MCID: MST005
MIFTS: 53

Mastitis

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Mastitis

MalaCards integrated aliases for Mastitis:

Name: Mastitis 12 54 43 15 17 71
Inflammation of Non-Human Mammary Gland 71
Inflammatory Disorder of Breast 71
Inflammatory Disease of Breast 12
Inflammatory Breast Disease 12
Breast Inflammation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10690
MeSH 43 D008413
NCIt 49 C53662
ICD10 32 N61
UMLS 71 C0024894 C3495439 C3668816

Summaries for Mastitis

Disease Ontology : 12 A breast disease characterized by painful infection of the breast tissue.

MalaCards based summary : Mastitis, also known as inflammation of non-human mammary gland, is related to toxic shock syndrome and breast abscess, and has symptoms including signs and symptoms in breast An important gene associated with Mastitis is LTF (Lactotransferrin), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and neutrophil, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Wikipedia : 74 Mastitis is inflammation of the breast or udder, usually associated with breastfeeding. Symptoms... more...

Related Diseases for Mastitis

Diseases related to Mastitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 546)
# Related Disease Score Top Affiliating Genes
1 toxic shock syndrome 33.3 TLR2 LBP IL6 CXCL8
2 breast abscess 33.1 OXT MUC1
3 brucellosis 31.2 IL6 IL17A CXCL8
4 bacterial infectious disease 31.2 TLR2 NOD2 LTF LBP IL6 IL17A
5 exanthem 31.0 IL6 CXCL8 ALB
6 leptospirosis 30.9 TLR2 IL6 CXCL8
7 oral candidiasis 30.9 SLPI LTF IL17A CXCL8
8 proteasome-associated autoinflammatory syndrome 1 30.8 TLR2 IL6 IL17A CXCL8 CCL5
9 candidiasis 30.8 TLR2 IL6 IL17A CXCL8
10 necrotizing fasciitis 30.8 IL6 CXCL8 ALB
11 chlamydia 30.8 TLR2 IL6 IL17A CXCL8
12 dermatitis 30.8 NOD2 IL6 IL17A CXCL8
13 septic arthritis 30.8 TLR2 IL6 CXCL8
14 endometritis 30.7 TLR2 OXT IL6 HP CXCL8
15 pulmonary tuberculosis 30.7 TLR2 IL6 HP ALB
16 aspergillosis 30.7 TLR2 NOD2 IL6 CXCL8 CCL5
17 infective endocarditis 30.7 TLR2 LBP IL6 IL17A
18 haemophilus influenzae 30.7 TLR2 LTF CXCL8
19 endocarditis 30.7 TLR2 LBP IL6 IL17A CXCL8 ALB
20 diabetes mellitus, type i 30.6 TLR2 IL6 IL17A CXCL8 CSN2 ALB
21 mycobacterium abscessus 30.6 TLR2 CXCL8
22 mycobacterium kansasii 30.6 TLR2 CXCL8
23 allergic hypersensitivity disease 30.6 LALBA IL17A CXCL8 CCL5
24 skin disease 30.6 TLR2 IL6 IL17A CXCL8 ALB
25 pasteurellosis 30.6 SLPI CXCL8 ALB
26 relapsing polychondritis 30.6 IL6 IL17A CXCL8
27 echinococcosis 30.5 TLR2 IL6 IL17A
28 pain agnosia 30.5 OXT IL6 ALB
29 systemic autoimmune disease 30.5 IL6 IL17A
30 endophthalmitis 30.5 TLR2 IL6 CXCL8 ALB
31 acute cystitis 30.5 TLR2 IL6 CXCL8 ALB
32 meningoencephalitis 30.5 IL6 CCL5 ALB
33 salmonellosis 30.4 TLR2 IL6 IL17A ALB
34 alpha-1-antitrypsin deficiency 30.4 SLPI CXCL8 ALB
35 peritonitis 30.4 TLR2 LBP IL6 IL17A CXCL8 CCL5
36 allergic asthma 30.4 TLR2 IL17A CXCL8 CCL5
37 connective tissue disease 30.4 MUC1 IL6 IL17A CXCL8 ALB
38 uveitis 30.4 NOD2 IL6 IL17A CXCL8
39 bone inflammation disease 30.3 TLR2 IL6 IL17A CXCL8 ALB
40 osteomyelitis 30.3 TLR2 NOD2 IL6 CXCL8 CCL5
41 keratoconjunctivitis 30.3 IL6 IL17A CXCL8 CCL5 ALB
42 gastroenteritis 30.3 IL6 CXCL8 ALB
43 rhinitis 30.3 IL6 IL17A CXCL8 CCL5 ALB
44 meningitis 30.3 TLR2 LBP IL6 IL17A CXCL8 CCL5
45 bacterial pneumonia 30.2 TLR2 SLPI IL6 IL17A CXCL8 ALB
46 arthritis 30.2 TLR2 NOD2 IL6 IL17A CXCL8 CXCL6
47 reactive arthritis 30.2 TLR2 LTF LBP IL6 IL17A HP
48 bilirubin metabolic disorder 30.2 OXT HP ALB
49 leprosy 3 30.2 TLR2 NOD2 IL6 IL17A CXCL8 ALB
50 vaginal discharge 30.2 SLPI OXT IL6 HP CXCL8

