MCID: MST019
MIFTS: 33

Mastoiditis

Categories: Ear diseases, Bone diseases

Aliases & Classifications for Mastoiditis

MalaCards integrated aliases for Mastoiditis:

Name: Mastoiditis 12 76 29 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0060322
ICD10 33 H70.9 H70.90
ICD9CM 35 383.9
MeSH 44 D008417
UMLS 73 C0024904

Summaries for Mastoiditis

Disease Ontology : 12 A middle ear disease characterized by an inflammation of the mucosal lining of the mastoid antrum and the mastoid air cell system inside the mastoid process.

MalaCards based summary : Mastoiditis is related to suppurative otitis media and lemierre's syndrome. An important gene associated with Mastoiditis is MALT1 (MALT1 Paracaspase). The drugs Salmon Calcitonin and Calcitonin gene-related peptide have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and skin.

Wikipedia : 76 Mastoiditis is the result of an infection that extends to the air cells of the skull behind the ear.... more...

Related Diseases for Mastoiditis

Diseases related to Mastoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 319)
# Related Disease Score Top Affiliating Genes
1 suppurative otitis media 30.8 CRP SLC29A3
2 lemierre's syndrome 30.0 CRP MTHFR
3 cholesteatoma of middle ear 11.8
4 auditory system disease 11.5
5 trichodentoosseous syndrome 10.9
6 gapo syndrome 10.9
7 immunodeficiency 12 10.9
8 focal labyrinthitis 10.9
9 geniculate ganglionitis 10.9
10 cerebrospinal fluid leak 10.9
11 otitis media 10.8
12 labyrinthitis 10.4
13 otitis externa 10.4
14 petrositis 10.3
15 streptococcal meningitis 10.3 CRP SPEG
16 thrombosis 10.3
17 patulous eustachian tube 10.3
18 acute orbital inflammation 10.3 CRP RHNO1
19 orbital cellulitis 10.3 CRP RHNO1
20 adhesive otitis media 10.3
21 otosclerosis 10.3
22 ethmoid sinusitis 10.2 CRP RHNO1
23 sensorineural hearing loss 10.2
24 otosalpingitis 10.2
25 lateral sinus thrombosis 10.2
26 multiple cranial nerve palsy 10.2 CRP RHNO1
27 ischemic neuropathy 10.1 CRP MTHFR
28 testicular infarct 10.1 CRP MTHFR
29 perilymphatic fistula 10.1
30 riboflavin deficiency 10.1 CRP MTHFR
31 arteritic anterior ischemic optic neuropathy 10.0 CRP MTHFR
32 uterine anomalies 10.0 CRP MTHFR
33 scarlet fever 10.0
34 meningitis 10.0
35 nutritional deficiency disease 10.0 CRP MTHFR
36 carotid stenosis 10.0 CRP MTHFR
37 papilloma 10.0
38 inverted papilloma 10.0
39 branch retinal artery occlusion 9.9 MTHFR RHNO1
40 homocysteinemia 9.9 CRP MTHFR
41 rhabdomyosarcoma 9.9
42 colorectal adenoma 9.9 CRP MTHFR
43 external ear disease 9.9
44 tympanic membrane disease 9.9
45 rosai-dorfman disease 9.9 CRP SLC29A3
46 primary angle-closure glaucoma 9.9 KERA MTHFR
47 epidural abscess 9.9
48 subdural empyema 9.9
49 facial paralysis 9.9
50 embryonal rhabdomyosarcoma 9.9

Comorbidity relations with Mastoiditis via Phenotypic Disease Network (PDN):


Otitis Media

Graphical network of the top 20 diseases related to Mastoiditis:



Diseases related to Mastoiditis

Symptoms & Phenotypes for Mastoiditis

Drugs & Therapeutics for Mastoiditis

Drugs for Mastoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Salmon Calcitonin Approved, Investigational 47931-85-1 16129616
2
Calcitonin gene-related peptide Investigational 83652-28-2
3 Heptavalent Pneumococcal Conjugate Vaccine
4 Vaccines
5 Bone Density Conservation Agents
6 calcitonin

