MCID: MLL004
MIFTS: 24

Mallory-Weiss Syndrome

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Mallory-Weiss Syndrome

MalaCards integrated aliases for Mallory-Weiss Syndrome:

Name: Mallory-Weiss Syndrome 54 74
Mucosal Lacerations - Gastroesophageal Junction 54
Gastroesophageal Laceration-Hemorrhage 54
Mallory-Weiss Laceration 54
Mallory-Weiss Tear 54

Classifications:



External Ids:

UMLS 74 C0024633

Summaries for Mallory-Weiss Syndrome

MalaCards based summary : Mallory-Weiss Syndrome, also known as mucosal lacerations - gastroesophageal junction, is related to liver disease and portal hypertension. The drugs Ondansetron and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include liver and thyroid.

Wikipedia : 77 Mallory–Weiss syndrome or gastro-esophageal laceration syndrome refers to bleeding from a laceration in... more...

Related Diseases for Mallory-Weiss Syndrome

Diseases related to Mallory-Weiss Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)
# Related Disease Score Top Affiliating Genes
1 liver disease 10.5
2 portal hypertension 10.5
3 achalasia 10.5
4 hernia, hiatus 10.4
5 peptic ulcer disease 10.4
6 boerhaave syndrome 10.4
7 diabetes mellitus, ketosis-prone 10.3
8 gastric ulcer 10.3
9 disseminated intravascular coagulation 10.3
10 factor viii deficiency 10.2
11 polyposis, gastric 10.2
12 hemophilia a 10.2
13 myocardial infarction 10.2
14 systemic scleroderma 10.2
15 esophagitis 10.2
16 von willebrand's disease 10.2
17 hepatic coma 10.2
18 peptic esophagitis 10.2
19 hereditary angioedema 10.2
20 angioedema 10.2
21 thyroid cancer 10.2
22 active peptic ulcer disease 10.2
23 appendicitis 10.2
24 intracranial hypertension 10.2
25 fatty liver disease 10.2
26 hemophilia 10.2

Comorbidity relations with Mallory-Weiss Syndrome via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Chronic Kidney Failure Deficiency Anemia
Esophageal Disease Esophagitis
Heart Disease Hypertension, Essential
Paralytic Ileus

Graphical network of the top 20 diseases related to Mallory-Weiss Syndrome:



Diseases related to Mallory-Weiss Syndrome

Symptoms & Phenotypes for Mallory-Weiss Syndrome

Drugs & Therapeutics for Mallory-Weiss Syndrome

Drugs for Mallory-Weiss Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ondansetron Approved Phase 4 99614-02-5 4595
2
Dopamine Approved Phase 4 62-31-7, 51-61-6 681
3
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
4 Psychotropic Drugs Phase 4
5 Autonomic Agents Phase 4
6 Serotonin Antagonists Phase 4
7 Dopamine Antagonists Phase 4
8 Antiemetics Phase 4
9 Central Nervous System Depressants Phase 4
10 Dermatologic Agents Phase 4
11 Serotonin Agents Phase 4
12 Neurotransmitter Agents Phase 4
13 Dopamine D2 Receptor Antagonists Phase 4
14 Gastrointestinal Agents Phase 4
15 Tranquilizing Agents Phase 4
16 Anti-Anxiety Agents Phase 4
17 Antipruritics Phase 4
18 Dopamine Agents Phase 4
19 Peripheral Nervous System Agents Phase 4
20 Antipsychotic Agents Phase 4
21
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Uncomplicated Nausea and Vomiting in the Emergency Department Completed NCT00778011 Phase 4 Ondansetron;Ondansetron;Metoclopramide
2 A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand Recruiting NCT03302858 Phase 2

Search NIH Clinical Center for Mallory-Weiss Syndrome

Genetic Tests for Mallory-Weiss Syndrome

Anatomical Context for Mallory-Weiss Syndrome

MalaCards organs/tissues related to Mallory-Weiss Syndrome:

42
Liver, Thyroid

Publications for Mallory-Weiss Syndrome

Articles related to Mallory-Weiss Syndrome:

(show top 50) (show all 163)
# Title Authors Year
1
Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report. ( 30544378 )
2018
2
Mallory-Weiss syndrome diagnosed after tracheal extubation. ( 29332152 )
2018
3
Overview of Mallory-Weiss syndrome. ( 29747789 )
2018
4
Mallory Weiss syndrome is not associated with hiatal hernia: a matched case-control study. ( 28007004 )
2017
5
Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis. ( 26755890 )
2016
6
The role of etiopathogenetic aspects in prediction and prevention of discontinuous-hemorrhagic (Mallory-Weiss) syndrome. ( 26998186 )
2016
7
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification. ( 27624697 )
2016
8
Hiccups: An Unappreciated Cause of the Mallory-Weiss Syndrome. ( 26232752 )
2015
9
Mortality in high-risk patients with bleeding Mallory-Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study. ( 24495010 )
2014
10
Combined use of clips and nylon snare ("tulip-bundle") as a rescue endoscopic bleeding control in a mallory-weiss syndrome. ( 25328727 )
2014
11
Mallory-Weiss syndrome: clinical and endoscopic characteristics. ( 22560400 )
2012
12
Risk factors for mortality in patients with Mallory-Weiss syndrome. ( 21661406 )
2011
13
Mallory-Weiss syndrome. ( 21918419 )
2011
14
Endoscopic band ligation could decrease recurrent bleeding in Mallory-Weiss syndrome as compared to haemostasis by hemoclips plus epinephrine. ( 19485979 )
2009
15
Endoscopic band ligation and endoscopic hemoclip placement for patients with Mallory-Weiss syndrome and active bleeding. ( 18395910 )
2008
16
Successful management of Mallory-Weiss syndrome in a haemophilia A patient with inhibitor by recombinant activated factor VII. ( 18445015 )
2008
17
Endoscopic band ligation therapy for upper gastrointestinal bleeding related to Mallory-Weiss syndrome. ( 16703428 )
2006
18
Intra-abdominal hemorrhage due to vigorous vomiting masked by the coexistence of Mallory-Weiss syndrome. ( 16938610 )
2006
19
Treatment of actively bleeding Mallory-Weiss syndrome: epinephrine injection or band ligation? ( 15913474 )
2005
20
Predictive factors of recurrent bleeding in Mallory-Weiss syndrome. ( 16371719 )
2005
21
A prospective, randomized trial of endoscopic band ligation vs. epinephrine injection for actively bleeding Mallory-Weiss syndrome. ( 15229420 )
2004
22
Mallory-Weiss syndrome secondary to vomiting caused by wheat-induced anaphylaxis. ( 15550156 )
2004
23
A case of Mallory-Weiss syndrome complicating pregnancy in a patient with scleroderma. ( 14717233 )
2003
24
Endoscopic hemoclip placement and epinephrine injection for Mallory-Weiss syndrome with active bleeding. ( 12024138 )
2002
25
Evaluation of endoscopic hemostasis in upper gastrointestinal bleeding related to Mallory-Weiss syndrome. ( 12048631 )
2002
26
Esophageal intramural pseudodiverticulosis with Mallory-Weiss syndrome: report of a case. ( 12107778 )
2002
27
Successful endoscopic haemoclipping in Mallory-Weiss syndrome with concurrent closure of oesophageal perforation: further prospective evaluation of the technique is required. ( 12190105 )
2002
28
Endoscopic hemoclipping for upper GI bleeding due to Mallory-Weiss syndrome. ( 11275881 )
2001
29
Endoscopic injection therapy in bleeding Mallory-Weiss syndrome: a randomized controlled trial. ( 11726841 )
2001
30
Mallory-Weiss syndrome: possible link to water immersion and subsequent air flight. ( 11090026 )
2000
31
Mallory-Weiss syndrome with severe bleeding: treatment by endoscopic ligation. ( 11103735 )
2000
32
Mallory-Weiss syndrome: clinical features and management. ( 10778523 )
1999
33
Mallory-Weiss syndrome in children. ( 10941865 )
1999
34
Gastro-esophageal barotrauma in diving: similarities with Mallory-Weiss syndrome. ( 12448028 )
1999
35
Clinical and endoscopic risk factors in the Mallory-Weiss syndrome. ( 9149189 )
1997
36
Mallory-Weiss syndrome caused by iodine-131 therapy for metastatic thyroid carcinoma. ( 9374366 )
1997
37
Mallory-Weiss syndrome in a patient with hemophilia A and chronic liver disease. ( 7579595 )
1995
38
Endoscopic sclerotherapy for upper gastrointestinal bleeding due to Mallory-Weiss syndrome. ( 7503902 )
1995
39
Mallory-Weiss syndrome complicating pregnancy in a patient with scleroderma: diagnosis and management. ( 7632647 )
1995
40
Endoscopic sclerotherapy in upper gastrointestinal bleeding due to the Mallory-Weiss syndrome. ( 7977231 )
1994
41
The influence of liver disease and portal hypertension on bleeding in Mallory-Weiss syndrome. ( 8113576 )
1994
42
The current role of endoscopy in Mallory-Weiss syndrome. ( 1678553 )
1991
43
Frequency, significance and therapy of the Mallory-Weiss syndrome in patients with portal hypertension. ( 2029986 )
1991
44
Mallory-Weiss syndrome after cardiopulmonary resuscitation. ( 2230001 )
1990
45
Frequency, significance and therapy of the Mallory-Weiss syndrome in patients with portal hypertension. ( 2347558 )
1990
46
The association of esophageal hiatus hernia with Mallory-Weiss syndrome. ( 2744343 )
1989
47
Lithium-associated Mallory-Weiss syndrome. ( 3139643 )
1988
48
Mallory-Weiss syndrome associated with raised intracranial pressure. ( 3226521 )
1988
49
Snore-induced Mallory-Weiss syndrome. ( 3559121 )
1987
50
The Mallory Weiss syndrome. A cause of sudden unexpected death due to massive haematemesis without antecedent vomiting. ( 3570703 )
1987

Variations for Mallory-Weiss Syndrome

Expression for Mallory-Weiss Syndrome

Search GEO for disease gene expression data for Mallory-Weiss Syndrome.

Pathways for Mallory-Weiss Syndrome

GO Terms for Mallory-Weiss Syndrome

Sources for Mallory-Weiss Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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