MCID: MXL017
MIFTS: 31

Maxillary Cancer

Categories: Bone diseases, Cancer diseases, Oral diseases

Aliases & Classifications for Maxillary Cancer

MalaCards integrated aliases for Maxillary Cancer:

Name: Maxillary Cancer 12 15
Maxillary Neoplasms 44 70
Maxillary Neoplasm 12 17
Upper Jaw Bone Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4618
MeSH 44 D008441
SNOMED-CT 67 126550004
UMLS 70 C0024954

Summaries for Maxillary Cancer

Disease Ontology : 12 A jaw cancer that effects the maxilla or upper jaw.

MalaCards based summary : Maxillary Cancer, also known as maxillary neoplasms, is related to maxillary sinus cancer and sinus cancer. An important gene associated with Maxillary Cancer is PCBP4 (Poly(RC) Binding Protein 4), and among its related pathways/superpathways are BRCA1 Pathway and Signaling events mediated by HDAC Class I. Affiliated tissues include bone, lymph node and salivary gland.

Related Diseases for Maxillary Cancer

Diseases related to Maxillary Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 maxillary sinus cancer 10.1
2 sinus cancer 10.1
3 lymphoma, hodgkin, classic 9.8
4 osteogenic sarcoma 9.8
5 lymphoma, non-hodgkin, familial 9.8
6 ewing sarcoma 9.8
7 osteonecrosis 9.8
8 erysipelas 9.8
9 facial paralysis 9.8
10 myoepithelial carcinoma 9.8
11 keratinizing squamous cell carcinoma 9.8
12 maxillary sinus squamous cell carcinoma 9.8
13 cataract 9.8
14 meningitis 9.8
15 oral cancer 9.8
16 chronic pain 9.8
17 jaw cancer 8.5 PROM2 PCBP4 ITPKB GRHL1 EPPK1 CLCA2

Graphical network of the top 20 diseases related to Maxillary Cancer:



Diseases related to Maxillary Cancer

Symptoms & Phenotypes for Maxillary Cancer

Drugs & Therapeutics for Maxillary Cancer

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 PEEK Versus Metallic Attachment-retained Obturators Regarding Patient Satisfaction: A Randomized Controlled Trial. Completed NCT04778254
2 Aesthetic Reconstruction of Onco-surgical Maxillary Defects Using Free Scapular Flap With and Without CAD/CAM Customized Osteotomy Guide (A Randomized Controlled Clinical Trial) Recruiting NCT03757286
3 Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: An Open-Label, Prospective Pilot Clinical Study Recruiting NCT03057223
4 Is the Maxillectomy Patient's Quality of Life Affected by Palatal Defect Reconstruction Via Scapular Free Flab or Obturator? A Randomized Clinical Trial Active, not recruiting NCT04752046
5 Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps Not yet recruiting NCT04522700
6 Computer-Assisted Jaw Reconstruction Using 3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates: A Randomised Controlled Clinical Trial Not yet recruiting NCT04635865

Search NIH Clinical Center for Maxillary Cancer

Cochrane evidence based reviews: maxillary neoplasms

Genetic Tests for Maxillary Cancer

Anatomical Context for Maxillary Cancer

MalaCards organs/tissues related to Maxillary Cancer:

40
Bone, Lymph Node, Salivary Gland, Brain

Publications for Maxillary Cancer

Articles related to Maxillary Cancer:

(show top 50) (show all 199)
# Title Authors PMID Year
1
A case of maxillary cancer treated by intra-arterial therapy using a steerable microcatheter. 61
33412974 2021
2
Malignant tumors of the maxillary sinus: Prognostic impact of neurovascular invasion in a series of 138 patients. 61
32298995 2020
3
Early Buried Bumper Syndrome Treated by Bedside Replacement 61
32378825 2020
4
The Free Serratus-Rib Flap for Orbital Floor Reconstruction After Oncologic Resection. 61
31923011 2020
5
Effectiveness of chemoradiotherapy for radiation-induced bilateral external auditory canal cancer: A case report and literature review. 61
30828909 2019
6
Technique for secondary modification after maxillary resection and reconstruction for soft tissue flap fixation before prosthesis addition: a case report. 61
31226972 2019
7
Ankylosis of the Coronoid Process to the Zygomatic Bone: A Case Report and Review of the Literature. 61
30439329 2019
8
Salvage surgery for a locally persistent or recurrent tumour in maxillary cancer patients who have undergone radiotherapy and concomitant intra-arterial cisplatin: implications for surgical margin assessment. 61
30447876 2019
9
Intraoperative verification of resection margins of maxillary malignancies by cone-beam computed tomography. 61
30712957 2019
10
Suppression of SESN1 reduces cisplatin and hyperthermia resistance through increasing reactive oxygen species (ROS) in human maxillary cancer cells. 61
30300027 2018
11
Maxillary reconstruction using rectus femoris muscle flap and sagittal mandibular ramus/coronoid process graft pedicled with temporalis muscle. 61
30148478 2018
12
Evaluation of the osteoclastogenic process associated with RANK / RANK-L / OPG in odontogenic myxomas. 61
29680857 2018
13
Squamous cell carcinoma of the maxilla: Analysis of clinicopathological predictors for disease recurrence and metastatic behavior. 61
29459186 2018
14
Sudden shrinkage of free rectus abdominis musculocutaneous flap 15 years after maxilla reconstruction. 61
32158797 2018
15
Evaluation of coexistence of cancer and active tuberculosis; 16 case series. 61
29204340 2018
16
[Applicability of Pedicled Coronoid Process and Temporal Muscle(Fascial)Combined(PCPTM)Flap for Reconstruction of Orbital Floor Defect Following Hemi-Maxillectomy for Advanced Maxillary Cancer - A Report of Two Cases]. 61
29394859 2017
17
Maxillary Reconstruction Using Submental Artery Island Flap and Sagittal Mandibular Ramus/Coronoid Process Graft Pedicled With Temporalis Muscle. 61
28738192 2017
18
Use of the bioactive resorbable plate system for zygoma and zygomatic arch replacement and fixation with modified Crockett's method for maxillectomy: A technical note. 61
28685074 2017
19
Lymphatic drainage patterns of oral maxillary tumors: Approachable locations of sentinel lymph nodes mainly at the cervical neck level. 61
28006085 2017
20
Cerebellar Hemorrhage due to a Direct Carotid-Cavernous Fistula after Surgery for Maxillary Cancer. 61
28061497 2017
21
A Case of Maxillary Cancer Possibly Related to Exposure to Wood Dust and Formaldehyde. 61
27853061 2017
22
Sudden death after major head and neck cancer surgery due to undetected arrhythmogenic right ventricle cardiomyopathy (ARVC). 61
27357590 2016
23
Prognostic value of computed tomography characteristics for overall survival in patients with maxillary cancer. 61
27724942 2016
24
Can preoperative computed tomography predict tissue origin of primary maxillary cancer? 61
27749536 2016
25
[Maxillary Cancer with Metastasis to the Rouviere Nodes -- Complete Response to Chemoradiotherapy Using a Selective Intra-Arterial Infusion Technique]. 61
27067691 2016
26
Dental Implants in Oral Rehabilitation of A Maxillary Cancer Reconstruction: A Case Report. 61
24444340 2015
27
Suppression of Poly(rC)-Binding Protein 4 (PCBP4) reduced cisplatin resistance in human maxillary cancer cells. 61
26196957 2015
28
[Application of three-dimensional tumor mapping technique in diagnosis and treatment of malignant maxillary cancer]. 61
