MCID: MTR011
MIFTS: 26

Mature Teratoma of the Ovary

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Mature Teratoma of the Ovary

MalaCards integrated aliases for Mature Teratoma of the Ovary:

Name: Mature Teratoma of the Ovary 12 15
Mature Teratoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6231
NCIt 50 C8112
UMLS 73 C1334637

Summaries for Mature Teratoma of the Ovary

Disease Ontology : 12 An ovarian biphasic or triphasic teratoma that is composed exclusively of mature tissues derived from two or three germ layers (ectoderm, mesoderm and endoderm).

MalaCards based summary : Mature Teratoma of the Ovary, also known as mature teratoma of ovary, is related to childhood mature teratoma of the ovary and ovarian fetiform teratoma. An important gene associated with Mature Teratoma of the Ovary is NECTIN2 (Nectin Cell Adhesion Molecule 2), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include ovary, spinal cord and thyroid.

Related Diseases for Mature Teratoma of the Ovary

Graphical network of the top 20 diseases related to Mature Teratoma of the Ovary:



Diseases related to Mature Teratoma of the Ovary

Symptoms & Phenotypes for Mature Teratoma of the Ovary

Drugs & Therapeutics for Mature Teratoma of the Ovary

Search Clinical Trials , NIH Clinical Center for Mature Teratoma of the Ovary

Genetic Tests for Mature Teratoma of the Ovary

Anatomical Context for Mature Teratoma of the Ovary

MalaCards organs/tissues related to Mature Teratoma of the Ovary:

41
Ovary, Spinal Cord, Thyroid, Breast

Publications for Mature Teratoma of the Ovary

Articles related to Mature Teratoma of the Ovary:

# Title Authors Year
1
Squamous Cell Carcinoma Arising in Mature Teratoma of the Ovary Masquerading as Abdominal Tuberculosis. ( 29628730 )
2018
2
Gliomatosis peritonei with mature teratoma of the ovary. ( 12722472 )
2002
3
Glomus tumor arising in a mature teratoma of the ovary: report of a case simulating a metastasis from cervical squamous carcinoma. ( 10975942 )
2000
4
Mature teratoma of the ovary with predominant benign anlage component. Report of a case. ( 10410893 )
1999
5
Metastasis of a breast carcinoma in a mature teratoma of the ovary. ( 10410892 )
1999
6
Endoscopic surgery for mature teratoma of the ovary. ( 8703147 )
1996
7
Solid mature teratoma of the ovary: appearances at MR imaging. ( 8025887 )
1994

Variations for Mature Teratoma of the Ovary

Expression for Mature Teratoma of the Ovary

Search GEO for disease gene expression data for Mature Teratoma of the Ovary.

Pathways for Mature Teratoma of the Ovary

Pathways related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.49 CD226 NECTIN2 PVR
2 11.26 CD226 NECTIN2 PVR
3 10.65 NECTIN2 PVR
4 10.56 CD226 NECTIN2 PVR

GO Terms for Mature Teratoma of the Ovary

Cellular components related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.8 CD226 NECTIN2 PVR

Biological processes related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.65 CD226 NECTIN2 PVR
2 regulation of immune response GO:0050776 9.61 CD226 NECTIN2 PVR
3 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.49 NECTIN2 PVR
4 adherens junction organization GO:0034332 9.46 NECTIN2 PVR
5 positive regulation of T cell receptor signaling pathway GO:0050862 9.4 CD226 NECTIN2
6 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.37 NECTIN2 PVR
7 positive regulation of mast cell activation GO:0033005 9.32 CD226 NECTIN2
8 positive regulation of immunoglobulin mediated immune response GO:0002891 9.26 CD226 NECTIN2
9 susceptibility to T cell mediated cytotoxicity GO:0060370 9.16 NECTIN2 PVR
10 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9.13 CD226 NECTIN2 PVR
11 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 8.8 CD226 NECTIN2 PVR

Molecular functions related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 8.96 NECTIN2 PVR
2 cell adhesion molecule binding GO:0050839 8.8 CD226 NECTIN2 PVR

Sources for Mature Teratoma of the Ovary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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