Mammary Analogue Secretory Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MMM007 MIFTS: 34	Mammary Analogue Secretory Carcinoma Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Oral diseases
Genes Tissues Related diseases Publications Pathways Expand all tables

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Aliases & Classifications for Mammary Analogue Secretory Carcinoma

MalaCards integrated aliases for Mammary Analogue Secretory Carcinoma:

Name: Mammary Analogue Secretory Carcinoma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Oral diseases Gastrointestinal diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0080808

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Summaries for Mammary Analogue Secretory Carcinoma

Disease Ontology : ¹² A salivary gland carcinoma that has material basis in a chromosomal translocation that results in an ETV6-NTRK3 fusion gene.

MalaCards based summary : Mammary Analogue Secretory Carcinoma is related to acinar cell carcinoma and pleomorphic adenoma. An important gene associated with Mammary Analogue Secretory Carcinoma is ETV6 (ETS Variant Transcription Factor 6), and among its related pathways/superpathways are ERK Signaling and Toll-like Receptor Signaling Pathway. Affiliated tissues include salivary gland, breast and thyroid, and related phenotypes are endocrine/exocrine gland and digestive/alimentary

Wikipedia : ⁷⁴ Mammary analogue secretory carcinoma (MASC) (also termed MASCSG; the "SG" subscript indicates salivary... more...

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Related Diseases for Mammary Analogue Secretory Carcinoma

Diseases related to Mammary Analogue Secretory Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 240)

#	Related Disease	Score	Top Affiliating Genes
1	acinar cell carcinoma	31.3	TP53 NTRK3 ETV6 CTNNB1
2	pleomorphic adenoma	30.7	TP53 MUC1 CTNNB1
3	adenoma	30.4	TP53 MUC1 CTNNB1 CCND1
4	mucinous adenocarcinoma	30.4	TP53 MUC1 EGFR
5	salivary gland carcinoma	30.4	TP53 NTRK3 ETV6 EGFR
6	breast secretory carcinoma	30.3	STAT5A NTRK3 MUC4 ETV6
7	rhabdoid cancer	30.2	TP53 MUC1 CCND1
8	mucoepidermoid carcinoma	30.2	TP53 MUC4 MUC1 EGFR CTNNB1 CCND1
9	polymorphous low-grade adenocarcinoma	30.1	NTRK3 MUC1 CTNNB1 CCND1
10	lymphangioma	30.0	TP53 EGFR CTNNB1 CCND1
11	atypical teratoid rhabdoid tumor	29.9	TP53 MUC1 CTNNB1 CCND1
12	adenocarcinoma	29.7	TP53 NTRK3 MUC4 MUC1 EGFR CTNNB1
13	in situ carcinoma	29.7	TP53 MUC1 EGFR CTNNB1 CCND1
14	adenoid cystic carcinoma	29.5	TP53 SOX10 NTRK3 MUC1 EGFR CTNNB1
15	cystadenocarcinoma	10.6
16	rare tumor	10.4
17	cellular congenital mesoblastic nephroma	10.4	NTRK3 ETV6
18	adult fibrosarcoma	10.4	NTRK3 ETV6
19	breast adenoid cystic carcinoma	10.4	NTRK3 ETV6
20	cerebellar angioblastoma	10.3	NTRK3 ETV6
21	microcystic stromal tumor	10.3	CTNNB1 CCND1
22	kidney cortex disease	10.3	NTRK3 ETV6
23	malignant peritoneal mesothelioma	10.3	MUC1 EGFR
24	breast scirrhous carcinoma	10.3	MUC1 EGFR
25	polykaryocytosis inducer	10.3
26	oncocytoma	10.3
27	facial paralysis	10.3
28	appendix adenocarcinoma	10.3
29	myoepithelial carcinoma	10.3
30	epithelial-myoepithelial carcinoma	10.3
31	lymphoepithelioma-like carcinoma	10.3
32	posttransplant acute limbic encephalitis	10.3
33	rapidly involuting congenital hemangioma	10.3
34	ethmoid sinus adenocarcinoma	10.2	EGFR CCND1
35	chronic ethmoiditis	10.2	MUC4 MUC1
36	esophageal leukoplakia	10.2	TP53 CCND1
37	bile duct mucoepidermoid carcinoma	10.2	MUC4 MUC1
38	lung sarcomatoid carcinoma	10.2	MUC4 MUC1
39	pediatric fibrosarcoma	10.2	NTRK3 ETV6
40	pleomorphic adenoma carcinoma	10.2	TP53 NTRK3
41	filamentary keratitis	10.2	MUC4 MUC1
42	vulvar intraepithelial neoplasia	10.2	TP53 CTNNB1
43	mucinous tubular and spindle renal cell carcinoma	10.2	MUC4 MUC1
44	biliary tract cancer	10.2	MUC4 EGFR
45	limbal stem cell deficiency	10.2	MUC4 MUC1
46	nephroma	10.2	NTRK3 MUC1 ETV6
47	ischemic fasciitis	10.2	MUC1 CCND1
48	esophageal basaloid squamous cell carcinoma	10.2	TP53 EGFR
49	spindle cell sarcoma	10.2	NTRK3 MUC1 ETV6
50	frontal lobe neoplasm	10.2	TP53 EGFR

