MCID: MLT013
MIFTS: 22

Malt Worker's Lung

Categories: Immune diseases, Respiratory diseases

Aliases & Classifications for Malt Worker's Lung

MalaCards integrated aliases for Malt Worker's Lung:

Name: Malt Worker's Lung 12 15
Malt-Workers' Lung 12 71
Alveolitis Due to Aspergillus Clavatus 12
Malt Workers' Lung 12
Malt Worker Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2314
ICD9CM 34 495.4
SNOMED-CT 67 25897000
ICD10 32 J67.4
UMLS 71 C0155888

Summaries for Malt Worker's Lung

Disease Ontology : 12 An extrinsic allergic alveolitis which is caused by inhalation of fungal spores of Aspergillus clavatus and Aspergillus fumigatus from moldy barley.

MalaCards based summary : Malt Worker's Lung, also known as malt-workers' lung, is related to fumarate hydratase deficiency and macular degeneration, age-related, 14. An important gene associated with Malt Worker's Lung is SCAP (SREBF Chaperone), and among its related pathways/superpathways are HIF-1-alpha transcription factor network and Development_Leptin signaling via JAK/STAT and MAPK cascades. Affiliated tissues include lung and pituitary, and related phenotypes are cellular and growth/size/body region

Related Diseases for Malt Worker's Lung

Diseases related to Malt Worker's Lung via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 fumarate hydratase deficiency 9.7 HIF1A FOS
2 macular degeneration, age-related, 14 9.6 FOS ATG5
3 ocular hypertension 9.5 MYOC FOS
4 disease of mental health 8.5 TOR1A TBL1X SETD1A HIF1A FOS ATG5

Symptoms & Phenotypes for Malt Worker's Lung

MGI Mouse Phenotypes related to Malt Worker's Lung:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.7 ATG5 FOS HIF1A NPR1 RASD1 SETD1A
2 growth/size/body region MP:0005378 9.56 ATG5 FOS HIF1A NPR1 RASD1 SCAP
3 homeostasis/metabolism MP:0005376 9.23 ATG5 FOS HIF1A NPR1 RASD1 SCAP

Drugs & Therapeutics for Malt Worker's Lung

Search Clinical Trials , NIH Clinical Center for Malt Worker's Lung

Genetic Tests for Malt Worker's Lung

Anatomical Context for Malt Worker's Lung

MalaCards organs/tissues related to Malt Worker's Lung:

40
Lung, Pituitary

Publications for Malt Worker's Lung

Articles related to Malt Worker's Lung:

# Title Authors PMID Year
1
Occupational hypersensitivity pneumonitis reported to the Czech National Registry Of Occupational Diseases in the period 1992-2005. 61
19672020 2009
2
Interstitial pneumonitis induced in guinea pigs by the antigens of Rhizopus nigricans. 61
9161935 1997
3
[Exogenous allergic alveolitis: 22 year follow-up of malt worker's lung]. 61
7892155 1995
4
[Diagnostic aspects of allergic alveolitis]. 61
2099011 1990
5
[Pituitary gland extract insufflation lung]. 61
7102010 1982

Variations for Malt Worker's Lung

Expression for Malt Worker's Lung

Search GEO for disease gene expression data for Malt Worker's Lung.

Pathways for Malt Worker's Lung

Pathways related to Malt Worker's Lung according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.77 HIF1A FOS
2
Show member pathways
10.1 HIF1A FOS

GO Terms for Malt Worker's Lung

Biological processes related to Malt Worker's Lung according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 8.96 HIF1A FOS
2 negative regulation of reactive oxygen species metabolic process GO:2000378 8.62 HIF1A ATG5

Molecular functions related to Malt Worker's Lung according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor binding GO:0008134 8.92 TBL1X SETD1A HIF1A FOS

Sources for Malt Worker's Lung

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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