MCID: MRK002
MIFTS: 21

Marek Disease

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Marek Disease

MalaCards integrated aliases for Marek Disease:

Name: Marek Disease 20 70
Neurolymphomatosis 20 58
Marek's Disease 20
Fowl Paralyses 20
Fowl Paralysis 20

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Orphanet 58 ORPHA206586
UMLS 70 C0024793

Summaries for Marek Disease

MalaCards based summary : Marek Disease, also known as neurolymphomatosis, is related to reticuloendotheliosis, x-linked and herpes simplex. An important gene associated with Marek Disease is H19 (H19 Imprinted Maternally Expressed Transcript). Affiliated tissues include salivary gland, testis and tongue.

Related Diseases for Marek Disease

Diseases related to Marek Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 185)
# Related Disease Score Top Affiliating Genes
1 reticuloendotheliosis, x-linked 10.9
2 herpes simplex 10.6
3 newcastle disease 10.6
4 lymphoma 10.6
5 laryngotracheitis 10.5
6 cytokine deficiency 10.5
7 coccidiosis 10.4
8 chickenpox 10.4
9 disease by infectious agent 10.4
10 avian influenza 10.4
11 vasculitis 10.4
12 bronchitis 10.3
13 splenomegaly 10.3
14 kaposi sarcoma 10.3
15 central nervous system lymphoma 10.3
16 deficiency anemia 10.3
17 polyneuropathy 10.3
18 burkitt lymphoma 10.2
19 lymphoproliferative syndrome 10.2
20 plexopathy 10.2
21 primary central nervous system lymphoma 10.2
22 mononeuropathy 10.2
23 atherosclerosis susceptibility 10.2
24 palmoplantar keratoderma, punctate type ii 10.2
25 torticollis 10.2
26 guillain-barre syndrome 10.2
27 neuritis 10.2
28 influenza 10.2
29 punctate porokeratosis 10.2
30 facial paralysis 10.1
31 mononeuritis multiplex 10.1
32 ataxia and polyneuropathy, adult-onset 10.1
33 cryptosporidiosis 10.1
34 tic disorder 10.1
35 brain edema 10.1
36 posttransplant acute limbic encephalitis 10.1
37 cauda equina syndrome 10.1
38 polyradiculoneuropathy 10.1
39 paresthesia 10.1
40 radiculopathy 10.1
41 polyradiculopathy 10.1
42 b-cell non-hodgkin lymphoma 10.1
43 optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy 10.0
44 polykaryocytosis inducer 10.0
45 allergic disease 10.0
46 ovarian lymphoma 10.0
47 demyelinating disease 10.0
48 peripheral nervous system disease 10.0
49 b-cell lymphoma 10.0
50 muscular atrophy 10.0

Graphical network of the top 20 diseases related to Marek Disease:



Diseases related to Marek Disease

Symptoms & Phenotypes for Marek Disease

Drugs & Therapeutics for Marek Disease

Search Clinical Trials , NIH Clinical Center for Marek Disease

Genetic Tests for Marek Disease

Anatomical Context for Marek Disease

MalaCards organs/tissues related to Marek Disease:

40
Salivary Gland, Testis, Tongue

Publications for Marek Disease

Articles related to Marek Disease:

(show top 50) (show all 300)
# Title Authors PMID Year
1
Neurolymphomatosis of the median nerve, optic nerve, L4 spinal nerve root and cauda equina in patients with B-cell malignancies: a case series. 61
33766128 2021
2
Isolated primary neurolymphomatosis with cranial multineuritis: a case presentation. 61
33040194 2021
3
Clinical manifestations of, diagnostic approach to, and treatment of neurolymphomatosis in the rituximab era. 61
33661298 2021
4
Neurolymphomatosis: a single-center experience of neuromuscular manifestations, treatments, and outcomes. 61
33098033 2021
5
Heterogeneous clinical and imaging findings and long-term prognosis in patients with neurolymphomatosis. 61
33346379 2021
6
CIDP mimics: a case series. 61
33639867 2021
7
Extra-hepatic biliary obstruction due to diffuse large B-cell lymphoma: an autopsy case report with unattended yet significant pathologies. 61
32996112 2021
8
FDG PET/CT in Neurolymphomatosis. 61
33107802 2021
9
Mechanisms of Nerve Damage in Neuropathies Associated with Hematological Diseases: Lesson from Nerve Biopsies. 61
33498362 2021
10
Circumdural extension of perineural spread leading to bilateral disease in neurolymphomatosis. 61
32468322 2020
11
Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness. 61
33363793 2020
12
Sciatic and median nerve neurolymphomatosis as initial presentation of B-cell Lymphoma. 61
33358595 2020
13
Peripheral nerve neurolymphomatosis: Clinical features, treatment, and outcomes. 61
32786031 2020
14
Understanding the Pathognomonic Tumefactive Appearance of Neurolymphomatosis: A Unifying Theory of Neurolymphoma. 61
32492544 2020
15
[Neurolymphomatosis Mimicking Inflammatory Neuropathy with Slight FDG Uptake on PET/CT and Distinct MRI Abnormalities in the Brachial Plexus: A Case Report]. 61
32934188 2020
16
Neurolymphomatosis, a rare manifestation of peripheral nerve involvement in lymphomas: Suggestive features and diagnostic challenges. 61
32627254 2020
17
Utility of the 18F-FDG PET/CT in the diagnosis of the neurolymphomatosis: a case report. 61
32868261 2020
18
PET/CT in Evaluation of Low Backache Due to Sacral Nerve Root Involvement: Inflammatory and Malignant Involvement. 61
32349090 2020
19
Primary Central Nervous System Lymphoma With Diffuse Neurolymphomatosis Involving Multiple Cranial and Spinal Nerve Roots. 61
32332304 2020
20
Magnetic Resonance Imaging-negative, Rituximab-resistant Neurolymphomatosis as a Paradoxical Presentation of Relapsed Primary Adrenal Lymphoma. 61
32132335 2020
21
Diffuse large B-cell lymphoma relapse presenting as extensive neurolymphomatosis. 61
32401669 2020
22
Primary peripheral nerve tumors associated with nerve-territory herpes zoster. 61
32193725 2020
23
Neurolymphomatosis - Rare presentation in non-Hodgkin's lymphoma: The role of 18F-fluorodeoxyglucose positron-emission tomography and computerized tomography imaging. 61
32939208 2020
24
Burkitt Lymphoma Presenting as Cranial Multineuritis Secondary to Primary Neurolymphomatosis: A Diagnostic Challenge. 61
32113890 2020
25
Sciatic pain by neurolymphomatosis as initial presentation of disseminated diffuse large B cell lymphoma involving the testis and the CNS. 61
32026488 2020
26
Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence. 61
32134914 2020
27
Protean Manifestations and Diagnostic Challenges Including Discordance Between Electrodiagnostic-Radiologic Studies in Neurolymphomatosis. 61
31876651 2020
28
Magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography/computed tomography findings in neurolymphomatosis: an uncommon presentation of diffuse large B cell lymphoma. 61
31768676 2020
29
Recurrence of nasal type NK/T cell lymphoma presenting as neurolymphomatosis on 18F-FDG PET/CT: A case report and literature review. 61
31895825 2020
30
Neurolymphomatosis of the Sciatic and Tibial Nerves. 61
31779751 2019
31
Diagnostic delay in a case of T-cell neurolymphomatosis. 61
31888900 2019
32
Neurolymphomatosis of the lumbosacral plexus and its branches: case series and literature review. 61
31775683 2019
33
Brachial and sacral plexus neurolymphomatosis - unusual regions for disease relapses. 61
31826141 2019
34
Neurolymphomatosis caused by diffuse large B-cell lymphoma presenting as isolated brachial plexopathy. 61
31765359 2019
35
Putative mechanisms for spread and transformation of cutaneous T-cell lymphoma to neurolymphomatosis. 61
31415100 2019
36
Diagnosis of intravascular large B cell lymphoma: novel insights into clinicopathological features from 42 patients at a single institution over 20 years. 61
31267524 2019
37
Secondary Neurolymphomatosis of the Radial Nerve: A Diagnostic Challenge. 61
31707401 2019
38
[Primary neurolymphomatosis in the cauda equina as the initial symptom of human immunodeficiency virus]. 61
31559629 2019
39
Neurolymphomatosis of the sciatic and tibial nerves as an initial presentation of lung diffuse large B cell lymphoma detected by positron emission tomography/computed tomography. 61
31309418 2019
40
Neuropathies and paraproteins. 61
31313705 2019
41
Teaching NeuroImages: Neurolymphomatosis. 61
31527110 2019
42
18F-FDG PET/CT imaging findings of extensive neurolymphomatosis as a relapse of diffuse large B cell lymphoma. 61
30853415 2019
43
B-cell peripheral neurolymphomatosis: MRI and 18F-FDG PET/CT imaging characteristics. 61
30666391 2019
44
Reasons for evaluation on an emergency basis of and short-term outcomes for chickens from backyard flocks: 78 cases (2014-2017). 61
31039091 2019
45
CD56+ B-cell Neurolymphomatosis in a Cat. 61
31159947 2019
46
Peripheral nervous system involvement in lymphomas. 61
30556258 2019
47
High-grade B-cell lymphoma relapse presenting as neurolymphomatosis of the median nerve. 61
30846458 2019
48
Limited efficacy of high-dose methotrexate in patients with neurolymphomatosis. 61
30604318 2019
49
Diffuse Large B-Cell Lymphoma Recurring as Neurolymphomatosis on FDG PET/CT. 61
30516683 2019
50
Primary neurolymphomatosis of the trigeminal nerve. 61
30741017 2019

Variations for Marek Disease

Expression for Marek Disease

Search GEO for disease gene expression data for Marek Disease.

Pathways for Marek Disease

GO Terms for Marek Disease

Sources for Marek Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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