MCID: MTR010
MIFTS: 46

Mature Teratoma

Categories: Cancer diseases

Aliases & Classifications for Mature Teratoma

MalaCards integrated aliases for Mature Teratoma:

Name: Mature Teratoma 12 15 73
Benign Teratoma 73
Dermoid Cyst 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5566
NCIt 50 C9015
SNOMED-CT 68 42717009 55818009

Summaries for Mature Teratoma

Disease Ontology : 12 A teratoma that is composed exclusively of mature tissues derived from two or three germ layers (ectoderm, mesoderm and\nendoderm).

MalaCards based summary : Mature Teratoma, also known as benign teratoma, is related to teratoma and adenocarcinoma. An important gene associated with Mature Teratoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are fMLP Pathway and Endometrial cancer. The drugs Paclitaxel and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include testis, bone and ovary, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Mature Teratoma

Diseases related to Mature Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 209)
# Related Disease Score Top Affiliating Genes
1 teratoma 31.6 AFP POU5F1 TP53
2 adenocarcinoma 30.5 BRAF KRAS TP53
3 embryonal testis carcinoma 29.9 AFP POU5F1
4 pseudomyxoma peritonei 29.9 KRAS TP53
5 struma ovarii 29.9 BRAF TG
6 testicular yolk sac tumor 29.8 AFP POU5F1
7 malignant teratoma 29.8 AFP POU5F1 TP53
8 sarcoma 29.5 BRAF KRAS POU5F1 TP53
9 central nervous system mature teratoma 12.5
10 pineal region mature teratoma 12.5
11 childhood mature teratoma of the ovary 12.5
12 mature teratoma of the ovary 12.4
13 adult central nervous system mature teratoma 12.2
14 childhood central nervous system mature teratoma 12.2
15 mature gastric teratoma 11.8
16 benign pericardial teratoma 11.2
17 sacrococcygeal teratoma 11.1
18 ovarian fetiform teratoma 11.1
19 ovarian solid teratoma 11.1
20 carcinoid syndrome 10.3
21 germ cells tumors 10.3
22 endodermal sinus tumor 10.3
23 scrotal carcinoma 10.2 AFP TP53
24 pancreatic cystadenocarcinoma 10.2 AFP KRAS
25 rare adenocarcinoma of the breast 10.2 KRAS TP53
26 cryptorchidism, unilateral or bilateral 10.2
27 nevus of ota 10.2 BRAF TP53
28 mutyh-associated polyposis 10.2 KRAS TP53
29 nasal cavity adenocarcinoma 10.2 KRAS TP53
30 spitz nevus 10.2 BRAF TP53
31 pulmonary blastoma 10.2 KRAS TP53
32 biliary papillomatosis 10.2 KRAS TP53
33 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 10.2 KRAS TP53
34 syringocystadenoma papilliferum 10.2 BRAF KRAS
35 acinar cell carcinoma 10.2 AFP TP53
36 squamous cell carcinoma 10.2
37 pleomorphic xanthoastrocytoma 10.2 BRAF TP53
38 biliary tract neoplasm 10.2 KRAS TP53
39 colonic benign neoplasm 10.2 BRAF KRAS
40 liver angiosarcoma 10.2 KRAS TP53
41 brain germinoma 10.2 AFP POU5F1
42 testicular torsion 10.2 PCNA TP53
43 pilocytic astrocytoma 10.2 BRAF KRAS
44 oral leukoplakia 10.2 PCNA TP53
45 central nervous system germ cell tumor 10.2 AFP POU5F1
46 ovarian germ cell cancer 10.2 AFP TG
47 fibrillary astrocytoma 10.2 PCNA TP53
48 ovarian embryonal carcinoma 10.2 AFP POU5F1
49 intratubular embryonal carcinoma 10.2 AFP POU5F1
50 villous adenoma 10.2 BRAF KRAS

Graphical network of the top 20 diseases related to Mature Teratoma:



Diseases related to Mature Teratoma

Symptoms & Phenotypes for Mature Teratoma

GenomeRNAi Phenotypes related to Mature Teratoma according to GeneCards Suite gene sharing:

26 (show all 21)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-11 10.02 KRAS
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 10.02 AFP
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 10.02 TP53
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.02 AFP KRAS TP53
5 Increased shRNA abundance (Z-score > 2) GR00366-A-132 10.02 TP53
6 Increased shRNA abundance (Z-score > 2) GR00366-A-168 10.02 KRAS
7 Increased shRNA abundance (Z-score > 2) GR00366-A-169 10.02 TP53
8 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.02 KRAS
9 Increased shRNA abundance (Z-score > 2) GR00366-A-19 10.02 TP53
10 Increased shRNA abundance (Z-score > 2) GR00366-A-190 10.02 TP53
11 Increased shRNA abundance (Z-score > 2) GR00366-A-192 10.02 AFP
12 Increased shRNA abundance (Z-score > 2) GR00366-A-196 10.02 KRAS
13 Increased shRNA abundance (Z-score > 2) GR00366-A-23 10.02 KRAS
14 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.02 AFP
15 Increased shRNA abundance (Z-score > 2) GR00366-A-35 10.02 TP53
16 Increased shRNA abundance (Z-score > 2) GR00366-A-39 10.02 TP53
17 Increased shRNA abundance (Z-score > 2) GR00366-A-49 10.02 KRAS
18 Increased shRNA abundance (Z-score > 2) GR00366-A-50 10.02 KRAS
19 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.02 AFP KRAS
20 Increased shRNA abundance (Z-score > 2) GR00366-A-93 10.02 KRAS
21 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-3 8.92 BRAF PCNA SMUG1 TP53

MGI Mouse Phenotypes related to Mature Teratoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.8 AFP BRAF KRAS PCNA POU5F1 TG
2 digestive/alimentary MP:0005381 9.72 BRAF KRAS POU5F1 TG TP53
3 liver/biliary system MP:0005370 9.55 AFP BRAF KRAS POU5F1 TP53
4 neoplasm MP:0002006 9.35 AFP BRAF KRAS SMUG1 TP53
5 reproductive system MP:0005389 9.1 AFP BRAF KRAS PCNA POU5F1 TP53

Drugs & Therapeutics for Mature Teratoma

Drugs for Mature Teratoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 90)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
2
Bleomycin Approved, Investigational Phase 3,Phase 2 11056-06-7 5360373
3
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 43805 6857599 5310940 9887054
4
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
5
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
6
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
7
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
8
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 1 135968-09-1
9
Cyclophosphamide Approved, Investigational Phase 3 6055-19-2, 50-18-0 2907
10
Captopril Approved Phase 3 62571-86-2 44093
11
Ribavirin Approved Phase 3 36791-04-5 37542
12
Palivizumab Approved, Investigational Phase 3 188039-54-5
13
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
14
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
15
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
16
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
17
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
18
Vinblastine Approved Phase 3 865-21-4 241903 13342
19
Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
20 Topoisomerase Inhibitors Phase 3,Phase 2
21 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
22 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
23 Anti-Bacterial Agents Phase 3,Phase 2
24 Alkylating Agents Phase 3,Phase 2,Phase 1
25 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
26 Antibiotics, Antitubercular Phase 3,Phase 2
27 Etoposide phosphate Phase 3,Phase 2
28 Antimitotic Agents Phase 3,Phase 2,Phase 1
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
30 Hormones Phase 3,Phase 2,Phase 1
31 Hormone Antagonists Phase 3,Phase 2,Phase 1
32 Antihypertensive Agents Phase 3
33 Immunologic Factors Phase 3,Phase 2,Phase 1
34
protease inhibitors Phase 3
35 Antirheumatic Agents Phase 3
36 HIV Protease Inhibitors Phase 3
37 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
38 Angiotensin-Converting Enzyme Inhibitors Phase 3
39 Immunoglobulins Phase 3,Phase 2,Phase 1
40 Antimetabolites Phase 3
41 Antibodies Phase 3,Phase 2,Phase 1
42 Anti-Infective Agents Phase 3,Phase 2
43 Antibodies, Monoclonal Phase 3,Phase 2,Phase 1
44 Antiviral Agents Phase 3,Phase 2
45 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
46 Cytochrome P-450 CYP3A Inhibitors Phase 3
47 Steroid Synthesis Inhibitors Phase 3
48 Cytochrome P-450 Enzyme Inhibitors Phase 3
49
Hydroxyitraconazole Phase 3
50 Antifungal Agents Phase 3

Interventional clinical trials:

(show all 39)
# Name Status NCT ID Phase Drugs
1 Safety and Efficacy of Antiadhesive Barrier GUARDIX-FL for Women After Laparoscopic Cystectomy Unknown status NCT02097446 Phase 3
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
4 Single-port LC Might be Preferable for Managing Ovarian Dermoid Cyst. Completed NCT02009228 Phase 3
5 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
7 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
10 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
11 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
12 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
13 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
14 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
15 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
16 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
17 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
18 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
19 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
20 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
21 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
22 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
23 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
24 Contribution of the Imaging to the Expression of intégrines αvβ3 for the Characterization of Residual Masses of Non-seminoma Tumors at the End of Chemotherapy Recruiting NCT02317393 Phase 2
25 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2 PD-0332991
26 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
27 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
28 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
29 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
30 Epidural and Spinal Anesthesia Techniques in Pilonidal Dermoid Sinus Surgeries Unknown status NCT02580500 Not Applicable
31 Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK) Unknown status NCT02224677
32 Ovarian Mesial Incision: a New Safe and Fertility-sparing Technique Completed NCT01590030 Not Applicable
33 Serum Caspase 3, Annexin a2 and Soluble Fas Levels and Endometriosis Completed NCT03020108
34 Anterior Mediastinum Teratoma: A Case Report Completed NCT00836121
35 Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Completed NCT00060021 Not Applicable
36 Standard Follow-up Compared With Extended Follow-up in Treating Patients Who Have Undergone Stem Cell Transplantation for Cancer Completed NCT00049465 Not Applicable
37 Corneal Epithelial Autograft for Limbal Dermoid Recruiting NCT03217461 Not Applicable
38 Project: Every Child for Younger Patients With Cancer Recruiting NCT02402244
39 Monitoring Ovarian Cysts in Pregnancy Not yet recruiting NCT03440931

Search NIH Clinical Center for Mature Teratoma

Genetic Tests for Mature Teratoma

Anatomical Context for Mature Teratoma

MalaCards organs/tissues related to Mature Teratoma:

41
Testis, Bone, Ovary, Bone Marrow, Pineal, Lung, Thyroid

Publications for Mature Teratoma

Articles related to Mature Teratoma:

(show top 50) (show all 314)
# Title Authors Year
1
Metastatic mediastinal mature teratoma with malignant transformation in a young man with an adenocarcinoma in a Klinefelter's syndrome: Case report and review of the literature. ( 29673950 )
2018
2
Testicular Yolk Sac Tumor and Mature Teratoma: Synchronous Bilateral Occurrence in an Infant. ( 29608939 )
2018
3
Mature teratoma of the bladder in adolescence: a case report and literature review. ( 29951451 )
2018
4
Squamous Cell Carcinoma Arising in Mature Teratoma of the Ovary Masquerading as Abdominal Tuberculosis. ( 29628730 )
2018
5
Midline Posterior Fossa Mature Teratoma in a Child. ( 30090150 )
2018
6
Diploic mature teratoma originating from the orbital roof: An extremely rare case report. ( 30105145 )
2018
7
Mature teratoma of the pineal region in the paediatric age group: A case report and review of the literature. ( 30173236 )
2018
8
Unusual Radiographic Presentation of Intracranial Mature Teratoma and Resection via a Supraorbital Approach. ( 30368015 )
2018
9
Mediastinal mature teratoma perforating the right lung that was successfully resected with complete thoracoscopic surgery: A case report. ( 30448638 )
2018
10
Adult Thoracic Intradural Exophytic Mature Teratoma: Case Report and Literature Review. ( 30459890 )
2018
11
Peritoneal Nodules in a Pediatric Patient with Benign Teratoma. A Case Report and Review of Literature. ( 29990549 )
2018
12
Mature teratoma of the uterine corpus: A case report. ( 28597671 )
2017
13
Malignant tumors associated with ovarian mature teratoma: A single institution experience. ( 28214217 )
2017
14
Metastatic mature teratoma to the neck with respiratory-type epithelium: a case requiring evidence of chromosome 12p overrepresentation to differentiate malignant and benign diagnoses. ( 28960502 )
2017
15
Malignant transformation of a mature teratoma of the adrenal gland: A rare case report and literature review. ( 29137015 )
2017
16
Mixed pineal mature teratoma and germinoma in two brothers of the fraternal triplets. ( 28236067 )
2017
17
Intradural sacral mature teratoma associated with a low-lying conus. ( 28084287 )
2017
18
Seminoma accompanying mature teratoma in an infantile mediastinal region: A rare presentation of infantile germ cell tumors. ( 27450779 )
2016
19
Cyclin-Dependent Kinase 4/6 Inhibition for the Treatment of Unresectable Mature Teratoma: Long-Term Follow-Up of a Phase II Study. ( 27055371 )
2016
20
Cloacal Exstrophy with Mature Teratoma: A Rare Association in a Neonate. ( 27123401 )
2016
21
Glioblastoma arising within a mediastinal mature teratoma. ( 27327191 )
2016
22
MRI findings in intraspinal mature teratoma. ( 27180081 )
2016
23
Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: case report. ( 27911225 )
2016
24
Giant mature teratoma in the mediastinum presenting with rapid growth. ( 28031857 )
2016
25
Situs inversus totalis with a mature teratoma of the posterior mediastinum: A case report. ( 26893706 )
2016
26
Intramedullary mature teratoma of the conus medullaris. ( 27114670 )
2016
27
Mediastinal Mature Teratoma Revealed by Empyema. ( 27144046 )
2016
28
A case of mature teratoma with a falsely high serum estradiol value measured with an immunoassay. ( 26974135 )
2016
29
Mature Teratoma Confined to the Posterior Fossa. ( 26730985 )
2016
30
Mature Teratoma at Left Lumbar Region in an Infant: A Case Report. ( 28208935 )
2016
31
Mature Teratoma Associated with Bilateral Ovarian Carcinosarcoma - Accidental Association or Etiopathogenetic Determinism? - Case Report. ( 27819640 )
2016
32
Mediastinal mature teratoma in a child- A case report. ( 27130743 )
2016
33
Malignant melanoma arising in a mature teratoma: A case report with review of the recent literature. ( 27331138 )
2016
34
Uterine myometrial mature teratoma presenting as a uterine mass: a review of literature. ( 27011758 )
2016
35
High Frequency of Malignant Transformation of Ovarian Mature Teratoma into Squamous Cell Carcinoma in Young Patients in Northeast Brazil. ( 26367783 )
2015
36
Mature teratoma arising from an undescended testis in a horse: comparison between ultrasonographic and morphological features. ( 26431049 )
2015
37
Ovarian mature teratoma: a ten year experience in our institution. ( 26411224 )
2015
38
Opsoclonus-ataxia syndrome associated with ovarian mature teratoma. ( 25772013 )
2015
39
Successful surgical treatment of mature teratoma arising from the sella. ( 25436031 )
2015
40
Mediastinal mature teratoma with complete gastrointestinal and bronchial walls. ( 26392853 )
2015
41
Rare case of coexistence of primary ovarian carcinoid in mature teratoma with primary serous carcinoma in second ovary--a case report. ( 26189263 )
2015
42
Mature Teratoma in a Supernumerary Ovary in a Child: Report of the First Case. ( 26241889 )
2015
43
Asymptomatic cervical mature teratoma in a child: an unusual presentation. ( 25859464 )
2015
44
Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course. ( 26113666 )
2015
45
Soft palatine mass with diagnosis of mature teratoma. ( 25635601 )
2015
46
Benign Mature Teratoma in Anterior Mediastinum. ( 26251691 )
2015
47
FDG-PET/CT in a Patient with Poor-Risk Non-Seminoma Testis with Mature Teratoma and Secondary Gliosarcoma: Multimodality Imaging for Guiding Multimodality Treatment. ( 26279698 )
2015
48
Mixed carcinoid-mucinous adenocarcinoma arising in mature teratoma of mesentery. ( 25812659 )
2015
49
Primary juxtaovarian yolk sac tumor concurrent with an ipsilateral ovarian mature teratoma in an adult woman: a rare association. ( 25755817 )
2015
50
Intrapulmonary Mature Teratoma Mimicking a Fungus Ball. ( 25749667 )
2015