Graphical network of the top 20 diseases related to Mammary Analogue Secretory Carcinoma:

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Symptoms & Phenotypes for Mammary Analogue Secretory Carcinoma

MGI Mouse Phenotypes related to Mammary Analogue Secretory Carcinoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	10.01	CCND1 CTNNB1 EGFR ETV6 PLIN2 SOX10
2	digestive/alimentary	MP:0005381	9.98	CA6 CCND1 CTNNB1 EGFR ETV6 SOX10
3	integument	MP:0010771	9.97	CCND1 CTNNB1 EGFR ETV6 PLIN2 SOX10
4	liver/biliary system	MP:0005370	9.8	CTNNB1 EGFR ETV6 PLIN2 STAT5A TP53
5	neoplasm	MP:0002006	9.73	CCND1 CTNNB1 EGFR ETV6 SOX10 TP53
6	no phenotypic analysis	MP:0003012	9.63	CTNNB1 EGFR ETV6 NTRK3 SOX10 TP53
7	normal	MP:0002873	9.56	CCND1 CTNNB1 EGFR ETV6 NTRK3 SOX10
8	respiratory system	MP:0005388	9.1	CCND1 CTNNB1 EGFR NTRK3 SOX10 TP53

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Drugs & Therapeutics for Mammary Analogue Secretory Carcinoma

Search Clinical Trials , NIH Clinical Center for Mammary Analogue Secretory Carcinoma

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Genetic Tests for Mammary Analogue Secretory Carcinoma

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Anatomical Context for Mammary Analogue Secretory Carcinoma

MalaCards organs/tissues related to Mammary Analogue Secretory Carcinoma:

⁴⁰

Salivary Gland, Breast, Thyroid, Skin, Lymph Node, Tongue

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Publications for Mammary Analogue Secretory Carcinoma

Articles related to Mammary Analogue Secretory Carcinoma:

(show top 50) (show all 131)