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Impact of Prevnar 13 on Ear Infections in Children Completed NCT01272999
2 Procalcitonin Level and Kinetics in Children With Bacterial Infections Completed NCT00714402
3 Is There Hearing Loss After Acute Mastoiditis Withdrawn NCT00502450

Search NIH Clinical Center for Mastoiditis

Cochrane evidence based reviews: mastoiditis

Genetic Tests for Mastoiditis

Genetic tests related to Mastoiditis:

# Genetic test Affiliating Genes
1 Mastoiditis 29

Anatomical Context for Mastoiditis

MalaCards organs/tissues related to Mastoiditis:

41
Bone, Brain, Skin, Lung, Salivary Gland

Publications for Mastoiditis

Articles related to Mastoiditis:

(show top 50) (show all 275)
# Title Authors Year
1
Acute mastoiditis in an Italian pediatric tertiary medical center: a 15 - year retrospective study. ( 29914542 )
2018
2
National Incidence of Pediatric Mastoiditis in the United States, 2000-2012: Creating a Baseline for Public Health Surveillance. ( 29601460 )
2018
3
Acute mastoiditis with subperiosteal abscess due to emerging infectious agents. ( 29398006 )
2018
4
Pediatric recurrent acute mastoiditis: Risk factors and insights into pathogenesis. ( 29958598 )
2018
5
Acute Mastoiditis Complicated with Concomitant Bezold's Abscess and Lateral Sinus Thrombosis. ( 29755803 )
2018
6
The Impact of the Transcanal Endoscopic Approach and Mastoid Preservation on Recurrence of Primary Acquired Attic Cholesteatoma. ( 29342049 )
2018
7
Changes in the epidemiology and clinical features of acute mastoiditis following the introduction of the pneumococcal conjugate vaccine. ( 29287882 )
2018
8
Mastoiditis. ( 29716974 )
2018
9
Fusobacterium necrophorum as an Emerging Pathogen of Acute Mastoiditis. ( 29596220 )
2018
10
Safety and postoperative adverse events in management of acute mastoiditis in children - 30 Day NSQIP outcomes. ( 29605342 )
2018
11
Cholesteatoma surgery with the canal wall up technique combined with mastoid obliteration: results from primary surgery in 230 consecutive cases. ( 29298539 )
2018
12
Is anticoagulation beneficial in acute mastoiditis complicated by sigmoid sinus thrombosis? ( 29521448 )
2018
13
A Case of Inverted Papilloma of The Mastoid Cavity After Cholesteatoma Surgery. ( 29764790 )
2018
14
Sonographic diagnosis of acute mastoiditis and subsequent retroauricular abscess in a pediatric cochlear implant recipient: A case report. ( 28369924 )
2017
15
Primary Ewing Sarcoma of the Mastoid: A Novel Case Mimicking Acute Mastoiditis. ( 29176463 )
2017
16
Postoperative Mastoid Aeration Following Canal Wall Up Mastoidectomy according to Preoperative Middle Ear Disease: Analysis of Temporal Bone Computed Tomography Scans. ( 28942628 )
2017
17
Two clinical cases of granulomatosis with polyangiitis with isolated otitis media and mastoiditis. ( 29332965 )
2017
18
Pediatric acute mastoiditis in the era of pneumococcal vaccination. ( 29105776 )
2017
19
Radiological Imaging of Rare Intracranial Complications Secondary to Otitis Media and Mastoiditis. ( 28468135 )
2017
20
Mastoiditis: on the rise again? ( 28541113 )
2017
21
Anatomical, functional and quality-of-life results for mastoid and epitympanic obliteration with bioactive glass s53p4: a prospective clinical study. ( 27608143 )
2017
22
Radiological Imaging of Rare Intracranial Complications Secondary to Otitis Media and Mastoiditis. ( 28114208 )
2017
23
Management of paediatric acute mastoiditis: systematic review. ( 28879826 )
2017
24
Outpatient management of pediatric acute mastoiditis. ( 29106885 )
2017
25
