MCID: MTR011
MIFTS: 24

Mature Teratoma of the Ovary

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Mature Teratoma of the Ovary

MalaCards integrated aliases for Mature Teratoma of the Ovary:

Name: Mature Teratoma of the Ovary 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:6231
NCIt 49 C8112
UMLS 71 C1334637

Summaries for Mature Teratoma of the Ovary

Disease Ontology : 12 An ovarian biphasic or triphasic teratoma that is composed exclusively of mature tissues derived from two or three germ layers (ectoderm, mesoderm and endoderm).

MalaCards based summary : Mature Teratoma of the Ovary is related to teratoma and ovarian germ cell teratoma. An important gene associated with Mature Teratoma of the Ovary is SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5), and among its related pathways/superpathways is Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include ovary, thyroid and breast.

Related Diseases for Mature Teratoma of the Ovary

Diseases related to Mature Teratoma of the Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 110)
# Related Disease Score Top Affiliating Genes
1 teratoma 30.5 ENO2 CEACAM5 AFP
2 ovarian germ cell teratoma 29.7 TG SIGLEC5 AFP
3 cystic teratoma 29.6 ENO2 CEACAM5 AFP
4 mature teratoma 29.6 TG ENO2 CEACAM5 AFP
5 ovarian germ cell cancer 29.4 TG CEACAM5 AFP
6 childhood mature teratoma of the ovary 12.8
7 ovarian fetiform teratoma 11.4
8 ovarian solid teratoma 11.4
9 adult type testicular granulosa cell tumor 10.4 MLANA AFP
10 hepatic angiomyolipoma 10.3 MLANA AFP
11 cervical serous adenocarcinoma 10.2 MLANA CEACAM5
12 vulval paget's disease 10.2 MLANA CEACAM5
13 liver lipoma 10.2 CEACAM5 AFP
14 anal paget's disease 10.2 MLANA CEACAM5
15 urachal adenocarcinoma 10.2 CEACAM5 AFP
16 gestational ovarian choriocarcinoma 10.2 CEACAM5 AFP
17 rectum signet ring adenocarcinoma 10.2 CEACAM5 AFP
18 renal pelvis adenocarcinoma 10.2 CEACAM5 AFP
19 bile duct cystadenocarcinoma 10.2 CEACAM5 AFP
20 liver leiomyoma 10.2 CEACAM5 AFP
21 adult teratoma 10.2 CEACAM5 AFP
22 colonic lymphangioma 10.2 CEACAM5 AFP
23 lymphangitis 10.2 SIGLEC5 CEACAM5
24 ovarian mixed germ cell neoplasm 10.2 CEACAM5 AFP
25 liver sarcoma 10.2 CEACAM5 AFP
26 benign mesothelioma 10.2 CEACAM5 AFP
27 biliary tract benign neoplasm 10.2 CEACAM5 AFP
28 sarcomatous intrahepatic cholangiocarcinoma 10.2 CEACAM5 AFP
29 penis sarcoma 10.2 MLANA ENO2
30 bile duct cysts 10.1 CEACAM5 AFP
31 borst-jadassohn intraepidermal carcinoma 10.1 MLANA CEACAM5
32 paget disease, extramammary 10.1 MLANA CEACAM5
33 meningeal melanocytoma 10.1 MLANA ENO2
34 sweat gland disease 10.1 SIGLEC5 CEACAM5
35 hemorrhoid 10.1 MLANA CEACAM5
36 hepatoid adenocarcinoma 10.1 CEACAM5 AFP
37 pineal region teratoma 10.1 ENO2 AFP
38 klatskin's tumor 10.1 CEACAM5 AFP
39 sensory organ benign neoplasm 10.1 MLANA ENO2
40 malignant granular cell myoblastoma 10.1 MLANA ENO2
41 central nervous system melanocytic neoplasm 10.1 MLANA ENO2
42 malignant triton tumor 10.1 MLANA ENO2
43 pineoblastoma 10.1 CEACAM5 AFP
44 cystitis cystica 10.1 UPK2 CEACAM5
45 olfactory nerve neoplasm 10.1 MLANA ENO2
46 liver leiomyosarcoma 10.1 ENO2 AFP
47 cranial nerve malignant neoplasm 10.1 MLANA ENO2
48 cranial nerve neoplasm 10.1 MLANA ENO2
49 subleukemic leukemia 10.1 MLANA ENO2
50 pineal gland cancer 10.1 ENO2 AFP

Graphical network of the top 20 diseases related to Mature Teratoma of the Ovary:



Diseases related to Mature Teratoma of the Ovary

Symptoms & Phenotypes for Mature Teratoma of the Ovary

Drugs & Therapeutics for Mature Teratoma of the Ovary

Search Clinical Trials , NIH Clinical Center for Mature Teratoma of the Ovary

Genetic Tests for Mature Teratoma of the Ovary

Anatomical Context for Mature Teratoma of the Ovary

MalaCards organs/tissues related to Mature Teratoma of the Ovary:

40
Ovary, Thyroid, Breast, Skin, Testes

Publications for Mature Teratoma of the Ovary

Articles related to Mature Teratoma of the Ovary:

(show all 31)
# Title Authors PMID Year
1
Clinical approach to the diagnosis and successful management of anti-NMDA receptor encephalitis when antibody testing is not possible. 61
31604715 2019
2
Sebaceous carcinoma in a mature teratoma of the ovary. 61
30775330 2018
3
Squamous Cell Carcinoma Arising in Mature Teratoma of the Ovary Masquerading as Abdominal Tuberculosis. 61
29628730 2018
4
Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report. 61
28248120 2017
5
Rare Skin Adnexal and Melanocytic Tumors Arising in Ovarian Mature Cystic Teratomas: A Report of 3 Cases and Review of the Literature. 61
26974995 2016
6
Clinical and histological profile of surgically managed benign adnexal masses. 61
24936279 2014
7
A rare case of follicular thyroid carcinoma in ovarian struma. 61
18939380 2008
8
[Abdominal colic caused by mature cystic teratoma of the ovary]. 61
17068669 2007
9
[Mature cystic teratoma of the ovary with a small ganglioneuroma]. 61
16789685 2006
10
Mature ovarian teratoma with gliomatosis peritonei--a case report. 61
16276020 2005
11
An ovarian mucinous adenocarcinoma arising from mature cystic teratoma associated with respiratory type tissue: a case report. 61
15656343 2004
12
A solid mature teratoma of a feline ovary. 61
14623205 2003
13
Gliomatosis peritonei with mature teratoma of the ovary. 61
12722472 2002
14
[Diagnostic image (24). Ovary with a mature teratoma (so-called dermoid cyst)]. 61
11236373 2001
15
Excision of mature teratoma using culdotomy, with and without laparoscopy: a prospective randomised trial. 61
11213011 2001
16
Struma ovarii mimicking a benign multicystic ovarian tumor: MR imaging in one case. 61
11392106 2000
17
Glomus tumor arising in a mature teratoma of the ovary: report of a case simulating a metastasis from cervical squamous carcinoma. 61
10975942 2000
18
Disseminated carcinomatosis after laparoscopic surgery for presumably benign ruptured ovarian teratoma. 61
10733031 2000
19
Metastasis of a breast carcinoma in a mature teratoma of the ovary. 61
10410892 1999
20
Mature teratoma of the ovary with predominant benign anlage component. Report of a case. 61
10410893 1999
21
[Autoimmune hemolytic anemia associated with a mature ovarian teratoma]. 61
10223111 1998
22
Goblet cell carcinoid arising in a mature teratoma of the mediastinum. 61
8990147 1997
23
Endoscopic surgery for mature teratoma of the ovary. 61
8703147 1996
24
Solid mature teratoma of the ovary: appearances at MR imaging. 61
8025887 1994
25
Complications and bilaterality of mature ovarian teratomas (clinicopathological evaluation of 286 cases). 61
1872783 1991
26
[Mature teratoma of the ovary--a clinicopathologic study of 214 teratomas of the ovary]. 61
3454709 1986
27
[Peritoneal gliomatosis associated with a mature teratoma of the ovary]. 61
4015762 1985
28
[Mature teratoma of the ovary with carcinoma]. 61
6732101 1984
29
[Mature teratoma of the ovary. Clinical and anatomo-pathological considerations on 239 cases]. 61
6760772 1982
30
[Carcinoid in a mature teratoma of the ovary]. 61
7224036 1981
31
Covert bilaterality of mature ovarian teratomas. 61
927754 1977

Variations for Mature Teratoma of the Ovary

Expression for Mature Teratoma of the Ovary

Search GEO for disease gene expression data for Mature Teratoma of the Ovary.

Pathways for Mature Teratoma of the Ovary

Pathways related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 SLAMF6 SIGLEC5 NECTIN2 CD226

GO Terms for Mature Teratoma of the Ovary

Biological processes related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.71 SIGLEC5 NECTIN2 CEACAM5 CD226
2 regulation of immune response GO:0050776 9.54 SLAMF6 NECTIN2 CD226
3 positive regulation of interferon-gamma production GO:0032729 9.43 SLAMF6 CD226
4 positive regulation of T cell receptor signaling pathway GO:0050862 9.32 NECTIN2 CD226
5 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.26 NECTIN2 CD226
6 positive regulation of mast cell activation GO:0033005 9.16 NECTIN2 CD226
7 positive regulation of immunoglobulin mediated immune response GO:0002891 8.96 NECTIN2 CD226
8 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 8.8 SLAMF6 NECTIN2 CD226

Molecular functions related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.36 UPK2 UNC5CL TG SLAMF6 SIGLEC5 NECTIN2

Sources for Mature Teratoma of the Ovary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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