Variations for Mature Teratoma

Expression for Mature Teratoma

Search GEO for disease gene expression data for Mature Teratoma.

Pathways for Mature Teratoma

Pathways related to Mature Teratoma according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 BRAF KRAS POU5F1 TP53
2
Show member pathways
12.54 BRAF KRAS PCNA TP53
3
Show member pathways
12.23 BRAF KRAS TP53
4 12.17 KRAS PCNA TP53
5 12 BRAF KRAS TP53
6
Show member pathways
11.99 BRAF KRAS TP53
7
Show member pathways
11.96 BRAF KRAS TP53
8 11.87 BRAF KRAS TP53
9 11.85 BRAF KRAS PCNA
10
Show member pathways
11.82 BRAF KRAS TP53
11 11.77 BRAF KRAS TP53
12
Show member pathways
11.73 BRAF KRAS TP53
13 11.62 AFP PCNA TP53
14 11.55 BRAF KRAS TP53
15 11.38 BRAF KRAS TP53
16 11.29 KRAS PCNA TP53
17 11.26 PCNA TP53
18 11.23 BRAF KRAS
19 11.16 BRAF PCNA TP53
20 11.11 BRAF KRAS
21 11.07 PCNA TP53
22 11.01 PCNA TP53
23 10.97 BRAF KRAS
24 10.66 BRAF KRAS TP53

GO Terms for Mature Teratoma

Biological processes related to Mature Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 base-excision repair GO:0006284 9.32 SMUG1 TP53
2 thyroid gland development GO:0030878 9.26 BRAF TG
3 cellular response to DNA damage stimulus GO:0006974 9.26 PCNA SMUG1 TP53 ZBTB38
4 regulation of DNA replication GO:0006275 9.16 PCNA ZBTB38
5 positive regulation of gene expression GO:0010628 8.92 BRAF KRAS POU5F1 TP53

Molecular functions related to Mature Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone acetyltransferase binding GO:0035035 8.62 PCNA TP53

Sources for Mature Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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