Differentiating between rhinosinusitis and mastoiditis surgery from postmortem medical training: A study of two identified skulls and hospital records from early 20th century Coimbra, Portugal. ( 28521908 )
2017
26
AA New Classification System is Helpful in Diagnosing Intracranial Complications of Acute Mastoiditis in CT. ( 28801828 )
2017
27
Acute mastoiditis in children: Middle ear cultures may help in reducing use of broad spectrum antibiotics. ( 28012530 )
2017
28
Clivus erosions following Gradenigo's syndrome-mastoiditis causing VI nerve palsy. ( 26969363 )
2016
29
Acute mastoiditis in children with a cochlear implant. ( 26810295 )
2016
30
Management of acute complicated mastoiditis at an urban, tertiary care pediatric hospital. ( 27796038 )
2016
31
Evaluation of Role of Mastoid Surgery in the Management of Safe Chronic Suppurative Otitis Media. ( 27833868 )
2016
32
Reconstruction of Moderately Constricted Ears by Combining V-Y Advancement of Helical Root, Conchal Cartilage Graft, and Mastoid Hitch. ( 27468330 )
2016
33
Acute Mastoiditis Caused by Streptococcus pneumoniae. ( 27171806 )
2016
34
Chronic Suppurative Otitis Media Complicated With Mastoiditis: An Unusual Presentation of Tuberculosis. ( 27865308 )
2016
35
Reconstruction of low hairline microtia of Treacher Collins syndrome with a hinged mastoid fascial flap. ( 26744099 )
2016
36
Primary Inverted Papilloma of Middle Ear and Mastoid: A Rare Case Report. ( 27190934 )
2016
37
Recurrent Mastoiditis Mimics IgG4 Related Disease: A Potential Diagnostic Pitfall. ( 27091207 )
2016
38
Management of Pediatric Acute Mastoiditis in Israel: Nationwide Survey Among Otorhinolaryngologists and Emergency Pediatricians. ( 27977506 )
2016
39
Predictors of Mastoiditis after Intensity-Modulated Radiotherapy in Nasopharyngeal Carcinoma: A Dose-Volume Analysis. ( 26918040 )
2016
40
Mastoiditis and facial paralysis as initial manifestations of temporal bone systemic diseases - the significance of the histopathological examination. ( 27151715 )
2016
41
Fusobacterium necrophorum otitis and mastoiditis in infants and young toddlers. ( 26951264 )
2016
42
Differentiating Acute Otitis Media and Acute Mastoiditis in Hospitalized Children. ( 27613655 )
2016
43
Severe Acute Otitis Media and Acute Mastoiditis in Adults. ( 27895000 )
2016
44
Cochlear implantation in deaf patients with eosinophilic otitis media using subtotal petrosectomy and mastoid obliteration. ( 27168402 )
2016
45
Sensorineural hearing loss after otitis media with effusion and subacute mastoiditis after viral infections of the upper respiratory tract: A comparative study of conservative and surgical treatment. ( 27657322 )
2016
46
Prognostic effect of pre- and post-admission antibiotic treatment in paediatric acute mastoiditis. ( 27748206 )
2016
47
A Toddler with Rhabdomyosarcoma Presenting as Acute Otitis Media with Mastoid Abscess. ( 27174338 )
2016
48
Clinical Efficacy of a Modified Nagata Method That Retains the Fascia Pedicle of the Mastoid Skin Flap in Auricular Reconstruction of Chinese Microtia Patients. ( 26910682 )
2016
49
The Role of Bacteriologic Studies in Predicting Recurrent Mastoiditis in 456 Patients. ( 27466885 )
2016
50
BraA+n abscess due to Streptococcus intermedius secondary to mastoiditis in a child. ( 26722629 )
2015

Variations for Mastoiditis

Expression for Mastoiditis

Search GEO for disease gene expression data for Mastoiditis.

Pathways for Mastoiditis

GO Terms for Mastoiditis

Sources for Mastoiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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