: A rare case series and review of literature. 61
31494456 2019
11
Malignant Triton Tumor in a Child: Case Report and Literature Review. 61
31920385 2019
12
Malignant triton tumor of the gluteal region in a patient unaffected by neurofibromatosis: A case report. 61
29110923 2018
13
Malignant triton tumor of trigeminal nerve-case report. 61
29279963 2018
14
Malignant triton tumor of the duodenum: report of a case. 61
31149515 2018
15
A rare case of intracranial malignant triton tumor arising in the middle cranial fossa: a case report and review of the literature. 61
30509044 2018
16
[A Rare Case of Abdominal Malignant Triton Tumor]. 61
29394776 2017
17
Malignant Triton Tumor (Malignant Peripheral Nerve Sheath Tumor With Rhabdomyoblastic Differentiation) Occurring in a Vascularized Free Flap Reconstruction Graft. 61
28387148 2017
18
A Case of Retroperitoneal Malignant Triton Tumor in a Nigerian Boy. 61
29089742 2017
19
Malignant Triton tumor: a rare cause of sciatic pain and foot drop. 61
28884110 2017
20
Malignant triton tumor of the lung, infiltrating the left atrium and left ventricle, with metastasis to the small intestine. 61
28515751 2017
21
Malignant Triton Tumor of the Kidney. New Location Not Previously Reported. 61
26159374 2017
22
A case of recurrent malignant triton tumor successfully treated with radiotherapy. 61
27146005 2016
23
Insidious malignant triton tumor of the chest wall with late flare-up. 61
28757738 2016
24
A rare case of recurrent malignant triton tumor in a male with NF1: Case report and mini-review. 61
26975033 2016
25
Novel PAX3-NCOA1 Fusions in Biphenotypic Sinonasal Sarcoma With Focal Rhabdomyoblastic Differentiation. 61
26371783 2016
26
Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. 61
26788168 2015
27
Primary epididymis malignant triton tumor: case report and review of the literature. 61
26392076 2015
28
Malignant Peripheral Nerve Sheath Tumor With Rhabdomyosarcomatous and Glandular Elements: Rare Epithelial Differentiation in a Triton Tumor. 61
25911565 2015
29
Unusual histological variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. 61
25879014 2015
30
Malignant triton tumor of the cervical spine: report of one case and review of the literature. 61
23597523 2015
31
Intracranial malignant triton tumor in a patient with neurofibromatosis type 1: case report and review of the literature. 61
23633163 2014
32
Malignant triton tumor of the anterior mediastinum: A case report. 61
24527089 2014
33
Low-grade malignant triton tumor of the neck: a case report and review of the literature. 61
25328740 2014
34
Malignant Triton Tumor of the Sciatic Nerve as a Secondary Malignancy after Extended Field Radiotherapy and Chemotherapy of Hodgkin's Disease. 61
24803902 2014
35
Optimal surgical treatment and urological outcomes in boys with pelvic and urogenital rhabdomyosarcomas and soft tissue sarcomas. 61
23989524 2013
36
A case of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation: malignant triton tumor. 61
24474920 2013
37
Malignant triton tumor of the chest wall invading the lung. A case report and literature review. 61
24470743 2013
38
Malignant triton tumor: a rare case. 61
24426617 2013
39
Oncologic manifestations in children with neurofibromatosis type 1 in Turkey. 61
24217072 2013
40
A rare case of retroperitoneal malignant Triton tumor invading renal vein and small intestine. 61
23607247 2013
41
Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management. 61
24133387 2013
42
Clinico-genetic aspects of a pediatric non-neurofibromatosis type 1 malignant triton tumor with loss of chromosome X. 61
22610852 2012
43
A-Z of malignant peripheral nerve sheath tumors. 61
23108260 2012
44
Treatment of malignant triton tumor in zygomatic region. 61
22627455 2012
45
Malignant triton tumor of the retroperitoneum: a case report and review of the literature. 61
22647059 2012
46
A rare case of malignant triton tumor in the cerebellopontine angle. 61
22515616 2012
47
Low-grade malignant triton tumor in the lumbar spine: a rare variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. 61
21732991 2012
48
Long-term survival of a patient with a neurofibromatosis Type 1 associated retroperitoneal malignant triton tumor after multi-modality treatment. 61
22011741 2011
49
[A case report of malignant triton tumor in the right parapharyngeal space]. 61
21924110 2011
50
Malignant triton tumor of cervical spine with hemorrhage. 61
21414786 2011

Variations for Malignant Triton Tumor

Expression for Malignant Triton Tumor

Search GEO for disease gene expression data for Malignant Triton Tumor.

Pathways for Malignant Triton Tumor

Pathways related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.72 MYOG MYOD1
2 10.3 TLE1 MYOD1

GO Terms for Malignant Triton Tumor

Cellular components related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.8 TLE1 MYOG MYOD1

Biological processes related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 skeletal muscle cell differentiation GO:0035914 9.49 MYOG MYOD1
2 cellular response to estradiol stimulus GO:0071392 9.48 MYOG MYOD1
3 positive regulation of muscle cell differentiation GO:0051149 9.46 MYOG MYOD1
4 skeletal muscle fiber development GO:0048741 9.43 MYOG MYOD1
5 positive regulation of myoblast differentiation GO:0045663 9.4 MYOG MYOD1
6 positive regulation of myoblast fusion GO:1901741 9.37 MYOG MYOD1
7 myoblast differentiation GO:0045445 9.32 MYOG MYOD1
8 myotube differentiation GO:0014902 9.26 MYOG MYOD1
9 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOG MYOD1
10 muscle cell fate commitment GO:0042693 8.96 MYOG MYOD1
11 skeletal muscle tissue development GO:0007519 8.8 NF1 MYOG MYOD1

Molecular functions related to Malignant Triton Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 E-box binding GO:0070888 8.62 MYOG MYOD1

Sources for Malignant Triton Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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