26178048 2015
29
Significant improvement in superselective intra-arterial chemotherapy for advanced paranasal sinus cancer by using indocyanine green fluorescence. 61
24318470 2014
30
Is elective neck dissection needed in clinically N0 neck in maxillary cancer? 61
25045635 2014
31
Maxillary reconstruction using chimeric flaps of the subscapular artery system without vein grafts and the novel usage of chimeric flaps. 61
24022603 2013
32
Aseptic meningitis: a rare side effect of cetuximab therapy. 61
22623275 2013
33
Management of the maxillary cancer patient--what the general dentist should know. 61
23909087 2013
34
[Use of the air-Q laryngeal airway and tube exchanger in a case of difficult tracheal extubation after maxillectomy]. 61
23157102 2012
35
Dosimetric and delivery characterizations of full-arc and half-arc volumetric-modulated arc therapy for maxillary cancer. 61
22843367 2012
36
Oral cancer in men and women: are there differences? 61
21052752 2011
37
Zygoma implant-supported prosthetic rehabilitation of a patient with a maxillary defect. 61
20728311 2011
38
Impact of superselective transarterial infusion therapy of high-dose cisplatin on maxillary cancer with orbital invasion. 61
20360344 2010
39
[Effectiveness of simultaneous combination therapy using S-1 and nedaplatin/radiation (SN therapy) for 4 cases of maxillary cancer]. 61
20495319 2010
40
Suppression of histone deacetylase 3 (HDAC3) enhances apoptosis induced by paclitaxel in human maxillary cancer cells in vitro and in vivo. 61
20417177 2010
41
Vascular supply with angio-CT for superselective intra-arterial chemotherapy in advanced maxillary sinus cancer. 61
20139264 2010
42
Facial paralysis after superselective intra-arterial chemotherapy via the middle meningeal artery in maxillary cancer. 61
19111999 2009
43
The combined analgesic effect of gabapentin and transdermal fentanyl patch on acute and chronic pain after maxillary cancer surgeries. 61
23139472 2009
44
[Application of modified pectoralis major myocutaneous island flap in head and neck surgeries]. 61
19484985 2009
45
[Clinical study of cervical lymph node metastasis in maxillary cancer patients]. 61
18634455 2008
46
[Intranasal sinus operation in palliative therapy in maxillary cancer patient--preliminary report]. 61
19205535 2008
47
Airway reconstruction with carrier-free cell sheets composed of autologous nasal squamous epithelium. 61
17713448 2007
48
[Dental implants in irradiated areas: a series of 33 patients]. 61
16804478 2006
49
[Cancer of maxillary mucosa (symptoms and diagnosis)]. 61
17159843 2006
50
Two cases of maxillary cancer with a similar clinical course and imaging findings but markedly different levels of FDG uptake. 61
16319642 2005

Variations for Maxillary Cancer

Expression for Maxillary Cancer

Search GEO for disease gene expression data for Maxillary Cancer.

Pathways for Maxillary Cancer

Pathways related to Maxillary Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 HDAC9 HDAC3
2 11.14 HDAC9 HDAC3
3
Show member pathways
10.97 HDAC9 HDAC3
4 10.72 HDAC9 HDAC3
5 10.49 HDAC9 HDAC3
6 10.1 HDAC9 HDAC3

GO Terms for Maxillary Cancer

Cellular components related to Maxillary Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone deacetylase complex GO:0000118 8.62 HDAC9 HDAC3

Biological processes related to Maxillary Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 circadian rhythm GO:0007623 9.26 TYMS HDAC3
2 histone deacetylation GO:0016575 9.16 HDAC9 HDAC3
3 histone H3 deacetylation GO:0070932 8.96 HDAC9 HDAC3
4 histone H4 deacetylation GO:0070933 8.62 HDAC9 HDAC3

Molecular functions related to Maxillary Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone deacetylase activity GO:0004407 9.16 HDAC9 HDAC3
2 protein deacetylase activity GO:0033558 8.96 HDAC9 HDAC3
3 NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0032041 8.62 HDAC9 HDAC3

Sources for Maxillary Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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