Comorbidity relations with Mastitis via Phenotypic Disease Network (PDN):


Acute Cystitis Fat Necrosis of Breast
Female Breast Cancer Hypertension, Essential
Microglandular Adenosis

Graphical network of the top 20 diseases related to Mastitis:



Diseases related to Mastitis

Symptoms & Phenotypes for Mastitis

UMLS symptoms related to Mastitis:


signs and symptoms in breast

MGI Mouse Phenotypes related to Mastitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.81 ALB CSN2 CSN3 IL17A IL6 LALBA
2 hematopoietic system MP:0005397 9.7 CCL5 CXCL6 HP IL17A IL6 LBP
3 immune system MP:0005387 9.4 ALB CCL5 CXCL6 HP IL17A IL6

Drugs & Therapeutics for Mastitis

Drugs for Mastitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 94)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
2
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
3
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
4 Respiratory System Agents Phase 4
5 Hormones Phase 4
6 glucocorticoids Phase 4
7 Hormone Antagonists Phase 4
8 Hydrocortisone 17-butyrate 21-propionate Phase 4
9 Anti-Asthmatic Agents Phase 4
10 Hydrocortisone-17-butyrate Phase 4
11 Dermatologic Agents Phase 4
12 Hydrocortisone hemisuccinate Phase 4
13 Anti-Inflammatory Agents Phase 4
14 Betamethasone sodium phosphate Phase 4
15 Betamethasone Valerate Phase 4 2152-44-5
16 Betamethasone-17,21-dipropionate Phase 4
17 Betamethasone benzoate Phase 4
18
Clavulanate Approved, Vet_approved Phase 2, Phase 3 58001-44-8 5280980
19
Amoxicillin Approved, Vet_approved Phase 2, Phase 3 26787-78-0 33613
20
Cloxacillin Approved, Investigational, Vet_approved Phase 2, Phase 3 61-72-3 6098
21
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
22
Cefdinir Approved Phase 2, Phase 3 91832-40-5 6915944
23
Azithromycin Approved Phase 3 83905-01-5 447043 55185
24 Antisecretory factor Phase 3
25 Lactams Phase 2, Phase 3
26 beta-Lactams Phase 2, Phase 3
27 beta-Lactamase Inhibitors Phase 2, Phase 3
28 Anti-Bacterial Agents Phase 2, Phase 3
29 Anti-Infective Agents Phase 2, Phase 3
30 Antibiotics, Antitubercular Phase 2, Phase 3
31 Antitubercular Agents Phase 2, Phase 3
32 Cephalosporins Phase 2, Phase 3
33
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
34
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
35
Iodine Approved, Investigational Phase 2 7553-56-2 807
36
Tamoxifen Approved Phase 2 10540-29-1 2733526
37
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
38
Loperamide Approved Phase 2 53179-11-6 3955
39
Pentoxifylline Approved, Investigational Phase 2 6493-05-6 4740
40
Tocopherol Approved, Investigational Phase 2 1406-66-2, 54-28-4 14986
41
Vitamin A Approved, Nutraceutical, Vet_approved Phase 2 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
42
Vitamin E Approved, Nutraceutical, Vet_approved Phase 2 59-02-9 14985
43 Tocotrienol Investigational Phase 2 6829-55-6
44 Analgesics Phase 2
45 Vaccines Phase 2
46 Immunologic Factors Phase 2
47 Antineoplastic Agents, Hormonal Phase 2
48 Estrogen Receptor Modulators Phase 2
49 Estrogen Antagonists Phase 2
50 Estrogen Receptor Antagonists Phase 2