#	Title	Authors	PMID	Year
1	Secretory Carcinoma (Mammary Analogue Secretory Carcinoma) of the Vulva With ETV6 Gene Rearrangement: A Brief Report With Follow-up. ⁶¹	Baban F...Schoolmeester JK	33290355	2021
2	Primary Mammary-Analogue Secretory Carcinoma of the Lung: A Rare Entity With an Unusual Location. ⁶¹	Ramos J...Gattuso P	32279588	2020
3	Concurrent Identification of Novel EGFR-SEPT14 Fusion and ETV6-RET Fusion in Secretory Carcinoma of the Salivary Gland. ⁶¹	Black M...Cotzia P	31502214	2020
4	Atypical Presentation of Mammary Analogue Secretory Carcinoma of the Lip. ⁶¹	Yassin-Kassab A...Sufyan AS	32951456	2020
5	MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics. ⁶¹	Taverna C...Agaimy A	32931030	2020
6	MR imaging findings of a rare pediatric parotid tumor: Mammary analogue secretory carcinoma. ⁶¹	Helmy D...Ozturk A	32642018	2020
7	A case of mammary analogue secretory carcinoma of the parotid gland: A case report. ⁶¹	Kim SH...Lee DJ	32664055	2020
8	Perithyroidal Salivary Gland Acinic Cell Carcinoma: Morphological and Molecular Attributes of a Unique Lesion. ⁶¹	Juhlin CC...Zedenius J	32519264	2020
9	(Mammary Analogue) Secretory Carcinoma of the Nasal Cavity: Report of a Rare Case with p63 and DOG1 Expression and Uncommon Exon 4-Exon 14 ETV6-NTRK3 Fusion Diagnosed with Next Generation Sequencing. ⁶¹	Wu B...Petersson F	31273600	2020
10	Mammary analogue secretory carcinoma: A case report. ⁶¹	Hedhli F...Khatteche B	32395809	2020
11	Mammary analogue secretory carcinoma: An Indian experience of a novel entity. ⁶¹	Nisar Z...Kadkol GA	32108646	2020
12	Outcomes of treatment of mammary analogue secretory carcinoma of the parotid gland. ⁶¹	Lee DH...Lim SC	31859109	2020
13	[Secretory carcinoma of the salivary gland (mammary analogue secretory carcinoma) in children]. ⁶¹	Sidorov IV...Konovalov DM	32307438	2020
14	Synchronous Parotid (Mammary Analog) Secretory Carcinoma and Acinic Cell Carcinoma: Report of a Case. ⁶¹	Mossinelli C...Pagella F	29876739	2019
15	Clinical characteristics of acinic cell carcinoma and secretory carcinoma of the parotid gland. ⁶¹	Terada T...Hirose Y	31440815	2019
16	Macrocystic (Mammary Analogue) Secretory Carcinoma: An Unusual Variant and a Pitfall in the Differential Diagnosis of Cystic Lesions in the Head and Neck. ⁶¹	Hernandez-Prera JC...Wenig BM	31464708	2019
17	Mammary analogue secretory carcinoma presenting as a cystic parotid mass. ⁶¹	Gupta K...Lack CM	31338135	2019
18	Immunohistochemistry with a pan-TRK antibody distinguishes secretory carcinoma of the salivary gland from acinic cell carcinoma. ⁶¹	Hung YP...Hornick JL	30801752	2019
19	Locally advanced mammary analogue secretory carcinoma of the parotid gland. ⁶¹	Tokuzen N...Nakashiro K	30777712	2019
20	Higher Ki67 Index, Nodal Involvement, and Invasive Growth Were High Risk Factors for Worse Prognosis in Conventional Mammary Analogue Secretory Carcinoma. ⁶¹	Sun J...Li J	30779892	2019
21	Diagnostic utility of fluorescence in situ hybridization testing on cytology cell blocks for the definitive classification of salivary gland neoplasms. ⁶¹	Darras N...Long SR	31097292	2019
22	Mammary analogue secretory carcinoma of salivary gland diagnosed on submandibular gland cytology: A case report and review of the literature. ⁶¹	Al-Husseinawi E...Omoscharka E	30506593	2019
23	Neurotrophic tropomyosin or tyrosine receptor kinase (NTRK) genes. ⁶¹	Chetty R	30636697	2019
24	How I treat NTRK gene fusion-positive cancers. ⁶¹	Lassen U	31803506	2019
25	Mammary analogue secretory carcinoma of the minor salivary gland: report of two cases. ⁶¹	Li Z...Zhang K	31933835	2019
