MCID: MND001
MIFTS: 23

Mandibular Cancer

Categories: Bone diseases, Cancer diseases, Oral diseases

Aliases & Classifications for Mandibular Cancer

MalaCards integrated aliases for Mandibular Cancer:

Name: Mandibular Cancer 12 15 17
Mandibular Neoplasms 43 71
Malignant Neoplasm of Inferior Maxilla 12
Malignant Neoplasm of Lower Jaw Bone 12
Malignant Neoplasm of Mandible 12
Neoplasm of Mandible 12
Mandibular Neoplasm 12
Mandible Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2338
ICD9CM 34 170.1
MeSH 43 D008339
NCIt 49 C35178
ICD10 32 C41.1
UMLS 71 C0024694 C0153511

Summaries for Mandibular Cancer

Disease Ontology : 12 A jaw cancer and mandibular disease that affects your lower jawbone.

MalaCards based summary : Mandibular Cancer, also known as mandibular neoplasms, is related to mccune-albright syndrome and endometriosis. An important gene associated with Mandibular Cancer is ST7 (Suppression Of Tumorigenicity 7). The drugs Bupivacaine and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Mandibular Cancer

Diseases related to Mandibular Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mccune-albright syndrome 9.8
2 endometriosis 9.8
3 osteogenic sarcoma 9.7
4 warthin tumor 9.7
5 esophagus carcinoma in situ 9.4 ENSG00000252283 COL27A1

Graphical network of the top 20 diseases related to Mandibular Cancer:



Diseases related to Mandibular Cancer

Symptoms & Phenotypes for Mandibular Cancer

Drugs & Therapeutics for Mandibular Cancer

Drugs for Mandibular Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational 38396-39-3, 2180-92-9 2474
2 Anesthetics, Local
3 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Virtual Surgical Planning Systems and Customized Devices in Fibula Free Flap Mandibular Recontruction Completed NCT03869723
2 Inferior Alveolar Nerve Block for Intraoperative Analgesia for Maxillofacial Cancer Surgery Requiring Unilateral Mandibular Resection-A Randomized Controlled Study Completed NCT02745288
3 Assessment of Neurosensory Function Following Segmental Mandibular Resection of Non-malignant Lesions With Inferior Alveolar Nerve Preservation: A Case Series Trial Recruiting NCT03752554
4 Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using Free Fibular Flap With and Without CAD/CAM Customized Osteotomy Guide (A Randomized Controlled Clinical Trial) Recruiting NCT03757273
5 Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: An Open-Label, Prospective Pilot Clinical Study Recruiting NCT03057223

Search NIH Clinical Center for Mandibular Cancer

Cochrane evidence based reviews: mandibular neoplasms

Genetic Tests for Mandibular Cancer

Anatomical Context for Mandibular Cancer

MalaCards organs/tissues related to Mandibular Cancer:

40
Bone

Publications for Mandibular Cancer

Articles related to Mandibular Cancer:

(show all 30)
# Title Authors PMID Year
1
Cost and lack of insurance coverage are prohibitive to having dental implants after resections for benign mandibular neoplasms. 61
28169143 2017
2
[McCune-Albright syndrome with initial symtom of mandibular neoplasms: a case report]. 61
28219176 2017
3
Spontaneous Regeneration of the Mandible: An Institutional Audit of Regenerated Bone and Osteocompetent Periosteum. 61
26970145 2016
4
Bite Force and Masticatory Performance Using Implant-supported Overdentures After Treatment of Mandibular Cancer. 61
27466516 2016
5
Is a computer-assisted design and computer-assisted manufacturing method for mandibular reconstruction economically viable? 61
27193477 2016
6
Evaluation of Masticatory Efficiency and QoL Improvements After Prosthetic Rehabilitation of Mandibular Cancer Patients Reconstructed with a Fibula Free Flap. 61
26218029 2015
7
Fluorodeoxyglucose-positive Warthin tumor in a neck node mimicking metastasis in primary intraosseous left posterior mandibular cancer staging with positron emission tomography/computed tomography. 61
21549478 2011
8
Reconstruction of segmental hemi-mandibular defects using soft tissue flaps in patients with severe comorbidity and advanced head and neck cancer. 61
20571592 2008
9
Two sites of head and neck squamous cell carcinoma: utility of loss of heterozygosity. 61
18771075 2008
10
Anterior mandible canal communications: a potential portal of entry for tumour spread. 61
18316502 2008
11
The use of cone beam computed tomography as an aid in evaluating and treatment planning for mandibular cancer. 61
17368377 2007
12
Current status of transport-disc-distraction osteogenesis for mandibular reconstruction. 61
17395106 2007
13
[Treatment of mandibular neoplasms with surgery and adjunctive microwave:a preliminary report]. 61
14966650 2003
14
Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells. 61
11795887 2002
15
Segmental resection of the anterior mandibular arch with fibular microvascular reconstruction. 61
11905316 1997
16
Is nasotracheal intubation safe in surgery for mandibular cancer? 61
1627294 1992
17
Major mandibular reconstruction with vascularized bone graft. 61
1973708 1990
18
[Free vascular pedicle iliac bone graft for reconstruction of mandibular defect with ECT scan monitor]. 61
2612333 1989
19
[Radiation therapy combined with hyperthermia in advanced cancer]. 61
3094119 1986
20
[Mandibular neoplasms--hemiresection and immediate resection]. 61
1075591 1976
21
[Mandibular neoplasms metastased from cancer of the lower lip]. 61
4780565 1973
22
[Case of mandibular cancer. Clinics, diagnosis and differential diagnostics]. 61
4500337 1972
23
[Diagnosis and differential diagnosis of neural mandibular neoplasms]. 61
5002292 1971
24
[Radiological picture of maxillary and mandibular neoplasms (analysis of 50 clinical cases)]. 61
5441635 1970
25
[Problem. Mandibular neoplasms]. 61
5207445 1970
26
[Bone grafts for filling bone loss after removal of mandibular neoplasms]. 61
4893931 1969
27
[Contribution to the radiological study of mandibular neoplasms]. 61
13896734 1962
28
[Radical surgery as treatment of oral and mandibular cancer. Experience of 18 cases]. 61
13735734 1961
29
[Radical surgery as the treatment of oral and mandibular cancer. Experience with 18 cases]. 61
13735733 1960
30
[Secondary mandibular cancer]. 61
15444026 1951

Variations for Mandibular Cancer

Expression for Mandibular Cancer

Search GEO for disease gene expression data for Mandibular Cancer.

Pathways for Mandibular Cancer

GO Terms for Mandibular Cancer

Biological processes related to Mandibular Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 8.8 ST7 SERPINB5 COL27A1

Sources for Mandibular Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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