Interventional clinical trials:

(show all 46)
# Name Status NCT ID Phase Drugs
1 A Randomized Controlled Study on the Effectiveness of Local Injection Combined With Topical Steroids vs. Topical Steroids Mono-therapy in the Treatment of Idiopathic Granulomatous Mastitis Recruiting NCT03766997 Phase 4 Compound Betamethasone Injection;Hydrocortisone Butyrate 0.1% Cream
2 Evaluation of Topical Steroids and Surgical Treatment for Idiopathic Granulomatous Mastitis Recruiting NCT02959580 Phase 4 Hydrocortisone Butyrate
3 Antisecretory Factor (AF) Effects on Intraocular-pressure: a Placebo-controlled Randomised Study Unknown status NCT02731118 Phase 3
4 Phase 2/3 Evaluation of Three Lactobacilli Strains Isolated From Human Milk for the Treatment of Infectious Mastitis During the Lactation Period Completed NCT00716183 Phase 2, Phase 3 Beta-lactam antibiotic
5 Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection Completed NCT00197561 Phase 3
6 The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis With Three Groups in Randomized Controlled Trial. Recruiting NCT03756324 Phase 2, Phase 3 CHPM (Chinese Herbal Patent Medicine );Antibiotics Cefdinir Capsules;Antibiotics Cefdinir Capsules
7 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis and Death: a Phase III Double-blind Randomized Clinical Trial Recruiting NCT03199547 Phase 3 Azithromycin;Placebo Oral Tablet
8 Oral Administration of a Probiotic Strain to Pregnant Women: Effects on the Prevention of Lactational Mastitis and on the Eradication of GBS Colonization Unknown status NCT01505361 Phase 1, Phase 2
9 A Randomized, Double-Blind Trial, Comparing the Safety in Mothers and Their Infants and Immunogenicity in Mothers of Live Attenuated Influenza Vaccine (LAIV) to Inactivated Trivalent Influenza Vaccine (TIV) When Administered to Breast Feeding Women Completed NCT01181323 Phase 2
10 Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia Completed NCT03715413 Phase 2 Tamoxifen
11 Evaluation of Antisecretory Factor in Treatment of Severe Traumatic Brain Injury With Multimodal Monitoring Recruiting NCT04117672 Phase 2
12 Antisecretory Factor, Administered as an Enriched Egg Powder, Salovum®, as Supplementary Therapy for Primary Glioblastoma During Concomitant Radio-chemotherapy. Recruiting NCT04116138 Phase 1, Phase 2
13 The Effect of Probiotics on Maintenance of Health in Pregnancy and Infants: a Randomized, Double-blind, Placebo Controlled Study Active, not recruiting NCT03310853 Phase 2
14 Vitamin A Supplementation of Breast Feeding Mothers and Their Neonates at Delivery: Impact on Mother to Child Transmission of HIV During Lactation, HIV Infection Among Women During the Postpartum Year, and Infant Mortality. Active, not recruiting NCT00198718 Phase 2 Vitamin A (retinyl palmitate)
15 A Phase II Study of the Use of Pentoxifylline and a-Tocopherol in the Treatment of Chronic Breast Pain Associated With Breast Radiotherapy Terminated NCT00188669 Phase 2 pentoxifylline;alpha-Tocopherol
16 Acupuncture for Breast Engorgement During Lactation: a Pilot Study. Unknown status NCT03230760
17 Early Screening of Breast Cancer Using Radiation-Free Pressure-Free Optical Scanning Unknown status NCT00671385
18 Early Detection of Breast Disease Using Medical Radiometer - RTM - 01 - RES Unknown status NCT02286583
19 Nutritional Intervention Study, Randomized, Double-blind, Parallel Group to Evaluate the Effect of Lactobacillus Fermentum CECT5716 Consumption on the Incidence of Mastitis Completed NCT02203877
20 A RCT in Sweden of Acupuncture and Care Interventions for the Relief of Inflammatory Symptoms of the Breast During Lactation Completed NCT00405158 Anti-pyretic medication, paracetamol;cefadroxil;penicillin;flucloxacillin
21 Staphylococcus Aureus Carrier Status in Breastfeeding Mothers and Infants and the Risk of Lactation Mastitis: A Large Prospective Study Completed NCT00620984
22 Oral Administration of a Probiotic to Lactating Women: Microbiological, Immunological, Transcriptomics and Metabolomics Effects Completed NCT01124448
23 Ductal Lavage in Non-lactating Female Women With Mastitis: A Single Arm, Observational Study Completed NCT02794688