26	The significance of the morphological and immunological characteristics in the diagnosis of parotid mammary analogue secretory carcinoma: five case reports and a review of the literature. ⁶¹	Cai Y...Wang Z	31934046	2019
27	A Challenging Case of Mammary Analogue Secretory Carcinoma: Case Study with Ultrastructural and Cytogenetic Correlation. ⁶¹	Mathew J...Salama S	31929931	2019
28	Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature. ⁶¹	Boliere C...Fung H	30937197	2019
29	A case report of parotid mammary analogue secretory carcinoma and reviews. ⁶¹	Sun L...Shemen L	30716709	2019
30	Mammary Analogue Secretory Carcinoma Arising in the Parotid Gland of Child. ⁶¹	Shigeta R...Hayashi A	30656126	2018
31	Molecular Profiling of Salivary Gland Intraductal Carcinoma Revealed a Subset of Tumors Harboring NCOA4-RET and Novel TRIM27-RET Fusions: A Report of 17 cases. ⁶¹	Skalova A...Michal M	30045065	2018
32	Mammary analogue secretory carcinoma of salivary glands: Report of clinical case. ⁶¹	Rovira C...Lopez M	29033125	2018
33	Mammary Analogue Secretory Carcinoma of the Thyroid Mimicking Locally Advanced Papillary Thyroid Carcinoma: A Rare Case Report. ⁶¹	Liao H...Cornejo KM	29228842	2018
34	Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma. ⁶¹	Kuwabara H...Hirose Y	30186957	2018
35	Salivary Secretory Carcinoma With a Novel ETV6-MET Fusion: Expanding the Molecular Spectrum of a Recently Described Entity. ⁶¹	Rooper LM...Kang H	29683815	2018
36	MR imaging features of mammary analogue secretory carcinoma and acinic cell carcinoma of the salivary gland: a preliminary report. ⁶¹	Kashiwagi N...Tomiyama N	29493279	2018
37	Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands. ⁶¹	Boon E...van Herpen CML	29909898	2018
38	The screening and electron microscopy observation of mammary analogue secretory carcinoma in Chinese. ⁶¹	Zhong Y...Li H	29752049	2018
39	Secretory carcinoma of the parotid with adenoid cystic carcinoma cytological pattern: A cytological-pathological correlation with literature review. ⁶¹	Kravtsov O...Giorgadze T	29566949	2018
40	Primary mammary analogue secretory carcinoma of the lung: a case report. ⁶¹	Huang T...Myers JL	29104113	2018
41	Primary cutaneous secretory carcinoma: A previously overlooked low-grade sweat gland carcinoma. ⁶¹	Llamas-Velasco M...Rutten A	29205457	2018
42	Esophageal Mammary Analogue Secretory Carcinoma. ⁶¹	Chang CY...Hou MC	28189694	2018
43	Additional diagnostic features of mammary analogue secretory carcinoma on cytology. ⁶¹	Gonzalez MF...Manucha V	28929545	2018
44	Mammary Analogue Secretory Carcinoma of Minor Salivary Glands: A Rare Case Series and Review of the Literature. ⁶¹	Roy S...Zhao B	29531003	2018
45	Special types of thyroid carcinoma. ⁶¹	Baloch ZW...LiVolsi VA	29239042	2018
46	Ultrastructural Characterization of Mammary Analogue Secretory Carcinoma of the Salivary Glands: A Distinct Entity from Acinic Cell Carcinoma? ⁶¹	Guilmette J...Sadow PM	28194567	2017
47	Pure intraductal carcinoma of the parotid gland: Cytologic findings on FNA sample. Report of one case. ⁶¹	Barizzi J...Fulciniti F	28646544	2017
48	Secretory carcinoma - impact of translocation and gene fusions on salivary gland tumor. ⁶¹	Inaki R...Hoshi K	29142456	2017
49	Mammary analogue secretory carcinoma of salivary glands: diagnostic pitfall with distinct immunohistochemical profile and molecular features. ⁶¹	Bissinger O...Mogler C	29081930	2017
50	A systematic review including an additional pediatric case report: Pediatric cases of mammary analogue secretory carcinoma. ⁶¹	Ngouajio AL...Dahl JP	28802370	2017

