MCID: MLL004
MIFTS: 27

Mallory-Weiss Syndrome

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Mallory-Weiss Syndrome

MalaCards integrated aliases for Mallory-Weiss Syndrome:

Name: Mallory-Weiss Syndrome 52 71
Mucosal Lacerations - Gastroesophageal Junction 52
Gastroesophageal Laceration-Hemorrhage 52
Mallory-Weiss Laceration 52
Mallory-Weiss Tear 52

Classifications:



External Ids:

UMLS 71 C0024633

Summaries for Mallory-Weiss Syndrome

MalaCards based summary : Mallory-Weiss Syndrome, also known as mucosal lacerations - gastroesophageal junction, is related to hernia, hiatus and portal hypertension. The drugs Heparin and Phylloquinone have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and lung.

Wikipedia : 74 Mallory-Weiss syndrome or gastro-esophageal laceration syndrome refers to bleeding from a laceration in... more...

Related Diseases for Mallory-Weiss Syndrome

Diseases related to Mallory-Weiss Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 hernia, hiatus 10.8
2 portal hypertension 10.7
3 alcohol dependence 10.6
4 gastritis 10.6
5 boerhaave syndrome 10.6
6 varicose veins 10.6
7 duodenal ulcer 10.6
8 peptic ulcer disease 10.6
9 gastric ulcer 10.5
10 liver disease 10.5
11 systemic scleroderma 10.5
12 active peptic ulcer disease 10.5
13 achalasia 10.5
14 gastroesophageal reflux 10.4
15 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.4
16 esophageal varix 10.4
17 choledocholithiasis 10.4
18 esophagitis 10.4
19 peptic esophagitis 10.4
20 alcohol use disorder 10.4
21 gastrointestinal system disease 10.4
22 mediastinitis 10.4
23 appendicitis 10.4
24 atrophic gastritis 10.4
25 47,xyy 10.4
26 diabetes mellitus, ketosis-prone 10.3
27 leptin deficiency or dysfunction 10.3
28 microinvasive gastric cancer 10.3
29 papillary carcinoma 10.3
30 nephrolithiasis 10.3
31 pulmonary embolism 10.3
32 dysphagia 10.3
33 migraine with or without aura 1 10.3
34 polyposis, gastric 10.3
35 small cell cancer of the lung 10.3
36 tetralogy of fallot 10.3
37 lung cancer 10.3
38 ocular motor apraxia 10.3
39 hemophilia a 10.3
40 pallister w syndrome 10.3
41 helicobacter pylori infection 10.3
42 asthma 10.3
43 myocardial infarction 10.3
44 ischemic colitis 10.3
45 respiratory failure 10.3
46 disseminated intravascular coagulation 10.3
47 alcoholic hepatitis 10.3
48 von willebrand's disease 10.3
49 hepatic coma 10.3
50 hereditary angioedema 10.3

Comorbidity relations with Mallory-Weiss Syndrome via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Deficiency Anemia Esophageal Disease
Esophagitis Heart Disease
Hypertension, Essential Paralytic Ileus

Graphical network of the top 20 diseases related to Mallory-Weiss Syndrome:



Diseases related to Mallory-Weiss Syndrome

Symptoms & Phenotypes for Mallory-Weiss Syndrome

Drugs & Therapeutics for Mallory-Weiss Syndrome

Drugs for Mallory-Weiss Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
2
Phylloquinone Approved, Investigational Phase 4 84-80-0
3
Acenocoumarol Approved, Investigational Phase 4 152-72-7 9052 54676537
4
Thrombin Approved, Investigational Phase 4
5
Warfarin Approved Phase 4 81-81-2 6691 54678486
6
Tinzaparin Approved Phase 4 9041-08-1, 9005-49-6 25244225
7
Dalteparin Approved Phase 4 9005-49-6
8 Bemiparin Approved, Investigational Phase 4 91449-79-5
9
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
10 Menaquinone Investigational Phase 4 1182-68-9
11 Anticoagulants Phase 4
12 Heparin, Low-Molecular-Weight Phase 4
13 Vitamin K Phase 4
14 naphthoquinone Phase 4
15 calcium heparin Phase 4
16
Pantoprazole Approved 102625-70-7 4679
17
Epinephrine Approved, Vet_approved 51-43-4 5816
18
Racepinephrine Approved 329-65-7 838
19 Proton Pump Inhibitors
20 Respiratory System Agents
21 Adrenergic alpha-Agonists
22 Adrenergic beta-Agonists
23 Adrenergic Agents
24 Vasoconstrictor Agents
25 Epinephryl borate
26 Anti-Asthmatic Agents
27 Adrenergic Agonists
28 Sympathomimetics
29 Neurotransmitter Agents
30 Mydriatics
31 Bronchodilator Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Controlled Trial to Compare Treatment With Oral Anticoagulation With Antagonists of vitaminK vs Low Molecular Weight Heparin(Bemiparin) in Patients With Anticoagulation Criteria and an Episode of Gastrointestinal Bleeding. Completed NCT01727453 Phase 4 warfarin;Bemiparina
2 Effect of Intermittent Versus Continuous Intravenous Pantoprazole for Prevention of Bleeding After Endoscopic Therapy of Bleeding Peptic Ulcers Recruiting NCT03814421 intermittent (40mg as a bolus injection daily for 72hours)
3 Over-the-scope Clips and Standard Treatments in Endoscopic Control of of Acute Bleeding From Non-variceal Upper GI Causes(OTSC Study) Recruiting NCT03216395 Epinephrine

Search NIH Clinical Center for Mallory-Weiss Syndrome

Genetic Tests for Mallory-Weiss Syndrome

Anatomical Context for Mallory-Weiss Syndrome

MalaCards organs/tissues related to Mallory-Weiss Syndrome:

40
Liver, Heart, Lung, Colon, Thyroid, T Cells

Publications for Mallory-Weiss Syndrome

Articles related to Mallory-Weiss Syndrome:

(show top 50) (show all 456)
# Title Authors PMID Year
1
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management. 61
32109037 2020
2
Acquired Hemophilia A with Gastrointestinal Bleeding. 61
31280527 2020
3
Treatment of severe upper gastrointestinal bleeding caused by Mallory-Weiss syndrome after primary coronary intervention for acute inferior wall myocardial infarction: A case report. 61
31911925 2019
4
Intramural Esophageal Hematoma Secondary to Food Ingestion. 61
31696016 2019
5
[Treatment of nonvariceal upper gastrointestinal bleeding: endoluminal-endovascular-surgical]. 61
31392464 2019
6
The prediction value of scoring systems in Mallory-Weiss syndrome patients. 61
31145291 2019
7
Haematemesis and acute dysphagia: oesophagogastroduodenoscopy or CT-which one first? 61
31205649 2019
8
Small-cell lung cancer with Mallory-Weiss syndrome as the prominent manifestation. 61
31934109 2019
9
Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report. 61
30544378 2018
10
Evaluation and management of Non-variceal upper gastrointestinal bleeding. 61
29525375 2018
11
Overview of Mallory-Weiss syndrome. 61
29747789 2018
12
Mallory-Weiss syndrome diagnosed after tracheal extubation. 61
29332152 2018
13
CTA As an Adjuvant Tool for Acute Intra-abdominal or Gastrointestinal Bleeding. 61
29224657 2017
14
Imaging of the oesophagus: beyond cancer. 61
28303554 2017
15
Mallory Weiss syndrome is not associated with hiatal hernia: a matched case-control study. 61
28007004 2017
16
Application of novel endoloops to close the defects resulted from endoscopic full-thickness resection with single-channel gastroscope: a multicenter study. 61
27351654 2017
17
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification. 61
27624697 2016
18
Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania. 61
27125439 2016
19
Malory-Weis syndrome based on own experience - diagnostics and modern principles of management. 61
27213253 2016
20
The role of etiopathogenetic aspects in prediction and prevention of discontinuous-hemorrhagic (Mallory-Weiss) syndrome. 61
26998186 2016
21
Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis. 61
26755890 2016
22
Ileal Intussusception Due to Metastasis from Squamous Cell Carcinoma of the Lung Resected 12 Years Previously. 61
26662663 2015
23
Hiccups: An Unappreciated Cause of the Mallory-Weiss Syndrome. 61
26232752 2015
24
Spontaneaous linear gastric tears in a cat. 61
25703995 2015
25
The predictive capacity of the Glasgow-Blatchford score for the risk stratification of upper gastrointestinal bleeding in an emergency department. 61
25952800 2015
26
Rare case of upper gastrointestinal bleeding in achalasia. 61
25789307 2015
27
[The role of surrogate alcoholic beverages in the development of hemorrhage in the patients presenting with Mallory-Weiss syndrome]. 61
25874314 2015
28
Management of variceal and nonvariceal upper gastrointestinal bleeding in patients with cirrhosis. 61
25177367 2014
29
Hyperemesis gravidarum: a case of starvation and altered sensorium gestosis (ASG). 61
24613734 2014
30
Safety and utility of single-session endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography for the evaluation of pancreatobiliary diseases. 61
24827632 2014
31
Mortality in high-risk patients with bleeding Mallory-Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study. 61
24495010 2014
32
Coexistent hairy cell leukaemia and hepatosplenic T-cell lymphoma: a case report. 61
24621139 2014
33
Combined use of clips and nylon snare ("tulip-bundle") as a rescue endoscopic bleeding control in a mallory-weiss syndrome. 61
25328727 2014
34
Feasibility of spiral enteroscopy in Japanese patients: study in two tertiary hospitals. 61
23808946 2013
35
Observations of Acid Reflux and Motor Function in Distal Esophagus Using Simultaneous Measurements of Intra-esophageal pH and Pressure in 8 Directions With Novel Sensor Catheter - A Feasibility Study. 61
23350046 2013
36
The etiology of upper gastrointestinal bleeding in cirrhotic patients. 61
26527909 2013
37
Non-variceal gastrointestinal bleeding in patients with liver cirrhosis: a review. 61
22661272 2012
38
The Gastro-Laryngeal Tube for interventional endoscopic biliopancreatic procedures in anesthetized patients. 61
22983834 2012
39
Intramural hematoma of the esophagus after endoscopic pinch biopsy. 61
23251891 2012
40
Wernicke's encephalopathy and anabolic steroid drug abuse. Is there any possible relation? 61
23935320 2012
41
Acute upper gastrointestinal bleeding in liver cirrhosis patients. 61
23069888 2012
42
[Selection and evaluation of endoscopic resection for submucosal tumors of the esophagogastric junction originating from muscularis propria]. 61
22990919 2012
43
Mallory-Weiss syndrome: clinical and endoscopic characteristics. 61
22560400 2012
44
Mallory-Weiss syndrome. 61
21918419 2011
45
Arteriovenous malformation and gastrointestinal bleeding in patients with the HeartMate II left ventricular assist device. 61
21530318 2011
46
Single-balloon versus double-balloon endoscopy for achieving total enteroscopy: a randomized, controlled trial. 61
21272875 2011
47
Risk factors for mortality in patients with Mallory-Weiss syndrome. 61
21661406 2011
48
[Endoscopic methods of hemostasis in treatment of Mallory-Weiss syndrome]. 61
21848248 2011
49
[A different view of acute upper gastrointestinal bleeding in liver cirrhosis patients]. 61
21250489 2010
50
[Hematemesis in Togo: findings of a 12-month study in an intensive care unit]. 61
20734610 2010

Variations for Mallory-Weiss Syndrome

Expression for Mallory-Weiss Syndrome

Search GEO for disease gene expression data for Mallory-Weiss Syndrome.

Pathways for Mallory-Weiss Syndrome

GO Terms for Mallory-Weiss Syndrome

Sources for Mallory-Weiss Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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