24 Granulomatous Mastitis Current Approach and Treatment (Multicentric Study) Granulomatous Mastitis Working Group Completed NCT02667132
25 Indian Postpartum Care: A-randomised Trial to Improve Maternal Health Six Weeks After Birth Completed NCT03715218
26 Study of Intervention Nutritional, Multicenter, Randomized, Blind, Parallel Group to Evaluate the Efficacy of Lactobacillus Fermentum CECT5716 to Reduce the Load Bacterial in Potential Pathogens in Milk of Mothers With Breast Pain Completed NCT02093338
27 Effectiveness of a Nursing Education Intervention on Duration of Breastfeeding and on Post-natal Breast Complications in Primiparous Women: a Randomized Controlled Trial Completed NCT02106026
28 Reducing Maternal Stress Due to Infection, Malnutrition and Psychosocial Conditions of Poverty: A New Paradigm for Tackling Infant Stunting Completed NCT02755012
29 New Protocol for Identification of Serious Bacterial Infection in Febrile Newborn Completed NCT03183531
30 Development and Optimization of a GBS Micro Total Analysis System (µTAS) Prototype for the Direct Detection of Group B Streptococci in Vaginal/Anal Specimens From Intrapartum Maternity Patients Completed NCT00322829
31 A 60-Day Clinical Study to Evaluate Nutrilite Ginko Biloba Cistanche Tablets in Relieving the Symptoms of Chronic Fatigue Syndromes Compared to Negative Control Completed NCT02807649
32 Effect of Quiet or Listening to Music While Breastfeeding on the Production and Lipid and Sodium Content of the Milk Completed NCT01893047
33 Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis: a Multicenter, Randomized, Open-labelled, Non-inferior Trial. Recruiting NCT03724903 Corticosteroid therapy
34 Multicenter, Randomized, Double-blind, Controlled Parallel Nutritional Intervention Study to Evaluate the Effect of Consumption During Pregnancy and the Lactation Period of Lactobacillus Fermentum CECT5716 on the Incidence of Mastitis Recruiting NCT04032899
35 Maternal And Neonatal Screening For Group B Streptococci in Fayoum Governrate: A Follow Up Study Recruiting NCT04227730
36 Re-setting the Breast Microbiome to Lower Inflammation and Risk of Cancer. Recruiting NCT03290651
37 Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk: Effects on Breast Cell DNA Methylation, Breast Inflammation,and Weight Recruiting NCT04374747
38 Examining the Cosmetic Results and Patient Satisfaction Achieved With Skin Reducing Nipple Sparing Mastectomy of Ptotic Breast Followed by Delayed-immediate Submuscular Implant Based- Breast Reconstruction Surgery, and Comparing it to Submuscular Delayed- Immediate Implant- Based Breast Reconstruction Procedures After Skin- Sparing Mastectomy. Response-adaptive, Prospective Randomized Clinical Trial Recruiting NCT04345081
39 Examining and Comparing Patient Satisfaction and Long-term Cosmetic Results Achieved With Implant-based Breast Reconstruction Surgery With Submuscular Silicone Implant After Skin Sparing / Areola Sparing / Nipple Sparing Mastectomy and Contralateral Symmetrization (With Mastopexy and/or Silicone Implant and/or Ultrapro Mesh) With Unilateral Simple Mastectomies and With Bilateral Skin-sparing Mastectomies and Implant-based Immediate Breast Reconstructions. Response-adaptive Prospective Randomized, Comparative Clinical Trial Recruiting NCT04356235
40 Comparison of the Cosmetic Results, Quality of Life and Patient Satisfaction Achieved With Round-block and Retroglandular Oncoplastic Breast Conserving Surgeries. Response-adaptive (RAR) Prospective Randomised, Comperative Clinical Study Recruiting NCT04349527
41 Traditional and Complementary Medicine: a Cure for Idiopathic Granulomatous Mastitis? Active, not recruiting NCT04096300
42 FDG-PET Imaging in Complicated Diabetic Foot (Protocol Version Dated 3/01/2004) Active, not recruiting NCT00194298
43 Strategies to Increase Milk Consumption by Young Nepali Children Enrolling by invitation NCT03886467
44 Idiopathic Granulomatous Mastitis Not yet recruiting NCT04424615
45 Continuation of Breastfeeding After Management of Breast Abscesses by Ultrasound-guided Punctures Not yet recruiting NCT03730467
46 The Scope of Tongue-tie in Norway: Its Prevalence and Consequences for Child Health Not yet recruiting NCT04056936

