MCID: MTR011
MIFTS: 25

Mature Teratoma of the Ovary

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Mature Teratoma of the Ovary

MalaCards integrated aliases for Mature Teratoma of the Ovary:

Name: Mature Teratoma of the Ovary 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:6231
NCIt 50 C8112
UMLS 71 C1334637

Summaries for Mature Teratoma of the Ovary

Disease Ontology : 12 An ovarian biphasic or triphasic teratoma that is composed exclusively of mature tissues derived from two or three germ layers (ectoderm, mesoderm and endoderm).

MalaCards based summary : Mature Teratoma of the Ovary is related to mature teratoma and childhood mature teratoma of the ovary. An important gene associated with Mature Teratoma of the Ovary is SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Cell adhesion molecules. Affiliated tissues include ovary and thyroid.

Related Diseases for Mature Teratoma of the Ovary

Diseases related to Mature Teratoma of the Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 mature teratoma 31.1 ENO2 AFP
2 childhood mature teratoma of the ovary 11.7
3 ovarian fetiform teratoma 11.3
4 ovarian solid teratoma 11.3
5 teratoma 10.7
6 adult type testicular granulosa cell tumor 10.2 MLANA AFP
7 hepatic angiomyolipoma 10.2 MLANA AFP
8 sex cord-gonadal stromal tumor 10.2 MLANA AFP
9 immature teratoma of ovary 10.1 TG AFP
10 middle ear adenocarcinoma 10.1 TG AFP
11 middle ear carcinoma 10.1 TG AFP
12 mycobacterium tuberculosis 1 10.1
13 abdominal tuberculosis 10.1
14 endometriosis of ovary 10.1
15 squamous cell carcinoma 10.1
16 glomus tumor 10.1
17 ovarian brenner tumor 10.1
18 cystic teratoma 10.1
19 endometriosis 10.1
20 sebaceous adenocarcinoma 10.1
21 gliomatosis peritonei 10.1
22 penis sarcoma 10.1 MLANA ENO2
23 ovarian benign neoplasm 10.1 TG AFP
24 meningeal melanocytoma 10.1 MLANA ENO2
25 ovarian germ cell cancer 10.1 TG AFP
26 central nervous system melanocytic neoplasm 10.1 MLANA ENO2
27 sensory organ benign neoplasm 10.1 MLANA ENO2
28 pineal region teratoma 10.1 ENO2 AFP
29 malignant granular cell myoblastoma 10.1 MLANA ENO2
30 paratesticular lipoma 10.1 ENO2 AFP
31 lipoma of spermatic cord 10.1 ENO2 AFP
32 olfactory nerve neoplasm 10.1 MLANA ENO2
33 cranial nerve malignant neoplasm 10.1 MLANA ENO2
34 liver leiomyosarcoma 10.1 ENO2 AFP
35 cranial nerve neoplasm 10.0 MLANA ENO2
36 mediastinal cancer 10.0 ENO2 AFP
37 subleukemic leukemia 10.0 MLANA ENO2
38 pineal gland cancer 10.0 ENO2 AFP
39 adrenal cortex disease 10.0 TG MLANA
40 malignant teratoma 10.0 ENO2 AFP
41 obstructive hydrocephalus 10.0 ENO2 AFP
42 granular cell tumor 10.0 MLANA ENO2
43 sertoli-leydig cell tumor 10.0 ENO2 AFP
44 mixed cell type cancer 10.0 ENO2 AFP
45 sertoli cell tumor 10.0 ENO2 AFP
46 connective tissue benign neoplasm 10.0 MLANA ENO2
47 tubular adenocarcinoma 10.0 ENO2 AFP
48 atypical follicular adenoma 10.0 TG ENO2
49 ovarian germ cell teratoma 10.0 TG SIGLEC5 AFP
50 carotid body cancer 10.0 TG ENO2

Graphical network of the top 20 diseases related to Mature Teratoma of the Ovary:



Diseases related to Mature Teratoma of the Ovary

Symptoms & Phenotypes for Mature Teratoma of the Ovary

Drugs & Therapeutics for Mature Teratoma of the Ovary

Search Clinical Trials , NIH Clinical Center for Mature Teratoma of the Ovary

Genetic Tests for Mature Teratoma of the Ovary

Anatomical Context for Mature Teratoma of the Ovary

MalaCards organs/tissues related to Mature Teratoma of the Ovary:

40
Ovary, Thyroid

Publications for Mature Teratoma of the Ovary

Articles related to Mature Teratoma of the Ovary:

(show all 31)
# Title Authors PMID Year
1
Clinical approach to the diagnosis and successful management of anti-NMDA receptor encephalitis when antibody testing is not possible. 61
31604715 2019
2
Sebaceous carcinoma in a mature teratoma of the ovary. 61
30775330 2018
3
Squamous Cell Carcinoma Arising in Mature Teratoma of the Ovary Masquerading as Abdominal Tuberculosis. 61
29628730 2018
4
Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report. 61
28248120 2017
5
Rare Skin Adnexal and Melanocytic Tumors Arising in Ovarian Mature Cystic Teratomas: A Report of 3 Cases and Review of the Literature. 61
26974995 2016
6
Clinical and histological profile of surgically managed benign adnexal masses. 61
24936279 2014
7
A rare case of follicular thyroid carcinoma in ovarian struma. 61
18939380 2008
8
[Abdominal colic caused by mature cystic teratoma of the ovary]. 61
17068669 2007
9
[Mature cystic teratoma of the ovary with a small ganglioneuroma]. 61
16789685 2006
10
Mature ovarian teratoma with gliomatosis peritonei--a case report. 61
16276020 2005
11
An ovarian mucinous adenocarcinoma arising from mature cystic teratoma associated with respiratory type tissue: a case report. 61
15656343 2004
12
A solid mature teratoma of a feline ovary. 61
14623205 2003
13
Gliomatosis peritonei with mature teratoma of the ovary. 61
12722472 2002
14
[Diagnostic image (24). Ovary with a mature teratoma (so-called dermoid cyst)]. 61
11236373 2001
15
Excision of mature teratoma using culdotomy, with and without laparoscopy: a prospective randomised trial. 61
11213011 2001
16
Struma ovarii mimicking a benign multicystic ovarian tumor: MR imaging in one case. 61
11392106 2000
17
Glomus tumor arising in a mature teratoma of the ovary: report of a case simulating a metastasis from cervical squamous carcinoma. 61
10975942 2000
18
Disseminated carcinomatosis after laparoscopic surgery for presumably benign ruptured ovarian teratoma. 61
10733031 2000
19
Metastasis of a breast carcinoma in a mature teratoma of the ovary. 61
10410892 1999
20
Mature teratoma of the ovary with predominant benign anlage component. Report of a case. 61
10410893 1999
21
[Autoimmune hemolytic anemia associated with a mature ovarian teratoma]. 61
10223111 1998
22
Goblet cell carcinoid arising in a mature teratoma of the mediastinum. 61
8990147 1997
23
Endoscopic surgery for mature teratoma of the ovary. 61
8703147 1996
24
Solid mature teratoma of the ovary: appearances at MR imaging. 61
8025887 1994
25
Complications and bilaterality of mature ovarian teratomas (clinicopathological evaluation of 286 cases). 61
1872783 1991
26
[Mature teratoma of the ovary--a clinicopathologic study of 214 teratomas of the ovary]. 61
3454709 1986
27
[Peritoneal gliomatosis associated with a mature teratoma of the ovary]. 61
4015762 1985
28
[Mature teratoma of the ovary with carcinoma]. 61
6732101 1984
29
[Mature teratoma of the ovary. Clinical and anatomo-pathological considerations on 239 cases]. 61
6760772 1982
30
[Carcinoid in a mature teratoma of the ovary]. 61
7224036 1981
31
Covert bilaterality of mature ovarian teratomas. 61
927754 1977

Variations for Mature Teratoma of the Ovary

Expression for Mature Teratoma of the Ovary

Search GEO for disease gene expression data for Mature Teratoma of the Ovary.

Pathways for Mature Teratoma of the Ovary

GO Terms for Mature Teratoma of the Ovary

Biological processes related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.76 SIGLEC5 PVR NECTIN2 CD226
2 regulation of immune response GO:0050776 9.67 SLAMF6 PVR NECTIN2 CD226
3 positive regulation of interferon-gamma production GO:0032729 9.49 SLAMF6 CD226
4 adherens junction organization GO:0034332 9.48 PVR NECTIN2
5 positive regulation of T cell receptor signaling pathway GO:0050862 9.43 NECTIN2 CD226
6 positive regulation of mast cell activation GO:0033005 9.4 NECTIN2 CD226
7 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.32 PVR NECTIN2
8 positive regulation of immunoglobulin mediated immune response GO:0002891 9.26 NECTIN2 CD226
9 susceptibility to T cell mediated cytotoxicity GO:0060370 9.16 PVR NECTIN2
10 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.13 PVR NECTIN2 CD226
11 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 8.92 SLAMF6 PVR NECTIN2 CD226

Molecular functions related to Mature Teratoma of the Ovary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion molecule binding GO:0050839 8.8 PVR NECTIN2 CD226

Sources for Mature Teratoma of the Ovary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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