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Genes for Mammary Analogue Secretory Carcinoma

Genes related to Mammary Analogue Secretory Carcinoma (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ETV6	ETS Variant Transcription Factor 6	Protein Coding	8.02	GeneCards inferred via : Publications (show sections)
2	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	7.82	GeneCards inferred via : Publications (show sections)
3	CA6	Carbonic Anhydrase 6	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
4	CCND1	Cyclin D1	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
5	CTNNB1	Catenin Beta 1	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
6	EGFR	Epidermal Growth Factor Receptor	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
7	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
8	MUC4	Mucin 4, Cell Surface Associated	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
9	PLIN2	Perilipin 2	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
10	SCGB2A2	Secretoglobin Family 2A Member 2	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
11	SOX10	SRY-Box Transcription Factor 10	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
12	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
13	TP53	Tumor Protein P53	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)

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Variations for Mammary Analogue Secretory Carcinoma

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Expression for Mammary Analogue Secretory Carcinoma

Search GEO for disease gene expression data for Mammary Analogue Secretory Carcinoma.

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Pathways for Mammary Analogue Secretory Carcinoma

Pathways related to Mammary Analogue Secretory Carcinoma according to GeneCards Suite gene sharing:

(show all 31)

#	Super pathways	Score	Top Affiliating Genes
1	ERK Signaling ⁶³ Show member pathways ILK Signaling ⁶³ MAPK Signaling ⁶³ Molecular Mechanisms of Cancer ⁶³ Rho Family GTPases ⁶³	13.53	TP53 STAT5A SOX10 NTRK3 MUC1 EGFR
2	Toll-like Receptor Signaling Pathway ³⁶ ¹ Show member pathways Chagas disease ³⁶ Hepatitis B ³⁶ Hepatitis C ³⁶ Regulation of toll-like receptor signaling pathway ¹	12.89	TP53 STAT5A EGFR CTNNB1 CCND1
3	Endometrial cancer ³⁶ Show member pathways Acute myeloid leukemia ³⁶ Binding of TCF/LEF-CTNNB1 to target gene promoters ⁶⁵ Chronic myeloid leukemia ³⁶ Colorectal cancer ³⁶ Pancreatic cancer ³⁶ Prostate cancer ³⁶ Signal transduction PTEN pathway ²³ Thyroid cancer ³⁶	12.62	TP53 STAT5A EGFR CTNNB1 CCND1
4	Gastric cancer ³⁶ Show member pathways Breast cancer ³⁶ Hepatocellular carcinoma ³⁶	12.61	TP53 EGFR CTNNB1 CCND1
5	Pathways in cancer ³⁶	12.56	TP53 STAT5A EGFR CTNNB1 CCND1
6	Glioma ³⁶ Show member pathways Endocrine resistance ³⁶ Melanoma ³⁶ Non-small cell lung cancer ³⁶ Signaling Pathways in Glioblastoma ¹	12.53	TP53 STAT5A EGFR CCND1
7	ErbB signaling pathway ³⁶ ¹ Show member pathways EGFR Inhibitor Pathway, Pharmacodynamics ⁶⁰ EGFR tyrosine kinase inhibitor resistance ³⁶ Renal cell carcinoma ³⁶ TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer ¹	12.45	TP53 STAT5A EGFR CCND1
8	Development Endothelin-1/EDNRA signaling ²³ Show member pathways Cytoskeleton remodeling FAK signaling ²³ Development Endothelin-1/EDNRA transactivation of EGFR ²³ GnRH signaling pathway ³⁶ Inflammatory mediator regulation of TRP channels ³⁶	12.45	STAT5A EGFR CTNNB1 CCND1
9	Immune response IL-23 signaling pathway ²³ Show member pathways Angiopoietin receptor Tie2-mediated signaling ¹ Angiopoietin-TIE2 Signaling ⁶³ Development Angiopoietin - Tie2 signaling ²³ Development PDGF signaling via STATs and NF-kB ²³ IL23-mediated signaling events ¹ Immune response IL-10 signaling pathway ²³ Rac1/Pak1/p38/MMP-2 pathway ¹	12.42	TP53 STAT5A EGFR CTNNB1
10	VEGF Signaling ⁶⁶ Show member pathways EGFR Signaling Pathway ⁶⁶ TGF-beta Signaling Pathway ⁶⁶ VEGF Signaling Pathway ⁶⁰	12.31	TP53 MUC1 EGFR CTNNB1
11	Apoptosis Pathway ⁷⁰ Show member pathways Akt Pathway ⁷⁰ NF-kappaB Pathway ⁷⁰	12.26	TP53 NTRK3 EGFR CTNNB1
12	MAPK Signaling: Mitogen Stimulation Pathway ⁶⁴ Show member pathways Akt Signaling Pathway ⁶⁴	12.06	TP53 NTRK3 EGFR CCND1
13	Wnt signaling pathway ³⁶	12.03	TP53 CTNNB1 CCND1
14	Translation Non-genomic (rapid) action of Androgen Receptor ²³ Show member pathways Basal cell carcinoma ³⁶ Transcription Androgen Receptor nuclear signaling ²³	12.03	TP53 EGFR CTNNB1 CCND1
15	Brain-Derived Neurotrophic Factor (BDNF) signaling pathway ¹	11.98	STAT5A NTRK3 CTNNB1
16	Proteoglycans in cancer ³⁶	11.98	TP53 EGFR CTNNB1 CCND1
17	Adipogenesis ¹	11.93	STAT5A PLIN2 CTNNB1
18	Thyroid hormone signaling pathway ³⁶	11.88	TP53 CTNNB1 CCND1
19	Spinal Cord Injury ¹	11.87	TP53 EGFR CCND1
20	DNA Damage Response (only ATM dependent) ¹	11.85	TP53 CTNNB1 CCND1
21	Interleukin-4 and 13 signaling ⁶⁵	11.83	TP53 MUC1 CCND1
22	Colorectal Cancer Metastasis ⁶³	11.78	TP53 EGFR CTNNB1 CCND1
23	Androgen receptor signaling pathway ¹	11.69	EGFR CTNNB1 CCND1
24	Integrated Breast Cancer Pathway ¹	11.64	TP53 EGFR CTNNB1 CCND1
25	Bladder cancer ³⁶ ¹	11.56	TP53 EGFR CCND1
26	Central carbon metabolism in cancer ³⁶	11.53	TP53 NTRK3 EGFR
27	Association Between Physico-Chemical Features and Toxicity Associated Pathways ¹	11.5	STAT5A EGFR CTNNB1
28	Photodynamic therapy-induced AP-1 survival signaling. ¹	11.21	TP53 EGFR CCND1
29	Glioblastoma Multiforme ⁶³	10.97	TP53 EGFR CTNNB1 CCND1
30	Immune response_Oncostatin M signaling via JAK-Stat in human cells ²³	10.92	STAT5A CCND1
31	Gastric Cancer Network 2 ¹	10.65	TP53 EGFR CTNNB1