Search NIH Clinical Center for Mastitis

Cochrane evidence based reviews: mastitis

Genetic Tests for Mastitis

Anatomical Context for Mastitis

MalaCards organs/tissues related to Mastitis:

40
Breast, Testes, Neutrophil, Skin, Colon, Liver, Endothelial

Publications for Mastitis

Articles related to Mastitis:

(show top 50) (show all 12251)
# Title Authors PMID Year
1
Crosstalk between coagulation and inflammation in mastitis and metritis in dairy cows. 54 61
19584041 2009
2
Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection. 61 54
16954396 2006
3
Biosensor assay for determination of haptoglobin in bovine milk. 54 61
16569277 2006
4
A new diagnostic indicator using concanavalin a low-affinity lactoferrin levels in mammary gland secretion in mastitic drying cows. 54 61
16462118 2006
5
Acute phase protein concentrations in serum and milk from healthy cows, cows with clinical mastitis and cows with extramammary inflammatory conditions. 54 61
15074326 2004
6
Indicators of inflammation in the diagnosis of mastitis. 61 54
14556695 2003
7
[Do lactoferrin, lysozyme and the lactoperoxidase-thiocyanate-hydrogen peroxide-system cause negative microbiological results in mastitis secretions?]. 54 61
12161968 2002
8
Acute phase response in naturally occurring coliform mastitis. 54 61
11459016 2001
9
Recombinant human protein C expression in the milk of transgenic pigs and the effect on endogenous milk immunoglobulin and transferrin levels. 61 54
11252382 2001
10
Acute phase proteins in serum and milk from dairy cows with clinical mastitis. 54 61
11202551 2001
11
Mastitis and transmission of human immunodeficiency virus through breast milk. 61 54
11131699 2000
12
Mastitis and immunological factors in breast milk of lactating women in Malawi. 54 61
10473515 1999
13
Factors contributing to variation in the proportion of casein in cows' milk true protein: a review of recent INRA experiments. 61 54
9718491 1998
14
Reduced lactational performance following intravenous endotoxin administration to dairy cows. 61 54
1744270 1991
15
Inhibition of Escherichia coli invasion into bovine mammary epithelial cells previously infected by Mycobacterium avium subsp. paratuberculosis. 61
31939335 2020
16
Nanoparticles for treatment of bovine Staphylococcus aureus mastitis. 61
32036717 2020
17
Bovine mastitis and optimal disease management: Dynamic programming analysis. 61
32333977 2020
18
Use of plant extracts and essential oils in the control of bovine mastitis. 61
32388021 2020
19
Magnetic molecularly imprinted polymers used for selective isolation and detection of Staphylococcus aureus. 61
32278983 2020
20
20-hydroxyeicosatetraenoic acid alters endothelial cell barrier integrity independent of oxidative stress and cell death. 61
32032703 2020
21
Cows selected for divergent mastitis susceptibility display a differential liver transcriptome profile after experimental Staphylococcus aureus mammary gland inoculation. 61
32307160 2020
22
Blood perfusion of teat tissue in dairy cows: Changes associated with pre-milking stimulation and machine milking. 61
32389482 2020
23
Upregulated-gene expression of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) via TLRs following NF-κB and MAPKs in bovine mastitis. 61
32243879 2020
24
Randomized controlled non-inferiority trial investigating the effect of 2 selective dry-cow therapy protocols on antibiotic use at dry-off and dry period intramammary infection dynamics. 61
32448572 2020
25
Oxytropis glabra DC. Inhibits Biofilm Formation of Staphylococcus epidermidis by Down-Regulating ica Operon Expression. 61
