MCID: MLL004
MIFTS: 28

Mallory-Weiss Syndrome

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Mallory-Weiss Syndrome

MalaCards integrated aliases for Mallory-Weiss Syndrome:

Name: Mallory-Weiss Syndrome 53 72
Mucosal Lacerations - Gastroesophageal Junction 53
Gastroesophageal Laceration-Hemorrhage 53
Mallory-Weiss Laceration 53
Mallory-Weiss Tear 53

Classifications:



External Ids:

UMLS 72 C0024633

Summaries for Mallory-Weiss Syndrome

MalaCards based summary : Mallory-Weiss Syndrome, also known as mucosal lacerations - gastroesophageal junction, is related to hernia, hiatus and portal hypertension. The drugs Thrombin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and colon.

Wikipedia : 75 Mallory-Weiss syndrome or gastro-esophageal laceration syndrome refers to bleeding from a laceration in... more...

Related Diseases for Mallory-Weiss Syndrome

Diseases related to Mallory-Weiss Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 hernia, hiatus 10.8
2 portal hypertension 10.7
3 alcohol dependence 10.6
4 gastritis 10.6
5 boerhaave syndrome 10.6
6 varicose veins 10.5
7 duodenal ulcer 10.5
8 peptic ulcer disease 10.5
9 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.5
10 gastric ulcer 10.5
11 liver disease 10.5
12 systemic scleroderma 10.5
13 active peptic ulcer disease 10.5
14 achalasia 10.5
15 gastroesophageal reflux 10.4
16 esophageal varix 10.4
17 choledocholithiasis 10.4
18 esophagitis 10.4
19 peptic esophagitis 10.4
20 alcohol use disorder 10.4
21 gastrointestinal system disease 10.4
22 mediastinitis 10.4
23 appendicitis 10.4
24 atrophic gastritis 10.4
25 47,xyy 10.4
26 nephrolithiasis, calcium oxalate 10.3
27 diabetes mellitus, ketosis-prone 10.3
28 leptin deficiency or dysfunction 10.3
29 microinvasive gastric cancer 10.3
30 papillary carcinoma 10.3
31 pulmonary embolism 10.3
32 dysphagia 10.3
33 factor viii deficiency 10.2
34 migraine with or without aura 1 10.2
35 polyposis, gastric 10.2
36 tetralogy of fallot 10.2
37 ocular motor apraxia 10.2
38 hemophilia a 10.2
39 pallister w syndrome 10.2
40 helicobacter pylori infection 10.2
41 asthma 10.2
42 myocardial infarction 10.2
43 ischemic colitis 10.2
44 respiratory failure 10.2
45 disseminated intravascular coagulation 10.2
46 alcoholic hepatitis 10.2
47 von willebrand's disease 10.2
48 hepatic coma 10.2
49 hereditary angioedema 10.2
50 angioedema 10.2

Comorbidity relations with Mallory-Weiss Syndrome via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Deficiency Anemia Esophageal Disease
Esophagitis Heart Disease
Hypertension, Essential Paralytic Ileus

Graphical network of the top 20 diseases related to Mallory-Weiss Syndrome:



Diseases related to Mallory-Weiss Syndrome

Symptoms & Phenotypes for Mallory-Weiss Syndrome

Drugs & Therapeutics for Mallory-Weiss Syndrome

Drugs for Mallory-Weiss Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Thrombin Approved, Investigational Phase 4
2
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
3
Acenocoumarol Approved, Investigational Phase 4 152-72-7 9052 54676537
4
Phylloquinone Approved, Investigational Phase 4 84-80-0
5
Warfarin Approved Phase 4 81-81-2 6691 54678486
6
Dalteparin Approved Phase 4 9005-49-6
7 Bemiparin Approved, Investigational Phase 4 91449-79-5
8
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
9 Menaquinone Investigational Phase 4 1182-68-9
10 Fibrinolytic Agents Phase 4
11 naphthoquinone Phase 4
12 Heparin, Low-Molecular-Weight Phase 4
13 Vitamin K Phase 4
14 Anticoagulants Phase 4
15 calcium heparin Phase 4
16
Pantoprazole Approved 102625-70-7 4679
17
Epinephrine Approved, Vet_approved 51-43-4 5816
18
Racepinephrine Approved 329-65-7 838
19 Gastrointestinal Agents
20 Antacids
21 Proton Pump Inhibitors
22 Anti-Ulcer Agents
23 Sympathomimetics
24 Adrenergic alpha-Agonists
25 Adrenergic Agonists
26 Respiratory System Agents
27 Adrenergic beta-Agonists
28 Hormones
29 Epinephryl borate
30 Peripheral Nervous System Agents
31 Mydriatics
32 Neurotransmitter Agents
33 Adrenocorticotropic Hormone
34 Adrenergic Agents
35 Hormone Antagonists
36 Anti-Asthmatic Agents
37 Melanocyte-Stimulating Hormones
38 Vasoconstrictor Agents
39 beta-endorphin
40 Autonomic Agents
41 Bronchodilator Agents
42 Endorphins
43 Hormones, Hormone Substitutes, and Hormone Antagonists

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Controlled Trial to Compare Treatment With Oral Anticoagulation With Antagonists of vitaminK vs Low Molecular Weight Heparin(Bemiparin) in Patients With Anticoagulation Criteria and an Episode of Gastrointestinal Bleeding. Completed NCT01727453 Phase 4 warfarin;Bemiparina
2 Effect of Intermittent Versus Continuous Intravenous Pantoprazole for Prevention of Bleeding After Endoscopic Therapy of Bleeding Peptic Ulcers Recruiting NCT03814421 intermittent (40mg as a bolus injection daily for 72hours)
3 Over-the-scope Clips and Standard Treatments in Endoscopic Control of of Acute Bleeding From Non-variceal Upper GI Causes(OTSC Study) Recruiting NCT03216395 Epinephrine

Search NIH Clinical Center for Mallory-Weiss Syndrome

Genetic Tests for Mallory-Weiss Syndrome

Anatomical Context for Mallory-Weiss Syndrome

MalaCards organs/tissues related to Mallory-Weiss Syndrome:

41
Liver, Heart, Colon, Lung, Thyroid, T Cells

Publications for Mallory-Weiss Syndrome

Articles related to Mallory-Weiss Syndrome:

(show top 50) (show all 452)
# Title Authors PMID Year
1
[Treatment of nonvariceal upper gastrointestinal bleeding: endoluminal-endovascular-surgical]. 38
31392464 2019
2
Acquired Hemophilia A with Gastrointestinal Bleeding. 38
31280527 2019
3
The prediction value of scoring systems in Mallory-Weiss syndrome patients. 38
31145291 2019
4
Haematemesis and acute dysphagia: oesophagogastroduodenoscopy or CT-which one first? 38
31205649 2019
5
Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report. 38
30544378 2018
6
Evaluation and management of Non-variceal upper gastrointestinal bleeding. 38
29525375 2018
7
Overview of Mallory-Weiss syndrome. 38
29747789 2018
8
Mallory-Weiss syndrome diagnosed after tracheal extubation. 38
29332152 2018
9
CTA As an Adjuvant Tool for Acute Intra-abdominal or Gastrointestinal Bleeding. 38
29224657 2017
10
Imaging of the oesophagus: beyond cancer. 38
28303554 2017
11
Mallory Weiss syndrome is not associated with hiatal hernia: a matched case-control study. 38
28007004 2017
12
Application of novel endoloops to close the defects resulted from endoscopic full-thickness resection with single-channel gastroscope: a multicenter study. 38
27351654 2017
13
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification. 38
27624697 2016
14
Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania. 38
27125439 2016
15
Malory-Weis syndrome based on own experience - diagnostics and modern principles of management. 38
27213253 2016
16
The role of etiopathogenetic aspects in prediction and prevention of discontinuous-hemorrhagic (Mallory-Weiss) syndrome. 38
26998186 2016
17
Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis. 38
26755890 2016
18
Ileal Intussusception Due to Metastasis from Squamous Cell Carcinoma of the Lung Resected 12 Years Previously. 38
26662663 2015
19
Hiccups: An Unappreciated Cause of the Mallory-Weiss Syndrome. 38
26232752 2015
20
Spontaneaous linear gastric tears in a cat. 38
25703995 2015
21
The predictive capacity of the Glasgow-Blatchford score for the risk stratification of upper gastrointestinal bleeding in an emergency department. 38
25952800 2015
22
Rare case of upper gastrointestinal bleeding in achalasia. 38
25789307 2015
23
[The role of surrogate alcoholic beverages in the development of hemorrhage in the patients presenting with Mallory-Weiss syndrome]. 38
25874314 2015
24
Management of variceal and nonvariceal upper gastrointestinal bleeding in patients with cirrhosis. 38
25177367 2014
25
Hyperemesis gravidarum: a case of starvation and altered sensorium gestosis (ASG). 38
24613734 2014
26
Safety and utility of single-session endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography for the evaluation of pancreatobiliary diseases. 38
24827632 2014
27
Mortality in high-risk patients with bleeding Mallory-Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study. 38
24495010 2014
28
Coexistent hairy cell leukaemia and hepatosplenic T-cell lymphoma: a case report. 38
24621139 2014
29
Combined use of clips and nylon snare ("tulip-bundle") as a rescue endoscopic bleeding control in a mallory-weiss syndrome. 38
25328727 2014
30
Feasibility of spiral enteroscopy in Japanese patients: study in two tertiary hospitals. 38
23808946 2013
31
Observations of Acid Reflux and Motor Function in Distal Esophagus Using Simultaneous Measurements of Intra-esophageal pH and Pressure in 8 Directions With Novel Sensor Catheter - A Feasibility Study. 38
23350046 2013
32
The etiology of upper gastrointestinal bleeding in cirrhotic patients. 38
26527909 2013
33
Non-variceal gastrointestinal bleeding in patients with liver cirrhosis: a review. 38
22661272 2012
34
The Gastro-Laryngeal Tube for interventional endoscopic biliopancreatic procedures in anesthetized patients. 38
22983834 2012
35
Intramural hematoma of the esophagus after endoscopic pinch biopsy. 38
23251891 2012
36
Wernicke's encephalopathy and anabolic steroid drug abuse. Is there any possible relation? 38
23935320 2012
37
Acute upper gastrointestinal bleeding in liver cirrhosis patients. 38
23069888 2012
38
[Selection and evaluation of endoscopic resection for submucosal tumors of the esophagogastric junction originating from muscularis propria]. 38
22990919 2012
39
Mallory-Weiss syndrome: clinical and endoscopic characteristics. 38
22560400 2012
40
Mallory-Weiss syndrome. 38
21918419 2011
41
Arteriovenous malformation and gastrointestinal bleeding in patients with the HeartMate II left ventricular assist device. 38
21530318 2011
42
Single-balloon versus double-balloon endoscopy for achieving total enteroscopy: a randomized, controlled trial. 38
21272875 2011
43
Risk factors for mortality in patients with Mallory-Weiss syndrome. 38
21661406 2011
44
[Endoscopic methods of hemostasis in treatment of Mallory-Weiss syndrome]. 38
21848248 2011
45
[A different view of acute upper gastrointestinal bleeding in liver cirrhosis patients]. 38
21250489 2010
46
[Hematemesis in Togo: findings of a 12-month study in an intensive care unit]. 38
20734610 2010
47
[Mallory-Weiss syndrome: diagnosis and treatment]. 38
19931377 2010
48
Clinical evaluation of emergency endoscopic hemostasis with bipolar forceps in non-variceal upper gastrointestinal bleeding. 38
20447213 2010
49
[Mallory-Weiss lesions]. 38
20156400 2010
50
[Upper gastrointestinal bleeding in an 81-year-old woman]. 38
19819044 2010

Variations for Mallory-Weiss Syndrome

Expression for Mallory-Weiss Syndrome

Search GEO for disease gene expression data for Mallory-Weiss Syndrome.

Pathways for Mallory-Weiss Syndrome

GO Terms for Mallory-Weiss Syndrome

Sources for Mallory-Weiss Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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