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GO Terms for Mammary Analogue Secretory Carcinoma

Biological processes related to Mammary Analogue Secretory Carcinoma according to GeneCards Suite gene sharing:

(show all 14)

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of transcription by RNA polymerase II	GO:0000122	9.91	TP53 SOX10 ETV6 CTNNB1 CCND1
2	response to drug	GO:0042493	9.67	TP53 PLIN2 CTNNB1 CCND1
3	response to organic cyclic compound	GO:0014070	9.65	PLIN2 EGFR CCND1
4	cytokine-mediated signaling pathway	GO:0019221	9.62	TP53 STAT5A MUC1 CCND1
5	response to estradiol	GO:0032355	9.61	EGFR CTNNB1 CCND1
6	positive regulation of neuroblast proliferation	GO:0002052	9.54	SOX10 CTNNB1
7	response to X-ray	GO:0010165	9.52	TP53 CCND1
8	response to corticosterone	GO:0051412	9.49	NTRK3 CCND1
9	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	GO:0006978	9.46	TP53 MUC1
10	positive regulation of production of miRNAs involved in gene silencing by miRNA	GO:1903800	9.4	TP53 EGFR
11	mitotic G1 DNA damage checkpoint	GO:0031571	9.26	TP53 CCND1
12	positive regulation of transcription from RNA polymerase II promoter in response to stress	GO:0036003	9.16	TP53 MUC1
13	cellular response to drug	GO:0035690	9.13	TP53 SOX10 EGFR
14	response to UV-A	GO:0070141	8.62	EGFR CCND1

Molecular functions related to Mammary Analogue Secretory Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chromatin binding	GO:0003682	9.67	TP53 SOX10 EGFR CTNNB1
2	enzyme binding	GO:0019899	9.62	TP53 EGFR CTNNB1 CCND1
3	transcription factor binding	GO:0008134	9.56	TP53 SOX10 CTNNB1 CCND1
4	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding	GO:0001216	9.16	TP53 SOX10
5	protein phosphatase binding	GO:0019903	9.13	TP53 EGFR CTNNB1
6	p53 binding	GO:0002039	8.8	TP53 NTRK3 MUC1

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Sources for Mammary Analogue Secretory Carcinoma

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⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

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⁶¹ PubMed

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⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

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⁷¹ UMLS

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⁷⁴ Wikipedia