32072274 2020
26
Bacteriophages and associated endolysins in therapy and prevention of mastitis and metritis in cows: Current knowledge. 61
32507266 2020
27
Genetic diversity and virulence characteristics of Staphylococcus aureus isolates from cases of bovine mastitis. 61
32224210 2020
28
The gut microbiota contributes to the development of Staphylococcus aureus-induced mastitis in mice. 61
32341472 2020
29
Staphylococcus aureus metal acquisition in the mastitic mammary gland. 61
32244043 2020
30
Antibacterial and immunomodulatory effects of Pheromonicin-NM on Escherichia coli-challenged bovine mammary epithelial cells. 61
32413738 2020
31
Randomized controlled trial investigating the effect of 2 selective dry-cow therapy protocols on udder health and performance in the subsequent lactation. 61
32331877 2020
32
Short communication: Barrier characteristics of 3 external teat sealants to prevent bacterial penetration under in vitro conditions using rubber calf-feeding nipples. 61
32331896 2020
33
Novel use of a continuous PECS II block for mastitis pain treatment. 61
32371498 2020
34
Associations of reproductive indices with fertility outcomes, milk yield, and survival in Holstein cows. 61
32359989 2020
35
Development and evaluation of 4 loop-mediated isothermal amplification assays to detect mastitis-causing bacteria in bovine milk samples. 61
32564949 2020
36
Tandem Mass Tag (TMT)-based quantitative proteomics reveals potential targets associated with onset of Sub-clinical Mastitis in cows. 61
32518370 2020
37
Antibiotic dry buffalo therapy: effect of intramammary administration of benzathine cloxacillin against Staphylococcus aureus mastitis in dairy water buffalo. 61
32532337 2020
38
Idiopathic granulomatous mastitis with erythema nodosum: Is it a variant of clinical presentation indicating treatment resistance? A retrospective cohort study. 61
32562354 2020
39
Identification of a novel bacterial taxon associated with bovine mastitis showing a close evolutionary relationship with Elizabethkingia sp. 61
32146293 2020
40
Antimicrobial susceptibility of nine udder pathogens recovered from bovine clinical mastitis milk in Europe 2015-2016: VetPath results. 61
32456822 2020
41
Evaluation of Boron's Adjuvant Activity in Inactive Bacterin Vaccines Using the Mice Model. 61
32557105 2020
42
Comparison of methods for predicting cow composite somatic cell counts. 61
32564958 2020
43
Milk somatic cell count and its relationship with milk yield and quality traits in Italian water buffaloes. 61
32229124 2020
44
Identification and comparison of exosomal microRNAs in the milk and colostrum of two different cow breeds. 61
32220600 2020
45
Culling reasons and risk factors in Estonian dairy cows. 61
32487155 2020
46
Effects of micronutrient supplementation on performance and epigenetic status in dairy cows. 61
32522297 2020
47
Response to Letter to Editor RE: Idiopathic Granulomatous Mastitis with Skin Rupture: A Retrospective Cohort Study of 200 Patients Who Underwent Surgical and Nonsurgical Treatment. 61
32567414 2020
48
Comment on Idiopathic Granulomatous Mastitis with Skin Rupture: A Retrospective Cohort Study of 200 Patients Who Underwent Surgical and Nonsurgical Treatment. 61
32558610 2020
49
Metabolic status is associated with the recovery of milk somatic cell count and milk secretion after lipopolysaccharide-induced mastitis in dairy cows. 61
32253039 2020
50
Impact of Staphylococcus aureus infection on the late lactation goat milk proteome: New perspectives for monitoring and understanding mastitis in dairy goats. 61
32275959 2020

Variations for Mastitis

Expression for Mastitis

Search GEO for disease gene expression data for Mastitis.

Pathways for Mastitis

Pathways related to Mastitis according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.87 TLR2 STAT5A SLPI NOD2 MUC1 LTF
2
Show member pathways
13.32 TLR2 STAT5A IL6 IL17A CXCL8 CXCL6
3
Show member pathways
13.19 STAT5A NOD2 MUC1 LBP IL6 IL17A
4
Show member pathways
12.96 TLR2 STAT5A LBP IL6 CXCL8 CCL5
5
Show member pathways
12.72 TLR2 STAT5A IL6 CXCL8 CCL5
6
Show member pathways
12.45 TLR2 STAT5A NOD2 IL6 IL17A
7
Show member pathways
12.23 IL6 CXCL8 CXCL6 CCL5
8 12.13 NOD2 IL6 CXCL8 CCL5
9 12.11 TLR2 NOD2 LBP IL6
10
Show member pathways
12.1 TLR2 IL6 IL17A CXCL8 CXCL6
11
Show member pathways
11.87 TLR2 MUC1 LBP IL6 CXCL8
12 11.81 NOD2 IL6 CXCL6 CCL5
13
Show member pathways
11.76 TLR2 STAT5A IL6 IL17A
14
Show member pathways
11.73 LBP IL6 A2M
15 11.66 IL6 CXCL8 CXCL6
16
Show member pathways
11.66 TLR2 STAT5A IL6 IL17A
17 11.61 MUC1 LBP IL6 IL17A CXCL8
18 11.56 IL6 CXCL8 CCL5
19 11.54 STAT5A IL6 CXCL8 CSN2
20 11.51 TLR2 IL6 CXCL8
21 11.42 TLR2 IL6 CXCL8
22 11.4 IL6 CXCL8 CCL5
23 11.37 STAT5A IL6 CXCL8
24
Show member pathways
11.32 LBP IL6 IL17A CXCL8 CXCL6
25 11.07 TLR2 IL6 IL17A CXCL8 CXCL6 CCL5
26 10.92 IL6 IL17A CXCL8 CXCL6 CCL5

GO Terms for Mastitis

Cellular components related to Mastitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 SLPI OXT MUC1 LTF LPO LBP
2 extracellular space GO:0005615 9.55 SLPI OXT MUC1 LTF LPO LBP
3 specific granule lumen GO:0035580 9.33 SLPI LTF HP

Biological processes related to Mastitis according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 10.09 TLR2 SLPI NOD2 LTF LBP HP
2 cell-cell signaling GO:0007267 9.95 LALBA IL17A CXCL6 CCL5
3 inflammatory response GO:0006954 9.91 TLR2 IL6 IL17A CXCL8 CXCL6 CCL5
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.88 TLR2 NOD2 LTF IL6
5 cellular response to interleukin-1 GO:0071347 9.83 IL17A CXCL8 CCL5
6 cellular oxidant detoxification GO:0098869 9.82 LPO HP ALB
7 neutrophil chemotaxis GO:0030593 9.81 CXCL8 CXCL6 CCL5
8 defense response to Gram-positive bacterium GO:0050830 9.81 TLR2 LBP LALBA IL6
9 chemokine-mediated signaling pathway GO:0070098 9.8 CXCL8 CXCL6 CCL5
10 cellular response to lipopolysaccharide GO:0071222 9.8 NOD2 LBP IL6 CXCL8 CXCL6
11 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.79 LTF CXCL8 CXCL6
12 defense response to Gram-negative bacterium GO:0050829 9.78 LTF LBP LALBA IL6
13 positive regulation of tumor necrosis factor production GO:0032760 9.77 TLR2 NOD2 LBP
14 defense response GO:0006952 9.77 STAT5A NOD2 HP CXCL8 CXCL6
15 lactation GO:0007595 9.75 STAT5A CSN3 CSN2
16 negative regulation of viral genome replication GO:0045071 9.74 SLPI LTF CCL5
17 acute-phase response GO:0006953 9.72 LBP IL6 HP
18 lipopolysaccharide-mediated signaling pathway GO:0031663 9.71 TLR2 LBP CCL5
19 positive regulation of interleukin-8 production GO:0032757 9.7 TLR2 NOD2 LBP
20 immune response GO:0006955 9.7 TLR2 SLPI IL6 IL17A CXCL8 CXCL6
21 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.67 NOD2 IL6 IL17A
22 response to molecule of bacterial origin GO:0002237 9.65 TLR2 CXCL8
23 cellular response to lipoteichoic acid GO:0071223 9.63 TLR2 LBP
24 positive regulation of chemokine production GO:0032722 9.63 TLR2 LBP IL6
25 positive regulation of toll-like receptor 4 signaling pathway GO:0034145 9.62 LTF LBP
26 negative regulation of macrophage apoptotic process GO:2000110 9.61 NOD2 CCL5
27 negative regulation of cysteine-type endopeptidase activity GO:2000117 9.59 LTF CSN2
28 cytokine secretion involved in immune response GO:0002374 9.56 TLR2 NOD2
29 positive regulation of interleukin-6 production GO:0032755 9.56 TLR2 NOD2 LBP IL6
30 neutrophil activation GO:0042119 9.5 CXCL8 CXCL6 CCL5
31 cytokine-mediated signaling pathway GO:0019221 9.5 STAT5A MUC1 LBP IL6 IL17A CXCL8
32 defense response to bacterium GO:0042742 9.23 SLPI NOD2 LTF LPO LBP LALBA

Molecular functions related to Mastitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CXCL8 CXCL6 CCL5
2 lipopeptide binding GO:0071723 9.26 TLR2 LBP
3 lipopolysaccharide binding GO:0001530 9.13 TLR2 LTF LBP
4 cytokine activity GO:0005125 9.02 IL6 IL17A CXCL8 CXCL6 CCL5

Sources for Mastitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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